scholarly journals Reliability of SNIP test and optimal number of maneuvers in 6-11 years healthy children

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0252150
Author(s):  
Ana Aline Marcelino ◽  
Guilherme Fregonezi ◽  
Layana Marques ◽  
Ana Lista-Paz ◽  
Rodrigo Torres-Castro ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Optimal Number ◽  
Minimal Detectable Change ◽  
Healthy Children ◽  
Age Group ◽  
Older Children ◽  
Cross Sectional ◽  
Pediatric Populations

Background and purpose Sniff nasal inspiratory pressure (SNIP) is a voluntary inspiratory maneuver measured through a plug occluding one nostril. The investigation of the number of maneuvers necessary to reach the highest peak of SNIP in pediatric populations has been inconsistent. Thus, this study aimed to assess the reliability of SNIP in healthy children aged 6 to 11 years according to sex and age group, and to determine the optimal number of SNIP maneuvers for this age group. Methods This cross-sectional study included healthy children with normal pulmonary function. We performed 12 to 20 SNIP maneuvers, with a 30 s rest between each maneuver. The reliability was tested using the intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis for agreement. Results A total of 121 healthy children (62 girls [51%]) were included in this study. The ICC and corresponding confidence interval (CI) between the highest measure and the first reproducible maneuver were 0.752 (0.656–0.824), SEM = 10.37 cmH2O, and MDC = 28.74 cmH2O. For children aged 6 to 7 years, the ICC was 0.669 (0.427–0.822), SEM = 10.76 cmH2O and MDC = 29.82 cmH2O; for children aged 8 to 11 years, the ICC was 0.774 (0.662–0.852), SEM = 9.74 cmH2O, and MDC = 26.05 cmH2O. For girls, the ICC was 0.817 (0.706–0.889), SEM = 9.40 cmH2O and MDC = 26.05 cmH2O; for boys, the ICC was 0.671 (0.487–0.798), SEM = 11.51 cmH2O, and MDC = 31.90 cmH2O. Approximately 80% of the total sample reached the highest SNIP before the 10th maneuver. Conclusions SNIP demonstrated moderate reliability between the maneuvers in children aged 6 to 11 years; older children and girls reached the SNIP peak faster. Finally, results indicated that 12 maneuvers were sufficient for healthy children aged 6 to 11 years to achieve the highest SNIP peak.

scholarly journals Reliability of SNIP test in healthy children from 6 to 11 years.

2020 ◽  
Author(s):  
Ana Aline Marcelino ◽  
Guilherme Fregonezi ◽  
Layana Marques ◽  
Ana Lista-Paz ◽  
Rodrigo Torres-Castro ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Minimal Detectable Change ◽  
Healthy Children ◽  
Older Children ◽  
Cross Sectional ◽  
Residual Capacity ◽  
Pediatric Populations ◽  
Standard Error Of Measurement

Abstract Background Sniff nasal inspiratory pressure (SNIP) is a voluntary inspiratory maneuver measured through a plug occluding one nostril. The investigation of the number of maneuvers necessary to reach the highest peak of SNIP in pediatric populations has been inconsistent. Thus, our goal was to assess the reliability SNIP in healthy children aged 6 to 11 years and compare with regard to sex and age group, as well as to determine the adequate number of maneuvers. Methods This cross-sectional study included healthy children with normal pulmonary function. Were performed 12 to 20 maneuvers SNIP near functional residual capacity, with a 30 s rest between each. Reliability was tested using intraclass correlation coefficient (ICC), standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis for agreement. Results A total of 121 children (62 girls [51%]) were included. The ICC and corresponding confidence interval (CI) between the highest measure and the first reproducible maneuver was 0.752 (0.656–0.824), SEM of 10.37 cmH2O and MDC of 28.74 cmH2O. For children aged 6–7 and 8–11 years, the ICC (CI) was 0.669 (0.427–0.822), SEM = 10.76 cmH2O and MDC = 29.82 cmH2O, and 0.774 (0.662–0.852), with SEM = 9.74 cmH2O and MDC = 26.05 cmH2O, respectively. For girls, the ICC (CI) was 0.817 (0.706–0.889), SEM = 9.40 cmH2O and MDC = 26.05 cmH2O; for boys, 0.671 (0.487–0.798), SEM = 11.51 cmH2O and MDC = 31.90 cmH2O. Approximately 80% of the total sample reached the highest SNIP before the 10th maneuver. Conclusions SNIP demonstrated moderate reliability between the maneuvers in children aged 6 to 11 years. Otherwise, older children and girls reached the SNIP peak faster. Finally, results suggested that 12 maneuvers were sufficient for healthy children aged 6 to 11 years to achieve the highest SNIP peak.

Health Status of Senior Citizens: A Cross-sectional study

2020 ◽  
Vol 11 (01) ◽  
Author(s):  
Priyanka Beniwal ◽  
Chandrakala Singh
Keyword(s):  
Health Status ◽  
Senior Citizens ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Age Group ◽  
Poor Health Status ◽  
Cross Sectional ◽  
Males And Females ◽  
The Individual ◽  
Average Health

Aging is a series of processes that begin with life and continue throughout the lifecycle. It represents the closing period in the lifespan, a time when the individual looks back on life, lives on past accomplishments and begins to finish off his life course. It represents the accumulation of changes in person over time. The study aims to investigate the health status of senior citizens. The present study was carried out in Hisar and Sirsa district of Haryana state. A total of 400 elderly equally representing both males and females of age group 65-70 years were selected randomly for the study. Modified inventory developed by Khan and Lal (2011) was used to assess health status of senior citizens. The results of the study elucidated that health status of senior citizens depicted that 54.25 per cent of the total respondents had average health status followed by good (25.25%) and poor health status (20.50%). The most common health problems reported by the senior citizens were joint pains, back pains, blood pressure, and chest pain etc. Gender wise comparison of total sample further pointed out that females were poor in their health against males.

P055 Title: Standard rate of ASLO in healthy children with streptococcal (angina) or post-streptococcal (RAA) infection in Morocco

Rheumatology ◽  
2021 ◽  
Vol 60 (Supplement_5) ◽  
Author(s):  
Himri Sara ◽  
Oumokhtar Bouchra ◽  
El Fakir Samira ◽  
Atmani Samir
Keyword(s):  
Urban Areas ◽  
Geographic Location ◽  
Cross Sectional Study ◽  
Critical Threshold ◽  
Healthy Children ◽  
Age Group ◽  
Normal Children ◽  
Cross Sectional ◽  
Standard Rate ◽  
Group 2

Abstract Background The antistreptolysins O “ASLO” are anti streptococcal antibodies directed against streptolysin O. The assay of ASLO can provide proof of infection of streptococcal origin. However, it cannot confirm the presence of RAA or the degree of severity of the disease. A level of ASLO less than or equal to a critical threshold of 200 IU/ml is considered normal in children. Several factors influence the ASLO title and therefore their standard rate such as age, geographic location and seasonal variation. The objective of this study is to determine the upper normal limit (ULN) of ASLO in healthy children with angina or RAA at the CHU Hassan II of Fez in Morocco. Methods This is a cross-sectional study carried out from January 2016 to July 2019 in the cardiopediatric unit of CHU Hassan II and the Anarjiss health center in Fez. Patients below 18 years of age were included in this study. The children are classified into 3 groups: group 1: 152 children with RAA and who are diagnosed according to the modified Jones criteria, group 2: 177 children with angina, group 3: 157 healthy children who did not have an RAA, a history of recurrent or recent pharyngitis. Patient data is collected on operating sheets. Statistical analysis was performed using SPSS v 21 software. To establish a normal upper limit for ASLOs, the 90 percentile was used as it is a value below which at least 90% of cases studied in each group. Results The most common age group in the 3 groups is the age group between 5 and 15 years old. The frequency of children of urban origin is greater than that of rural origin in all the groups studied. The ULN is 421.4U/ml in the group of normal children, 641.95 U/ml in the RAA group and 561.8 U/ml in the group of children with pharyngitis. The study of changes in ASLO rates over time shows that they increase significantly in angina and tend to decrease in RAA. The LSN of ASLOs by gender shows that it is higher for boys than for girls. The ULN according to the residence shows that it is higher in urban areas. As well as the LSN of ASLO according to the season shows that it is higher in the cold period, especially in winter and spring (P < 0.001). With regard to age, the ULN of ASLOs is higher in the 5–15 age group. Conclusion In this study, it can be concluded that an ASLO level less than or equal to 400 U/ml is the critical threshold in a normal child, while an ASLO level >400 U/ml is considered pathological in children. children in Morocco.

scholarly journals Development and evaluation of a diet quality screener to assess adherence to the Dutch food-based dietary guidelines

2021 ◽  
pp. 1-28
Author(s):  
Mariëlle G de Rijk ◽  
Anne I Slotegraaf ◽  
Elske M Brouwer-Brolsma ◽  
Corine WM Perenboom ◽  
Edith JM Feskens ◽  
...  
Keyword(s):  
Diet Quality ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Dietary Guidelines ◽  
Full Length ◽  
Cross Sectional ◽  
Maximum Score ◽  
The Mean ◽  
Excellent Reproducibility

Abstract The Eetscore FFQ was developed to score the Dutch Healthy Diet index 2015 (DHD2015-index) representing the Dutch food-based dietary guidelines of 2015. This paper describes the development of the Eetscore FFQ, a short screener assessing diet quality, examines associations between diet quality and participants’ characteristics, and evaluates the relative validity and reproducibility of the Eetscore FFQ in a cross-sectional study with Dutch adults. The study sample consisted of 751 participants, aged 19-91 y, recruited from the EetMeetWeet research panel. The mean DHD2015-index score based on the Eetscore FFQ of the total sample was 111 (SD 17.5) out of a maximum score of 160 points and was significantly higher in women than in men, positively associated with age and education level, and inversely associated with BMI. The Kendall’s tau-b coefficient of the DHD2015- index between the Eetscore FFQ and the full-length FFQ (on average 1.7-month interval, n=565) was 0.51 (95% CI 0.47, 0.55), indicating an acceptable ranking ability. The intraclass correlation coefficient (ICC) between DHD2015-index scores derived from two repeated Eetscore FFQs (on average 3.8-month interval, n=343) was 0.91 (95% CI: 0.89, 0.93) suggesting a very good reproducibility. In conclusion, the Eetscore FFQ was considered acceptable in ranking participants according to their diet quality compared with the full-length FFQ and showed good to excellent reproducibility.

scholarly journals Does Intramedullary Nailing for Distal Fibular Fractures Restore Anatomic Parameters and Syndesmotic Relationship?

2020 ◽  
Vol 5 (2) ◽  
pp. 2473011420S0000
Author(s):  
Natalio R. Cuchacovich Mikenberg ◽  
Francisco J. Bravo Gallardo ◽  
Esteban Giannini ◽  
Claudia Astudillo ◽  
Manuel J. Pellegrini ◽  
...  
Keyword(s):  
Statistical Power ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Wilcoxon Test ◽  
Medium Size ◽  
Control Group ◽  
Cross Sectional ◽  
Rotation Length ◽  
Paired Control

Category: Trauma; Ankle Introduction/Purpose: Fibular nailing (FN) is a method of fixation that has proven to be useful for the treatment of distal fibular fractures (DF). FN minimizes soft tissue complications, provides similar stability compared to plating with less hardware related symptoms. Nevertheless, FN has been associated with syndesmotic malreduction and incapacity of restoring length and rotation of the fibula. We aimed to evaluate the fibular and syndesmotic reduction after fixation with FN compared to the uninjured ankle. Methods: Prospective cohort, cross-sectional study with a paired control group. Patients with DF fractures treated with FN between January 2017 and July 2019 were included. Immediate postoperative bilateral Ankle CT was obtained in all cases. Two independent radiologists performed all the measurements on both ankles (fibular rotation, length, translation, and syndesmotic diastasis. Statistical analysis was made using the Wilcoxon Test and Intraclass correlation coefficient (ICC). Considering a medium size sample effect, 95% confidence with .05 alpha error, a total sample of 26 subjects were needed to achieve a .80 of statistical power (G-Power 3.1). All analyses were performed using SPSS V20. Results: Twenty-six patients were included (14 Women). The mean age was 47 years (18-91). No statistically significant differences were identified considering fibular rotation (p:0,694), fibular length (p:0,585) and syndesmotic diastasis (p:0,078) between the injured and uninjured ankle. Fibular translation has statistical differences (p:0,043). The ICC shows an excellent concordance between radiologists except for Fibular translation (ICC 0,47) Conclusion: In this cohort, fixation of DF fractures with FN allows restoration of anatomical parameters of the ankle in terms of fibular rotation, length, and syndesmotic diastasis. However, Fibular translation had significant differences compared with the uninjured ankle.

scholarly journals Children with metabolically healthy obesity have a worse metabolic profile compared to normal weight peers: a cross-sectional study

2021 ◽  
Author(s):  
Anastasios Serbis ◽  
Vasilieios Giapros ◽  
Stavroula A. Paschou ◽  
Ekaterini Siomou
Keyword(s):  
Metabolic Profile ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Age Group ◽  
Z Score ◽  
Metabolically Healthy Obesity ◽  
Cross Sectional ◽  
Pediatric Populations ◽  
Metabolically Healthy ◽  
Metabolically Unhealthy Obesity

Abstract Purpose: A phenotype of metabolically healthy obesity (MHO) has been described in youth with obesity, but data are still scarce in this age group. The aim of the current study was to describe and compare clinical and laboratory parameters related to obesity among three different groups of youth, namely youth with normal weight (NW), with MHO, and with metabolically unhealthy obesity (MUO). Methods: 103 youngsters with obesity were divided according to 2018 consensus-based criteria into those with MHO [n=49, age (± SD): 10.9 ± 2.9 years] and those with MUO [n=54, 11.5 ± 2.7 years] and were compared to age-, sex- and Tanner-matched NW [n=69, 11.3 ± 2.9 years]. Several obesity related parameters were investigated for both groups of children. Comparisons were made by analysis of variance (ANOVA) followed by the Fisher’s PLSD test. Results: Youth with MHO had lower systolic (p<0.001) and diastolic (p<0.01) blood pressure z-score and triglycerides (p<0.01), but higher HDL-C (p<0.001), total cholesterol (p<0.05), and apo-A1 (p<0.05) compared to those with MUO. Compared to controls, both children with MHO and MUO showed higher fasting insulin (p<0.05), HOMA-IR (p<0.05) and QUICKI (p<0.001). Similarly, both groups had higher hsCRP, fibrinogen, uric acid, and leptin compared to controls (for all, p<0.001), while their adiponectin was lower (p<0.05). Visfatin was higher in children with MUO compared to controls (p<0.01), and it showed a trend to be lower in children with MHO compared to those with MUO (p=0.1).Conclusion: This study provides evidence that children identified as having MHO by the consensus-based criteria had better metabolic profile than youth with MUO, but worse than NW. Further research is needed in pediatric populations both regarding MHO criteria and the nature of the MHO phenotype per se.

scholarly journals In-Out-Test: A New Paradigm for Sorting the Wheat from the Chaff in Prodromal Alzheimer’s Disease

2019 ◽  
Vol 67 (1) ◽  
pp. 265-277
Author(s):  
Eduardo Torrealba ◽  
Pilar Garcia-Morales ◽  
Juan Carlos Cejudo ◽  
Mario Diaz ◽  
Francisco Rodriguez-Esparragon ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Intraclass Correlation ◽  
Total Sample ◽  
Cross Sectional Study ◽  
New Paradigm ◽  
Progressive Dementia ◽  
Cross Sectional ◽  
Prodromal Alzheimer’S Disease ◽  
Selective Reminding Test

Background: Assessment of hippocampal amnesia is helpful to distinguish between normal cognition and mild cognitive impairment (MCI), but not for identifying converters to dementia. Here biomarkers are useful but novel neuropsychological approaches are needed in their absence. The In-out-test assesses episodic memory using a new paradigm hypothesized to avoid reliance on executive function, which may compensate for damaged memory networks. Objective: To assess the validity of the In-out-test in identifying prodromal Alzheimer’s disease (PAD) in a clinical setting, by comparing this to the Free and Cued Selective Reminding Test (FCSRT) and cerebrospinal fluid biomarkers. Methods: A cross-sectional study of 32 cognitively healthy, 32 MCI, and 30 progressive dementia subjects. All participants were given both the In-out-test and the FCSRT; 40 of them also received a lumbar puncture. Results: Internal consistency was demonstrated using Cronbach Alpha (r = 0.81) and Inter-rater reliability with Kappa (k = 0.94). Intraclass correlation (ICC) for test-retest reliability: r = 0.57 (p = 0.57). ICC between the In-out-test and FCSRT r = 0.87 (p = 0.001). ICC between the In-out-test and Aβ42 and P-tau/Aβ42 for controls: 0.73 and 0.75, respectively; P-tau for MCI: 0.77 and total sample: 0.70; Aβ42 for dementia: 0.71. All ICC measures between FCSRT and biomarkers were ≤0.264. AD diagnosis: In-out-test k = 0.71; FCSRT k = 0.49. PAD diagnosis (N = 35): In-out-test k = 0.69; FCSRT k = 0.44. Conclusions: The In-out-test detected prodromal AD with a higher degree of accuracy than a conventional hippocampal-based memory test. These results suggest that this new paradigm could be of value in clinical settings, predicting which patients with MCI will go on to develop AD.

scholarly journals Frequency of symptoms associated with gallstone disease: a hospital-based cross sectional study

2018 ◽  
Vol 28 (2) ◽  
Author(s):  
Leila Kanafi Vahed ◽  
Leila Khedmat
Keyword(s):  
Gallstone Disease ◽  
Oral Contraceptive Pill ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Abdominal Quadrant

This study investigated the likely outcomes of gallstone disease and frequency of symptoms associated with this. This cross sectional study was performed at the Aliebn Abitaleb hospital in Rafsanjan over a period of twelve months from 2000 to 2001. A total sample of 70 individuals were included in the study, interviewing them using of a questionnaire covering data in terms of demographic features and medical history.The majority of patients belonged to the age group of 41 to 60 years (44.3% of all patients), while the lowest frequency was in the age group of 20 years or less. Frequency of females was higher than males. The frequency of female patients increased with the number of child birth, the highest being in women who had more than 5 child births. The most common complaint of pain was revealed as upper right abdominal quadrant (RUQ), which accounted for 95.7% of cases. Vomiting was observed in 52.9% of patients. In addition, the frequency of patients with chronic pain initiation was more than those with acute pain initiation. Among women, 17.5% had oral contraceptive pill constipation. It is worth noting that ultrasonography was the best diagnostic tool for evaluating patients. It is noteworthy that the most common symptom was right upper quadrant tenderness. Our data indicate that diabetes was the most common illness associated with gallstone disease and that 8.6% of patients had a family history of gallstone disease.

scholarly journals Quality of life can be good after slide tracheoplasty for long-segment tracheal stenosis

2019 ◽  
Vol 29 (6) ◽  
pp. 876-882
Author(s):  
Jo Wray ◽  
Matthew Ryde ◽  
Colin R Butler ◽  
Richard J Hewitt
Keyword(s):  
Quality Of Life ◽  
Tracheal Stenosis ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Older Children ◽  
Cross Sectional ◽  
Slide Tracheoplasty ◽  
Parents And Children ◽  
Related Quality

Abstract OBJECTIVES The objectives of this study were to measure ‘health-related quality of life’ (HRQoL) in children following slide tracheoplasty for long-segment tracheal stenosis (LSTS) and to explore the relationship of comorbidities and parental mental health with HRQoL outcomes. METHODS A cross-sectional study was undertaken with children who had undergone slide tracheoplasty. Participants included parents and children (age 5–15 years) recruited over a 13-month period, who were asked to complete validated measures of HRQoL, development and behaviour. Scores were compared to published norms. RESULTS Forty-two children (male 69%; n = 29) were included; mean age was 5.3 (standard deviation 3.5) years and mean follow-up was 45 (range 4–179) months. Mean total HRQoL scores for children with repaired LSTS did not differ from those of healthy norms other than for children aged 13–23 months, but 10 children (24%) had scores &gt;2 SD below the mean for healthy children. HRQoL was poorer in children with non-cardiac congenital comorbidities than in those with isolated LSTS (mean scores 60.34 ± 17.19 and 85.52 ± 12.19, respectively, P = 0.01). There was good agreement between children’s and parents’ scores, although children rated their HRQoL as better than their parents did. Anxious parents rated their children’s HRQoL as significantly worse than non-anxious parents (P&lt;0.001). CONCLUSIONS Older children with isolated LSTS can have excellent HRQoL after surgery. Younger children, at an earlier time point postoperatively, and those with non-cardiac congenital comorbidities have poorer HRQoL. Further longitudinal evaluation is required to identify psycho-social (including parental) predictors of outcome which may inform, or be amenable to, intervention.

scholarly journals ACUTE CHANGES IN PHYSICAL ACTIVITY ASSOCIATED WITH HOME CONFINEMENT DUE TO COVID-19: A RETROSPECTIVE CROSS-SECTIONAL STUDY IN A COLLEGIATE POPULATION IN GREECE

2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Eirini Manthou ◽  
Anastasios Fotiou ◽  
Eleftheria Kanavou ◽  
George Pigos ◽  
Vasilios I. Kalapotharakos
Keyword(s):  
Physical Activity ◽  
Online Survey ◽  
Short Form ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Age Group ◽  
Cross Sectional ◽  
Younger Age ◽  
Gender And Age ◽  
Acute Changes

Background: In March 2020 home confinement was imposed to Greek residents as a measure to abate the COVID-19 pandemic. This study aims to elucidate changes in physical activity (PA) levels that occurred during confinement in a collegiate population in Greece. Methods: 565 collegiate students and staff participated in a retrospective cross-sectional online survey measuring PA related behaviours before and during the confinement period using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Results: The overall activity (IPAQ-SF MET-min score) decreased in the confinement- compared to the pre-confinement period [Md (Q1:Q3) pre vs. during: 2464 (1160; 5126) vs. 2247 (1074; 3999), p<0.001], driven exclusively by males (p<0.001) and the younger age group (18-31 years; p=0.003). Sitting increased in the total sample, including in each gender and age-group (all p<0.001). Compared to pre-confinement period, during confinement the odds of being in the ‘medium’ or ‘high’ moderate- to- vigorous PA group were 41% higher in females (aOR = 1.41, 95% CI=1.11-1.80, p=0.006) and 33% lower in males (aOR=0.67, 95% CI=0.50-0.88, p=0.005). Conclusion: There is a gendered pattern in observed changes in PA during the Covid-19 home confinement in the collegiate population, with females being those favored in comparison to males. <p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0790/a.php" alt="Hit counter" /></p>

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