scholarly journals Loss of years of healthy life due to road incidents of motorcyclists in the city of Medellin, 2012 to 2015

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256758
Author(s):  
Sandra Milena Porras Cataño ◽  
Hugo Grisales-Romero
Keyword(s):  
Age Groups ◽  
Premature Death ◽  
Years Of Life Lost ◽  
Healthy Life ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Years Lived With Disability ◽  
National Road ◽  
The City ◽  
Proportional Distribution

Objective Determine the loss of years of healthy life due to road incidents of motorcyclists in the city of Medellin from 2012 to 2015. Methods Descriptive study with data on health care of injured motorcyclists and deaths adjusted with the Preston and Coale method, and OPS proportional distribution for the period 2012–2015. The years of life lost due to premature death (YLLs), years lived with disability (YLDs), and the disability-adjusted life years (DALYs) were calculated according to the new methodology designed for that purpose. Results The loss of years of healthy life due to road incidents of motorcyclists in the four-year period was 80,046 DALYs (823.8 per 100,000 inhabitants), with a higher proportion in men (81.3% and a ratio of 5 to 1 compared to women); the YLDs was 66.6% with marked differences in favor of men. There was nearly a 38% difference in the ages of 15 to 19 as well as a 19% difference from 30 to 49, compared to women. Premature death (YLLs) contributed to 33.4% of DALYs, with significant presentation in the above-mentioned age groups. Conclusions The greatest loss of years of healthy life due to road incidents of motorcyclists in Medellin was due to non-fatal injuries and was concentrated in young men. If the trend of motorcycle road incidents continues, both local and national road safety plans will fail to accomplish the expected results, especially among motorcycle users.

scholarly journals Estimating Disability-Adjusted Life Years (DALYs) in Community Cases of Norovirus in England

Viruses ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 184
Author(s):  
John P Harris ◽  
Miren Iturriza-Gomara ◽  
Sarah J O’Brien
Keyword(s):  
Gastrointestinal Diseases ◽  
Years Of Life Lost ◽  
Disability Adjusted Life Years ◽  
Healthy Life ◽  
England And Wales ◽  
Infected People ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Years Lived With Disability

Disability adjusted life years (DALYs) have been used since the 1990s. It is a composite measure of years of life lost with years lived with disability. Essentially, one DALY is the equivalent of a year of healthy life lost if a person had not experienced disease. Norovirus is the most common cause of gastrointestinal diseases worldwide. Norovirus activity varies from one season to the next for reasons not fully explained. Infection with norovirus is generally not severe, and is normally characterized as mild and self-limiting with no long-term sequelae. In this study, we model a range of estimates of DALYs for community cases of norovirus in England and Wales. We estimated a range of DALYs for norovirus to account for mixing of the severity of disease and the range of length of illness experienced by infected people. Our estimates were between 1159 and 4283 DALYs per year, or 0.3–1.2 years of healthy life lost per thousand cases of norovirus. These estimates provide evidence that norovirus leads to a considerable level of ill health in England and Wales. This information will be helpful should candidate norovirus vaccines become available in the future.

scholarly journals The burden of atherosclerosis in Portugal

2020 ◽  
Author(s):  
João Costa ◽  
Joana Alarcão ◽  
Francisco Araujo ◽  
Raquel Ascenção ◽  
Daniel Caldeira ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Clinical Manifestations ◽  
Premature Death ◽  
Mortality Data ◽  
Years Of Life Lost ◽  
Disability Adjusted Life Years ◽  
Mainland Portugal ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Years Lived With Disability

Abstract Aims This article sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016. Methods and results The burden of atherosclerosis was measured in disability-adjusted life years following the latest 2010 Global Burden of Disease (GBD) methodology. Disability-adjusted life years were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clinical manifestations of atherosclerosis were included: ischaemic heart disease (IHD) (including acute myocardial infarction, stable angina, and ischaemic heart failure), ischaemic cerebrovascular disease (ICVD), and peripheral arterial disease (PAD). Years of life lost were estimated based on all-cause mortality data for the Portuguese population and mortality due to IHD, ICVD, and PAD for the year 2016 sourced from national statistics. Standard life expectancy was sourced from the GBD study. Years lived with disability corresponded to the product of the number of prevalent cases by an average disability weight for all possible combinations of disease. Prevalence data for the different clinical manifestations of atherosclerosis were sourced from epidemiological studies. Disability weights were sourced from the published literature. In 2016, 15 123 deaths were attributable to atherosclerosis, which corresponded to 14.3% of overall mortality in mainland Portugal. Disability-adjusted life years totalled 260 943, 75% due to premature death (196 438 YLL) and 25% due to disability (64 505 YLD). Conclusion Atherosclerosis entails a high disease burden to society. A large part of this burden would be avoidable if evidence-based effective and cost-effective interventions targeting known risk factors, from prevention to treatment, were implemented.

scholarly journals 1442The burden of COVID-19 in Australia in 2020

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Lynelle Moon ◽  
Anna Reynolds ◽  
Michelle Gourley
Keyword(s):  
Burden Of Disease ◽  
Disease Burden ◽  
Years Of Life Lost ◽  
Disability Adjusted Life Years ◽  
Australian Population ◽  
Healthy Life ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Years Lived With Disability ◽  
The Impact

Abstract Background During 2020, there were nearly 28,500 cases of COVID-19 in Australia. Burden of disease estimates for COVID-19 have not been calculated for the Australian population. Burden of disease data on COVID-19 provide valuable information on the impact of the disease, including both fatal and non-fatal effects. Methods Burden of disease is measured using the summary measure disability-adjusted life years (DALYs). One DALY is 1 year of ‘healthy life’ lost due to illness (Years Lived with Disability) and/or death (Years of Life Lost)—the more DALYs associated with a disease or injury, the greater the burden. The analysis draws on Australian deaths, incidence and severity, as well as methods and other inputs developed in other countries reflecting current understanding about this new disease. Results There were over 8,300 DALYs lost due to COVID-19 in 2020 in Australia; 97% of the disease burden arose from fatal cases. Males lost an average of 10.7 years, and females 8.1 years, due to dying from COVID-19, using an aspirational life expectancy. The burden of disease estimates for Australia for COVID-19 are much lower than the leading diseases causing burden. Conclusions The relatively low burden for COVID-19 in Australia in 2020 compared to other diseases and other countries reflects the success Australia had in containing the virus. Key messages Most of the burden due to COVID-19 in Australia was fatal. Burden of disease estimates for COVID-19 in Australia for 2020 are much lower than the leading diseases.

scholarly journals Estimation of Burden of Cystic Echinococcosis in Iran Using Disability Adjusted Life Years (DALYs) in 2018

2021 ◽  
Author(s):  
Fateme Parandin ◽  
Fatemeh Heydarpour ◽  
Mehdi Mohebali ◽  
Ahmad Ali Hanafi-Bojd ◽  
Ali Akbari Sari ◽  
...  
Keyword(s):  
Premature Death ◽  
Years Of Life Lost ◽  
Disability Adjusted Life Years ◽  
Public Concern ◽  
Policy Makers ◽  
Control Programs ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Standard Life ◽  
And Control

Background: Human hydatidosis as a public concern has increased in a number of countries that have reduced control programs for the disease due to lack of resources or policies. We aimed to estimate Disability-Adjusted Life Years (DALYs) for human hydatidosis in Iran in 2018. Methods: Data were collected from the Center of Communicable Diseases Control, Ministry of Health &Medical Education, Tehran, Iran in 2018. To calculate DALYs, years of life lost due to premature death (YLL) with years of life with disability (YLD) were calculated according to the formula as DALY = YLL + YLD. The standard life expectancy lost method (SEYLL) was used to calculate the years lost due to premature death. Results: DALYs for human hydatidosis was calculated as 1210.12 years (YLD equals to 177.12 and YLL equals to 1033) in Iran for the year 2018. It was estimated to be 700.2 years for men and 509.8 years for women.  DALYs in men were significantly different from women (P= 0.001) so DALYs were more in men than women were. YLD was calculated at 78.228 years in men and 98.892 years in women and in both men and women at 177.12 years. YLD was significantly different in women compared to men (P=0.001), so YLD in women was more than in men. Conclusion: We reached considerable indices for hydatidosis in our study. Therefore, disease prevention and control programs in Iran seem necessary by the policy makers.

scholarly journals Burden of Multiple Sclerosis in Eastern Mediterranean Region (1990-2016): Findings From the 2016 Global Burden of Disease Study

2019 ◽  
Author(s):  
Mohammad Ali Sahraian ◽  
Pouria Heydarpour ◽  
Maziar Moradi-Lakeh ◽  
Sharareh Eskandarieh ◽  
Seyed-Mohammad Fereshtehnejad ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Eastern Mediterranean Region ◽  
Years Of Life Lost ◽  
Effective Interventions ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study ◽  
Years Lived With Disability

AbstractBackgroundMultiple sclerosis (MS) is among the leading causes of disability in Young Adults worldwide. Current estimates of MS burden in Eastern Mediterranean Region (EMR) are necessary for planning effective interventions .To estimate Prevalence, incidence, mortality, years lived with disability (YLDs), years of life lost (YLLs) and disability-adjusted life-years (DALYs) in EMR by country age, and sex from 1990 to 2016.MethodsWe estimated regional and country-specific prevalence, incidence, mortality, DALYs, YLLs, and YLDs for MS. DALYs were computed as the sum of YLDs and YLLs.ResultsTotal DALYs in EMR countries was 12,810 in 1990 for males and increased to 36,391 in 2016 and from 18,962 to 53,851 for females. Lowest DALYs in both sexes were observed in Somalia (248) while the highest were in Iran (26,394). YLDs in males increased from 6,511 in 1990 to 19,515 in 2016, and in females from 12,247 to 33,937. The highest age-standardized prevalence, incidence, YLDs and DALYs were in Iran (72.11, 2.49, 18.03, and 32.5, respectively).ConclusionsOur findings provide valuable information to guide the development and implementation of measures to address the rising burden of MS and it consequences in the EMR countries.

The prevalence and burden of mental and substance use disorders in Australia: Findings from the Global Burden of Disease Study 2015

2018 ◽  
Vol 52 (5) ◽  
pp. 483-490 ◽  
Author(s):  
Liliana G Ciobanu ◽  
Alize J Ferrari ◽  
Holly E Erskine ◽  
Damian F Santomauro ◽  
Fiona J Charlson ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Years Of Life Lost ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study ◽  
Years Lived With Disability

Objectives: Timely and accurate assessments of disease burden are essential for developing effective national health policies. We used the Global Burden of Disease Study 2015 to examine burden due to mental and substance use disorders in Australia. Methods: For each of the 20 mental and substance use disorders included in Global Burden of Disease Study 2015, systematic reviews of epidemiological data were conducted, and data modelled using a Bayesian meta-regression tool to produce prevalence estimates by age, sex, geography and year. Prevalence for each disorder was then combined with a disorder-specific disability weight to give years lived with disability, as a measure of non-fatal burden. Fatal burden was measured as years of life lost due to premature mortality which were calculated by combining the number of deaths due to a disorder with the life expectancy remaining at the time of death. Disability-adjusted life years were calculated by summing years lived with disability and years of life lost to give a measure of total burden. Uncertainty was calculated around all burden estimates. Results: Mental and substance use disorders were the leading cause of non-fatal burden in Australia in 2015, explaining 24.3% of total years lived with disability, and were the second leading cause of total burden, accounting for 14.6% of total disability-adjusted life years. There was no significant change in the age-standardised disability-adjusted life year rates for mental and substance use disorders from 1990 to 2015. Conclusion: Global Burden of Disease Study 2015 found that mental and substance use disorders were leading contributors to disease burden in Australia. Despite several decades of national reform, the burden of mental and substance use disorders remained largely unchanged between 1990 and 2015. To reduce this burden, effective population-level preventions strategies are required in addition to effective interventions of sufficient duration and coverage.

scholarly journals The disvalue of death in the global burden of disease

2017 ◽  
Vol 44 (3) ◽  
pp. 192-198 ◽  
Author(s):  
Carl Tollef Solberg ◽  
Ole Frithjof Norheim ◽  
Mathias Barra
Keyword(s):  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Years Of Life Lost ◽  
Loss Of Life ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Life Itself ◽  
Disease Study ◽  
Years Lived With Disability

In the Global Burden of Disease study, disease burden is measured as disability-adjusted life years (DALYs). The paramount assumption of the DALY is that it makes sense to aggregate years lived with disability (YLDs) and years of life lost (YLLs). However, this is not smooth sailing. Whereas morbidity (YLD) is something that happens to an individual, loss of life itself (YLL) occurs when that individual’s life has ended. YLLs quantify something that involves no experience and does not take place among living individuals. This casts doubt on whether the YLL is an individual burden at all. If not, then YLDs and YLLs are incommensurable. There are at least three responses to this problem, only one of which is tenable: a counterfactual account of harm. Taking this strategy necessitates a re-examination of how we count YLLs, particularly at the beginning of life.

scholarly journals The Burden of Stroke in The Municipality of Chongqing, China, From 1990 To 2016

2020 ◽  
Author(s):  
Shiya Yang ◽  
Sha Ran ◽  
Ping Liu ◽  
Zuocheng Wu ◽  
Dong Yu ◽  
...  
Keyword(s):  
Temporal Trends ◽  
Age Groups ◽  
Health Resources ◽  
Mortality Rates ◽  
Western China ◽  
Years Of Life Lost ◽  
Prevalence Rates ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study

Abstract Background: The burden of stroke varies substantially across regions in China. However, comprehensive comparisons between regions are lacking. This study aims to analyze variations in stroke burden in the municipality of Chongqing, Western China, from 1990-2016. Methods: Data on prevalence, years lived with disability (YLDs), mortality, years of life lost (YLLs), and disability-adjusted life years (DALYs) by age, sex, location, and year were extracted from the 2016 Global Burden of Disease Study (GBD 2016) of China between 1990-2016. The datasets were compared to examine the temporal trends in stroke burden in the last two decades.Results: In 2016, there were 670,438 cases of stroke, 41,022 deaths, and 847,437 DALYs due to stroke in Chongqing. Age-standardized mortality and DALY rates of IS and HS were higher in men whereas age-standardized prevalence rates of IS were higher in women. From 1990 to 2016, age-standardized prevalence rates of overall stroke increased by 33.29%, whereas mortality rates and DALYs decreased by 34.51% and 34.79%, respectively. YLLs were the main contributor to DALYs; however, the YLL/YLD ratio decreased over time. During the study period, the overall burden of stroke decreased, whereas the prevalence rate of IS increased in all age groups.Conclusions: Despite a decrease in mortality rates, the increase in the prevalence of stroke in Chongqing stresses the need to allocate more health resources. Special attention should be paid to discrepancies in the estimation of the type of stroke according to gender and age to determine mechanisms that explain the causes of stroke.

Global burden of diabetes and depression

2018 ◽  
Author(s):  
Julio Licinio ◽  
Andreas L. Birkenfeld ◽  
Stefan R. Bornstein
Keyword(s):  
Premature Death ◽  
First Century ◽  
Disability Adjusted Life Years ◽  
Average Life ◽  
Average Life Expectancy ◽  
Ongoing Research ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Years Lived With Disability ◽  
Specific Country

Diabetes and depression are two of the major global health concerns in the twenty-first century. One way of measuring the global impact of these illnesses are the disability-adjusted life-years or DALYs. The calculation takes into account the average life expectancy of a specific country, the years lost by premature death, and the years lived with disability/disease. Furthermore, ongoing research has shown that interactions exist between depression and diabetes. Diabetes and other chronic diseases can lead to depression, while depression can increase the risk for developing diabetes or worsen the course of diabetes. In this book, the current understanding of the interactions between depression and diabetes will be discussed, highlighting various pathways in which these morbidities are linked. In addition, the authors give outlooks on how diabetes and depression might be treated in the future.

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