scholarly journals Dreaming of the sleep lab

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257738
Author(s):  
Claudia Picard-Deland ◽  
Tore Nielsen ◽  
Michelle Carr
Keyword(s):  
De Novo ◽  
Sleep Stage ◽  
Formation Mechanisms ◽  
Sleep Study ◽  
The Past ◽  
Current State ◽  
Local Space ◽  
Trait Factors ◽  
Near Future ◽  
New Scoring

The phenomenon of dreaming about the laboratory when participating in a sleep study is common. The content of such dreams draws upon episodic memory fragments of the participant’s lab experience, generally, experimenters, electrodes, the lab setting, and experimental tasks. However, as common as such dreams are, they have rarely been given a thorough quantitative or qualitative treatment. Here we assessed 528 dreams (N = 343 participants) collected in a Montreal sleep lab to 1) evaluate state and trait factors related to such dreams, and 2) investigate the phenomenology of lab incorporations using a new scoring system. Lab incorporations occurred in over a third (35.8%) of all dreams and were especially likely to occur in REM sleep (44.2%) or from morning naps (48.4%). They tended to be related to higher depression scores, but not to sex, nightmare-proneness or anxiety. Common themes associated with lab incorporation were: Meta-dreaming, including lucid dreams and false awakenings (40.7%), Sensory incorporations (27%), Wayfinding to, from or within the lab (24.3%), Sleep as performance (19.6%), Friends/Family in the lab (15.9%) and Being an object of observation (12.2%). Finally, 31.7% of the lab incorporation dreams included relative projections into a near future (e.g., the experiment having been completed), but very few projections into the past (2.6%). Results clarify sleep stage and sleep timing factors associated with dreamed lab incorporations. Phenomenological findings further reveal both the typical and unique ways in which lab memory elements are incorporated de novo into dreaming. Identified themes point to frequent social and skillful dream scenarios that entail monitoring of one’s current state (in the lab) and projection of the self into dream environments elaborated around local space and time. The findings have implications for understanding fundamental dream formation mechanisms but also for appreciating both the advantages and methodological pitfalls of conducting laboratory-based dream collection.

scholarly journals Identification of antibiotics in wastewater: current state of extraction protocol and future perspectives

2017 ◽  
Vol 15 (6) ◽  
pp. 982-1003 ◽  
Author(s):  
A. C. Faleye ◽  
A. A. Adegoke ◽  
K. Ramluckan ◽  
F. Bux ◽  
T. A. Stenström
Keyword(s):  
Solid Phase ◽  
Extraction Methods ◽  
Imprinted Polymer ◽  
Environmental Media ◽  
The Past ◽  
Current State ◽  
Liquid Liquid Extraction ◽  
Pros And Cons ◽  
Selection For ◽  
Near Future

AbstractThe release and occurrence of antibiotics in the aquatic environment has generated increased attention in the past few decades. The residual antibiotic in wastewater is important in the selection for antimicrobial resistance among microorganisms and the possibility of forming toxic derivatives. This review presents an assessment of the advancement in methods for extraction of antibiotics with solid phase extraction and liquid–liquid extraction methods applied in different aquatic environmental media. These advanced methods do enhance specificity, and also exhibit high accuracy and recovery. The aim of this review is to assess the pros and cons of the methods of extraction towards identification of quinolones and sulphonamides as examples of relevant antibiotics in wastewater. The challenges associated with the improvements are also examined with a view of providing potential perspectives for better extraction and identification protocols in the near future. From the context of this review, magnetic molecular imprinted polymer is superior over the remaining extraction methods (with the availability of commercial templates and monomers), is based on less cumbersome extraction procedures, uses less solvent and has the advantage of its reusable magnetic phase.

scholarly journals Fate of Neuraminidases of Influenza A Viruses

2020 ◽  
Vol 218 ◽  
pp. 03053
Author(s):  
Shaomin Yan ◽  
Guang Wu
Keyword(s):  
Influenza A ◽  
Large Scale ◽  
Small Scale ◽  
Influenza A Viruses ◽  
Simple Method ◽  
The Past ◽  
Current State ◽  
Pair Probability ◽  
History Of ◽  
Near Future

The current COVID-19 pandemic creates the biggest health and economic challenges to the world. However, not much knowledge is available about this coronavirus, SARS-CoV-2, because of its novelty. Indeed, it necessarily knows the fate of proteins generated by SARS-CoV-2. Anyway, before a large-scale study on proteins from SARS-CoV-2, it would be better to conduct a small-scale study on a well-known protein from influenza A viruses, because both are positive-sense RNA viruses. Thus, we applied a simple method of amino-acid pair probability to analyze 94 neuraminidases of influenza A viruses for better understanding of their fate. The results demonstrate three features of these neuraminidases: (i) the N1 neuraminidases are more susceptible to mutations, which is the current state of the neuraminidases; (ii) the N1 neuraminidases have undergone more mutations in the past, which is the history of the neuraminidases; and (iii) the N1 neuraminidases have a larger potential towards future mutations, which is the future of the neuraminidases. Moreover, our study reveals two clues on the mutation tendency, i.e. the mutations represent a degeneration process, and chickens, ducks and geese are rendered more susceptive to mutation. We hope to apply this approach to study the proteins from SARS-CoV-2 in near future.

scholarly journals Analysing recent augmented and virtual reality developments in tourism

2019 ◽  
Vol 10 (4) ◽  
pp. 571-586 ◽  
Author(s):  
Sérgio Moro ◽  
Paulo Rita ◽  
Pedro Ramos ◽  
Joaquim Esmerado
Keyword(s):  
Virtual Reality ◽  
Design Methodology ◽  
Secondary Data ◽  
Learning Approaches ◽  
Content Type ◽  
The Past ◽  
Large Sets ◽  
Current State ◽  
Near Future ◽  
Modelling Approach

Purpose Virtual reality (VR) and augmented reality (AR) are two technological breakthroughs that stimulate reality perception. Both have been applied in tourism contexts to improve tourists’ experience. This paper aims to frame both AR and VR developments during the past 15 years from a scientific perspective. Design/methodology/approach This study adopts a text mining and topic modelling approach to analyse a total of 1,049 articles for VR and 406 for AR. The papers were selected from Scopus, with the title, abstract and keywords being extracted for the analysis. Formulated research hypotheses based on relevant publications are then evaluated to assess the current state of the broader scope of the large sets of literature. Findings Most of research using AR is based on mobile technology. Yet, wearable devices still show few publications, a gap that is expected to close in the near future. There is a lack of research adopting Big Data/machine learning approaches based on secondary data. Originality/value As both AR and VR technologies are becoming more mature, more applications to tourism emerge. Scholars need to keep pace and fill in the research gaps on both domains to move research forward.

Current state and main directions of preservation and strengthening of health of the working population of Russia

2020 ◽  
pp. 527-532 ◽  
Author(s):  
I. V. Bukhtiyarov
Keyword(s):  
Working Conditions ◽  
Russian Federation ◽  
Production Environment ◽  
Working Population ◽  
Industrial Enterprises ◽  
The Past ◽  
Production Factors ◽  
Current State ◽  
The Russian Federation

The article presents the results of the analysis of health, working conditions and prevalence of adverse production factors, the structure of the detected occupational pathology in the working population of the Russian Federation. The article presents Statistical data on the dynamics of the share of workplaces of industrial enterprises that do not meet hygienic standards, occupational morbidity in 2015-2018 for the main groups of adverse factors of the production environment and the labor process. The indicators of occupational morbidity over the past 6 years in the context of the main types of economic activity, individual subjects of the Russian Federation, classes of working conditions, levels of specialized occupational health care. The role of the research Institute of occupational pathology and occupational pathology centers in solving organizational, methodological and practical tasks for the detection, treatment, rehabilitation and prevention of occupational diseases is shown. The basic directions of activity in the field of preservation and strengthening of health of workers, and also safety at a workplace are defined.

Phytochemical and Pharmacological Review on Two Herbs of Baijiangcao: Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss

2020 ◽  
Vol 17 (5) ◽  
pp. 496-517
Author(s):  
Yangcheng Liu ◽  
Wei Liu ◽  
Jiaqi Wang ◽  
Yang Liu ◽  
Changlan Chen ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Volatile Components ◽  
Research Papers ◽  
Pharmacological Activities ◽  
Comprehensive Review ◽  
Scientific Databases ◽  
The Past ◽  
Current State ◽  
Patrinia Scabiosaefolia ◽  
Antiviral Activities

Patrinia scabiosaefolia Fisch. Trev. and Patrinia villosa (Thunb.) Juss, are two species of Patrinia recorded in the Chinese Pharmacopoeia with the same Chinese name “Baijiangcao” and similar therapeutic effect in traditional Chinese medicine. The present article is the first comprehensive review on the chemical composition and pharmacological activities of these herbs. In this review, data on chemical constituents and pharmacological profile of the two herbs are provided. This review discusses all the classes of the 223 compounds (phenylpropanoids, flavonoids, terpenes, saponins and volatile components, etc.) detected in the two herbs providing information on the current state of knowledge of the phytochemicals present in them. In the past three years, our research group has isolated and identified about more than 100 ingredients from the two herbs. Therefore, we published a systematic review of our research papers and studies on the two herbs were carried out using resources such as classic books about Chinese herbal medicine and scientific databases including Pubmed, Web of Science, SciFinder, CNKI. etc. The present review discusses the most thoroughly studied pharmacological activities (antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, antitumor and antiviral activities) of the two herbs. This comprehensive review will be informative for scientists searching for new properties of these herbs and will be important and significant for the discovery of bioactive compounds from the two herbs and in complete utilization of Patrinia scabiosaefolia Fisch. ex Trev. and Patrinia villosa (Thunb.) Juss.

Understanding Molecular Process and Chemotherapeutics for the Management of Breast Cancer.

2020 ◽  
Vol 14 ◽  
Author(s):  
Abhishek Kumar ◽  
Neeraj Masand ◽  
Vaishali M. Patil
Keyword(s):  
Breast Cancer ◽  
Molecular Mechanisms ◽  
Molecular Targets ◽  
Molecular Classification ◽  
Neoplastic Disease ◽  
Molecular Process ◽  
The Past ◽  
Anti Cancer ◽  
Molecular Etiology ◽  
Near Future

Abstract: Breast cancer is the most common and highly heterogeneous neoplastic disease comprised of several subtypes with distinct molecular etiology and clinical behaviours. The mortality observed over the past few decades and the failure in eradicating the disease is due to the lack of specific etiology, molecular mechanisms involved in initiation and progression of breast cancer. Understanding of the molecular classes of breast cancer may also lead to new biological insights and eventually to better therapies. The promising therapeutic targets and novel anti-cancer approaches emerging from these molecular targets that could be applied clinically in the near future are being highlighted. In addition, this review discusses some of the details of current molecular classification and available chemotherapeutics

Movie Envy

2019 ◽  
pp. 70-80
Author(s):  
Olivier Asselin
Keyword(s):  
Point Of View ◽  
Digital Revolution ◽  
The Past ◽  
Current State ◽  
Movie Theatre ◽  
The Relationship

“Canadian cinema.” The term may appear self-evident but is problematic. First, one may question the value of national approaches to culture, especially here, in Quebec and Canada, where the debates over the Nation seem interminable, and especially now, in an era of globalization. Next, one may question the value of media-centered approaches to culture, especially when the successive waves of the “digital revolution” have blurred the boundaries between technologies and among artistic practices. Rather than try to survey “important” fiction films for theatres in Quebec or Canada, this essay adopts another point of view to examine the presence of cinema in Montreal museums over the past few years by focusing on three singular exhibitions. It may well be symptomatic of the current state of film in Quebec and Canada—but also, paradoxically, everywhere else—and says much about the relationship between medium and nation, the expansion of cinema beyond the movie theatre, and the internationalization of culture.

scholarly journals A decision model on the repair and maintenance of shipping containers

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Niclas Hoffmann ◽  
Robert Stahlbock ◽  
Stefan Voß
Keyword(s):  
Decision Model ◽  
Individual Decision ◽  
Microsoft Excel ◽  
Current State ◽  
Repair Costs ◽  
Transport Chain ◽  
Shipping Containers ◽  
Logistic Chain ◽  
Safe Transport ◽  
Near Future

Abstract The use of shipping containers for the transport of goods has become indispensable and a crucial factor for globalization by providing inexpensive and safe transport opportunities. It is expected that the number of globally operating containers will increase in the near future. Despite a high technical modernisation of the logistic chain, the container still faces a risk of damage at any time and any place within the transport chain. In principle, a container is taken out of service, when a damage is recognized. Different causes of damage exist and various types of damage could occur to the container, ranging from minor to substantial major ones that do not permit the continued proper use of the container. Thus, an individual decision on repair and maintenance (R&M) for each damaged container is necessary. Aside from technical aspects, it has to be decided from an economical perspective whether a repair should be performed. A profound decision should consider various criteria like, e.g., repair costs, lifespan of the container, future yields and possible sales price. Based on a regulatory, practical, and scientific view, this paper proposes a multi-criteria decision model for the economic decision on the R&M of a damaged container. Implemented in Microsoft Excel, this decision model is easily applicable. The user can deduce a first (limited) guidance for dealing with a respective damaged container based on its current state and general market conditions.

scholarly journals Multi-Task Optimization and Multi-Task Evolutionary Computation in the Past Five Years: A Brief Review

Mathematics ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 864
Author(s):  
Qingzheng Xu ◽  
Na Wang ◽  
Lei Wang ◽  
Wei Li ◽  
Qian Sun
Keyword(s):  
Evolutionary Computation ◽  
Explicit Knowledge ◽  
Optimization Problems ◽  
Effective Means ◽  
Typical Application ◽  
The Past ◽  
Current State ◽  
Evolution Algorithms ◽  
Application Fields

Traditional evolution algorithms tend to start the search from scratch. However, real-world problems seldom exist in isolation and humans effectively manage and execute multiple tasks at the same time. Inspired by this concept, the paradigm of multi-task evolutionary computation (MTEC) has recently emerged as an effective means of facilitating implicit or explicit knowledge transfer across optimization tasks, thereby potentially accelerating convergence and improving the quality of solutions for multi-task optimization problems. An increasing number of works have thus been proposed since 2016. The authors collect the abundant specialized literature related to this novel optimization paradigm that was published in the past five years. The quantity of papers, the nationality of authors, and the important professional publications are analyzed by a statistical method. As a survey on state-of-the-art of research on this topic, this review article covers basic concepts, theoretical foundation, basic implementation approaches of MTEC, related extension issues of MTEC, and typical application fields in science and engineering. In particular, several approaches of chromosome encoding and decoding, intro-population reproduction, inter-population reproduction, and evaluation and selection are reviewed when developing an effective MTEC algorithm. A number of open challenges to date, along with promising directions that can be undertaken to help move it forward in the future, are also discussed according to the current state. The principal purpose is to provide a comprehensive review and examination of MTEC for researchers in this community, as well as promote more practitioners working in the related fields to be involved in this fascinating territory.

Patents for Critical Pharmaceuticals: The AZT Case

1991 ◽  
Vol 17 (1-2) ◽  
pp. 145-180
Author(s):  
Evan Ackiron
Keyword(s):  
The United States ◽  
Incentive System ◽  
The Public ◽  
Incentive Programs ◽  
The Past ◽  
Research And Innovation ◽  
Monopoly Pricing ◽  
Conflicting Interests ◽  
Necessary Evil ◽  
Near Future

Patents and other statutory types of market protections are used in the United States to promote scientific research and innovation. This incentive is especially important in research intensive fields such as the pharmaceutical industry. Unfortunately, these same protections often result in higher monopoly pricing once a successful product is brought to market. Usually this consequence is viewed as the necessary evil of an incentive system that encourages costly research and development by promising large rewards to the successful inventor. However, in the case of the AIDS drug Zidovudine (AZT), the high prices charged by the pharmaceutical company owning the drug have led to public outcry and a re-examination of government incentive systems.This Note traces the evolution of these incentive programs — the patent system, and, to a lesser extent, the orphan drug program — and details the conflicting interests involved in their development. It then demonstrates how the AZT problem brings the interest of providing inventors with incentives for risky innovative efforts into a sharp collision with the ultimate goal of such systems: ensuring that the public has access to the resulting products at a reasonable price. Finally, the Note describes how Congress and the courts have attempted to resolve these problems in the past, and how they might best try to solve the AZT problem in the near future.

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