scholarly journals Persistent eczema leads to both impaired growth and food allergy: JECS birth cohort

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0260447
Author(s):  
Kiwako Yamamoto-Hanada ◽  
Yuichi Suzuki ◽  
Limin Yang ◽  
Mayako Saito-Abe ◽  
Miori Sato ◽  
...  
Keyword(s):  
Food Allergy ◽  
Birth Cohort ◽  
Early Onset ◽  
Linear Models ◽  
Disease Onset ◽  
Skin Inflammation ◽  
Physical Growth ◽  
Birth Cohort Study ◽  
Chemokine Production ◽  
The Relationship

Skin inflammation leads to altered cytokine/chemokine production and causes systemic inflammation. The systemic mechanism of atopic dermatitis (AD) is recognized to affect systemic metabolism. This study aimed to examine the relationship between early-onset persistent eczema and body weight, height, and body mass index (BMI), in addition to food allergy in a birth cohort among infants. This study design was a nationwide, multicenter, prospective birth cohort study—the Japan Environment and Children’s Study (JECS). Generalized linear models were fitted for z scores of weight, height, BMI, and food allergy to evaluate the relationship between eczema and these outcomes for infants at age1, 2, and 3 years. Persistent eczema was negatively associated with height at the age of 2 years (estimated coefficient, −0.127; 95% confidence interval [CI], −0.16 to −0.095) and 3 years (−0.177; 95% CI, −0.214 to −0.139). The same tendency was also observed with weight and BMI. Early disease onset at younger than 1 year and persistent eczema had the strongest association with development of food allergy at age 3 years (OR, 11.794; 95% CI, 10.721–12.975). One phenotype of eczema with early-onset and persistent disease creates a risk of both physical growth impairment and development of food allergy. Infants who present with the early-onset and persistent type of eczema should be carefully evaluated daily for impaired physical growth and development of food allergy.

scholarly journals The ADAPAR Birth Cohort Study: Food Allergy Results at Five Years and New Insights

2016 ◽  
Vol 169 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Dilek Doğruel ◽  
Gülbin Bingöl ◽  
Mustafa Yılmaz ◽  
Derya Ufuk Altıntaş
Keyword(s):  
Cohort Study ◽  
Food Allergy ◽  
Birth Cohort ◽  
Birth Cohort Study

Antenatal vitamin D exposure and childhood eczema, food allergy, asthma and allergic rhinitis at 2 and 5 years of age in the atopic disease-specific Cork BASELINE Birth Cohort Study

Allergy ◽  
2018 ◽  
Vol 73 (11) ◽  
pp. 2182-2191 ◽  
Author(s):  
Áine Hennessy ◽  
Jonathan O'B Hourihane ◽  
Lucio Malvisi ◽  
Alan D. Irvine ◽  
Louise C. Kenny ◽  
...  
Keyword(s):  
Vitamin D ◽  
Allergic Rhinitis ◽  
Cohort Study ◽  
Food Allergy ◽  
Birth Cohort ◽  
Atopic Disease ◽  
Birth Cohort Study ◽  
Disease Specific

scholarly journals Associations between developmental timing of child abuse and conduct problem trajectories in a UK birth cohort

2020 ◽  
Author(s):  
Andreas Bauer ◽  
Gemma Hammerton ◽  
Abigail Fraser ◽  
Graeme Fairchild ◽  
Sarah L. Halligan
Keyword(s):  
Child Abuse ◽  
Birth Cohort ◽  
Conduct Problems ◽  
Early Onset ◽  
Latent Class ◽  
Developmental Stages ◽  
Developmental Trajectories ◽  
Conduct Problem ◽  
Self Report ◽  
Birth Cohort Study

Abstract Background Although there is strong evidence for a relationship between child abuse and neglect and conduct problems, associations between child abuse experienced at different developmental stages and developmental trajectories of conduct problems have not been examined. We sought to investigate effects of timing of child abuse on conduct problem trajectories in a large UK birth cohort study. Methods We applied latent class growth analysis to identify conduct problem trajectories in the Avon Longitudinal Study of Parents and Children, using parent-rated conduct problems from ages 4-17 years (N=10648). Childhood-only and adolescence-only abuse, in addition to abuse in both developmental periods (‘persistent’ abuse), were assessed by retrospective self-report at age 22 years (N=3172). Results We identified four developmental trajectories: early-onset persistent (4.8%), adolescence-onset (4.5%), childhood-limited (15.4%), and low (75.3%) conduct problems. Childhood-only abuse and ‘persistent’ abuse were associated with increased odds of being on the early-onset persistent and adolescence-onset conduct problem trajectories compared to the low conduct problems trajectory. Adolescence-only abuse was not predictive of trajectory membership. There were no associations between abuse and childhood-limited trajectory membership.Conclusions Early-onset persistent and adolescence-onset conduct problems showed similar patterns of association with abuse exposure, challenging developmental theories that propose qualitative, as opposed to quantitative, differences in environmental risk factors between these trajectories. The results also highlight that childhood-only and ‘persistent’ abuse were more strongly linked to elevated conduct problem trajectories than adolescence-only abuse, and that ‘persistent’ abuse is particularly detrimental.

Does IQ Influence Association Between Working Memory and ADHD Symptoms in Young Adults?

2021 ◽  
pp. 108705472110588
Author(s):  
Pedro San Martin Soares ◽  
Paula Duarte de Oliveira ◽  
Fernando César Wehrmeister ◽  
Ana Maria Baptista Menezes ◽  
Luis Augusto Rohde ◽  
...  
Keyword(s):  
Working Memory ◽  
Young Adults ◽  
Cohort Study ◽  
Birth Cohort ◽  
Poisson Regression ◽  
Birth Cohort Study ◽  
Adhd Symptoms ◽  
Negatively Associated ◽  
Robust Variance ◽  
The Relationship

Objective This study examined the association between WM and ADHD symptoms in young adults and whether IQ-score influenced this association. Method Data from the 1993 Pelotas (Brazil) Birth Cohort Study were analyzed ( N = 2,845). Working memory and ADHD symptoms were collected at 22 years. IQ was examined at age 18. Poisson regression with robust variance was used to assess the associations between working memory and ADHD symptoms. We also evaluated whether IQ modified associations between working memory and ADHD symptoms. Results Working memory was negatively associated with Inattention symptoms of ADHD. The association between working memory and hyperactivity-impulsivity symptoms of ADHD varied by IQ. Conclusions This study provides new insights to theories about the relationship between WM and ADHD symptoms as well as the development of interventions aimed at improving the performance of WM in ADHD.

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