scholarly journals Clinical spectrum of endemic leptospirosis in relation to cytokine response

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0261025
Author(s):  
Niroshana J. Dahanayaka ◽  
Suneth B. Agampodi ◽  
Indika Seneviratna ◽  
Janith Warnasekara ◽  
Rukman Rajapakse ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Kidney Injury ◽  
Magnetic Bead ◽  
High Serum ◽  
Cytokine Response ◽  
Clinical Spectrum ◽  
University Teaching ◽  
Prognostic Information ◽  
Gm Csf ◽  
The University

Objectives To describe the clinical spectrum and the cytokine response of leptospirosis patients in an endemic setting of Sri Lanka. Methods Patients presenting to the university teaching hospital, Anuradhapura, Sri Lanka with a leptospirosis-compatible illness were recruited over a period of 12 months starting from June 2012. Daily clinical and biochemical parameters of the patients were prospectively assessed with a follow-up of 14 days after discharge. A magnetic bead–based multiplex cytokine kit was used to detect 17 cytokines. Results Of the 142 clinically suspected leptospirosis patients recruited, 47 were confirmed and, 29 cases were labeled as “probable.” Thrombocytopenia and leukocytosis were observed at least once during the hospital stay among 76(54%) and 39(28%) patients, respectively. Acute kidney injury was observed in 31 patients (22%) and it was significantly higher among confirmed and probable cases. Hu TNF-α and IL-1β were detected only in patients without complications. Hu MIP-1b levels were significantly higher among patients with complications. During the convalescence period, all tested serum cytokine levels were lower compared to the acute sample, except for IL-8. The cytokine response during the acute phase clustered in four different groups. High serum creatinine was associated GM-CSF, high IL-5 and IL-6 level were correlates with lung involvement and saturation drop. The patients with high billirubin (direct)>7 mmol/l had high IL-13 levels. Conclusions Results of this study confirms that the knowledge on cytokine response in leptospirosis could be more complex than other similar tropical disease, and biosignatures that provide diagnostic and prognostic information for human leptospirosis remain to be discovered.

Educational text in the aspect of intellectualization of the university teaching of the russian language

2019 ◽  
Author(s):  
Karina Amaiakovna Oganesian
Keyword(s):  
Literary Text ◽  
Educational Process ◽  
Russian Language ◽  
University Teaching ◽  
Motivational Level ◽  
Linguistic Aspect ◽  
The University ◽  
The Russian Language

The article discusses the issue of intellectualizing the process of learning a language through the prism of studying literary text, describes the multiplicity of approaches and directions in studying an artistic text in order to reveal its nature in the linguistic aspect, increase the motivational level and update the educational process.

Visión social de la estrategia de formación de la competencia investigativa en el profesor universitario

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Concepción Elizabeth Marcillo García
Keyword(s):  
World Economy ◽  
Research University ◽  
University Teaching ◽  
Social Approach ◽  
University Teachers ◽  
Research Competence ◽  
Research Fields ◽  
University Professor ◽  
Relevant Topic ◽  
The University

El momento que viven las universidades ecuatorianas, se caracteriza por la búsqueda de una mejora significativa en el campo académico, investigativo y de vinculación con la comunidad. La intervención de algunas universidades por parte del CES, ha sido una medida que se constituye en oportunidad para lograr cubrir las expectativas de la sociedad y de las instancias superiores encargadas de velar por el desarrollo de la Academia. Las deficiencias encontradas develaron las causas principales que aquejan a estas comunidades: el pobre desarrollo de la investigación. En este marco, el presente trabajo se constituye en un tema pertinente, al proyectar una propuesta que se sustenta en la necesidad de formación de la docencia universitaria en el ámbito de la investigación. El análisis que se realiza a la propuesta, tiene un enfoque social pensado en función del servicio que presta la Universidad a la colectividad en aras de responder a la sociedad que concomitante al progreso mundial, apuntala su economía en el desarrollo del conocimiento. Considerar una estrategia para el desarrollo de las competencias investigativas en los docentes universitarios, ayudará a fortalecer la función investigativa, consecuentemente, se generará y crearán condiciones que permitan transferir tecnologías tendientes a mejorar las condiciones de vida del sector.  Palabras claves: Docencia universitaria, competencia investigativa, investigación, universidad, estrategia  Social view of the strategy for the formation of the research competence in the university professor    Abstract  The Ecuadorian universities are changing today and that is characterized by the search for a significant improvement in the academic and research fields and the link with the community. The intervention of some universities by the CES has been a measure which constitutes an opportunity to meet the society’s expectations and those of the higher level authorities to ensure the development of the university. The deficiencies found uncovered the main causes affecting these communities: the poor development of research. In this context, the present work constitutes a relevant topic, to project a proposal that is based on the need for training in the field of researching the university teachers. The analysis of the proposal has a social approach, which functions through the service provided by the University to the community in order to respond to the global society concomitant progress that seeks the development of knowledge while developing the world economy. To consider a strategy for the researching competence development in university teachers will help strengthening the researching function. Consequently, it will generate and create conditions for transferring technologies aimed at improving the living conditions of the teachers.  Keywords: University teaching, research competence, research, university, strategy

Location and Size of Coronary Ostia in Normal Autopsied Hearts at the University Teaching Hospital, Lusaka, Zambia

2016 ◽  
Vol 3 (4) ◽  
pp. 199-203 ◽  
Author(s):  
Moono Silitongo ◽  
◽  
Dailesi Ndlovu ◽  
Kasonde Bowa ◽  
Krikor Erzingatsian ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
University Teaching ◽  
Coronary Ostia ◽  
The University

scholarly journals Analysis of Stress Factors for Female Professors at Online Universities

2020 ◽  
Vol 17 (8) ◽  
pp. 2958 ◽  
Author(s):  
Marialuz Arántzazu García-González ◽  
Fermín Torrano ◽  
Guillermo García-González
Keyword(s):  
Risk Factors ◽  
Time Pressure ◽  
Health And Safety ◽  
Stress Factors ◽  
University Teaching ◽  
Psychosocial Risks ◽  
Primary Stress ◽  
Information And Communication ◽  
The University ◽  
Mental Overload

The aim of this paper is to analyze the primary stress factors female professors at online universities are exposed to. The technique used for the prospective and exploratory analysis was the Delphi method. Two rounds of consultations were done with fourteen judges with broad experience in health and safety at work and university teaching who reached a consensus of opinion regarding a list of nine psychosocial risk factors. Among the most important risk factors, mental overload, time pressure, the lack of a schedule, and emotional exhaustion were highlighted. These risk factors are related to the usage and expansion of information and communication technology (ICT) and to the university system itself, which requires initiating more research in the future in order to develop the intervention programs needed to fortify the health of the affected teachers and protect them from stress and other psychosocial risks.

Berufsfelder und -chancen von Wirtschaftsgeographen

2013 ◽  
Vol 57 (1-2) ◽  
Author(s):  
Rolf Sternberg
Keyword(s):  
Economic Geography ◽  
Work Conditions ◽  
University Education ◽  
University Teaching ◽  
Follow Up Study ◽  
Career Opportunities ◽  
Close Relationship ◽  
The University ◽  
Good Career

Occupational fields and career prospects of economic geographers. Empirical evidence from a graduate follow-up study at the Leibniz Universität Hannover and conclusions for teaching at universities. The employability of the alumni has become an important aspect of university teaching in Germany since bachelor and master courses were introduced some years ago. This also applies for the university education of economic geographers. The paper demonstrates the increased and still increasing relevance of employability for economic geographers studying at German universities. Based on data for 295 economic geography graduates from the Leibniz Universität Hannover it is shown that such alumni have rather good career opportunities to achieve both high income and satisfying work conditions. Adequate specialization of the curriculum, excellence in teaching and research, and a close relationship between university teaching (and teachers) and the professional world outside the university are important conditions for successful alumni.

Project-Oriented Learning as an Optimal Methodology for the Incorporation of the SDGs in University Teaching: A Systematic Review

2021 ◽  
Author(s):  
Antonio Miñán-Espigares ◽  
Claudia-Amanda Juárez-Romero
Keyword(s):  
Systematic Review ◽  
Sustainable Development ◽  
Situated Learning ◽  
Sustainable Development Goals ◽  
University Teaching ◽  
Teaching Innovation ◽  
The Sustainable Development ◽  
Development Goals ◽  
The University ◽  
Quality Learning

The use of active methodologies in the university is a priority to achieve higher quality learning. One of these methodologies with the greatest potential for training in competencies is Project-Oriented Learning (PLA), using it in an innovative way. Associating the use of this methodology with the objectives of sustainable development, which have become even more important since the Pandemic by COVID-19, can be a good idea to achieve a more sustained and situated learning. The aim of this study is to find out to what extent research on teaching innovation with Project-Oriented Learning is associated with the Sustainable Development Goals. A systematic review was carried out as indicated by PRISMA through the following databases: WOS and Scopus. WOS found 15 articles on AoP and 6 on Project-Oriented Learning and sustainability. In Scopus 2 were found in 2019. The main results show that in the University, especially in the branches of engineering, AoP is widely used, however, it is rarely related to SDGs. Among the conclusions, we highlight the need for research on project-oriented learning and sustainable development goals.

Comparison of Static and Dynamic Baseline Creatinine Surrogates for Defining Acute Kidney Injury

Nephron ◽  
2021 ◽  
pp. 1-11
Author(s):  
David G. Warnock ◽  
Javier A. Neyra ◽  
Etienne Macedo ◽  
Ayme D. Miles ◽  
Ravindra L. Mehta ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Day Length ◽  
University Of Alabama ◽  
Inpatient Mortality ◽  
Baseline Serum ◽  
Net Reclassification Improvement ◽  
Baseline Creatinine ◽  
The University ◽  
Final Cohort

<b><i>Background:</i></b> “Dynamic” baseline serum creatinine (sCr), based on a rolling 48-h window, and a static baseline sCr (previous outpatient sCr) were used to define acute kidney injury (AKI). <b><i>Methods:</i></b> Retrospective cohort study of adult admissions to the University of Alabama (UAB) Health System hospitals for years 2016–2018. Included admissions had &#x3e;1- and &#x3c;180-day length of stay, &#x3e;2 inpatient sCr measurements, and an averaged estimated glomerular filtration rate &#x3e;15 mL/min/1.73 m<sup>2</sup>. The final cohort of 62,380 patients included 100,570 admissions, 3,509 inpatient deaths, and 1,916 admissions with inpatient dialysis. AKI was defined by Kidney Disease Improving Global Outcomes (KDIGO) criteria and a static or dynamic baseline sCr. Discrimination was evaluated with area under receiver operator curves (AUC), logistic regression, and net reclassification improvement (NRI). <b><i>Results:</i></b> Preadmission outpatient “static” sCr values were available for 43,433 admissions. The lowest sCr value during a rolling 48-h window before each inpatient sCr defined a “dynamic” baseline sCr. Using point-wise comparisons, the dynamic baseline sCr performed better than static baseline sCr for inpatient mortality (AUC [0.819 vs. 0.741; <i>p</i> &#x3c; 0.001] and NRI ≥0.306 [<i>p</i> &#x3c; 0.001]) and inpatient dialysis (AUC [0.903 vs. 0.864; <i>p</i> &#x3c; 0.001] and NRI ≥0.317 [<i>p</i> &#x3c; 0.001]). <b><i>Conclusions:</i></b> The dynamic baseline sCr is available without reference to preadmission sCr values and avoids confounding associated with missing outpatient sCr values. AKI defined with the dynamic baseline sCr significantly improved discrimination of risk for inpatient mortality and dialysis compared to static baseline sCr.

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