scholarly journals A comprehensive review on green synthesis of titanium dioxide nanoparticles and their diverse biomedical applications

2022 ◽  
Vol 11 (1) ◽  
pp. 44-63
Author(s):  
Suresh Sagadevan ◽  
Shahla Imteyaz ◽  
Baranya Murugan ◽  
Jayasingh Anita Lett ◽  
Nanthini Sridewi ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Titanium Dioxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Cost Effective ◽  
Biological Synthesis ◽  
Synthesis Methods ◽  
Environmental Friendliness ◽  
Environmentally Safe

Abstract Metal oxide nanoparticles (NPs) have found a variety of applications in numerous industrial, medical, and environmental fields s, attributable to recent advances in the nanotechnology field. Titanium dioxide nanoparticles (TiO2-NPs) have gained importance as metal oxide NPs due to their potential in various fields, particularly nanomedicine and other biomedicine fields. Several studies have confirmed that NPs produced via the biosynthesis route using natural resources have significant advantages such as fewer toxic contaminants, less subsequent complex chemical synthesis, environmental friendliness, cost-effectiveness, and stability when compared to NPs produced by conventional methods, and its production with controlled shapes and sizes. Therefore, considerable effort is being expended to implement biological synthesis methods with these proven advantages. TiO2-NPs can be made using a variety of biological, chemical, and physical methods. Physicochemical methods are costly, emit high levels of toxic chemicals into the atmosphere, and consume a lot of energy. On the other hand, the biological approach is an environmentally safe, cost-effective, dependable, convenient, and easy way to synthesize TiO2-NPs. In this review, the bio-mediated synthesis, as well as various biomedical applications of TiO2-NPs, were discussed.

A Review on Antimicrobial Properties of Metal Nanoparticles

2020 ◽  
Vol 20 (6) ◽  
pp. 3303-3339 ◽  
Author(s):  
Saee Gharpure ◽  
Aman Akash ◽  
Balaprasad Ankamwar
Keyword(s):  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Antimicrobial Agents ◽  
Metal Oxide Nanoparticles ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Micro Organisms

The field of nanotechnology elaborates the synthesis, characterization as well as application of nanomaterials. Applications of nanoparticles in various fields have interested scientists since decades due to its unique properties. Combination of pharmacology with nanotechnology has helped in development of newer antimicrobial agents in order to control the ever increasing multidrug resistant micro-organisms. Properties of metal and metal oxide nanoparticles like silver, gold, titanium dioxide as well as magnesium oxide as antimicrobial agents are very well known. This review elaborates synthesis methods and antimicrobial mechanisms of various metal as well as metal oxide nanoparticles for better understanding in order to utilize their potentials in various biomedical applications.

A comparative study of metal oxide nanoparticles embryotoxicity using the embryonic stem cell test

2013 ◽  
Vol 14 (1-2) ◽  
pp. 61-64 ◽  
Author(s):  
Lucia Vecchione ◽  
Micol Massimiani ◽  
Antonella Camaioni ◽  
Luna Sifrani ◽  
Andrea Magrini ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Titanium Dioxide ◽  
Metal Oxide ◽  
Biomedical Applications ◽  
Titanium Dioxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Embryonic Stem ◽  
Oxide Nanoparticles ◽  
Cell Test

AbstractMany in vitro studies demonstrated that metal oxide nanoparticles like zinc oxide and titanium dioxide are versatile platforms for industrial and biomedical applications. In this paper, investigation of the embryotoxic potential of these nanoparticles using the Embryonic stem Cells Test (EST) was evaluated. The EST is a validated in vitro toxicity test used to predict embryotoxicity of soluble chemical compounds, which only recently has been applied to nanoparticles, demonstrating its suitability also in nanotoxicology. Through such test, we were able to classify zinc oxide nanoparticles as not embryotoxic, while titanium dioxide nanoparticles appeared to be weakly embryotoxic.

scholarly journals Biosynthesis, Antimicrobial and Cytotoxic Effects of Titanium Dioxide Nanoparticles Using Vigna unguiculata Seeds

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Ankita Chatterjee ◽  
M. Ajantha ◽  
Aishwarya Talekar ◽  
N. Revathyr ◽  
Jayanthi Abraham
Keyword(s):  
Titanium Dioxide ◽  
Metal Nanoparticles ◽  
Vigna Unguiculata ◽  
Titanium Dioxide Nanoparticles ◽  
Cost Effective ◽  
Biological Synthesis ◽  
Osteosarcoma Cell ◽  
Cowpea Seeds ◽  
Clinical Pathogens ◽  
Physical And Chemical

Background: Physical and chemical methods of synthesizing metal nanoparticles have been on the focus for the last decade as it has been broadly exploited by researchers. Biological synthesis of metal nanoparticles was found to be easy and economical. The wide applications of titanium dioxide in various fields have drawn attention for biosynthesis of titanium dioxide nanoparticles. Cowpea seeds are easily available and rich in protein as well as high in antioxidant which enhances the good characteristics of the nanoparticles synthesized using it. Methods: In the present investigation the nanoparticles are synthesized using Vigna unguiculata (cowpea) seeds extract. 0.1 mM titanium dioxide was mixed with cowpea seeds extract for the preparation of the nanoparticles. The characterization of nanoparticles was done by Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). Antibacterial activity of the titanium dioxide nanoparticles was checked against clinical pathogens followed by antioxidant study and cytotoxicity assay by 2, 2- diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assay and [3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide] (MTT) assay respectively. Results: The oval shaped biologically synthesized nanoparticles were effective against most of the clinical pathogens. The observance of peak at 418 cm-1 confirms the synthesis of titanium dioxide nanoparticles. The titanium nanoparticles were highly antioxidant in nature and cytotoxic on MG63 osteosarcoma cell lines. Conclusion: The biological method of preparation of nanoparticles proved to be easy and cost effective. The nanoparticles synthesized can be further used in research for anticancer treatments

Green Synthesis of Nanomaterials Using Plant Extract: A Review

2020 ◽  
Vol 21 ◽  
Author(s):  
Amol Nande ◽  
Swati Raut ◽  
Marta Michalska-Domanska ◽  
S. J. Dhoble
Keyword(s):  
Metal Oxide ◽  
Plant Extracts ◽  
Animal Health ◽  
Metal Oxide Nanoparticles ◽  
Cost Effective ◽  
Synthesis Process ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Synthesis Mechanism ◽  
Pass Through

: From last two decades, extensive research is going on metal and metal oxide nanoparticles and their application in field of medical, cosmetic, catalyst, packaging, photonics, agriculture and electronics. However, these nanoparticles show toxicity to the environmental, human and animal health. The toxicity effects of nanoparticles are mainly due to its size which can be easily pass through physiological barriers and the other due to the synthesis procedure. The toxicity due to their size cannot be avoided but toxicity due to synthesis process can be nullified by adopting biosynthesis process. Bacteria, fungus, fish scales, plant extracts and algae are used to synthesize metal and metal-oxide nanoparticles such as silver, gold, iron-oxide, zinc-oxide, zirconia, etc. From last a few year researchers are working on plant extracts synthesis methods to produce stable, cost-effective and economical these nanoparticles. In this review, we focus on biosynthesis of nanoparticles using different parts of plant extracts. The review contains summary of selected papers from 2018 – 20 with detail description of process of synthesis, mechanism, characterization and their application in various fields of biosynthesized metal and metal oxide nanoparticles.

scholarly journals Nanocellulose Hybrids with Metal Oxides Nanoparticles for Biomedical Applications

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4045 ◽  
Author(s):  
Madalina Oprea ◽  
Denis Mihaela Panaitescu
Keyword(s):  
Metal Oxide ◽  
Metal Oxides ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Ex Situ ◽  
Current Status ◽  
Polymer Support ◽  
Synthesis Methods ◽  
Preparation Methods

Cellulose is one of the most affordable, sustainable and renewable resources, and has attracted much attention especially in the form of nanocellulose. Bacterial cellulose, cellulose nanocrystals or nanofibers may serve as a polymer support to enhance the effectiveness of metal nanoparticles. The resultant hybrids are valuable materials for biomedical applications due to the novel optical, electronic, magnetic and antibacterial properties. In the present review, the preparation methods, properties and application of nanocellulose hybrids with different metal oxides nanoparticles such as zinc oxide, titanium dioxide, copper oxide, magnesium oxide or magnetite are thoroughly discussed. Nanocellulose-metal oxides antibacterial formulations are preferred to antibiotics due to the lack of microbial resistance, which is the main cause for the antibiotics failure to cure infections. Metal oxide nanoparticles may be separately synthesized and added to nanocellulose (ex situ processes) or they can be synthesized using nanocellulose as a template (in situ processes). In the latter case, the precursor is trapped inside the nanocellulose network and then reduced to the metal oxide. The influence of the synthesis methods and conditions on the thermal and mechanical properties, along with the bactericidal and cytotoxicity responses of nanocellulose-metal oxides hybrids were mainly analyzed in this review. The current status of research in the field and future perspectives were also signaled.

scholarly journals Metal Oxide Nanoparticles and their Nanocomposite-based Materials as Photocatalysts in the Degradation of Dyes

2021 ◽  
Vol 12 (5) ◽  
pp. 6557-6579
Keyword(s):  
Metal Oxide ◽  
Anthropogenic Activities ◽  
Metal Oxide Nanoparticles ◽  
Chemical Properties ◽  
Cost Effective ◽  
Oxide Nanoparticles ◽  
Synthetic Dyes ◽  
Characterization Methods ◽  
Degradation Of Dyes ◽  
Physical And Chemical

The introduction of inorganic and organic pollutants into water bodies has become a serious issue globally. The waste streams released from the textile, plastic, leather, paper, pharmaceutical, and food industries introduce different natural and synthetic dyes into the aquatic system. Nanomaterials play a significant role in the photocatalytic degradation of dyes present in wastewater. Inorganic metal oxide nanoparticles have many improved physical and chemical properties and attracted much attention in photocatalytic activities. Dyes have been released in our aquatic bodies due to many anthropogenic activities and caused life-threatening problems. Various conventional methods were reported to remove dyes from water and wastewater; the photocatalytic method is one of the efficient and cost-effective. The present review article includes detailed information on photocatalysis, the potential of metal oxide and their composite materials as photocatalysts in the degradation of toxic dyes, and some common synthetic and characterization methods used for metal oxide-based nanoparticles.

Surface coating and functionalization of metal and metal oxide nanoparticles for biomedical applications

2022 ◽  
pp. 205-231
Author(s):  
Raj Kumar ◽  
Guruprasad Reddy Pulikanti ◽  
Konathala Ravi Shankar ◽  
Darsi Rambabu ◽  
Venkateswarulu Mangili ◽  
...  
Keyword(s):  
Metal Oxide ◽  
Surface Coating ◽  
Biomedical Applications ◽  
Metal Oxide Nanoparticles ◽  
Oxide Nanoparticles

Synthesis of Silver Nanoparticles and their Biomedical Applications - A Comprehensive Review

2019 ◽  
Vol 25 (24) ◽  
pp. 2650-2660 ◽  
Author(s):  
Rajasree Shanmuganathan ◽  
Indira Karuppusamy ◽  
Muthupandian Saravanan ◽  
Harshiny Muthukumar ◽  
Kumar Ponnuchamy ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Biomedical Applications ◽  
Antibacterial Agents ◽  
Cost Effective ◽  
Metallic Silver ◽  
Synthesis Methods ◽  
Burn Wound ◽  
Chemical Methods ◽  
Biological Sources ◽  
Physical And Chemical

Generally, silver is considered as a noble metal used for treating burn wound infections, open wounds and cuts. However, the emerging nanotechnology has made a remarkable impact by converting metallic silver into silver nanoparticles (AgNPs) for better applications. The advancement in technology has improved the synthesis of NPs using biological method instead of physical and chemical methods. Nonetheless, synthesizing AgNPs using biological sources is ecofriendly and cost effective. Till date, AgNPs are widely used as antibacterial agents; therefore, a novel idea is needed for the successful use of AgNPs as therapeutic agents to uncertain diseases and infections. In biomedicine, AgNPs possess significant advantages due to their physical and chemical versatility. Indeed, the toxicity concerns regarding AgNPs have created the need for non-toxic and ecofriendly approaches to produce AgNPs. The applications of AgNPs in nanogels, nanosolutions, silver based dressings and coating over medical devices are under progress. Still, an improvised version of AgNPs for extended applications in an ecofriendly manner is the need of the hour. Therefore, the present review emphasizes the synthesis methods, modes of action under dissipative conditions and the various biomedical applications of AgNPs in detail.

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