[(Methoxythio)carbonyl]pyridin-Derivate, eine neue Verbindungsklasse aus Pseudomonas putida [1] / [(M ethoxythio)carbonyl]pyridine Derivatives, a New Class of Compounds from Pseudomonas putida [1]

1985 ◽  
Vol 40 (11) ◽  
pp. 1563-1565 ◽  
Author(s):  
U. Hildebrand ◽  
K. Taraz ◽  
H. Budzikiewicz
Keyword(s):  
Pseudomonas Putida ◽  
Structure Elucidation ◽  
Culture Medium ◽  
Pyridine Derivatives ◽  
New Class

From the culture medium of Pseudomonas putida three pyridine derivatives were isolated which contain the (methoxythio)carbonyl (CO−S-OCH3) group thus far not described in the literature. Characterization and structure elucidation are reported.

Weitere aus dem Kulturmedium von Pseudomonas putida isolierte Pyridinderivate -Genuine Metaboliten oder Artefakte ?/Further Pyridine Derivatives Isolated from the Culture Medium of Pseudomonas putida - Genuine Metabolites or Artefacts ?

1983 ◽  
Vol 38 (4) ◽  
pp. 516-520 ◽  
Author(s):  
H. Budzikiewicz ◽  
U. Hildebrand ◽  
W. Ockels ◽  
M. Reiche ◽  
K. Taraz
Keyword(s):  
Methyl Ester ◽  
Pseudomonas Putida ◽  
Culture Medium ◽  
Pyridine Derivatives

Abstract From the culture medium of Pseudomonas putida after treatment with CH2N2 besides the expected Pyridine-2,6-di(monothiocarboxylic acid)-di-S-methyl ester a series of pyridine derivatives could be isolated which could be shown to be artefacts formed from pyridine-2,6-di(monothiocarboxylic acid).

Thieno[2,3-b]pyridine derivatives: a new class of antiviral drugs against Mayaro virus

2017 ◽  
Vol 162 (6) ◽  
pp. 1577-1587 ◽  
Author(s):  
Raquel Amorim ◽  
Marcelo Damião Ferreira de Meneses ◽  
Julio Cesar Borges ◽  
Luiz Carlos da Silva Pinheiro ◽  
Lucio Ayres Caldas ◽  
...  
Keyword(s):  
Antiviral Drugs ◽  
Pyridine Derivatives ◽  
New Class ◽  
Mayaro Virus

2,3,9-Trihydroxyphenazin-l-carbonsäure – ein unter Berylliumeinwirkung gebildetes neues Phenazinderivat aus Pseudomonas fluorescens [1] / 2,3,9-Trihydroxyphenazine- l -carboxylic Acid — a New Phenazine Derivative from Pseudomonas fluorescens Grown under Beryllium Stress [1]

1990 ◽  
Vol 45 (4) ◽  
pp. 552-556 ◽  
Author(s):  
K. Taraz ◽  
E. M. Schaffner ◽  
H. Budzikiewicz ◽  
H. Korth ◽  
G. Pulverer
Keyword(s):  
Carboxylic Acid ◽  
Iron Deficiency ◽  
Dicarboxylic Acid ◽  
Pseudomonas Fluorescens ◽  
Structure Elucidation ◽  
Culture Medium ◽  
Phenazine Derivative

In addition to phenazine, phenazine-1-carboxylic acid, phenazine-1,6-dicarboxylic acid and 2,9-dihydroxyphenazine-1-carboxylic acid a new compound, viz. 2,3,9-trihydroxyphenazine-1-carboxylic acid could be isolated from the culture medium of Pseudomonas fluorescens grown under iron deficiency with beryllium added to the culture medium. Its structure elucidation is described.

Structure Elucidation of Azotobactin 87, Isolated from Azotobacter vinelandii ATCC 12837*, **

1996 ◽  
Vol 51 (3-4) ◽  
pp. 139-150 ◽  
Author(s):  
E. M. Schaffner ◽  
R. Hartmann ◽  
K. Taraz ◽  
H. Budzikiewicz
Keyword(s):  
Structure Elucidation ◽  
Culture Medium ◽  
Azotobacter Vinelandii ◽  
2D Nmr ◽  
Chemical Degradation ◽  
Spectroscopic Methods ◽  
Hydroxybutyric Acid ◽  
Iron Deficient ◽  
N Terminus ◽  
Sequential Information

Abstract Chromopeptide siderophores (azotobactin 87-1 and -II) were isolated from an iron deficient culture medium of Azotobacter vinelandii ATCC 12837 (=DSM 87). Their structures were elu­ cidated by chemical degradation studies and spectroscopic methods, especially 2D-NMR-tech-niques. Total assignments of 1H-, 13C-, and 15N-resonances based on 2D-HOHAHA-, 1H/13C-HMQC-, 1H /13C-HMBC-, 1H /15N-HMQC/TOCSY-, and 1H/15N-HMBC-experiments are given as well as sequential information derived from 1H/1H-NOESY-, 1H /13C-HMBC-and 1H/ 13N-HMBC-experiments. Both Az 87-1 and Az 87-11 consist of a tetracyclic chromophore -(1S)8,9-dihydroxy-4-oxo-2,3,4,5-tetrahydro-1H,10cH-3a,5,10b-triazaacephenantrylene-1-carb-oxylic acid -and a decapeptide chain linked with the N-terminus to the carboxy group of the chromophore containing also modified, non-proteinogenic amino acids. The sequence L-Ser-D-Ser-L-Hse-Gly-D-threo-OHAsp-Hse-Hse-Hse-D-N5OH-N5-R-Hbu-Om-L-Hse was determined for Az 87-1, while Az 87-11 contains a C-terminal L-Hse-lactone instead. Iron is chelated by the catecholic group of the chromophore, the β-hydroxy aspartic acid, and the hydroxamate function formed by N5-hydroxyornithine and R-β-hydroxybutyric acid.

Dicyano-bis(pyridin-2,6-dicarbothioato)-ferrat (II)/ferrat (III), ein weiteres eisenhaltiges Redoxsystem aus der Kulturlösung eines Pseudomonas-Stammes [1] / Dicyano-bis(pyridin-2,6-dicarbothioato)-ferrate (II)/ferrate (III), a Further Fe Containing Redox System from the Culture Medium of Pseudomonas sp.

1985 ◽  
Vol 40 (3-4) ◽  
pp. 201-207 ◽  
Author(s):  
U. Hildebrand ◽  
K. Taraz ◽  
H. Budzikiewicz ◽  
H. Korth ◽  
G. Pulverer
Keyword(s):  
Pseudomonas Putida ◽  
Culture Medium ◽  
Redox System ◽  
Pseudomonas Sp ◽  
Redox Potentials ◽  
Bacterial Strains ◽  
Normal Potential

From the culture medium of Pseudomonas sp. a further Fe containing complex, viz. dicyano- bis(pyridin-2,6-dicarbothioato)-ferrate (III) (2) has been isolated which participates in a ferrate (II)/ferrate (III) redox system (normal potential of-0.013 V) in the range of the redox potentials of cytochromes. Pyridine-2,6-di(monothiocarboxylic acid) which originally has been considered to be characteristic for Pseudomonas putida has been found recently as a metabolite of other bacterial strains (two of which have been characterized in this paper) as well.

Competitiveness in root colonization by Pseudomonas putida requires the rpoS gene

2001 ◽  
Vol 47 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Charles D Miller ◽  
Young-Cheol Kim ◽  
Anne J Anderson
Keyword(s):  
Pseudomonas Putida ◽  
Culture Medium ◽  
Wild Type Strain ◽  
Root Colonization ◽  
Plant Root ◽  
Wild Type ◽  
Rpos Gene ◽  
Activated Oxygen ◽  
Increased Sensitivity ◽  
Dose Dependent

The rpoS gene in Pseudomonas putida was essential for plant root colonization under competitive conditions from other microbes. The RpoS- mutant survived less well than the wild-type strain in culture medium, and unlike the wild-type, failed to colonize the roots in a peat matrix containing an established diverse microflora. The RpoS-deficient P. putida isolate was generated by insertion of a glucuronidase-npt cassette into the rpoS gene. The RpoS- mutant had dose-dependent increased sensitivity to oxidative stress and produced Mn-superoxide dismutase activity earlier than the parent. While extracts from wild-type P. putida stationary-phase cells contained three isozymes of catalase (CatA, CatB, and CatC), the σ38-deficient P. putida lacked CatB. These results are consistent with previous findings that CatB is induced in stationary-phase.Key words: catalase, starvation, activated oxygen species.

Facile and efficient synthesis of a new class of bis(3′-indolyl)pyridine derivatives via one-pot multicomponent reactions

2008 ◽  
Vol 49 (11) ◽  
pp. 1777-1781 ◽  
Author(s):  
Song-Lei Zhu ◽  
Shun-Jun Ji ◽  
Xiao-Ming Su ◽  
Chang Sun ◽  
Yu Liu
Keyword(s):  
Multicomponent Reactions ◽  
Pyridine Derivatives ◽  
Efficient Synthesis ◽  
One Pot ◽  
New Class
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