Relationship between blood group and gastric carcinoma in Erbil city: A case-control study

Background and objective: Gastric carcinoma can be caused by the interaction between environmental factors and genetic variations. The relationship between ABO blood groups and carcinogenesis or progression of human tumors has been reported by many investigations. This study aimed to understand the correlation between ABO blood groups and the risk of developing gastric carcinoma. Methods: This case-control study included the ABO blood group and rhesus system of 92 patients diagnosed with gastric carcinoma at Erbil city from 2017 to 2019. Informed consent was obtained from all patients. As a control, the blood group from 260 healthy blood donors was collected from Erbil blood bank. Results: Of 92 patients, 58.7% were males, and 41.3% were females. The mean age was 62 (28 - 97) years. Regarding the type of gastric carcinoma, 58.7% were intestinal, and 41.3% were diffuse type. Blood group and rhesus system of patients and control were compared. Blood group O was 47.8% in cases versus 40.8% in control and 42.6% in all participants, followed by blood group A (31.5% of gastric carcinoma patients and 26.5% of control with a total of 27.8% of all participants). Regarding the Rhesus system, 92.4% of cases were Rh+, and 7.6% were Rh- compared with 92.9% Rh+and 7.1% Rh- in control. None of them was statistically significant. Conclusion: There was no statistically significant association between blood groups and gastric carcinoma, although blood group O was more common, followed by A. Keywords: Gastric carcinoma; ABO blood group; Erbil.

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Association between ABO and Rh Blood Groups and Risk of Preeclampsia: A Case-Control Study from Iran

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2017.002 ◽

2017 ◽

Vol 5 (2) ◽

pp. 173-176

Author(s):

Firoozeh Aghasadeghi ◽

Mostafa Saadat

Keyword(s):

Blood Group ◽

Case Control Study ◽

Neonatal Morbidity ◽

Case Control ◽

Blood Groups ◽

Iranian Population ◽

Control Group ◽

Abo Blood Groups ◽

Control Study ◽

Risk Of Preeclampsia

AIM: Preeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality. There is a genetic component in the development of PE with estimated heritability around 0.47. Several studies have investigated the association between maternal ABO blood groups (OMIM: 110300) and risk of PE, with contradictory results have emerged. Considering that there is no study in this filed from Iranian population, the present case-control study was carried out at Shiraz (south-west Iran).MATERIAL AND METHODS: In this study 331 women; 121 pregnant with PE and 210 normotensive pregnant women were included. Using blood group O (for ABO blood groups) or Rh+ (for Rh blood groups) as a reference, odds ratios (ORs) and its 95% confidence intervals (95% CI) of PE risk were estimated from logistic regression analysis.RESULTS: Although the A (OR = 0.67, 95% CI = 0.39-1.17, P = 0.165), B (OR = 0.86, 95% CI = 0.48-1.53, P = 0.615) and AB (OR = 1.14, 95% CI = 0.37-3.45, P = 0.812) phenotypes showed lower risks compared with the O blood group, statistical analysis indicated that there was no significant association between ABO phenotypes and risk of PE. The frequency of Rh- phenotype was higher among PE patients compared with the control group. However, the association was not significant (OR = 1.79, 95% CI = 0.69-4.65, P = 0.229). Adjusted ORs for age of participants and parity did not change the above-mentioned associations.CONCLUSION: Our present findings indicate that there is no association between ABO and Rh blood groups and risk of PE in Iranian population.

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Relationship between Blood Groups (ABO) and Varicose Veins of the Lower Limbs. A Case-Control Study

Phlebology The Journal of Venous Disease ◽

10.1177/026835558900400107 ◽

1989 ◽

Vol 4 (1) ◽

pp. 37-40 ◽

Cited By ~ 10

Author(s):

André Cornu-Thenard ◽

William Dab ◽

Isabelle de Vicenzi ◽

Jean Valty

Keyword(s):

Venous Thrombosis ◽

Case Control Study ◽

Varicose Veins ◽

Vascular Diseases ◽

Case Control ◽

Blood Groups ◽

Lower Limbs ◽

Abo Blood Groups ◽

Group A ◽

Control Study

Numerous studies have already shown the existence of a relationship between blood groups of the ABO system and certain vascular diseases: group A and atheromatous disease1,4,5,7,9,12; group A and deep venous thrombosis of the lower limbs6,11,13. However, no study has reported an association between varicose veins and the ABO blood groups. The aim of this study was to investigate the possible existence of such an association.

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Association of chronic viral hepatitis with ABO blood groups and rhesus (Rh) factor

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20181265 ◽

2018 ◽

Vol 6 (4) ◽

pp. 1114 ◽

Cited By ~ 1

Author(s):

Hassan Abdullah Shakeel ◽

Hamza Maqsood ◽

Basit Ali ◽

Ali Raza Khan

Keyword(s):

Viral Hepatitis ◽

Blood Donors ◽

Case Control Study ◽

Case Control ◽

Chronic Viral Hepatitis ◽

Blood Groups ◽

Abo Blood Groups ◽

Significant Difference ◽

Group A ◽

Control Study

Background: Chronic viral hepatitis includes hepatitis B and hepatitis C and is responsible for causing the deaths of millions of people all across the world each year. Although there are small studies in literature about association between ABO blood groups and chronic viral hepatitis, only few studies found relation between them. The objective of this case control study is to establish a relation between the host factors and these viral infections.Methods: This is a case control study on patients diagnosed with CVHB and CVHC. The study was conducted on 508 patients reported to Nishtar Hospital, Multan and Sheikh Zayd Hospital, Rahim Yar Khan, Pakistan.709 healthy blood donors were selected as a control group from Nishtar Hospital blood bank during December 2016 and December 2017.The results were subjected to SPSS v.20 for analysis using the chi square test. The patients and blood donors were also asked about certain demographic factors like age, sex and blood transfusions.Results: Among CVHB patients,173(100%), the distribution of blood groups was following: Group A, 38 (21.96%), B, 57 (32.94%), AB, 11 (6.35%), O, 67 (38.72%). 158 (91.32%) were Rh positive and 15 (8.67%) Rh negative. In CVHC patients, 335 (100%), the distribution was following: Group A, 69 (20.59%), B, 123 (36.71%), AB, 24 (7.16%), O, 119 (35.52%). 303 (90.44%) were Rh positive while 32 (9.55%) were Rh negative. In healthy blood donors, 167 (23.55%) were group A, 225 (31.73%) group B, 41(5.78%) group AB, 276 (38.92%) group O.632 (89.13%) were Rh positive and 77 (10.86%) Rh negative.Conclusions: There was no significant difference between blood groups(p>0.5) and Rh(p>0.5) with chronic viral hepatitis. However, it was also observed that the infections of HCV increase among (26-45) years old patients while the HBV infections increase with progression of age. Association of chronic viral hepatitis infection with blood group types needs more studies to get more knowledge about this aspect.

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Susceptibility to the novel coronavirus disease (COVID-19) is associated with ABO and Rh blood groups: a case-control study from Afghanistan

Egyptian Journal of Medical Human Genetics ◽

10.1186/s43042-020-00124-x ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Khyber Saify ◽

Mohammad Sarwar Alborz ◽

Mostafa Saadat

Keyword(s):

Blood Group ◽

Case Control Study ◽

Statistical Significance ◽

Case Control ◽

Blood Groups ◽

Control Group ◽

North East ◽

Group A ◽

Novel Coronavirus ◽

Control Study

Abstract Background There are preliminary studies about the association between COVID-19 and ABO phenotypes and the results are controversial. There are only two studies which investigated the association of Rh blood groups in addition to ABO with COVID-19; however, in the statistical analysis ABO and Rh blood groups have been considered separately. Therefore, the present case-control study was performed to determine the association of COVID-19 with ABO blood groups considering the Rh blood groups simultaneously. The study was conducted in Kunduz COVID-19 treatment specific center, Spin-Zar Hospital (Kunduz Province, North East Afghanistan). A total of 301 confirmed COVID-19 cases and 1039 healthy blood donors as control group were included in the study. Results The Rh− phenotype strongly increased the risk of COVID-19 (OR = 2.97, 95% CI 1.86–3.89, P < 0.001). Although blood group A increased the risk of developing COVID-19, the association did not reach statistical significance. In analysis of the combination phenotypes, the A− blood group remarkably increased the risk of COVID-19 (OR = 7.24, 95% CI 3.62–14.4, P < 0.001). Multivariate analysis revealed that the interaction of Rh and ABO is significant (P < 0.013). Conclusion These findings indicate that susceptibility to COVID-19 is strongly associated with A− blood group.

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Is There a Relation between ABO Blood Groups and Clinical Outcome in Patients with Pemphigoid? A Case-Control Study

Dermatology Research and Practice ◽

10.1155/2016/3916750 ◽

2016 ◽

Vol 2016 ◽

pp. 1-5 ◽

Cited By ~ 2

Author(s):

Sedigheh Bakhtiari ◽

Parviz Toosi ◽

Somayyeh Azimi ◽

Nafiseh Esmaili ◽

Ali Montazami ◽

...

Keyword(s):

Blood Group ◽

Case Control Study ◽

Case Control ◽

Blood Groups ◽

Control Group ◽

Abo Blood Groups ◽

Chi Square ◽

Chi Square Test ◽

Group B ◽

Control Study

Background.Relationship between blood groups and dermatologic diseases remains controversial and was not yet fully elucidated nor explained clearly. The aim of this study was to examine if any relation exists between different types of pemphigoid diseases and ABO blood group.Methods.In this case-control study, 159 pemphigoid patients and 152 healthy matched-controls were evaluated. All blood group (including Rh status) data for the study was obtained from the hospital medical records. Statistical comparisons were completed with chi-square test and logistic regression.Results.Blood group “O” was found in 32.9% of patients and 38.2% of control group. Blood group “A” was found among 30.8% of patients and 34.2% of control group, while group “B” was reported in 27.4% of cases and 21.1% of controls and “AB” was identified among 8.9% of patients and 6.6% of control group. 84.9% of patients were Rh positive, while in the control group 86.2% of patients were Rh positive. No significant differences were found regarding ABO blood groups (P=0.46) or Rh (P=0.76) between pemphigoid patients and control group. Also, older females had the higher risk of developing bullous pemphigoid.Conclusion.We found no relationship between ABO blood groups and pemphigoid disease.

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