Transcatheter Aortic Valve Implantation in High-risk Patients with Severe Aortic Stenosis

2012 ◽  
Vol 8 (2) ◽  
pp. 115
Author(s):  
Patricia Fonseca ◽  
Raphael Rosenhek ◽  
Vinayak Bapat ◽  
Markus Lins ◽  
◽  
...  

Aortic stenosis (AS) has become an increasingly prevalent condition in ageing Western populations. Symptomatic AS is associated with significant morbidity, high hospitalisation rates and reduction in quality of life and life-expectancy. A large number of patients with severe AS are not currently receiving proper treatment, with subsequent increased mortality. While surgical aortic valve replacement continues to be an effective treatment for these patients, transcatheter aortic valve implantation is a new alternative for those at high risk from surgery. Overall, valve replacement and implantation procedures have a significant impact on prognosis and quality of life in AS patients. Referring a patient to a centre that has a multidisciplinary heart team will ensure that all treatment options are fully explored and the best clinical outcomes are reached.

2018 ◽  
Vol 9 (1) ◽  
pp. 84-89
Author(s):  
Alexey V. Sizov ◽  
Alexey S. Sergeev ◽  
Evgeny A. Shloydo ◽  
Valentin K. Suchov ◽  
Victoria V. Zvereva

Aortic stenosis is the most common disease from the group of acquired heart diseases. The frequency and degree of damage of the aortic valve increases with age. The prevalence of this disease increases due to the general extension in life expectancy of the population. Aortic valve stenosis caused by calcification is the pathology with progressive course characterized by a poor prognosis at the stage of expanded symptoms. Five-year survival of patients with developed clinical picture of aortic stenosis without surgery, according to some estimates, is reduced to 15%, which is the worst figure, even in comparison with most potentially incurable cancer. In the treatment of aortic stenosis aortic valve replacement is the “gold standard” and gives positive results in all age groups of patients. Only one third of patients are sent for aortic valve replacement owing to high risk caused by the age, severity of the defect, reduced contractility of the left ventricle, pulmonary hypertension and other comorbidities. Aortic valve replacement in patients of the older age groups with concomitant diseases is associated with high level of hospital mortality. One of the attempts to reduce the frequency of complications and mortality in this group of patients is the implementation of a less traumatic surgery – transcatheter aortic valve implantation. At present our clinic has successfully performed more than 70 operations of transcatheter aortic valve implantation. Transcatheter aortic valve implantation is a good alternative to standard aortic valve replacement in patients with high risk of open-heart surgery.


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