scholarly journals “Heart full of thrombi”. Post COVID-19 multisite thrombosis assessed by echocardiography and pulmonary CT

Imaging ◽  
2021 ◽  
Author(s):  
I. Mitevska ◽  
E Grueva Nastevska ◽  
E. Kandic ◽  
O. Busljetik

AbstractThrombosis in general, and especially venous thromboembolism (VTE) is one of the most common complications associated with COVID-19 infection. We present a 48 years old male patient with dyspnea and severe multisite post Covid-19 disease thrombotic complications, with pattern never seen before, that includes both ventricles, pulmonary arteries and peripheral vein involvement, assessed by echocardiography, vascular ultrasound and pulmonary CT angiography.

2008 ◽  
Vol 191 (3) ◽  
pp. 885-889 ◽  
Author(s):  
Guillaume Bierry ◽  
Nathalie Holl ◽  
Frauke Kellner ◽  
Sophie Riehm ◽  
Marie-Noelle Roedlich ◽  
...  

2021 ◽  
Vol 27 ◽  
pp. 107602962110131
Author(s):  
Bela Woller ◽  
Austin Daw ◽  
Valerie Aston ◽  
Jim Lloyd ◽  
Greg Snow ◽  
...  

Real-time identification of venous thromboembolism (VTE), defined as deep vein thrombosis (DVT) and pulmonary embolism (PE), can inform a healthcare organization’s understanding of these events and be used to improve care. In a former publication, we reported the performance of an electronic medical record (EMR) interrogation tool that employs natural language processing (NLP) of imaging studies for the diagnosis of venous thromboembolism. Because we transitioned from the legacy electronic medical record to the Cerner product, iCentra, we now report the operating characteristics of the NLP EMR interrogation tool in the new EMR environment. Two hundred randomly selected patient encounters for which the imaging report assessed by NLP that revealed VTE was present were reviewed. These included one hundred imaging studies for which PE was identified. These included computed tomography pulmonary angiography—CTPA, ventilation perfusion—V/Q scan, and CT angiography of the chest/ abdomen/pelvis. One hundred randomly selected comprehensive ultrasound (CUS) that identified DVT were also obtained. For comparison, one hundred patient encounters in which PE was suspected and imaging was negative for PE (CTPA or V/Q) and 100 cases of suspected DVT with negative CUS as reported by NLP were also selected. Manual chart review of the 400 charts was performed and we report the sensitivity, specificity, positive and negative predictive values of NLP compared with manual chart review. NLP and manual review agreed on the presence of PE in 99 of 100 cases, the presence of DVT in 96 of 100 cases, the absence of PE in 99 of 100 cases and the absence of DVT in all 100 cases. When compared with manual chart review, NLP interrogation of CUS, CTPA, CT angiography of the chest, and V/Q scan yielded a sensitivity = 93.3%, specificity = 99.6%, positive predictive value = 97.1%, and negative predictive value = 99%.


2017 ◽  
Vol 208 (3) ◽  
pp. 632-636 ◽  
Author(s):  
Matthew A. Zapala ◽  
David Zurakowski ◽  
Edward Y. Lee

2015 ◽  
Vol 205 (2) ◽  
pp. 271-277 ◽  
Author(s):  
Barry Donald Hutchinson ◽  
Patrick Navin ◽  
Edith M. Marom ◽  
Mylene T. Truong ◽  
John F. Bruzzi

2017 ◽  
Vol 11 (6) ◽  
pp. 455-461 ◽  
Author(s):  
Daniel R. Obaid ◽  
Patrick A. Calvert ◽  
Adam Brown ◽  
Deepa Gopalan ◽  
Nick E.J. West ◽  
...  

2015 ◽  
Vol 113 (01) ◽  
pp. 201-208 ◽  
Author(s):  
Ji-hyun Kwon ◽  
Sung Yoon ◽  
Leo Song ◽  
Jae-Ho Yoon ◽  
Seung-Hwan Shin ◽  
...  

SummaryDue to the high risk of thrombocytopenia and haemorrhage, thrombotic complications have received little attention in patients with acute myeloid leukemia (AML). Furthermore, the predictive role of cytogenetics on venous thromboembolism (VTE) has largely been ignored. This study aimed to evaluate the incidence, risk factors, and prognostic aspects of VTE in AML. A total of 811 consecutive patients with AML were enrolled and analysed retrospectively. Cox time-dependent covariate regression analysis was used to identify the significant predictors of VTE development. To minimise potential confounding factors, we used propensity-score matching to compare overall survival between patients with and without VTE. The six-month and one-year cumulative incidences of VTE were 3.1 % (95 % confidence interval [CI], 2.0–4.7) and 3.9 % (95 % CI, 2.6–5.7), respectively. Of the 26 cases of VTE, 22 (85 %) developed within 6 months of leukemia diagnosis and 13 (50 %) were catheter-related. In multivariate analysis, advanced age (≥ 65 years) (hazard ratio [HR], 2.70; p = 0.03) and increasing cytogenetic risk (common HR, 1.84; p = 0.05) were independent predictors of VTE. There was no significant association between VTE development and decreased survival (p = 0.32 for matched analysis). Advanced age and increasing cytogenetic risk, well-known predictors for clinical outcome in AML, were also independent risk factors of VTE development. Our results suggest that VTE does not hold prognostic implications for AML.


Author(s):  
Gary Mikhjian ◽  
Ahmad Elghoroury ◽  
Keith Cronovich ◽  
Kevin Brody ◽  
Robert Jarski
Keyword(s):  
D Dimer ◽  

2021 ◽  
Author(s):  
Monika Zdanyte ◽  
Dominik Rath ◽  
Meinrad Gawaz ◽  
Tobias Geisler

AbstractSARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection is associated with high risk of venous and arterial thrombosis. Thrombotic complications, especially pulmonary embolism, lead to increased all-cause mortality in both intensive care unit and noncritically ill patients. Damage and activation of vascular endothelium, platelet activation, followed by thrombotic and fibrinolytic imbalance as well as hypercoagulability are the key pathomechanisms in immunothrombosis leading to a significant increase in thromboembolism in coronavirus disease 2019 (COVID-19) compared with other acute illnesses. In this review article, we discuss the incidence and prognosis, diagnosis, prevention, and treatment of venous thromboembolism in patients with COVID-19 disease, based on clinical experience and research available to date.


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