scholarly journals MOLECULAR HYDROGEN GENERATOR GVCH LIFE

2021 ◽  
pp. 65-68
Author(s):  
Volodymyr Moseichuk ◽  
Vladyslav Moseichuk ◽  
Vasyl Makolinets
Keyword(s):  
Musculoskeletal System ◽  
Molecular Hydrogen ◽  
Water Concentration ◽  
Hydrogen Gas ◽  
The Body ◽  
Water Volume ◽  
Antioxidant Systems ◽  
Pure Hydrogen ◽  
Hydrogen Generator ◽  
Hydrogen Water

Molecular hydrogen is one of the effective antioxidants, which not only does not disrupt normal metabolism in the body, but also activates its antioxidant systems. Hydrogen-saturated water has  antioxidant, anti-inflammatory, anti-allergic, anti-apoptotic properties, stimulates energy metabolism and contributes to the systemic recovery of the body. It is used as a therapeutic factor for the treatment of patients with various pathologies: arterial hypertension, coronary heart disease, diabetes, obesity, metabolic disorders, disorders of the musculoskeletal system. The article discusses the various methods of obtaining molecular hydrogen and hydrogen water (direct and indirect saturation). Technical characteristics are described and features of the hydrogen generator GVCh Life (manufacturer LTD «Chemtest Ukraine+», Kharkiv, Ukraine), which produces molecular hydrogen (purity of which is 99.99 %, productivity — 100 ml/min) and saturates water with it (https://chemtest.com.ua/generator_vodorodnoy_vodi_i_dihanie_gvch_life). In contrast to the problems of most known generators in the device GVChLife is completely no contact of the electrodes with water, so it is not subject to electrolysis and is not saturated with metal ions. Water saturated in this way has the following characteristics: redox potential 560 mV, hydrogen concentration 1.0–1.15 ppm(water volume 1 l, saturation duration 10 min). The generator can be used for both hydrogen saturation and hydrogen inhalation. In the case of therapeutic use of hydrogen water to obtain it, you can use any drinking water (spring, prepared or non-carbonated bottled), hydrogen inhalation using nasal cannulas. Inhalation of pure hydrogen gas (99.99 %) for 30 minutes is equal to the use of 15 liters of hydrogen water (concentration 1.1–1.2 ppm). Conclusions. The developed MoHC Life molecular hydrogen generator is safe to use, without special requirements during operation. It can be successfully used in the complex therapy of patients with various diseases, including musculoskeletal system.

scholarly journals Observations on the theory of respiration

1837 ◽  
Vol 3 ◽  
pp. 334-335
Keyword(s):  
Carbonic Acid ◽  
Venous Blood ◽  
Hydrogen Gas ◽  
The Body ◽  
Pure Hydrogen ◽  
Atmospheric Air ◽  
Acid Gas ◽  
Arterial Blood ◽  
Dark Colour ◽  
Oxygen Gas

From the fact that no carbonic acid gas is given out by venous blood when that fluid is subjected to the action of the air-pump, former experimentalists had inferred that this blood contains no carbonic acid. The author of the present paper contends that this is an erroneous inference; first, by showing that serum, which had been made to absorb a considerable quantity of this gas, does not yield it upon the removal of the atmospheric pressure; and next, by adducing several experiments in proof of the strong attraction exerted on carbonic acid both by hydrogen and by oxygen gases, which were found to absorb it readily through the medium of moistened membrane. By means of a peculiar apparatus, consisting of a double-necked bottle, to which a set of bent tubes were adapted, he ascertained that venous blood, agitated with pure hydrogen gas, and allowed to remain for an hour in contact with it, imparts to that gas a considerable quantity of carbonic acid. The same result had, indeed, been obtained, in a former experiment, by the simple application of heat to venous blood confined under hydrogen gas; but on account of the possible chemical agency of heat, the inference drawn from that experiment is less conclusive than from experiments in which the air-pump alone is employed. The author found that, in like manner, atmospheric air, by remaining, for a sufficient time, in contact with venous blood, on the application of the air-pump, acquires carbonic acid. The hypothesis that the carbon of the blood attracts the oxygen of the air into the fluid, and there combines with it, and that the carbonic acid thus formed is afterwards exhaled, appears to be inconsistent with the fact that all acids, and carbonic acid more especially, impart to the blood a black colour; whereas the immediate effect of exposing venous blood to atmospheric air, or to oxygen gas, is a change of colour from a dark to a bright scarlet, implying its conversion from the venous to the arterial character: hence the author infers that the acid is not formed during the experiment in question, but already exists in the venous blood, and is extracted from it by the atmospheric air. Similar experiments made with oxygen gas, in place of atmospheric air, were attended with the like results, but in a more striking degree and tend therefore to corroborate the views entertained by the author of the theory of respiration. According to these views, it is neither in the lungs, nor generally in the course of the circulation, but only during its passage through the capillary system of vessels, that the blood undergoes the change from arterial to venous; a change consisting in the formation of carbonic acid, by the addition of particles of carbon derived from the solid textures of the body, and which had combined with the oxygen supplied by the arterial blood: and it is by this combination that heat is evolved, as well as a dark colour imparted to the blood. The author ascribes, however, the bright red colour of arterial blood, not to the action of oxygen, which is of itself completely inert as a colouring agent, but to that of the saline ingredients naturally contained in healthy blood. On arriving at the lungs, the first change induced on the blood is effected by the oxygen of the atmospheric air, and consists in the removal of the carbonic acid, which had been the source of the dark colour of the venous blood; and the second consists in the attraction by the blood of a portion of oxygen, which it absorbs from the air, and which takes the place of the carbonic acid. The peculiar texture of the lungs, and the elevation of temperature in warm-blooded animals, concur in promoting the rapid production of these changes.

Impacts of H2 Blending on Capacity and Efficiency on a Gas Transport Network

2019 ◽  
Author(s):  
Francis Bainier ◽  
Rainer Kurz
Keyword(s):  
Natural Gas ◽  
Molecular Hydrogen ◽  
Gas Transport ◽  
Energy Requirement ◽  
Calorific Value ◽  
Hydrogen Gas ◽  
Transport Network ◽  
Pure Hydrogen ◽  
Pipeline Network ◽  
Methane Gas

Abstract Gas Transport System Operators (TSO1) are considering injecting hydrogen gas in their networks. Blending hydrogen into the existing natural gas pipeline network appears to be a strategy for storing and delivering renewable energy to markets [1], [2],[3]. In comparison to methane, hydrogen gas (dihydrogen or molecular hydrogen) has a higher mass calorific value than methane gas. Because of this property, molecular hydrogen is appreciated for space shuttle engines. A second property is that hydrogen gas has a lower mass density than methane gas. The result of the second property is that the volume calorific value is in favor of methane gas. The list of differences between methane and hydrogen is long. In the relevant range of pressures and temperatures, the Joule-Thomson coefficient has a different sign for hydrogen and methane, and the compressibility factor has the opposite trend when the gas is compressed. The dynamic viscosity is also significantly different, and finally, heat capacity, isentropic exponent, and the thermal conductivity are also different. What are the impacts of these hydrogen characteristics on the transport capacity and its efficiency in the case of blending in a gas transport network? The first part of the paper is a review of the differences in characteristics between Hydrogen Gas and a Typical Natural Gas in Europe and their impact on the gas flow performance in a pipeline network equipped with compressors. The second part of the paper is dedicated to pipe segments. And in the third part, compressor stations are introduced between each pipe segment. At each step, an analysis of a mixed gas from one hundred per cent pure natural gas to one hundred per cent pure hydrogen is done. The paper provides some results for 10 %, 40 %, and 100 % of hydrogen blending in an international pipeline. The study shows that the energy quantity transported at the same pressure ratio is reduced respectively by 4 %, 14 %, and 15 to 20 %, and energy requirement for compression increases respectively by 7 %, 30 %, and 210 % (i.e. it more than triples). To transport the same quantity of energy in a network, assuming the resizing to the same level of optimizations, the energy requirement increases by 11 %, 52 %, and 280 %. In other words, it takes 4 times the energy to transport a given amount of energy if the gas is pure hydrogen than it takes if the gas is pure natural gas. The paper does not address the issue of equipment or material, it only compares the influence of hydrogen gas on the network capacity and the transport efficiency. This paper doesn’t take into account the limits of the equipment. All equipment is considered as compatible with any load of hydrogen blending.

scholarly journals On the Star Formation in Early Stage of Galactic Evolution

1981 ◽  
Vol 93 ◽  
pp. 68-69
Author(s):  
Y. Yoshii ◽  
Y. Sabano
Keyword(s):  
Molecular Hydrogen ◽  
Thermal Instability ◽  
Heavy Element ◽  
Hydrogen Gas ◽  
Initial Mass Function ◽  
Element Abundance ◽  
Subsequent Stage ◽  
Pure Hydrogen ◽  
Wide Range ◽  
Gas Cloud

Evolution and fragmentation of a gas cloud are investigated for the primordial chemical composition which is the same as the products of the Big Bang. A pure-hydrogen gas cloud collapses isothermally at 500–1000 K when a low fraction of molecular hydrogen works as a coolant, and breaks into small subcondensations with mass less than 10 M⊙ due to thermal instability associated with molecular dissociation. On the other hand a pure-hydrogen gas cloud which contains no molecular hydrogen collapses isothermally at 6000–8000 K in a thermally stable condition, and enters the region where thermal energy exceeds radiation energy when thermal equilibrium between matter and radiation is achieved in the cloud. Consideration of energetics in the subsequent stage of the cloud evolution leads to the mass range of 0.1–20 M⊙ for the stable nuclear-burning protostars of the first generation. The thermal behavior of a gas cloud in the regime of z (the ratio of heavy element abundance to solar one) less than 10−4 is essentially similar to that in the case of no heavy element, and the heavy element cooling brings about thermal instability in a wide range of parameters in the regime of z greater than 10−3. Linear perturbation analysis gives growth time of the instability much shorter than the free-fall time, and suggests the efficient excitation of density fluctuation driven by thermal instability. Thus the possibility of the initial mass function relatively enhanced in massive star at early times is denied, and the slow rate of metal enrichment in the interstellar medium is suggested.

scholarly journals STATE AND PROSPECTS USING MOLECULAR HYDROGEN FOR ATHLETES

2020 ◽  
Vol 1 ◽  
pp. 443-450
Author(s):  
Oleg Pokotylo ◽  
◽  
Ivan Zakharchuk ◽  
Borys Vykhovanets ◽  
◽  
...  
Keyword(s):  
Sports Medicine ◽  
Molecular Hydrogen ◽  
The Body ◽  
Alternative Mechanism ◽  
Physically Active ◽  
Hydrogen Water ◽  
Positive Effects ◽  
Advantages And Disadvantages ◽  
The Individual ◽  
Effective Use

Introduction. The study of molecular hydrogen as the latest therapeutic and prophylactic corrector of metabolism has been successfully tested on more than 170 models of pathological conditions. Its effective antioxidant, cytoprotective, anti-inflammatory effect on the body has been proven. Separate studies of the effects of molecular hydrogen have been conducted on athletes. The aim of the study - to investigate the level of research and efficiency of using molecular hydrogen in sports medicine and to predict the algorithm of its further research and practical use. Research Methods: Analysis, generalization of data of professional scientific literature for researching the effect of molecular hydrogen in physical culture and sports and identify opportunities and criteria for its use for athletes and physically active people Results. An analytical study based on the results of professional publications about the effective use of molecular hydrogen for athletes in the world was conducted. The advantages and disadvantages of using molecular hydrogen for the organism are reasoned. Ways and methods of entry of molecular hydrogen into the body are described. Inventions of molecular hydrogen generators of Ukrainian scientists, their advantages over foreign analogues and possibilities of their application in sports are shown. Conclusions. Today in view of the analysis of the situation with the use of molecular hydrogen for therapeutic and prophylactic purposes in medicine and sports medicine in particular, the algorithm of prospects for its further research and practical application follows. Firstly, to study the optimal protocol for the intake of molecular hydrogen, depending on the intensity of physical activity, body weight, age, sex, comorbidities, etc.; secondly, to develop personalized antioxidant strategies for the using molecular hydrogen, taking into account the individual redox characteristics of individuals; thirdly, to investigate the consequences of long-term intake of H2 during exercise; fourthly, to reveal the alternative mechanism underlying the antioxidant action and other positive effects of molecular hydrogen. Key words: sports medicine, hydrogen water, «TIG «Liwing Water»», redox potential, oxidative stress.

scholarly journals Molecular hydrogen as a possible therapeutic factor in complex rehabilitation therapy in patients with muscular skeletal disorders (literature review)

2021 ◽  
pp. 92-97
Author(s):  
Vasyl Makolinets ◽  
Tamara Grashenkova ◽  
Volodymyr Moseichuk ◽  
Kyrylo Makolinets ◽  
Vladyslav Moseichuk
Keyword(s):  
Free Radicals ◽  
Molecular Hydrogen ◽  
The Body ◽  
Matrix Proteins ◽  
Cartilage Tissue ◽  
Joint Diseases ◽  
Chain Reactions ◽  
Hydrogen Water ◽  
Normal Metabolism ◽  
The Brain

The paper presents an analysis of foreign scientific and medical data on the therapeutic factor — molecular hydrogen. The effectiveness of its application in the complex therapy of many diseases is revealed. The effect is achieved due to the small size of the mo­lecule, which passes through biological membranes and inhibits dangerous free radicals in the mitochondria, as well as in the nuc­leus, which reduces the possibility of DNA damaging. Molecular hydrogen neutralizes oxidants in the brain due to its ability to cross the blood-brain barrier. It normalizes the functions and metabolic processes in the body and, as an antioxidant, is selective: it does not affect the useful free radicals involved in important metabo­lic processes and selectively eliminates only the most dangerous oxidants — hydroxyl radicals. Interacting with them, hydrogen converts them into water molecules without the formation of by-products and chain reactions. Unlike other known antioxidants, molecular hydrogen does not disrupt normal metabolism, does not cause negative changes in cells, activates the body’s own anti­oxidant systems. The possibility and expediency of the use of molecular hydrogen in the case of pathology of the musculoskeletal system has been confirmed. The peculiarities of its effect on bone and cartilage tissue in the experiment are shown. It has been determined that the use of molecular hydrogen is a new pharmacological strategy aimed at the selective removal of ONOO—, and can be an effective method in the treatment of joint diseases. Because cartilage receives nutrients through a diffusion-loading mechanism, and molecular hydrogen penetrates rapidly into tissues, it can be useful for the prevention of diseases of joints of degenerative origin. It reduces oxidative stress and slows down the reduction of matrix proteins and inhibition of proteinase degradation. Its effectiveness has been proven after injuries to the spinal cord, muscles and tendons, comorbid diseases such as hypertension, coronary heart disease, diabetes and metabolic syndrome. Key words. Molecular hydrogen, hydrogen water, hydrogen inhalations, joint diseases, consequences of musculoskeletal injuries, comorbid pathology.

scholarly journals Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression, evoking oxidative stress, and activating inflammation and apoptosis

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Shuang Li ◽  
Wenjuan Sun ◽  
Kai Zhang ◽  
Jiawei Zhu ◽  
Xueting Jia ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Inflammatory Cytokines ◽  
The Body ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Antioxidant Systems ◽  
Tunel Staining ◽  
White Pulp ◽  
Sibling Pairs ◽  
Se Deficiency ◽  
Spleen Index

Abstract Background The immune system is one aspect of health that is affected by dietary selenium (Se) levels and selenoprotein expression. Spleen is an important immune organ of the body, which is directly involved in cellular immunity. However, there are limited reports on Se levels and spleen health. Therefore, this study established a Se-deficient pig model to investigate the mechanism of Se deficiency-induced splenic pathogenesis. Methods Twenty-four pure line castrated male Yorkshire pigs (45 days old, 12.50 ± 1.32 kg, 12 full-sibling pairs) were divided into two equal groups and fed Se-deficient diet (0.007 mg Se/kg) or Se-adequate diet (0.3 mg Se/kg) for 16 weeks. At the end of the trial, blood and spleen were collected to assay for erythroid parameters, the osmotic fragility of erythrocytes, the spleen index, histology, terminal deoxynucleotidyl transferase nick-end labeling (TUNEL) staining, Se concentrations, the selenogenome, redox status, and signaling related inflammation and apoptosis. Results Dietary Se deficiency decreased the erythroid parameters and increased the number of osmotically fragile erythrocytes (P < 0.05). The spleen index did not change, but hematoxylin and eosin and TUNEL staining indicated that the white pulp decreased, the red pulp increased, and splenocyte apoptosis occurred in the Se deficient group. Se deficiency decreased the Se concentration and selenoprotein expression in the spleen (P < 0.05), blocked the glutathione and thioredoxin antioxidant systems, and led to redox imbalance. Se deficiency activated the NF-κB and HIF-1α transcription factors, thus increasing pro-inflammatory cytokines (IL-1β, IL-6, IL-8, IL-17, and TNF-α), decreasing anti-inflammatory cytokines (IL-10, IL-13, and TGF-β) and increasing expression of the downstream genes COX-2 and iNOS (P < 0.05), which in turn induced inflammation. In addition, Se-deficiency induced apoptosis through the mitochondrial pathway, upregulated apoptotic genes (Caspase3, Caspase8, and Bak), and downregulated antiapoptotic genes (Bcl-2) (P < 0.05) at the mRNA level, thus verifying the results of TUNEL staining. Conclusions These results indicated that Se deficiency induces spleen injury through the regulation of selenoproteins, oxidative stress, inflammation and apoptosis.

scholarly journals Hyaluronan and the Fascial Frontier

2021 ◽  
Vol 22 (13) ◽  
pp. 6845
Author(s):  
Rebecca L. Pratt
Keyword(s):  
Nerve Fibers ◽  
The Body ◽  
Water Volume ◽  
Cell Behavior ◽  
Connective Tissues ◽  
Wide Range ◽  
The World ◽  
Extracellular Microenvironment ◽  
The Impact ◽  
The Relationship

The buzz about hyaluronan (HA) is real. Whether found in face cream to increase water volume loss and viscoelasticity or injected into the knee to restore the properties of synovial fluid, the impact of HA can be recognized in many disciplines from dermatology to orthopedics. HA is the most abundant polysaccharide of the extracellular matrix of connective tissues. HA can impact cell behavior in specific ways by binding cellular HA receptors, which can influence signals that facilitate cell survival, proliferation, adhesion, as well as migration. Characteristics of HA, such as its abundance in a variety of tissues and its responsiveness to chemical, mechanical and hormonal modifications, has made HA an attractive molecule for a wide range of applications. Despite being discovered over 80 years ago, its properties within the world of fascia have only recently received attention. Our fascial system penetrates and envelopes all organs, muscles, bones and nerve fibers, providing the body with a functional structure and an environment that enables all bodily systems to operate in an integrated manner. Recognized interactions between cells and their HA-rich extracellular microenvironment support the importance of studying the relationship between HA and the body’s fascial system. From fasciacytes to chronic pain, this review aims to highlight the connections between HA and fascial health.

scholarly journals Oxidative stress in ageing

2017 ◽  
Vol 5 (11) ◽  
pp. 4826 ◽  
Author(s):  
Fasna K. A. ◽  
Geetha N. ◽  
Jean Maliekkal
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Free Radicals ◽  
Free Radical ◽  
Age Groups ◽  
The Body ◽  
Antioxidant Systems ◽  
Lipid Peroxidation Product ◽  
Free Radical Theory ◽  
Radical Theory

Background: Ageing is characterized by a gradual decline in body functions and decreased ability to maintain homeostasis. The free radical theory of ageing proposed by Harman D states that ageing is a result of cumulative damage incurred by free radical reactions. Free radicals are highly reactive molecular species with unpaired electrons; generated in the body by several physiological processes. Prime target to free radical attack are the polyunsaturated fatty acids of cell membranes causing lipid peroxidation. The free radicals are neutralized by the exogenous and endogenous antioxidant systems. Oxidative stress occurs when large number of free radicals are produced or the antioxidant activity is impaired. The present study is focused to find out the role of oxidative stress in ageing.Methods: A cross sectional observational study was undertaken to assess the oxidative stress in ageing; by determining the levels of lipid peroxidation product- malondialdehyde (MDA), the antioxidants- superoxide dismutase (SOD) and ceruloplasmin in various age groups. 150 healthy subjects were selected randomly and categorised into three different age groups of 20-30 years, 40-59 years and 60-90 years; with 50 subjects in each group. Results were expressed as mean ± standard deviation.Results: a significant elevation in serum MDA level and a decline in SOD were observed in 40-59 years and 60-90 years age groups. However, an elevated ceruloplasmin level was found in the above age groups.Conclusions: Aforementioned observations are suggestive of an association between oxidative stress and the progression of ageing process.

scholarly journals Prooxidant and antioxidant activity of blood plasma and histology of internal organs of rats after intravenous administration of magnetite nanoparticles

2013 ◽  
Vol 59 (3) ◽  
pp. 330-338 ◽  
Author(s):  
I.V. Milto ◽  
T.K. Klimenteva ◽  
I.V. Suhodolo ◽  
N.A. Krivova
Keyword(s):  
Antioxidant Activity ◽  
Blood Plasma ◽  
Intravenous Administration ◽  
Magnetite Nanoparticles ◽  
The Body ◽  
Antioxidant Systems ◽  
Internal Organs ◽  
Intravenous Injections ◽  
Magnetite Particles ◽  
Dose Dependent

The effect of a single and multiple intravenous injections of a nanosized magnetite suspension on total prooxidant and antioxidant activity of blood plasma has been investigated by the method of luminol-dependent chemoluminescence. Magnetite nanoparticles possess dose-dependent prooxidant properties due to their iron atoms and at the same time their trigger compensatory activation of antioxidant systems in the rat blood plasma. After a single intravenous administration of magnetite the studied parameters of blood plasma returned to the normal level by the end of the experiment as due to removal of nanoparticles from the body. In the case of multiple administration of the magnetite suspension dose-dependent changes in the pro- and antioxidant plasma activity persist during the whole experiment. Accumulation of magnetite particles in the cells of the mononuclear phagocytic system in the rats’ liver, lungs and kidneys is associated with hemodynamic damages, local dystrophic and necrotic changes of parenchyma in these organs. After a single intravenous injection magnetite nanoparticles are identified in the rat organs for 40 days, but their number decreases by the end of the experiment.

scholarly journals Features of free oxidation in liver homogenates of rats in combined action of copper and subtoxic level of stearate potassium and sodium

2016 ◽  
Author(s):  
O. V. Lototska
Keyword(s):  
Free Radical ◽  
Liver Homogenate ◽  
Sodium Stearate ◽  
Free Radical Oxidation ◽  
The Body ◽  
Antioxidant Systems ◽  
Radical Oxidation ◽  
Combined Action ◽  
Liver Homogenates ◽  
Free Oxidation

Toxic effects of heavy metals on animals and humans is aggravating the presence of surfactants. The aim of our research was to identify the peculiarities of free radical oxidation and antioxidant protection in the use of drinking water with subtoxic doses of potassium and sodium stearates in combination with copper on the body of warmblooded animals, such as the liver of experimental rats. Analysis of indicators allows asserting that in experimental rats liver homogenate observed activation of free radical oxidation, the intensity of which depended on the concentration of stearates in water. More pronounced changes were in animals that consumed water with potassium stearate.The action of potassium stearate observed inhibition of antioxidant systems while under the influence of sodium stearate – its activation. Changes in performance were more pronounced in combination stearates with copper.

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