scholarly journals SJS/TENN: A Mnemonic for Early Clinical Diagnosis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

2021 ◽  
Vol 14 ◽  
pp. 114-115
Author(s):  
Brett Neill ◽  
Edward Seger ◽  
Jessica Ferguson ◽  
Tyler Hooton ◽  
Jace J. Rickstrew ◽  
...  
Keyword(s):  
Primary Care ◽  
Toxic Epidermal Necrolysis ◽  
Clinical Diagnosis ◽  
Clinical Characteristics ◽  
Primary Care Providers ◽  
Initial Diagnosis ◽  
Stevens Johnson Syndrome ◽  
Care Providers ◽  
Johnson Syndrome ◽  
Steven Johnson Syndrome

Steven Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are dermatologic emergencies that are more likely to be encountered by primary care providers rather than dermatologists. Thus, it is essential for all clinicians to be familiar with common signs associated with SJS/TEN, so as not to miss or delay the diagnosis. We designed the simple mnemonic “SJS/TENN” which describes the most frequently seen clinical characteristics in these conditions to aid in the initial diagnosis.

scholarly journals DRUG-INDUCED STEVENS-JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS

2016 ◽  
Vol 65 (4) ◽  
pp. 377-381
Author(s):  
Dalia Dop ◽  
◽  
Desdemona Stepan ◽  
Cristian Gheonea ◽  
Elena Carmen Niculescu ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Rare Diseases ◽  
Intravenous Immunoglobulins ◽  
Stevens Johnson Syndrome ◽  
Drug Induced ◽  
Johnson Syndrome ◽  
Medical Emergencies ◽  
Steven Johnson Syndrome ◽  
Restitutio Ad Integrum

Steven-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare diseases that appear following the administration of risk drugs. Both are severity grades of the same condition and are considered medical emergencies, because they are potentially lethal. They are characterized by mucocutaneous tenderness, erythema, necrosis and bullous detachment similar to extended burns. We report 3 cases of SJS/TEN in which the etiology was probably drug-related (Paracetamol, Atomoxetinum, Sulfamethoxazolum + trimethoprinum), with restitutio ad integrum following the administration of intravenous immunoglobulins.

scholarly journals A Case Study of Stevens–Johnson Syndrome-Toxic Epidermal Necrolysis (SJS-TEN) Overlap in Mycoplasma pneumoniae-Associated Tracheobronchitis

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Ranjit Sah ◽  
Samikshya Neupane ◽  
Shusila Khadka ◽  
Sagar Poudyal ◽  
Hem Raj Paneru ◽  
...  
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Mycoplasma Pneumoniae ◽  
Respiratory Tract Infections ◽  
Medical Emergency ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome ◽  
Steven Johnson Syndrome ◽  
Tract Infections ◽  
Simple Bedside

Stevens–Johnson syndrome is a medical emergency which is characterized by skin and mucosal reaction to the use of certain drugs. Atypical Steven–Johnson syndrome can occur due to various microorganisms and Mycoplasma pneumoniae being one of them. We present a clinical course, diagnosis, and successful management of Steven–Johnson syndrome-toxic epidermal necrolysis (SJS-TEN) overlap due to Mycoplasma pneumoniae in a 17-year-old Nepalese female. In the resource-limiting country and hospitals where serology and PCR for M. pneumoniae is not easily accessible, a simple bedside cold agglutination test can be done to increase the suspicion of infectious cause (most common M. pneumoniae ) of SJS-TEN overlap. M. pneumoniae infection should be considered in all cases of mucositis, especially in patients having preceding respiratory tract infections (tracheobronchitis).

scholarly journals Stevens-Johnson Syndrome in a Child on Phenytoin, Exacerbated with Cefixime

2019 ◽  
Vol 39 (3) ◽  
pp. 193-196 ◽  
Author(s):  
Yam Bahadur Roka ◽  
Sabrina Shrestha ◽  
Narayani Roka ◽  
Mohan Karki
Keyword(s):  
Toxic Epidermal Necrolysis ◽  
Whole Body ◽  
Stevens Johnson Syndrome ◽  
Intravenous Fluids ◽  
Oral Ulceration ◽  
Topical Antibiotics ◽  
Johnson Syndrome ◽  
Life Threatening ◽  
History Of ◽  
Steven Johnson Syndrome

Steven Johnson syndrome and toxic epidermal necrolysis are rare but potentially life threatening muco-cutaneous disorders. Their incidence ranges from 1.2 to six per million patient-years for Steven Johnson syndrome and 0.4 to 1.2 per million patient-years for toxic epidermal necrolysis. Drugs are the primary cause for these syndromes in majority cases. They might also be due to infections with Mycoplasma Pneumoniae or Herpes Simplex. The mortality ranges from five to 40% in these cases. We report a 10-year old girl who presented with history of multiple skin eruptions involving whole body and oral ulceration for five days. She was a known case of seizure disorder on phenytoin and had been prescribed Cefexime for fever. She was managed with intravenous fluids, corticosteroids, opiates, antacids and topical antibiotics. We want to highlight the possibility of Steven Johnson syndrome following the combination of these two drugs.

scholarly journals Drug induced Stevens Johnsons Syndrome : a case report

2018 ◽  
Vol 5 (1) ◽  
pp. 3465-3466
Author(s):  
Dr Gargi.H. Pathak ◽  
Dr Anuya Chauhan ◽  
Dr Dhriti Shukla
Keyword(s):  
Health Care Providers ◽  
Stevens Johnson Syndrome ◽  
Care Providers ◽  
Drug Induced ◽  
Antimicrobial Drugs ◽  
Topical Anesthetic ◽  
Anesthetic Agents ◽  
Johnson Syndrome ◽  
Chief Complaints ◽  
Steven Johnson Syndrome

Stevens Johnson syndrome is an acute self limited disease presenting with  severe mucosal erosions with widespread erythematous, cutaneous macules or atypical targets .The  majority of cases are drug induced affecting oral and perioral region. A 3 year old male child presented with chief complaints of fever, cough, cold , breathlessness and extensive rashes on the skin of face , oral mucosa, neck, abdomen, erythema of conjunctiva , ulceration of eyelid and oral cavity. The reaction was evoked after consumption of tab oxcarbamezapine   since 10  days . He was treated with corticosteroids   , antimicrobial drugs and oral topical anesthetic agents. Health care providers must be careful regarding the adverse effects of drugs especially the allergic manifestations like anaphylaxis and  Steven Johnson syndrome which are potentially fatal conditions. The most commonly and widely prescribed drug regimens should also be used judiciously and continuously monitored to prevent such a fatal adverse drug reaction.

The Perspective of Older Men With Depression on Suicide and Its Prevention in Primary Care

Crisis ◽  
2018 ◽  
Vol 39 (5) ◽  
pp. 397-405 ◽  
Author(s):  
Steven Vannoy ◽  
Mijung Park ◽  
Meredith R. Maroney ◽  
Jürgen Unützer ◽  
Ester Carolina Apesoa-Varano ◽  
...  
Keyword(s):  
Primary Care ◽  
Low Socioeconomic Status ◽  
Thematic Analysis ◽  
Older Men ◽  
Primary Care Providers ◽  
Depression Treatment ◽  
Care Providers ◽  
Low Socioeconomic ◽  
Self Image ◽  
The Impact

Abstract. Background: Suicide rates in older men are higher than in the general population, yet their utilization of mental health services is lower. Aims: This study aimed to describe: (a) what primary care providers (PCPs) can do to prevent late-life suicide, and (b) older men's attitudes toward discussing suicide with a PCP. Method: Thematic analysis of interviews focused on depression and suicide with 77 depressed, low-socioeconomic status, older men of Mexican origin, or US-born non-Hispanic whites recruited from primary care. Results: Several themes inhibiting suicide emerged: it is a problematic solution, due to religious prohibition, conflicts with self-image, the impact on others; and, lack of means/capacity. Three approaches to preventing suicide emerged: talking with them about depression, talking about the impact of their suicide on others, and encouraging them to be active. The vast majority, 98%, were open to such conversations. An unexpected theme spontaneously arose: "What prevents men from acting on suicidal thoughts?" Conclusion: Suicide is rarely discussed in primary care encounters in the context of depression treatment. Our study suggests that older men are likely to be open to discussing suicide with their PCP. We have identified several pragmatic approaches to assist clinicians in reducing older men's distress and preventing suicide.

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