scholarly journals CRIPSR Case System: Biological Role in Bacterial Virulence, Genome Editing and in Antimicrobial Resistance

2021 ◽  
Vol 36 (1) ◽  
Author(s):  
Muhamamd Rizwan ◽  
Muhammad Arshad ◽  
Muhammad Kashif ◽  
Aneela Zameer Durrani ◽  
Asghar Abbas ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Genome Editing ◽  
Bacterial Virulence ◽  
Biological Role ◽  
Case System

scholarly journals An ex vivo lung model to study bronchioles infected with Pseudomonas aeruginosa biofilms

2016 ◽  
Author(s):  
Freya Harrison ◽  
Stephen P. Diggle
Keyword(s):  
Cystic Fibrosis ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Resistance ◽  
Predictive Power ◽  
Ex Vivo ◽  
Opportunistic Pathogen ◽  
Lung Infection ◽  
Bacterial Virulence ◽  
Lung Model ◽  
Physical And Chemical

AbstractA key aim in microbiology is to determine the genetic and phenotypic bases of bacterial virulence, persistence and antimicrobial resistance in chronic biofilm infections. This requires tractable, high-throughput models that reflect the physical and chemical environment encountered in specific infection contexts. Such models will increase the predictive power of microbiological experiments and provide platforms for enhanced testing of novel antibacterial or antivirulence therapies. We present an optimised ex vivo model of cystic fibrosis lung infection: ex vivo culture of pig bronchiolar tissue in artificial cystic fibrosis mucus. We focus on the formation of biofilms by Pseudomonas aeruginosa. We show highly repeatable and specific formation of biofilms that resemble clinical biofilms by a commonly-studied lab strain and ten cystic fibrosis isolates of this key opportunistic pathogen.

Action Urged Against Antimicrobial Resistance

2011 ◽  
Vol 42 (6) ◽  
pp. 26
Author(s):  
KERRI WACHTER
Keyword(s):  
Antimicrobial Resistance

Bacterial epidemiology and antimicrobial resistance in ascitic fluid: A 2-year retrospective study

2009 ◽  
pp. 1-5 ◽  
Author(s):  
Lionel Piroth ◽  
Andre Pechinot ◽  
Anne Minello ◽  
Benoit Jaulhac ◽  
Isabelle Patry ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Antimicrobial Resistance ◽  
Ascitic Fluid

Genome editing: Wollen wir das wirklich?

2017 ◽  
Vol 6 (3) ◽  
pp. 162-162
Author(s):  
Liane Kaufmann ◽  
Michael von Aster
Keyword(s):  
Genome Editing

Research round-up: Antimicrobial resistance

Nature ◽  
2020 ◽  
Vol 586 (7830) ◽  
pp. S58-S59
Author(s):  
Elizabeth Svoboda
Keyword(s):  
Antimicrobial Resistance
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