scholarly journals Correlation of Lipid Profile and Glycated Hemoglobin as a New Prognostic Criterion for Type 2 Diabetes Mellitus Development and Progression

2020 ◽  
Vol 12 (2) ◽  
pp. 87
Author(s):  
E.A. Zagrebin ◽  
E.A. Shevchenko ◽  
E.Yu. Ivanchenko ◽  
V.I. Uspensky ◽  
S.R. Abasnia ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Glycated Hemoglobin ◽  
Prognostic Criterion

scholarly journals Glycated haemoglobin acts as an indicator of dislipidemia in patients with Type II diabetes mellitus

2018 ◽  
Vol 5 (2) ◽  
pp. 185-192
Author(s):  
Sumaia Sahrin ◽  
Dilruba Easmin Jharna ◽  
M Shafiqul Islam Khan ◽  
Jayati Debnath ◽  
Suman Talukder
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Glycated Hemoglobin ◽  
Density Lipoprotein ◽  
Good Glycemic Control

Diabetic patients with associated dyslipidemia are easy targets for cardiovascular diseases (CVD). Glycated hemoglobin predicts the risk for the development of diabetic complications. This study was an attempt to determine lipid abnormalities associated with Type-2 Diabetes Mellitus and association between glycated hemoglobin (HbA1c) levels and serum lipid profile to assess the importance of HbA1c as an indicator of dyslipidemia and future risk of cardiovascular disease in Bhola District, Barisal. In this cross-sectional study, 200 known patients of Type-2 Diabetes Mellitus within 35-85 years of age were randomly selected. They were investigated for HbA1c and lipid profile. The data were evaluated by Statistical Package for Social Sciences (SPSS) 16.0 version software. Independent samples t-test (2-tailed) was used to compare means of anthropometric, clinical and laboratory parameters and the effect of the glycemic control on their lipid profile was determined using correlation coefficient. Amongst the study group, 65% patients showed poor glycemic control, 35% with good glycemic control and 59.60% patient’s haddyslipidemia.HbA1c was found to have significant positive correlation with total cholesterol (TCHO), low density lipoprotein (LDL-C) and triglycerides (TG) and significant negative correlation with high density lipoprotein (HDL-C). The mean value of TC, LDL-C and TG was found to be lower in patients with good glycemic control than those with poor glycemic control. These differences were significant at the level of P<0.05. These findings conclude that the glycemic control of the patient has got a strong impact on the serum lipid level and dyslipidemia is frequently encountered in those who have got poor glycemic control.Res. Agric., Livest. Fish.5(2): 185-192, August 2018

scholarly journals HbA1c as screening biomarker of dyslipidemia in type 2 diabetes mellitus patients

2018 ◽  
Vol 5 (4) ◽  
pp. 969
Author(s):  
S. P. Tejaswi Pullakanam ◽  
Krishna Barla ◽  
Ramakrishna Nekkala ◽  
Pullaiah Pasupeleti
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cardiovascular Diseases ◽  
Lipid Profile ◽  
Glycated Hemoglobin ◽  
Inverse Correlation ◽  
Potential Biomarker

Background: Patients with diabetes are considered to be at high risk for dyslipidemia and hypertension and therefore vulnerable to cardiovascular diseases. This study describes the possible role of Glycated Hemoglobin (HbA1c) and serum lipid profile as a biomarker for detecting cardiovascular diseases. The aim of present work is to study the role of HbA1c as a screening biomarker for dyslipidemia in patients with type 2 Diabetes Mellitus (T2DM).Methods: Present study consists of 100 Type 2 DM patients between age 30-75 years along with age and sex matched 100 healthy controls. Fasting Blood samples were collected from all participants for measuring lipid profile, blood sugar (FBS) and HbA1c.Results: Present study revealed a significantly increased level of glycated hemoglobin (HbA1c) in cases compared to control. HbA1c showed direct and significant correlations with cholesterol, triglycerides and LDL and inverse correlation with HDL in cases when compared to controls.Conclusions: HbA1c can be used as a potential biomarker for the prediction of Dyslipidemia and CVD.

scholarly journals Effect of Anti Diabetic Drugs on Lipid Profile in Patients with Type 2 Diabetes Mellitus

2016 ◽  
Author(s):  
Alaa H. Jawad ◽  
Zyad H. Al-Qaisi ◽  
Ammal E. Ibrahim ◽  
Zainab S. Hallab ◽  
Abdualbasit Graisa ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Metabolic Diseases ◽  
Glycated Hemoglobin ◽  
Favorable Effect ◽  
Control Group ◽  
Lipids Profile

Diabetes mellitus (DM) has been defined as a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. This study includes (84) subjects, their age ranged from (40 to 54) years. (20) subjects were healthy chosen as control group and (64) patients with type 2 diabetes mellitus were divided into three groups according to their type of anti diabetic therapy: (23) newly diagnosed group without therapy (Group1), (20) with metformin therapy (Group2) and (21) with metformin plus glibenclamide therapies (Group3). In the study lipid profile level were quantitatively determine by enzymatic methods, in addition to that fasting plasma glucose (FPG), Glycated hemoglobin (HbA1c%) and body mass index (BMI) were identified in the patients. There is significant increase in the level of lipid profile in patients group. Metformin alone produce a non-significant favorable effect on all lipids profile parameters while metformin plus glibenclamide showed a significant reduction in TC and LDL-C.

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