scholarly journals Virtual embryoscope for detection of structural abnormalities in first trimester pregnancy

2017 ◽  
Vol 6 (5) ◽  
pp. 1924
Author(s):  
Sumesh Choudhary ◽  
Vineet Mishra ◽  
Rohina Aggarwal
Keyword(s):  
First Trimester ◽  
3D Ultrasound ◽  
P Value ◽  
Detection Rates ◽  
Significant Difference ◽  
Structural Abnormalities ◽  
Innovative Tool ◽  
2D Ultrasound ◽  
Additional Value ◽  
A Prospective Study

Background: To determine whether there is an additional value of virtual embryoscopy with 3Dimensional (3D) ultrasound above (2D) ultrasound regarding detection rates of structural abnormalities in first trimester pregnancy.Methods: This was a prospective study consisting of 52 pregnant women with gestational age ranging from 6 to 12 weeks. 2D and 3D ultrasound scan was performed using GE voluson E8 transvaginal probe. All scans were evaluated by ten gynecologists trained in USG. The observations were noted and compared for anatomical details and detection of structural defects.Results: It was found that images were seen well with 3D (virtual embryoscope). i.e. maximum count 19 in the table and there is statistically significant difference between 3D and 2D images with a p-value <0.01 at 95% confidence interval (CI).Conclusions: Virtual embryoscope is an innovative tool for evaluation of developing embryo and early foetal morphology. The advantages are the ability to reconstruct 3D images with the stored scanned volume and examine without having to rescan the patient.

Impact of Including or Removing Nuchal Translucency Measurement on the Detection and False-Positive Rates of First-Trimester Down Syndrome Screening

2015 ◽  
Vol 40 (3) ◽  
pp. 214-218 ◽  
Author(s):  
Emmanuel Spaggiari ◽  
Isabelle Czerkiewicz ◽  
Corinne Sault ◽  
Sophie Dreux ◽  
Armelle Galland ◽  
...  
Keyword(s):  
Down Syndrome ◽  
False Positive ◽  
False Positive Rate ◽  
Method Comparison ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Routine Practice ◽  
Detection Rates ◽  
Significant Difference ◽  
Positive Rate

Introduction: First-trimester Down syndrome (DS) screening combining maternal age, serum markers (pregnancy-associated plasma protein-A and beta-human chorionic gonadotropin) and nuchal translucency (NT) gives an 85% detection rate for a 5% false-positive rate. These results largely depend on quality assessment of biochemical markers and of NT. In routine practice, despite an ultrasound quality control organization, NT images can be considered inadequate. The aim of the study was to evaluate the consequences for risk calculation when NT measurement is not taken into account. Material and Method: Comparison of detection and false-positive rates of first-trimester DS screening (PerkinElmer, Turku, Finland), with and without NT, based on a retrospective study of 117,126 patients including 274 trisomy 21-affected fetuses. NT was measured by more than 3,000 certified sonographers. Results: There was no significant difference in detection rates between the two strategies including or excluding NT measurement (86.7 vs. 81.8%). However, there was a significant difference in the false-positive rates (2.23 vs. 9.97%, p < 0.001). Discussion: Sonographers should be aware that removing NT from combined first-trimester screening would result in a 5-fold increase in false-positive rate to maintain the expected detection rates. This should be an incentive for maintaining quality in NT measurement.

scholarly journals P03.10: First trimester detection of structural abnormalities; a comparison of 2D/3D ultrasound and virtual embryoscopy

2012 ◽  
Vol 40 (S1) ◽  
pp. 180-181
Author(s):  
L. Baken ◽  
M. Rousian ◽  
A. H. Koning ◽  
G. J. Bonsel ◽  
E. Steegers ◽  
...  
Keyword(s):  
First Trimester ◽  
3D Ultrasound ◽  
Structural Abnormalities

scholarly journals Conventional incision and drainage versus incision and drainage with primary closure in acute abscess: a prospective study

2017 ◽  
Vol 5 (1) ◽  
pp. 281
Author(s):  
Amandeep Singh ◽  
Gurdhian Singh ◽  
Darsshan Singh Sidhu ◽  
Mohit Bhalla
Keyword(s):  
Wound Healing ◽  
Hospital Stay ◽  
Recurrence Rate ◽  
Conventional Method ◽  
Primary Closure ◽  
The Body ◽  
P Value ◽  
Incision And Drainage ◽  
Significant Difference ◽  
A Prospective Study

Background: An abscess is a common surgical condition. Abscesses may occur anywhere in the body. Surgical treatment of subcutaneous and soft tissue abscesses includes percutaneous aspiration, incision and drainage without primary closure, incision and drainage with primary closure with drain. The present study was planned to compare conventional method of incision and drainage with incision and drainage with primary closure in cases of acute -abscesses.Methods: A total of 100 patients with acute abscesses were included in the study and randomized into 2 groups with 50 patients in each group. The present study was carried out to compare the conventional method of incision and drainage with incision and drainage with primary closure of the wounds in acute abscesses with regards to wound healing, post- operative pain, duration of hospital stays and recurrence rates.Results: Wound healing was significantly faster in incision and drainage with primary closure (9.18±0.941days) as compared to conventional method of incision and drainage (16.66±1.944 days) [p <0.05]. Mean hospital stay with convention method of incision and drainage was 7.12±0.718 days and with primary closure was 4.0±0.728days (p <0.05). Mean VAS was significantly less in primary closure as compared with conventional method. Decreasing trend in VAS was observed on day 3, day 5 and day 7 (p value 0.000). Recurrence rate of an abscess was seen in 5 cases in conventional method and 2 cases in primary closure (p >0.05).Conclusions: Author have observed a significant difference noted in time taken for wound healing, postoperative pain, hospital stay and recurrence rate between two groups.

scholarly journals C-reactive protein/albumin ratio as a predictor of 28 day mortality in patients with sepsis

2020 ◽  
Vol 8 (2) ◽  
pp. 503
Author(s):  
Hamsa B. T. ◽  
Srinivasa S. V. ◽  
Raveesha A.
Keyword(s):  
Inotropic Support ◽  
Secondary Outcome ◽  
P Value ◽  
C Reactive Protein ◽  
Albumin Ratio ◽  
Reactive Protein ◽  
Significant Difference ◽  
Life Threatening ◽  
Sepsis And Septic Shock ◽  
A Prospective Study

Background: Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis remains a major cause of morbidity and mortality worldwide. Important biomarkers that can be used as prognostic markers in sepsis are C Reactive Protein (CRP) and serum Albumin levels. CRP levels markedly elevate in response to infection whereas albumin levels decrease in response to acute phase infection. We want to ascertain the value of CRP/albumin ratio as an independent predictor of 28-day mortality in sepsis patients.Methods: A prospective study was conducted including 150 patients satisfying the criteria for sepsis according to SOFA score of more than 2. Initial CRP/Albumin ratio was assessed to determine its significance in assessing the 28-day mortality, primary end point of our study. Secondary end points assessed were length of ICU stay, need for inotropic support, need for ventilator support and renal replacement therapy.Results: In the analysis of CRP/Albumin ratio as a predictor of 28-day mortality, patients were followed up from day of admission till 28 days to assess primary outcome. Among study subjects survivors were 92 in whom mean CRP/ALB ratio was 0.1197 and non survivors were 58 patients with mean CRP/ALB ratio was 0.0426. p-value <0.001, there was statistically significant difference found between survivor and Non-Survivor with respect to CRP/Albumin ratio. In assessing secondary outcome statistically significant association was found for need for ventilator and inotropic support, whereas it was insignificant in assessing need for dialysis and length of ICU stay.Conclusions: CRP/albumin ratio, which indicates the extent of residual inflammation, could be used as a prognostic marker in predicting mortality in patients with sepsis and septic shock.

scholarly journals Risk Factors and Outcome of Neonatal Thrombocytopenia

2020 ◽  
Vol 24 (3) ◽  
pp. 229-234
Author(s):  
Hira Arif ◽  
Nadeem Ikram ◽  
Shangraf Riaz ◽  
Asma Nafisa
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Neonatal Intensive Care ◽  
Birth Asphyxia ◽  
P Value ◽  
Maternal Risk ◽  
Significant Difference ◽  
Neonatal Thrombocytopenia ◽  
A Prospective Study

Introduction: About 30% of neonates develop thrombocytopenia during hospital admission. Inevitable and irreversible complications can be prevented by determining the risk factors of neonatal thrombocytopenia. The present study was undertaken to determine the risk factors and outcome of neonatal thrombocytopenia in neonates admitted to Neonatal Intensive Care Unit Benazir Bhutto Hospital Rawalpindi. Materials and Methods: A prospective study was conducted to evaluate the risk factors for neonatal thrombocytopenia (NT) in 160 neonates. Neonatal and maternal risk factors were recorded and neonates were categorized into three groups based on the severity of thrombocytopenia. Results: A higher percentage of the neonates 89 (55.6%) were male. The majority (61.9%) had moderate neonatal thrombocytopenia while 21.9% had severe neonatal thrombocytopenia. A highly significant difference was observed for the distribution of gestational age, platelet count, birth weight, and age at admission (for all p-value ≥0.0001) among different groups. Multivariate logistic regression revealed a significant independent association of prematurity, birth asphyxia, and low birth weight with neonatal thrombocytopenia. Conclusion: Prematurity, low birth weight, and birth asphyxia were the significant causes of Neonatal thrombocytopenia. The mortality rate increased significantly with the severity of thrombocytopenia.

A Prospective Study Comparing Cancer Detection Rates of Transperineal Prostate Biopsies Performed by Junior Urologists Versus a Senior Consultant in a Real World-setting

2020 ◽  
Author(s):  
Jiaao Song ◽  
Bi-ming He ◽  
Hu-sheng Li ◽  
Zhen-kai Shi ◽  
Guan-yu Ren ◽  
...  
Keyword(s):  
Specific Antigen ◽  
Daily Practice ◽  
Secondary Outcome ◽  
Complication Rates ◽  
Detection Rates ◽  
Prostate Biopsies ◽  
Significant Difference ◽  
Procedural Time ◽  
Practice Method ◽  
A Prospective Study

Abstract Background: Prostate biopsy (PB) is a typical daily practice method for the diagnosis of prostate cancer (PCa). This study was to compare the PCa detection rate and peri- and post-operative complications of PB among three residents and a consultant.Methods: A total of 343 patients who underwent PB between August 2018 with July 2019 were involved in this study. Residents were systematically trained two weeks by the consultant for performing systemic biopsy (SB) and targeted biopsy (TB). And then, three residents and the consultant performed PB independently every quarter due to routine rotation in daily practice. The peri- and post-operative data was prospectively collected. The primary outcome and secondary outcome were to compare the PCa-detection rates and complications between residents and consultant, respectively. Results: There was no significant difference between the residents and consultant in terms of overall PCa-detection rates of SB, TB or further stratified by prostate specific antigen value, prostate imaging reporting and data system (PI-RADS) scores. We found the consultant had more TB cores compared with residents (175 cores versus 86 to 114 cores, P=0.043) and shorter procedural time versus residents (mean 16 min versus 19.7 to 20.1 min, P <0.001). The complication rate for consultant was 6.7%, and 5% to 8.2% for residents, respectively (P = 0.875).Conclusions: The residents could get a similar PCa detection and complication rates compared with the consultant after a two-week training. However, the residents still need more cases to shorten the time of biopsy procedure.

Diagnosis of cleft lip-palate during nuchal translucency screening – case report and review of the literature

2012 ◽  
Vol 1 (1-2) ◽  
Author(s):  
Ashwin R. Jadhav ◽  
Ana Monteagudo ◽  
Rosalba Santos ◽  
Ilan Timor
Keyword(s):  
Cleft Palate ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
First Trimester ◽  
Nuchal Translucency ◽  
3D Ultrasound ◽  
Ultrasound Screening ◽  
Aneuploidy Screening ◽  
Detection Rates ◽  
Cleft Lip Palate

AbstractOrofacial clefts are the most common group of craniofacial anomalies. The detection rate of cleft lip during the mid-trimester, using two-dimensional (2D) ultrasound screening, has improved over the last three decades. However, the detection rates of defects involving the hard palate or isolated cleft palate have remained poor. Over the last decade, many investigators have studied the use of 3D ultrasound to improve the detection rates of these defects. With the increasing use and acceptance of first-trimester aneuploidy screening in the US, there is growing interest in performing first-trimester fetal anatomy surveys. Reports of first-trimester diagnosis of cleft lip and palate are rare, and this aspect of prenatal sonographic diagnosis remains underexplored. We report a case of unilateral cleft lip and cleft palate diagnosed during a routine first-trimester screening at 12 weeks’ gestation and review the pertinent literature on first-trimester diagnosis of cleft lip/palate.

scholarly journals ROLE OF SEPTOPLASTY AND FUNCTIONAL ENDOSCOPIC SINUS SURGERY IN THE TREATMENT OF RHINOGENIC HEADACHE

2021 ◽  
Vol VOLUME 9 (ISSUE 1) ◽  
pp. 6-12
Keyword(s):  
Chronic Rhinosinusitis ◽  
Endoscopic Sinus Surgery ◽  
Functional Endoscopic Sinus Surgery ◽  
Sinus Surgery ◽  
Nasal Endoscopy ◽  
P Value ◽  
Age Group ◽  
Significant Difference ◽  
Key Factor ◽  
A Prospective Study

INTRODUCTION: Rhinogenic headaches are basically described as headache or facial pain caused by rhinological source. The presence of nasal symptoms & it’s temporal relationship with headache is the key factor that can guide the diagnosis and patient management. AIMS: This study aims to evaluate the efficacy of Septoplasty with Functional endoscopic sinus surgery (F.E.S.S) in the management of Rhinogenic headache. MATERIALS & METHODS: It was a Prospective study conducted in M.G.M Medical College & associated M.Y group of hospitals from March 2019 to March 2020. 64 patients of age group 18 years to 60 years having chronic rhinosinusitis with headache included in the study. After detailed history and thorough examination, nasal endoscopy and CT Paranasal sinus was done. Patients not responding to conservative management were selected for undergoing functional endoscopic sinus surgery. RESULTS: A total of 64 patients were included in the study,34 male & 30 female with the mean age group of 31.4 & 30.1 years respectively. Out of 64 patients,67% were completely free from headache,15% were significantly improved,7% had mild relief & 11% did not show any benefit in headache from surgery. Postoperatively, there was statistically significant difference was found patient’s symptomatology (i.e. p value =0.0165). CONCLUSION: To make the diagnosis both anatomical & infective factors needed to be considered. Correction of obvious anatomic abnormalities in carefully selected patients can significantly improve several important clinical outcomes from abolishing headache completely to decreasing its intensity and frequency of episodes. KEY-WORDS: Rhinogenic headaches, Septoplasty, Chronic rhinosinusitis, F.E.S.S, Nasal endoscopy

IMPACT OF ULTRASOUND AND SOCIODEMOGRAPHIC VARIABLES ON MATERNAL FOETAL ATTACHMENT IN TARABA STATE, NIGERIA

2021 ◽  
Vol 35 (1) ◽  
pp. 25-34
Author(s):  
A Yakubu
Keyword(s):  
Sampling Method ◽  
Unplanned Pregnancy ◽  
Sociodemographic Factors ◽  
P Value ◽  
Psychological Benefits ◽  
Income Status ◽  
Significant Difference ◽  
Planned Pregnancy ◽  
Socio Demographic Factors ◽  
A Prospective Study

Background: Maternal foetal attachment is manifested in behaviours that demonstrate care and commitment to the foetus. Ultrasound decreases maternal anxiety and confers psychological benefits following a reassuring sonogram. Maternal-foetal attachment is affected by many socio-demographic factors which include maternal age, occupation, educational level, race, marriage duration, ethnicity, Religion, income status, pregnancy planning, and identification of the foetal gender Aim: This study was aimed at assessing the effect of ultrasound and sociodemographic factors on maternal foetal attachment during pregnancy. Method: A prospective study was conducted from November 2019 to March 2020. A convenient sampling method was employed and included 404 pregnant women aged 18-45 years old in their 2nd and 3rd trimesters. The data were collected using a maternal foetal attachment scale questionnaire. Descriptive and inferential statistics were carried out at a p-value < 0.05. Result: The score of the maternal foetal attachment scale was greater with post ultrasound than the pre ultrasound. There was a statistically significant difference between the pre and post ultrasound maternal foetal attachment scale (p=0.000). A statistically significant difference was observed in the maternal foetal attachment across the different ethnic groups (p=0.000), planned and unplanned pregnancy (p=0.000). Conclusion: This study revealed that ultrasound scan has an influence on maternal foetal attachment, planned pregnancy. Hausa, Bandawa and Jenjo were found to be more attached to their foetuses.

scholarly journals Perbedaan Kunjungan Pertama Ibu Hamil Berdasarkan Usia di Poskesdes Wilayah Kerja UPTD Puskesmas Gunungsari Kabupaten Lombok Barat

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Kusniyati Utami ◽  
Irni Setyawati
Keyword(s):  
Maternal Mortality ◽  
Pregnant Women ◽  
Health Workers ◽  
Sampling Technique ◽  
First Trimester ◽  
P Value ◽  
Antenatal Visit ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference

The West Nusa Tenggara Provincial Health Office (2017) mentions the number of maternal mortality from 2015 to 2017 continues to decrease, from 95 cases to 85 cases. Maternal mortality during pregnancy can be prevented by antenatal care by health workers in accordance with the frequency of antenatal visits a minimum of four times. The first visit is carry out at a gestational age of the mother <16 weeks (Ministry of Health Republic of Indonesia, 2013), but still found pregnant women who made the first antenatal visit in the second trimester and even the third trimester.The purpose of this study was to determine the differences in first visit of pregnant women by age in the Poskesdes working area of the UPTD Puskesmas Gunungsari.This study used a cross-sectional analytic research design in eight Poskesdes in the working area of the UPTD Puskesmas Gunungsari, West Lombok district in November 2018 to January 2019. Samples were taken using a total sampling technique of 1042 people.Secondary data was collected from the maternal cohort register in eight Poskesdes in the UPTD Puskesmas Gunungsari working area in the form of the age of the mother at the first visit and the age of the mother's pregnancy at the first visit. Data were processed univariately and bivariately using the chi-square test.There was a significant difference in the first visit of pregnant women between mothers aged <20 years, 20-35 years, and> 35 years as indicated by the p value of 0.00001 (<0.05). It is expected that midwives in Poskesdes will further enhance the role of cadres in capturing first trimester pregnant women especially those aged <20 years and> 35 years.

Sign in / Sign up

Export Citation Format

Share Document