scholarly journals Study of maternal deaths with COVID-19 infection in a tertiary care centre

2021 ◽  
Vol 11 (1) ◽  
pp. 74
Author(s):  
Niranjan Chavan ◽  
Shikhanshi . ◽  
Deepali Kapote ◽  
Prasad Deshmukh ◽  
Ashwini Sakhalkar
Keyword(s):  
Maternal Mortality ◽  
Tertiary Care ◽  
Health Sector ◽  
Tertiary Referral Hospital ◽  
Tertiary Care Centre ◽  
Susceptible Population ◽  
Medical College ◽  
Co Morbidity ◽  
Substantial Risk

Background: COVID-19 has been a major speed braker not only for world economy and development but also for health sector. The susceptible population including elderly, co-morbid adults and pregnant females were likewise affected in both major COVID-19 waves in India. Association between COVID-19 cases and pregnancy has been studied throughout the world.COVID-19 is associated with substantial risk of morbidity and mortality in postpartum patients and their infants world-wide, compared with their not-infected pregnant counter-parts, especially if these individuals were symptomatic or have comorbidities.Methods: This single-centre prospective observational study, included all consecutive maternal mortalities with COVID-19 infection admitted to Lokmanya Tilak municipal medical college and general hospital (Mumbai, India), a tertiary referral hospital, from 1 April 2020, to June 2021.In this study, a total of 390 patients were included who were found COVID-19 positive during the study period and 17 patients who died during their admission in hospital. The relation of risk factors and demographics were studied for all the patients.Results: The COVID-19 related maternal mortality was more in women of age group 20-30 years (89%). Most women presented to our centre with complaints of fever, cough, cold or breathlessness (55.5%). Patients who succumbed to COVID-19 were mostly primiparous patients (52.9%) and died within 5 days of delivery (46%). 64% of patients died following 5 days of diagnosis of COVID-19.The co-morbidity present in most patients with COVID-19 associated maternal mortality was pre-eclampsia (31.5%). Most patients were referred with only 17% patients registered at our centre and the type of delay involved in management was mostly Type 1 and 2 (82.2%)Conclusions: Multi-centre retrospective analysis with larger population size is required in order for this to be statistically significant.

scholarly journals Maternal mortality-a three-year retrospective study in a rural medical college of India

2021 ◽  
Vol 10 (8) ◽  
pp. 3019
Author(s):  
Jayasree Hansda ◽  
Debobroto Roy ◽  
Krishnapada Das ◽  
Manojit Sarkar ◽  
Rumpa Das ◽  
...  
Keyword(s):  
Maternal Mortality ◽  
Maternal Death ◽  
Tertiary Care ◽  
Maternal Mortality Ratio ◽  
Tertiary Care Centre ◽  
Maternal Deaths ◽  
Demographic Profiles ◽  
Medical College ◽  
Mortality Ratio ◽  
Tragic Event

Background: Maternal mortality is a tragic event as family revolves around a mother. The deadly obstetrical triad of hemorrhage, preeclampsia and infection has accounted for a third of all deaths. This study was conducted to assess maternal mortality ratio, demographic profile and causes of maternal death.Methods: This retrospective longitudinal study was conducted in the department of obstetrics and gynecology for a period of three years from 1st January 2018-31st December, 2020. Total no of death during this period was 134.Records of deaths and demographic profiles were retrieved from the medical record library of aforesaid hospital.Results: There were 134 maternal deaths amongst 56815 live births with MMR 235.85. The majority of deaths were in 20-29 year of age group and most of the deaths seen in multigravida. The 91.79% death was observed within the 24 hours and after 72 hours. Eclampsia, preeclampsia and hemorrhage were leading cause of maternal death seen in the study.Conclusions: Maternal mortality is higher than national MMR. Majority of maternal death were preventable by proper antenatal care, early detection of high-risk pregnancies and their timely referral to tertiary care centre.

scholarly journals EVALUATE THE DIRECT AND INDIRECT ETIOLOGIES OF MATERNAL MORTALITY: A RETROSPECTIVE ANALYSIS.

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Rashmi Kumari ◽  
Usha Kumari ◽  
Krishna Sinha
Keyword(s):  
Maternal Mortality ◽  
Maternal Death ◽  
Tertiary Care ◽  
Tertiary Care Centre ◽  
Maternal Deaths ◽  
Medical College ◽  
Multiparous Women ◽  
Jawaharlal Nehru ◽  
Primiparous Women ◽  
Timely Referral

Aim: prevalence and the various direct and indirect etiologies of maternal mortality. Materials and Methods: The present 1 years retrospective hospital based study was conducted in the Department of Obstetrics and Gynecology, Jawaharlal Nehru Medical College and Hospital, Bhagalpur,Bihar,India Results: A total of 56 deaths were analyzed. The mortality rate in study period was 333 per 1,00,000 live births. Maximum maternal deaths (60.7%) were reported in the age group 21-25 years. More deaths were reported in multiparous women (67.9%) as compared to primiparous women (32.1%). Most of them were unbooked cases (60%). Hemorrhage (30.4%), eclampsia (16.1%), sepsis (12.5%) and embolism (7.1%) were the major direct causes of maternal death. Anemia (16.1%) was the major indirect cause of death. Conclusions: Hemorrhage is the leading cause of maternal death followed by hypertensive disorders and sepsis. Anemia continues to be the most common indirect cause. Majority of maternal deaths were preventable by proper antenatal care, early detection of high risk pregnancies and their timely referral to tertiary care centre. Keywords: MMR, Hemorrhage, Sepsis, Anemia

scholarly journals A Comparative Study of CURB-65 and Expanded CURB-65 Scoring Systems in Community Acquired Pneumonia in a Tertiary Care Centre of Patna

2021 ◽  
Vol 8 (16) ◽  
pp. 1074-1078
Author(s):  
Debjit Mitra ◽  
Uttiya Roy ◽  
Abhay Kumar Sinha ◽  
Shiv Shankar Bharti
Keyword(s):  
Mechanical Ventilation ◽  
Mortality Rate ◽  
Scoring System ◽  
Tertiary Care ◽  
Community Acquired Pneumonia ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Co Morbidity ◽  
Significant Difference

BACKGROUND A variety of organisms cause community-acquired pneumonia, including bacteria, viruses and fungi. Pathogens vary in age and other factors, but the relative importance of each pneumonia as a cause of community-acquired pneumonia remains uncertain because most patients do not undergo thorough testing and because even when tested, specific agents are found in < 50 percent of cases. This study was conducted to evaluate a severity scoring system for community acquired pneumonia and compare it with the standard confusion, urea, respiratory rate, blood pressure and 65 years of age or older (CURB-65) scoring system in a tertiary care centre in Patna Medical College. METHODS This hospital based prospective study was conducted among 100 consecutive patients of community-acquired pneumonia (CAP) attending OPD or getting admitted in General Medicine ward of Patna Medical College. The CURB-65 and Expanded CURB-65 scores for these patients were calculated and the accuracy of either in predicting outcomes was statistically analysed, during the period September 2018 - May 2019. RESULTS The mean age of CAP patients in our study was 59.09 ± 12.942 years, the most common co-morbidity observed was diabetes mellitus followed by chronic obstructive pulmonary disorders (COPD), cardiovascular disease, chronic liver disease and chronic renal disease. Our study showed that the mortality rate of the study population was 12 % and 30 % patients needed admission in the ICU and 24 % patients needed invasive mechanical ventilation. In the above analysis for 30-day mortality rate, ICU admission rate, and the need for mechanical ventilation among 0 - 2 and 3 - 5 CURB 65 scores, we found no statistically significant difference (P-value = > 0.05). CONCLUSIONS The extended CURB-65 score gives priority to both clinical and laboratory parameters and is a more accurate marker for the evaluation of CAP severity and may boost the effectiveness of predicting mortality in CAP patients compared to the current CURB-65 score system. KEYWORDS CAP, CURB-65, Expanded CURB-65

scholarly journals Changing trends of maternal mortality with its causes- ten years retrospective study in a peripheral medical college of West Bengal, India

2021 ◽  
Vol 10 (4) ◽  
pp. 1649
Author(s):  
Anjan Dasgupta ◽  
Abirbhab Pal ◽  
Nikita . ◽  
Debanjana Dasgupta ◽  
Partha Ghosh
Keyword(s):  
Maternal Mortality ◽  
Maternal Death ◽  
Health Care Services ◽  
West Bengal ◽  
Tertiary Care ◽  
Maternal Mortality Ratio ◽  
Total Sample ◽  
Hypertensive Disorder ◽  
Tertiary Care Centre ◽  
Medical College

Background: The estimates of maternal mortality can only be used as a rough indicator of maternal health situation in any given country. High maternal mortality reflects not only in inadequacy of health care services for mothers, but also a low standard of living and socio economic status of the community. Objective was to assess the maternal mortality ratio (MMR), its probable causes and changing trends.Methods: The present study conducted at Midnapore Medical College (MMC), West Bengal. Data for analysis were collected from medical college record section and maternal death registrar book after having permission from higher authority of the college during the period from January 2009 to 2018 December. Total sample size for this period was 249. Statistical analysis was done through SPSS software.Results: Ten years data analysis of 249 subjects showed that total live births from January 2009 to December 2018 was 1,39,126 with MMR 178.97%. Hypertensive disorder of pregnancy (40.56%) was the leading direct cause of maternal death followed by hemorrhage (24.49%) and septicemia (10.84%). Heart disease (6.42%) was the major indirect cause of death followed by anemia (3.6%). Maternal death rate found high among primi gravida (59.43%) mothers and within 20 years age group (46.18%).Conclusions: Most maternal deaths are preventable by proper antenatal care, early diagnosis of high risk factors, timely referral to tertiary care centre along with community upliftment especially in rural and tribal based population. 

scholarly journals EVALUATE THE EXISTING MMR AND THE ETIOLOGY OF MATERNAL MORTALITY IN A TERTIARY CARE HOSPITAL IN BIHAR: A RETROSPECTIVE ANALYSIS.

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Sweety Rani ◽  
Abha Rani Sinha
Keyword(s):  
Maternal Mortality ◽  
Maternal Death ◽  
Tertiary Care ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Maternal Deaths ◽  
Medical College ◽  
Multiparous Women ◽  
Primiparous Women ◽  
Timely Referral

Aim: to assess the existing MMR and the causes of maternal mortality. Materials and Methods: The present retrospective hospital based study was conducted in the Department of Obstetrics and Gynecology, Patna Medical College and Hospital, Patna, Bihar from Jan 2017 to march 2018. Results: A total of 56 deaths were analyzed. The mortality rate in study period was 333 per 1,00,000 live births. Maximum maternal deaths (60.7%) were reported in the age group 21-25 years. More deaths were reported in multiparous women (67.9%) as compared to primiparous women (32.1%). Most of them were unbooked cases (60%). Hemorrhage (30.4%), eclampsia (16.1%), sepsis (12.5%) and embolism (7.1%) were the major direct causes of maternal death. Anemia (16.1%) was the major indirect cause of death. Conclusions: Hemorrhage is the leading cause of maternal death followed by hypertensive disorders and sepsis. Anemia continues to be the most common indirect cause. Majority of maternal deaths were preventable by proper antenatal care, early detection of high risk pregnancies and their timely referral to tertiary care centre. Keywords: MMR, Hemorrhage, Sepsis, Anemia

scholarly journals Study of malaria and associated co-morbidity in children admitted with fever manifestation in a tertiary care centre

2020 ◽  
Vol 7 (8) ◽  
pp. 1705
Author(s):  
Pawan Ghanghoriya ◽  
Rahul Borkar ◽  
Monica Lazarus ◽  
Manish Ajmariya
Keyword(s):  
Severe Malaria ◽  
Severe Acute Malnutrition ◽  
Care Center ◽  
Tertiary Care ◽  
Febrile Illness ◽  
Acute Malnutrition ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Co Morbidity

Background: Children under five year of age are highly vulnerable to malaria infection and often face dire consequences such as severe malaria if they are not promptly and adequately treated with anti-malarial medications. Authors set out to evaluate malaria and associated co-morbidity among children admitted with febrile illness in tertiary care center NSCB Medical college Jabalpur, India.Methods: This prospective and analytic study focused on children admitted with fever in pediatric unit of N.S.C.B. Medical College, Jabalpur, Madhya Pradesh, India. If any co-morbidity present with malaria their manifestation was noted. Association of co-morbidity with malaria was done, and effect of co-morbidity on severity of malaria and outcome of patients was noted.Results: A total number of 1950 of children suspected to have malaria who were tested by RDT and microscopy (PSMP), out of them 100 children were positive. Mean age calculated was 7.3±4.3 years. Maximum number of severe malaria cases (40.6%) were found in 6 months to <5 years age group. Most common co-morbidity associated with malaria was anemia (53%) followed by pneumonia (36%) hepatitis (26%), diarrhea (24%), enteric fever (15%), septicemia and meningoencephalitis (10%) each, UTI (4%), and AKI (6%), while dengue (3%) and severe acute malnutrition (2%). Out of 69 cases of severe malaria 46.3% cases had two and 34.7% cases had more than two co-morbidities while in 31 cases of uncomplicated malaria 38.7% cases had two co-morbidity and only 3% had more than two co-morbidity.Conclusions: All RDT positive cases have associated co-morbidity with malaria in our study, more is the co-morbidity is longer were the duration of stay and higher the complications and even mortality. 

scholarly journals Peripartum hysterectomy: a five year review at a tertiary care centre

2017 ◽  
Vol 6 (8) ◽  
pp. 3590
Author(s):  
Deepak A. V. ◽  
K. J. Jacob ◽  
Sumi P. Maria
Keyword(s):  
Tertiary Care ◽  
Case Series ◽  
Case Fatality ◽  
Tertiary Care Centre ◽  
Retrospective Case ◽  
College Hospital ◽  
Peripartum Hysterectomy ◽  
Medical College ◽  
Obstetric Haemorrhage ◽  
Suboptimal Care

Background: Peripartum hysterectomy is a life-saving procedure resorted to when conservative measures fail to control obstetric haemorrhage. Several predisposing factors, suboptimal care and lack of infrastructure may lead to this emergency procedure. We wanted to find out factors associated with peripartum hysterectomy and the adverse maternal outcomes at our centre.Methods: A retrospective case series analysis of 40 cases of peripartum hysterectomy performed over a period of 5 years from January 2010 to December 2014 at Government Medical College Hospital, Thrissur, Kerala was done.Results: The incidence of peripartum hysterectomy was 0.29%. The most common indication for peripartum hysterectomy was hysterectomy was uterine atony (50%). Thirty-five women (88%) were between 20 and 35 years. Most of the subjects were unbooked. There were two maternal deaths (case fatality rate of 5%) following peripartum hysterectomy during this period. All the subjects required blood transfusion.Conclusions: Prompt performance hysterectomy before the patient’s clinical condition deteriorates is the key to success. The incidence of adherent placenta is increasing, so every effort should be taken to reduce the caesarean section rates globally. 

HISTOPATHOLOGICAL EVALUATION OF WHO CLASSIFIED MULTIBACILLARY LEPROSY CASES IN A TERTIARY CARE CENTRE, SOUTH KERALA

2021 ◽  
pp. 32-34
Author(s):  
Anita Sanker ◽  
G Nandakumar ◽  
Swapna Balkrishnan
Keyword(s):  
Immune Response ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Newly Diagnosed ◽  
Epithelioid Cells ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Leprosy Patients ◽  
Epidermal Atrophy ◽  
Multibacillary Leprosy

There are signicant differences in the histopathology of leprosy lesions which is inuenced by the host immune response to Mycobacterium leprae. Objective - To nd the histopathological changes in newly diagnosed multibacillary leprosy(MB) cases registered in the skin department Government Medical College, Thiruvananthapuram. Method- skin biopsy performed in 40 multibacillary leprosy cases and histopathological ndings were evaluated. 70% showed epidermal atrophy. Granulomas, composed of sheets of foamy macro Results- phages, lymphocytes and epithelioid cells, were seen in 21 cases & twenty two cases were AFB positive. Eight cases each were lepromatous, borderline tuberculoid, mid boderline, borderline lepromatous types. Conclusion- Presence of 60% cases of borderline leprosy indicates the unstable immune response in leprosy patients. Majority were either borderline lepromatous or lepromatous showing the infective nature of multibacillary leprosy. Histopathological examination with Fite- Foroco staining is a crucial method and the gold standard for accurate diagnosis and typing of leprosy.

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