scholarly journals A prospective study of analysis of Cord blood gas to predict the short term outcome in high-risk deliveries

Author(s):  
Ramisetty Uma Mahesh ◽  
Vishnu Vandana Matli

Background: Neonatal acidaemia at birth will increase the neonatal morbidity and mortality. It is a predictive marker of neonatal asphyxia. The current study aimed to investigate the relationship between cord blood gas analysis and neonatal outcome.Methods: A prospective hospital based observational study conducted in 150 term newborns. Cord Blood gas levels were examined, pH of 7.25 was observed in 70 samples. The primary outcomes measured were the percentage of NICU admission, need for resuscitation, convulsions, and encephalopathy.Results: Primary outcome of NICU admission, need for resuscitation, and delay in attaining full feeds were observed to have statistical significance. The majority of the babies had pH levels that were within the normal range and had a healthy outcome. NICU admission and the need for resuscitation were observed in babies from group with acidic pH (<7.25).Conclusions: Cord blood analysis had prognostic significance in predicting outcomes in the new-born period.  

2005 ◽  
Vol 25 (9) ◽  
pp. 615-615
Author(s):  
Michael G Ross

1996 ◽  
Vol 175 (3) ◽  
pp. 517-522 ◽  
Author(s):  
Thorp ◽  
Dildy ◽  
Yeomans ◽  
Meyer ◽  
Parisi

Midwifery ◽  
1996 ◽  
Vol 12 (3) ◽  
pp. 146-150 ◽  
Author(s):  
Maureen Harris ◽  
Sarah L. Beckley ◽  
Jonathan M. Garibaldi ◽  
Robert D.F. Keith ◽  
Keith R. Greene

2019 ◽  
Vol 36 (14) ◽  
pp. 1481-1484
Author(s):  
Megan Whitham ◽  
Jayson Pagaduan ◽  
Steven L. Clark ◽  
Ila Singh ◽  
Michael Belfort ◽  
...  

Objective The calculation of HCO3 and base excess in current blood gas analysis is based on the Siggaard–Andersen equation. One of the constants in this equation is dependent on the known buffering capacity of hemoglobin A. We sought to investigate differences in buffering capacity between adult hemoglobin A and fetal hemoglobin F as a potential explanation for the observed poor correlation between calculated base excess in umbilical cord blood and newborn outcomes. Such differences would influence a key constant in the Van Slyke/Siggaard–Andersen equation used to calculate HCO3 and base excess and could be an explanation of these observations. Study Design This was a prospective observational study. We analyzed umbilical cord blood bicarbonate levels both as calculated values from a traditional blood gas analyzer and as measured values in 20 women giving birth at term. Since the calculated value is dependent upon the concentration and known buffering capacity of hemoglobin A, significant differences in these two analyses would imply differences in the buffering capacity of hemoglobins A and F. Results The mean calculated HCO3 value was 25 mEq/L (25.3 ± 1.9) compared with a mean measured value of 25 mEq/L (24.6 ± 1.7) over a range of pH levels of 7.16 to 7.42. This difference was not significant (p = 0.07). Conclusion The buffering capacity of hemoglobin F, for clinical purposes, is not different than that of hemoglobin A and is not an explanation for the recognized poor correlation between base excess and neonatal outcome.


2019 ◽  
Vol 299 (3) ◽  
pp. 719-724 ◽  
Author(s):  
Jiachen Tang ◽  
Rachel Fullarton ◽  
Sheri-Lee Samson ◽  
Yu Chen

2016 ◽  
Vol 106 (1) ◽  
pp. 43-48 ◽  
Author(s):  
M Ahlberg ◽  
C Elvander ◽  
S Johansson ◽  
S Cnattingius ◽  
O Stephansson

2014 ◽  
Vol 69 (6) ◽  
pp. 307-308
Author(s):  
Christopher R. H. White ◽  
Dorota A. Doherty ◽  
John P. Newnham ◽  
Craig E. Pennell

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