A review on current strategies and emerging treatments in management of silicosis: An ayurveda perspective

Silicosis is a possibly deadly, irreversible, fibrotic pneumonic sickness that may create resulting to the inward breath of a lot of silica dust over the long haul. As a rule, silicosis just creates resulting to significant word related presentations. The sickness has a long idleness period and may clinically present as an intense, quickened, or ongoing infection.In this audit the medicines that can lessen the aggravation and scarring in which are as nodular injuries in the upper projections of the lungs. The principle point of audit is to the likely home grown treatment for silicosis. This survey zeroed in on different medicines which incorporate natural plants, neutraceuticals, polyherbals, and herbominerals and furthermore cell based treatment for silicosis.From that review we presume that the natural treatment which is utilized in treatment of silicosis is potential treatments which incorporate huge quantities of home grown plants, polyherbals, neutraceuticals and herbominerals likewise incorporate the new treatment for silicosis is the cell based treatment.

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Emerging Treatments for Castrate-Resistant Prostate Cancer

Journal of Pharmacy Practice ◽

10.1177/0897190010397718 ◽

2011 ◽

Vol 24 (4) ◽

pp. 366-373

Author(s):

Michell B. Redding ◽

Minal Surati

Keyword(s):

Prostate Cancer ◽

Antitumor Agents ◽

Specific Antigen ◽

Abiraterone Acetate ◽

Cytotoxic Agents ◽

Emerging Treatments ◽

Castrate Resistant Prostate Cancer ◽

New Treatment ◽

Castrate Resistant ◽

Androgen Depletion

Castrate-resistant prostate cancer (CRPC) is a challenging aspect in the treatment of prostate cancer. Research has identified several pathways in the pathogenesis of CRPC. Several new agents targeting some of these pathways have shown promising data during clinical trials. In the area of androgen depletion, abiraterone acetate and MDV100 have been studied and have shown to decrease prostate-specific antigen (PSA) levels in phase I and II studies. Bevacizumab is a monoclonal antibody antiangiogenesis agent that targets vascular endothelial growth factor (VEGF) and has shown to decrease PSA levels in combination with other cytotoxic agents. Three agents, ixabepilone, patupilone, and sagopilone, in the class of epothilones (tubulin polymerizing antitumor agents), have shown moderate reductions in PSA levels and moderate adverse effects. The results of ongoing studies with these new treatment agents may offer viable alternatives to the traditional treatment of CRPC to decrease disease progression and improve overall survival.

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Clearance of Free Silica in Rat Lungs by Spraying with Chinese Herbal Kombucha

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2013/790792 ◽

2013 ◽

Vol 2013 ◽

pp. 1-9 ◽

Cited By ~ 3

Author(s):

Nai-fang Fu ◽

Chang-hui Luo ◽

Jun-cai Wu ◽

Yan-yan Zheng ◽

Yong-jin Gan ◽

...

Keyword(s):

Lavage Fluid ◽

Silica Content ◽

Silica Dust ◽

Chinese Herbal ◽

Free Silica ◽

Cell Counts ◽

Histopathological Lesions ◽

New Treatment ◽

Experimental Treatments ◽

Macrophage Viability

The effects of spraying with kombucha and Chinese herbal kombucha were compared with treatments with tetrandrine in a rat silicosis model. Silica dust (50 mg) was injected into the lungs of rats, which were then treated with one of the experimental treatments for a month. The rats were then killed and the effects of the treatments were evaluated by examining the extent and severity of the histopathological lesions in the animals’ lungs, measuring their organ coefficients and lung collagen contents, determining the dry and wet weights of their lungs, and measuring the free silica content of the dried lungs. In addition, lavage was performed on whole lungs taken from selected rats, and the numbers and types of cells in the lavage fluid were counted. The most effective treatment in terms of the ability to reduce lung collagen content and minimize the formation of pulmonary histopathological lesions was tetrandrine treatment, followed by Chinese herbal kombucha and non-Chinese herbal kombucha. However, the lavage fluid cell counts indicated that tetrandrine treatment had severe adverse effects on macrophage viability. This effect was much less pronounced for the kombucha and Chinese herbal kombucha treatments. Moreover, the free silica levels in the lungs of animals treated with Chinese herbal kombucha were significantly lower than those for any other silica-exposed group. These preliminary results indicate that spraying with Chinese herbal kombucha preparations can effectively promote the discharge of silica dust from lung tissues. Chinese herbal kombucha inhalation may thus be a useful new treatment for silicosis and other pneumoconiosis diseases.

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Emerging Treatments for Vitiligo Offer Hope

Skin & Allergy News ◽

10.1016/s0037-6337(09)70033-6 ◽

2009 ◽

Vol 40 (2) ◽

pp. 33

Author(s):

KERRI WACHTER

Keyword(s):

Emerging Treatments

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Management of thoracic aortic lesions - the future is endovascular

VASA ◽

10.1024/0301-1526/a000183 ◽

2012 ◽

Vol 41 (3) ◽

pp. 163-176 ◽

Cited By ~ 6

Author(s):

Weidenhagen ◽

Bombien ◽

Meimarakis ◽

Geisler ◽

A. Koeppel

Keyword(s):

Thoracic Aorta ◽

Clinical Decision Making ◽

Treatment Options ◽

Clinical Decision ◽

Clinical Results ◽

Treatment Modalities ◽

Traumatic Rupture ◽

Descending Thoracic Aorta ◽

New Treatment ◽

Aneurysm Dissection

Open surgical repair of lesions of the descending thoracic aorta, such as aneurysm, dissection and traumatic rupture, has been the state-of-the-art treatment for many decades. However, in specialized cardiovascular centers, thoracic endovascular aortic repair and hybrid aortic procedures have been implemented as novel treatment options. The current clinical results show that these procedures can be performed with low morbidity and mortality rates. However, due to a lack of randomized trials, the level of reliability of these new treatment modalities remains a matter of discussion. Clinical decision-making is generally based on the experience of the vascular center as well as on individual factors, such as life expectancy, comorbidity, aneurysm aetiology, aortic diameter and morphology. This article will review and discuss recent publications of open surgical, hybrid thoracic aortic (in case of aortic arch involvement) and endovascular repair in complex pathologies of the descending thoracic aorta.

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