scholarly journals Evaluation of C-reactive protein and magnesium level in migraine patients on pre and post prophylactic treatment

2022 ◽  
Vol 7 (4) ◽  
pp. 295-300
Author(s):  
Aliya khaleel ◽  
A Shyam Sunder ◽  
G Meghana
Keyword(s):  
Prophylactic Treatment ◽  
Serum Magnesium ◽  
Pain Scale ◽  
Cerebrovascular Diseases ◽  
Magnesium Level ◽  
Serum Magnesium Level ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Before And After

Migraine affects the day to day life of the sufferers with the symptoms of photophobia and phonophobia with pulsatile or non-pulsatile headache lasting from 1 to 4 hours. Prophylactic treatment or anti-migraine drugs were given to migraineurs to overcome the complications. C-reactive protein (CRP) and Magnesium level of symptomatic migraineurs, which act as biomarkers for the inflammatory cerebrovascular diseases before and after the treatment with Sodium Divalproex, Flunarizine and Propranolol. The evaluation of C-reactive protein and magnesium levels are noted along with symptoms when they first walk into the clinic. Treatment provided with Sodium Divalproex, Flunarizine and Propranolol for one month. After 1 month, the same tests are being performed. During the test at first instance, the values of pain scale were 31%, CRP value for negative were 20% and positive were 80% and pre-test of Serum magnesium level was 8.8% and at the second visit the pain scale reduced to 10.25%; CRP level was negative 25% and positive was 75%; Serum Magnesium was 9.35%. So, the significant values are being measured by the statistics, which we applied and found P=0.05. The patients who visited first didn’t come for the second visit. So, the results might vary and the patients who visited for the second time after one-month treatment, some got effective results while others remained ineffective. The reason for being ineffective is that they might have adapted to their current regimen.

scholarly journals PERBANDINGAN KADAR MAGNESIUM SERUM SEBELUM DAN SESUDAH AKTIVITAS FISIK INTENSITAS BERAT

2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Gladys R. Rompas ◽  
Stefana H. M. Kaligis ◽  
Murniati Tiho
Keyword(s):  
Random Sampling ◽  
Serum Magnesium ◽  
Simple Random Sampling ◽  
Magnesium Level ◽  
Male Students ◽  
Enzymatic Reactions ◽  
Serum Magnesium Level ◽  
Before And After ◽  
Post Test ◽  
Vigorous Intensity

Abstract: Magnesium is an important cation in catalyzing more than 300 enzymatic reactions in the human body. As a multifunction mineral, magnesium has some major implications in physical activity. This study aimed to compare the serum magnesium level before and after vigorous intensity exercise. This was an experimental study with pretest and post-test design. Sample was collected using simple random sampling method. Twenty one male students of Faculty of Medicine Sam Ratulangi University participated in this study. Samples were designated to play futsal for 2 x 20 minutes, with 10 minutes break and no substitution. The results showed that the mean serum magnesium level before vigorous intensity exercise was 2.2029 mg/dL and after exercise was 2.0067 mg/dL. Analysis using paired sample t-test showed significant result (p=0.000). Conclusion: There was a significant differencce between serum magnesium level before and after vigorous intensity exercise.Keywords: serum magnesium level, exercise, vigorous intensityAbstrak: Magnesium berperan penting dalam mengatalisis lebih dari 300 reaksi enzimatik di tubuh manusia. Magnesium merupakan mineral serbaguna yang memiliki beberapa implikasi besar berkaitan dengan aktivitas fisik. Pada saat suatu aktivitas fisik, dapat terjadi perubahan kadar mineral tubuh sesuai dengan intensitas dan durasi latihan. Penelitian ini bertujuan untuk mendapatkan perbandingan kadar magnesium serum sebelum dan sesudah aktivitas fisik intensitas berat. Penelitian ini menggunakan metode eksperimental dengan pendekatan pretest-posttest. Sampel diperoleh melalui cara simple random sampling. Sebanyak 21 orang mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi dipilih menjadi responden untuk diperiksa kadar magnesium serumnya. Sampel diinstruksikan untuk melakukan olahraga futsal dengan durasi 2 x 20 menit, waktu istirahat selama 10 menit tanpa pergantian pemain. Hasil pemeriksaan kadar magnesium menunjukkan rerata kadar magnesium serum sebelum aktivitas fisik 2,2029 mg/dL dan rerata sesudah aktivitas fisik 2,0067 mg/dL. Hasil uji t berpasangan, memperlihatkan nilai signifikansi sebesar 0,000. Simpulan: Terdapat perbedaan yang signifikan antara kadar magnesium serum sebelum dan sesudah aktivitas fisik intensitas berat.Kata kunci: kadar magnesium serum, aktivitas fisik, intensitas berat

Chronic Induction of C-Reactive Protein by Hemodialysis, but Not by Peritoneal Dialysis Therapy

1996 ◽  
Vol 16 (2) ◽  
pp. 158-162 ◽  
Author(s):  
Marion Haubitz ◽  
Reinhard Brunkhorst ◽  
Eike Wrenger ◽  
Peter Froese ◽  
Matthias Schulze ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Renal Insufficiency ◽  
Chronic Renal Insufficiency ◽  
Inflammatory Activity ◽  
C Reactive Protein ◽  
Dialysis Therapy ◽  
Dialysis Treatment ◽  
Reactive Protein ◽  
Before And After ◽  
Patient Groups

Objective Evaluation of the inflammatory activity in patients on chronic peritoneal dialysis (PD) and patients on chronic hemodialysis (HD) in comparison to patients with chronic renal insufficiency without dialysis treatment and healthy volunteers. Design Open, non randomized prospective study. Setting Nephrology Department, including HD and PD therapy in a university hospital. Patients Twenty -four patients on chronic PD, 21 patients on chronic HD therapy using a cuprophan dialyzer, 16 patients with chronic renal insufficiency without dialysis treatment, and 33 healthy volunteers; 8 additional patients before and after initiation of chronic HD therapy. All patients and controls were without infection or immunosuppressive therapy. Main Outcome Measures As a marker of the inflammatory activity in the different patient groups, C-reactive protein (CAP) was measured serially using a sensitive, enzyme-Iinked, immunosorbent assay in order to detect values below the detection limit of standard assays. Results All patient groups had CAP levels higher than the normal controls (p < 0.01). Patients on HD had CAP levels significantly higher than PD patients (p < 0.01) whose levels were comparable to patients without dialysis therapy. Accordingly, longitudinal measurements before and after initiation of chronic HD showed a significant increase in CAP levels after the beginning of HD treatment (p < 0.04). Conclusions The results suggest that induction of the inflammatory activity is lower during PD compared to HD, since stimulation by the dialyzer membrane, dialysate buffer, or bacterial fragments in the dialysate is avoided. This observation might indicate a possible lower risk of long-term complications in patients with PD.

Comparison of the Neutrophil/Lymphocyte Ratio and C-Reactive Protein Levels in Patients With Amputation for Diabetic Foot Ulcers

2017 ◽  
Vol 16 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Hasan Metineren ◽  
Turan Cihan Dülgeroğlu
Keyword(s):  
Diabetic Foot ◽  
Inflammatory Marker ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
C Reactive Protein ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Protein Levels ◽  
Reactive Protein ◽  
Before And After

This study compared the effectiveness of the neutrophil/lymphocyte ratio (NLR) versus C-reactive protein (CRP) for evaluating the prognosis and degree of inflammation in patients with amputation for a diabetic foot ulcer (DFU). This study enrolled 56 patients with amputations for DFU with gangrene and compared the CRP levels and NLR measured before and after surgery. Overall, 24 patients (42%) died within 2 weeks postoperatively. Mortality increased with a preoperative/postoperative CRP difference ≤1.5 ( P < .001) and age 73 years or older ( P < .001). The postoperative NLR was lower than the preoperative value but was not significant as a prognostic or inflammatory marker ( P = .945). An increasing serum CRP level is a significant predictor of mortality. CRP and old age are reliable prognostic factors in patients with DFU.

scholarly journals SERUM MAGNESIUM LEVEL

2010 ◽  
Vol 17 (02) ◽  
pp. 279-285
Author(s):  
SADIA ZAFAR ◽  
HINA AYESHA ◽  
ASGHAR BUTT ◽  
Bushra Abdul Malik
Keyword(s):  
Serum Albumin Level ◽  
Serum Magnesium ◽  
Simple Random Sampling ◽  
Albumin Level ◽  
Magnesium Level ◽  
Healthy Children ◽  
Persistent Diarrhea ◽  
Serum Magnesium Level ◽  
Cross Sectional ◽  
Study Setting

Objectives: To evaluate serum magnesium level in children with 3rd degree malnutrition and to compare these values with healthy children. Study Design: Cross sectional comparative study. Setting and Duration: Pediatric Department of Allied Hospital Faisalabad from Oct. 2003 to Nov. 2004. Subjects: Cases: 60 children of age six month to five year having weight < 60% of that for age. Control: 60 healthy children of age six month to five year having weight > 80% of that for age. Methods: Both cases & controls were selected from indoor & outdoor through simple random sampling. Detailed history & examination was done and S/Mg level were measured by atomic absorption spectrophotometer. Data was analyzed with the help of SPSS by applying T test and was presented by frequency tables. Results: The cases showed decreased S/Mg level (1.11+/- 0.24 mg/dl) as compared to controls (2.01+/- 0.78mg/dl).S/Mg levels were also decreased in cases with height < 80 % of that for age (0.98+/-0.5mg/dl) as compared to controls having height > 90 % of that for age. S/Mg levels were markedly low in cases who had low albumin level (0.98+/- 0.05 mg/dl) and those children who presented with persistent diarrhea (0.96+/-0.12mg/dl) Conclusion: S/Mg levels were decreased in children with PEM as compared to those with age and sex matched control. This decrease in S/Mglevels was marked in those cases who had decrease serum albumin level and persistent diarrhea.

scholarly journals Association between Serum Magnesium Level with Acute Coronary Syndrome (ACS) in Diabetes Mellitus (DM) Patients

2019 ◽  
Vol 2 (2) ◽  
pp. 96
Author(s):  
Ratih Wulansari ◽  
Soebagijo Adi Soelistijo ◽  
Achmad Lefi
Keyword(s):  
Diabetes Mellitus ◽  
Acute Coronary Syndrome ◽  
Plaque Rupture ◽  
Serum Magnesium ◽  
Demographic Data ◽  
Cardiovascular Complications ◽  
Magnesium Level ◽  
Serum Magnesium Level ◽  
Coronary Syndrome ◽  
Normally Distributed

Introduction: Until now, cardiovascular complications are still the highest cause of death and disability in DM patients. Hypomagnesemia in DM accelerate atherosclerosis and can cause instability and plaque rupture which can lead to acute coronary syndrome.Methods: Design of this study was observational analytic using a "case control" study involved 76 samples of DM patients, consisting of 38 samples with SKA (+) and 38 samples with SKA (-). Subjects of this study were all DM patients in the period July-December 2018 in the Emergency Room (ER) and Outpatient Installation of Endocrine at the RSUD Dr. Soetomo Surabaya, which fulfills the criteria for inclusion and exclusion. Demographic data and clinical characteristics are presented descriptively. If data is normally distributed then an unpaired t test is carried out and if the data is not normally, distributed with Mann Whitney test is performed. The statistical test was stated to be significant if p <0.05. The association between hypomagnesemia and the incidence of ACS a multivariate logistic regression test was performed, the risk number was in the form of odds ratios (OR). Results: This study involved 76 subjects with diabetes mellitus with SKA and non SKA 38 subjects. The mean serum magnesium level in the ACS group was lower than non ACS (1.9 mg / dL vs. 2.1 mg / dL), hypomagnesemia cut-off of <2.08 mg / dL. In this study hypomagnesemia as a risk factor for the incidence of ACS in DM patients with OR 2.8 (CI 1.1-7.6; p = 0.039).Conclusion: Magnesium levels in the ACS group were lower than the non ACS group. Hypomagnesemia Increase The Incidence of Acute Coronary Syndrome in Diabetes Mellitus Patients.

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