Rivea Hypocrateriformis (Desr.) Choisy: A Review of its Ethnomedicinal Uses, Phytochemistry and Biological Activities

Rivea hypocrateriformis (Desr.) Choisy is a robust woody climbing shrub of the genus Rivea which is found in India, Nepal, Sri Lanka, Pakistan, Bangladesh, Myanmar and Thailand. R. hypocrateriformis is a promising medicinal herb with enormous helpful and wellbeing advancing impacts. R. hypocrateriformis has been utilized as a customary medication for a long time to treat rheumatic pain, fever, urogenital problem, snake bite, cough, piles, malaria, and skin disease. Apart from the traditional uses its leaves and young shoots are cooked and eaten as a vegetable and for preparation of bread with millet flour. This review comprehensively summarizes the up-to-date information on the botanical characterization, distribution, traditional uses, phytochemistry, pharmacology and toxicity study of R. hypocrateriformis. Phytochemical investigation has been revealed that alkaloids, glycosides, coumarins, flavonoids, xanthones, stilbenes, and other organic compounds are contained in R. hypocrateriformis. Crude extracts and isolated compounds have exhibited numerous pharmacological activities such as anovulatory effect, antifertility activity, antiarthritic, antimicrobial, anticancer, antioxidant, hepatoprotective, antilithiatic, antimitotic. R. hypocrateriformis is a promising restorative spice with monstrous remedial and wellbeing advancing impacts. Along these lines, further investigations on the bioactive mixtures and systems of R. hypocrateriformis are justified. Extra clinical and toxicological examinations are expected to assess its wellbeing.

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The Phytochemistry of Cherokee Aromatic Medicinal Plants

Medicines ◽

10.3390/medicines5040121 ◽

2018 ◽

Vol 5 (4) ◽

pp. 121 ◽

Cited By ~ 1

Author(s):

William Setzer

Keyword(s):

Native Americans ◽

Medicinal Plants ◽

Biological Activities ◽

Herbal Medicines ◽

Black Cohosh ◽

Cimicifuga Racemosa ◽

Traditional Uses ◽

Aromatic And Medicinal Plants ◽

Phytochemical Investigation ◽

Phytochemical Constituents

Background: Native Americans have had a rich ethnobotanical heritage for treating diseases, ailments, and injuries. Cherokee traditional medicine has provided numerous aromatic and medicinal plants that not only were used by the Cherokee people, but were also adopted for use by European settlers in North America. Methods: The aim of this review was to examine the Cherokee ethnobotanical literature and the published phytochemical investigations on Cherokee medicinal plants and to correlate phytochemical constituents with traditional uses and biological activities. Results: Several Cherokee medicinal plants are still in use today as herbal medicines, including, for example, yarrow (Achillea millefolium), black cohosh (Cimicifuga racemosa), American ginseng (Panax quinquefolius), and blue skullcap (Scutellaria lateriflora). This review presents a summary of the traditional uses, phytochemical constituents, and biological activities of Cherokee aromatic and medicinal plants. Conclusions: The list is not complete, however, as there is still much work needed in phytochemical investigation and pharmacological evaluation of many traditional herbal medicines.

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PHYTOCHEMICAL, PHARMACOLOGICAL SCREENING AND IMPORTANCE OF MARSDENIA TENACISSIMA: A REVIEW

INDIAN DRUGS ◽

10.53879/id.58.04.11607 ◽

2021 ◽

Vol 58 (4) ◽

pp. 7-22

Author(s):

Mayur Porwal ◽

◽

Arvind Kumar ◽

Kamal K. Maheshwari ◽

Najam A. Khan ◽

...

Keyword(s):

Heart Disease ◽

Skin Disease ◽

Recent Literature ◽

Biological Activities ◽

Intermittent Fever ◽

Pharmacological Activities ◽

Phytochemical Constituents ◽

Pharmacological Screening ◽

Anti Hiv ◽

Marsdenia Tenacissima

In conventional methods of medication, Marsdenia tenacissima (family: Apocynaceae) is used in the treatment of scurvy, urinary diseases, arthritis, heart disease, skin disease, pruritus, vomiting and intermittent fever. Estimation of biological activities confirmed that M. tenacissima plant shows antipyretic, antioxidant, anticancer and anti-HIV activities. This assessment presents the phytochemical constituents, traditional importance and pharmacological activities accounted for the plant in recent literature and it will be supportive to explore incisive information about M. tenacissima for the researchers.

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Traditional Uses, Phytochemistry, and Pharmacology of Elegia Species: A Review

Scientia Pharmaceutica ◽

10.3390/scipharm90010004 ◽

2021 ◽

Vol 90 (1) ◽

pp. 4

Author(s):

Panagiotis Lymperis ◽

Ekaterina-Michaela Tomou ◽

Marco Nuno De Canha ◽

Namrita Lall ◽

Helen Skaltsa

Keyword(s):

Biological Activities ◽

Chemical Constituents ◽

Pharmacological Activities ◽

Traditional Uses ◽

Comprehensive Search ◽

Extensive Information ◽

The Subject ◽

Phytochemical Profile ◽

Ecological Dominance ◽

New Research

In South Africa, plants belonging to the Restionaceae family possess an ecological dominance. As a result, they have been the subject of numerous morphological, anatomical, and evolutionary studies. However, few studies have focused on their phytochemical profile and their potential pharmacological activities. The genus Elegia L. is the second largest of this family comprising 52 species, which are mainly used as materials for thatching. Limited studies on the chemical constituents of Elegia species and their importance as medicinal plants have been undertaken. This review provides constructive and extensive information about the botanical characterization, distribution, traditional uses, phytochemistry and pharmacology of the genus Elegia. A comprehensive search of previously published literature was performed for studies on this genus, using databases with different key search words. This survey documented 52 Elegia species summarizing their previous taxonomic classification. In addition, 14 species were found to be studied for their phytochemical profile, revealing 14 chemical compounds. Concerning their biological activities, only one species (E. tectorum (L.f.) Moline and H.P.Linder) is reported for its anti-wrinkle activity. Moreover, two species are locally used for thatching and as materials for brooms. The present review highlights the Elegia genus as an important source of bioactive phytochemicals with flavonol glycosides being the main metabolites and reveals the uncharted territory of this genus for new research studies.

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Phytochemical Compounds and Pharmacological Activities of Vitis vinifera L.: An Updated Review

Biointerface Research in Applied Chemistry ◽

10.33263/briac115.1382913849 ◽

2021 ◽

Vol 11 (6) ◽

pp. 13829-13849

Keyword(s):

Vitis Vinifera ◽

Wound Care ◽

Biological Activities ◽

Vitis Vinifera L ◽

Pharmacological Activities ◽

Scientific Databases ◽

Traditional Uses ◽

Western Asia ◽

Phytochemical Compounds ◽

Nutritional Constituents

Grapes (Vitis vinifera L.) are commonly known grape species that belong to the Vitis genus in the Vitaceae family and come from western Asia and southern Europe. This review consists of traditional uses, phytochemical compounds, nutritional constituents, pharmacological activities, genotoxicological studies, and toxicity studies of V. vinifera. The data were obtained from scientific databases and search engines such as PubMed, Elsevier, Springer, Frontiers, Google Scholar, Scopus, Science Direct, and MDPI. In some countries, grapes used for traditional uses, such as drug therapy for blood-forming, anemia, allergies, wound care, colds and flu, carminative, bronchitis, diarrhea, and anti-phlegm. The main phytochemical compounds in V. vinifera are phenolic compounds, aromatic acids, flavonoids, proanthocyanidins, and stilbenoids. Nutritional constituents can be found in grapevines, i.e., proteins, lipids, carbohydrates, minerals, and vitamins. Parts of the grapevines had a wide variety of biological activities, i.e., antioxidant, antiviral, antiplatelet, antifungal, anticataract, antiobesity, anticholinergic, anti-sunburn, anti-inflammatory, and wound-healing activities. The phytochemical compounds content in each part of the grapevines were different. Each pharmacological activity depends on the grapevine's phytochemical compounds, components used, and extraction type. However, more studies are needed regarding the genotoxicity and toxicity of V. vinifera.

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A REVIEW: THIAZINES DERIVATIVES TREATED AS POTENTIAL ANTIMICROBIAL AGENTS

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i1.115467 ◽

2016 ◽

Vol 10 (1) ◽

pp. 43 ◽

Cited By ~ 3

Author(s):

Praveen Kumar Sharma ◽

Reena Makkar

Keyword(s):

Natural Products ◽

Organic Compounds ◽

Heterocyclic Compounds ◽

Antimicrobial Agents ◽

Biological Activities ◽

Natural World ◽

Antimicrobial Activities ◽

Pharmacological Activities ◽

Strong Reflection ◽

Anti Inflammatory

ABSTRACTIn recent days, heterocycles and their derivatives have become strong reflection in medicinal research and pharmaceutical fields because of theirpractical pharmacological and biological activities. Organic compounds; mainly heterocyclic compounds are wealthy in natural world and containextra value because their structural subunits are established in many natural products such as enzymes, vitamins, antibiotics, acids, and hormones.Thiazine nucleuses found in compounds have variety of pharmacological activities such as antitumor, antimicrobial, antibacterial, antifungal, antiviral,and anti-inflammatory. This review spotlight on the substituted thiazines with possible antimicrobial activities that are at the present in development.Keywords: Antibacterial, Substituted thiazines, Antimicrobial agents.

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Synthetic Methods, Chemistry, and the Anticonvulsant Activity of Thiadiazoles

International Journal of Medicinal Chemistry ◽

10.1155/2013/348948 ◽

2013 ◽

Vol 2013 ◽

pp. 1-16 ◽

Cited By ~ 9

Author(s):

Bhawna Sharma ◽

Amita Verma ◽

Sunil Prajapati ◽

Upendra Kumar Sharma

Keyword(s):

Anticonvulsant Activity ◽

Biological Activities ◽

Synthetic Methods ◽

Biological Behavior ◽

Hydrogen Binding ◽

Pharmacological Activities ◽

Long Time ◽

Intensive Investigation ◽

New Compounds ◽

Donor System

The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4-thiadiazole constitutes an important class of compounds for new drug development. The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. The search for antiepileptic compounds with more selective activity and lower toxicity continues to be an active area of intensive investigation in medicinal chemistry. During the recent years, there has been intense investigation of different classes of thiadiazole compounds, many of which possess extensive pharmacological activities, namely, antimicrobial activity, anticonvulsant, antifungal antidiabetic, anti-inflammatory, antioxidant, and antituberculosis activities, and so forth. The resistance towards available drugs is rapidly becoming a major worldwide problem. The need to design new compounds to deal with this resistance has become one of the most important areas of research today. Thiadiazole is a versatile moiety that exhibits a wide variety of biological activities. Thiadiazole moiety acts as “hydrogen binding domain” and “two-electron donor system.” It also acts as a constrained pharmacophore. On the basis of the reported literature, we study here thiadiazole compounds and their synthetic methods chemistry and anticonvulsant activity.

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Traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium A. Rich (Cochlospermaceae): a review

Future Journal of Pharmaceutical Sciences ◽

10.1186/s43094-020-00168-1 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Mubarak Hussaini Ahmad ◽

Abubakar Ibrahim Jatau ◽

Garba M. Khalid ◽

Omar Yahya Alshargi

Keyword(s):

Liver Diseases ◽

Bioactive Molecules ◽

Pharmacological Activities ◽

Main Text ◽

Traditional Uses ◽

Comprehensive Information ◽

The Family ◽

Arjunolic Acid ◽

Ethnomedicinal Uses ◽

Different Parts

Abstract Background The plant Cochlospermum tinctorium A. Rich is a sub-shrub that belongs to the family Cochlospermaceae. The plant has been used in traditional medicine for the treatment of malaria, rickets, stomachache, diarrhea, gastric ulcer, parasitic infestations, liver diseases, fever, pain, inflammation, infectious diseases, epilepsy, snake bite, burns, orchitis, labour, menstrual problems, and many other diseases. This review summarizes the traditional uses, phytochemistry, and pharmacological activities of Cochlospermum tinctorium. Main text To date, few bioactive molecules have been identified and isolated from the plant such as 7,3-dimethyldihydroquercelin, 5,4-dimethylquercelin, cochloxanthine, dihydrocochloxanthine, arjunolic acid, 3-O-E-p-coumaroylalphitolic acid, alphitolic acid, 1-hydroxytetradecan-3-one, 3-bisabolen, 2-tridecanone, 3-hexadecanone, 1-dodecanol, l-tetradecanol, 2-pentdecanone, 3-octadecanone, 1-hydroxy-3-hexadecanone, 1-nonadecanol, l-O-acetyl-3-hexadecanone, and l-hydroxy-3-oetadecanone. The literature related some of the reported ethnomedicinal uses of the plant to these compounds found in the different parts of the plant. Conclusion The comprehensive information documented in this review about the importance of the C. tinctorium may provide an opportunity for research advancement in drug discovery and a better understanding of the medicinal benefits of the plant.

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A review on Lantana rhodesiensis Moldenke: traditional uses, phytochemical constituents and pharmacological activities

International Journal of Phytomedicine ◽

10.5138/09750185.1941 ◽

2017 ◽

Vol 9 (1) ◽

pp. 01 ◽

Cited By ~ 1

Author(s):

BANGOU Mindiédiba Jean ◽

MEDA Roland Nâg-Tiero ◽

KIENDREBEOGO Martin ◽

NACOULMA Odile Germaine ◽

ALMARAZ-ABARCA Norma

Keyword(s):

Diabetes Mellitus ◽

Chemical Composition ◽

Biological Activities ◽

Folk Medicine ◽

Literature Survey ◽

Parasitic Diseases ◽

Pharmacological Activities ◽

Traditional Uses ◽

Whole Plant ◽

Phytochemical Constituents

Lantana rhodesiensis Moldenke an herbaceous, belonging to the Verbenaceae family is widely used in Africa folk medicine for the treatment of cancer, measles, malaria, smallpox, strength, coughs, fever, rheumatism, body pains, diabetes mellitus arrhythmia, parasitic diseases, arterial hypertension, old diarrhoeas. Many studies have been conducted on the chemical composition of the whole plant of L. rhodesiensis as well as biological activities. The aim of the present review was to give a detailed literature survey on its traditional uses, phytochemistry and therapeutical properties of L. rhodesiensis.

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A perspective review of phytochemistry and pharmacology of the Syzygium genus

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v12i2.4722 ◽

2021 ◽

Vol 12 (2) ◽

pp. 1490-1495

Author(s):

Yuniarni U ◽

Sukandar E Y ◽

Fidrianny I

Keyword(s):

Traditional Medicine ◽

Pharmacological Activity ◽

Therapeutic Potential ◽

Biological Activities ◽

Ornamental Plants ◽

Chemical Compounds ◽

Chemical Components ◽

Pharmacological Activities ◽

Widespread Species ◽

Traditional Uses

Syzygium is a genus of the Myrtaceae family consisting of large and widespread species from Africa, Asia, Australia, and throughout Oceania and the Pacific region. Some have been cultivated for bearing fruit, ornamental plants and used as traditional medicine. This article excavated Syzygium genus which was focused on traditional uses, chemical compounds and biological activities related to treatment of syndrome metabolic. All information was obtained from the scientific literature such as Science Direct, Google Scholar, Scopus and PubMed. Several species were known to have therapeutic potential and used in traditional Chinese medicine, Ayurveda, and herbal medicine in Indonesia. Traditionally, Syzygium is known for its therapeutic purposes such as coughing, diarrhea, colds, dysentery, inflammation, pain, skin, and mouth infections. Only a few species have been scientifically studied to verify their usage as traditional medicine. There were many reports on the traditional uses and medicinal effects of Syzygium plants, but only a few review articles mainly about phytochemical constituents and their role in pharmacological activities. The present reviews highlight the phytochemical and pharmacological activity of various species of the Syzygium genus. The pharmacological activities were discussed in this article focused to metabolic syndrome treatment, such as antidiabetic, antihyperlipidemic, antioxidant and antihypertensive activities. Chemical components isolated mainly flavonoid, terpenoids/sesquiterpenoid, sterols, and lignan. Several bioactive compounds have been identified correlated with pharmacological activity, but the chemical compounds were different for each species.

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Secoiridoid Amarogentin from ‘Gentianaceae’ with their Health Promotion, Disease Prevention and Modern Analytical Aspects

Current Bioactive Compounds ◽

10.2174/1573407214666181023115355 ◽

2020 ◽

Vol 16 (3) ◽

pp. 191-200

Author(s):

Kanika Patel ◽

Dinesh K. Patel

Keyword(s):

Modern Medicine ◽

Anticancer Activities ◽

Pharmacological Activities ◽

Long Time ◽

Pharmaceutical Industries ◽

Analytical Tools ◽

Ethnomedicinal Uses ◽

Common Plant ◽

Secoiridoid Glycoside ◽

Modern Analytical

Background: Plant-based products and their derivatives have been widely used in the medicine, nutraceuticals, and the cosmetic and pharmaceutical field for a very long time. A large number of important drugs of modern medicine have also been derived from the plant's sources. Plant products specifically the pure phytochemical also known as ‘biomarkers’ have been used in the food and pharmaceutical industries. Biomarker compounds are pure phytochemical and they are mainly responsible for various pharmacological activities of plant material and examples of biomarker are Amarogentin, Vasicine, Hyoscyamine and Paclitaxel. Methods: Various literature databases were searched to collect important information about Amarogentin in this review. Ethnomedicinal uses, pharmacological activities, phytochemical aspects and modern analytical tools of amarogentin were presented and discussed. Further, all the collected information’s were categorized into different section as per the need of the manuscripts. Moreover, data were also presented in the graphical abstract, Figures and Table section too. Results: Swertia chirata (S. chirata) is a common plant of Gentianaecae family which is mainly known for their bitter taste. Gentiopicroside, amarogentin, swertiamarin, isovitexin and isogentisin are some important phytoconstituents of S. chirata. Decoction, infusion, pastes and juice of S. chirata are basically used in the medicine. Various Pharmacological activities such as hypoglycemic, antimicrobial, antimalarial, antihepatotoxic, anticarcinogenic, antioxidative and anti-inflammatory have been reported in the literature for S. chirata plant. Amarogentin, a bitter secoiridoid glycoside of S. chirata has been well known for antibacterial, anticholinergic anti-lieshmanial, chemopreventive, antihepatitis and anticancer activities. Conclusion: Information provided in the present paper regarding phytochemistry, pharmacological uses and analytical aspects including bioavailability will be beneficial to various disciplines of biological science. Development of plant tissue culture-based approaches is also needed for the proper conservation of S. chirayita plants in the future.

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