STUDY OF BACTERIAL PATHOGENS IN URINARY TRACT INFECTION AND THEIR ANTIBIOTIC RESISTANCE PROFILE

2017 ◽  
pp. 2552-2558
Author(s):  
Jyotsana Sawant
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Bacterial Pathogens ◽  
Resistance Profile ◽  
Antibiotic Resistance Profile

scholarly journals Bacterial pathogens and antibiotic resistance patterns in children with urinary tract infection admitted at tertiary hospital in Nepal

2016 ◽  
Vol 3 (2) ◽  
pp. 32-35 ◽  
Author(s):  
Ganesh Shah ◽  
Bhishma Pokhrel ◽  
Anish Kumar Shah ◽  
Puspa Bahadur Bista ◽  
Asmita Bhattarai
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Bacterial Pathogens ◽  
Bacterial Pathogen ◽  
Health Sciences ◽  
Klebsiella Species ◽  
Cross Sectional ◽  
E Coli

Introductions: Urinary tract infection (UTI) is a common bacterial infection affecting children. A prompt recognition and accurate antimicrobial management are vital to prevent kidney damage. This study aims to determine the bacterial pathogens and their patterns of antimicrobial resistance in children presenting with UTI.Methods: This was a cross sectional study done at Patan Hospital, Patan Academy of Health Sciences, from Nov 2012 to Oct 2016. There were 88 children between age group of 1 to 14 years with culture proven UTI. The bacterial pathogens and antibiotic resistance were analysed.Results: Three most common organisms isolated were E. Coli 60 (68%), Klebsiella species 15 (17%) and Proteus 7 (8%). The resistance of E. Coli to ampicillin, ofloxacin, cefotaxime, gentamicin and amikacin were 51 (85%), 49 (82%), 45 (75%), 17 (28%) and 2 (3%) respectively. The resistance to ampicillin was Klebsiella species 13 (87%), Proteus 6 (86%) and Enterococcus 3 (60%).Conclusions: The E. Coli was leading bacterial pathogen causing UTI in children, with ampicillin resistance occurring in more than half of these cases. Amikacin and gentamicin had lower antibiotic resistance and can be used for treatment of UTI in children.Journal of Patan Academy of Health Sciences. 2016 Dec;3(2):32-35

The Benefits and Harms of Antibiotic Prophylaxis for Urinary Tract Infection in Older Adults

2021 ◽  
Author(s):  
Bradley J Langford ◽  
Kevin A Brown ◽  
Christina Diong ◽  
Alex Marchand-Austin ◽  
Kwaku Adomako ◽  
...  
Keyword(s):  
Older Adults ◽  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Prophylaxis ◽  
Bloodstream Infection ◽  
Antibiotic Treatment ◽  
Positive Culture ◽  
Clostridioides Difficile

Abstract Background The role of antibiotics in preventing urinary tract infection (UTI) in older adults is unknown. We sought to quantify the benefits and risks of antibiotic prophylaxis among older adults. Methods We conducted a matched cohort study comparing older adults (≥66 years) receiving antibiotic prophylaxis, defined as antibiotic treatment for ≥30 days starting within 30 days of a positive culture, with patients with positive urine cultures who received antibiotic treatment but did not receive prophylaxis. We matched each prophylaxis recipient to 10 nonrecipients based on organism, number of positive cultures, and propensity score. Outcomes included (1) emergency department (ED) visit or hospitalization for UTI, sepsis, or bloodstream infection within 1 year; (2) acquisition of antibiotic resistance in urinary tract pathogens; and (3) antibiotic-related complications. Results Overall, 4.7% (151/3190) of UTI prophylaxis patients and 3.6% (n = 1092/30 542) of controls required an ED visit or hospitalization for UTI, sepsis, or bloodstream infection (hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.12–1.57). Acquisition of antibiotic resistance to any urinary antibiotic (HR, 1.31; 95% CI, 1.18–1.44) and to the specific prophylaxis agent (HR, 2.01; 95% CI, 1.80–2.24) was higher in patients receiving prophylaxis. While the overall risk of antibiotic-related complications was similar between groups (HR, 1.08; 95% CI, .94–1.22), the risk of Clostridioides  difficile and general medication adverse events was higher in prophylaxis recipients (HR [95% CI], 1.56 [1.05–2.23] and 1.62 [1.11–2.29], respectively). Conclusions Among older adults with UTI, the harms of long-term antibiotic prophylaxis may outweigh their benefits.

scholarly journals Nontypable Haemophilus influenzae Septicemia and Urinary Tract Infection Associated with Renal Stone Disease

2018 ◽  
Vol 12 (1) ◽  
pp. 243-247
Author(s):  
Marianne Stærk ◽  
Sara A. Tolouee ◽  
Jens J. Christensen
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Haemophilus Influenzae ◽  
Renal Stone ◽  
Stone Disease ◽  
Upper Respiratory Tract ◽  
Renal Stone Disease ◽  
Tract Infections

Introduction: Haemophilus influenzae commonly causes upper respiratory tract infections and has only rarely been reported etiology of urinary tract infections. Since the introduction of the Haemophilus influenzae b (Hib) vaccine, non-typable haemophilus species now cause the majority of invasive disease in Europe. Case Report: We report a case of an adult man with non-typable Haemophilus influenzae septicemia, urinary tract infection and bilateral renal stone disease. The patient presented with right sided flank pain and a CT scan showed bilateral renal stones and a right sided ureteral stone causing obstruction. Results and Discussion: Haemophilus influenzae was identified in blood and urine and despite a tendency of increasing antibiotic resistance among Haemophilus influenzae, our strain was susceptible to all antibiotics tested. Treatment consisted of 3 days of intravenous cefuroxime, insertion of a right sided JJ ureteric stent and 5 days of peroral ciprofloxacin after discharge. Physicians and microbiologists should be aware of Haemophilus influenzae as a possible urinary tract pathogen, especially when urinary tract abnormalities are present, and take the risk of antibiotic resistance into consideration at initial treatment.

scholarly journals The Prevalence of Bacterial Pathogens associated with Urinary Tract Infection (UTI) among Patients attending Kam Medical Consult Clinic, Uganda.

2021 ◽  
Author(s):  
◽  
Gerald Turyatunga
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Bacterial Pathogens ◽  
Clinical Signs ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Etiological Agents ◽  
Tract Infections

Background: A urinary tract infection (UTIs) is a common type of infection caused by bacteria that travel up the urethra to the bladder. Globally, it is reported that 150 million people are diagnosed with a UTI annually, costing the world economy over 6 million US dollars in treatment and work loss. Studies conducted in the in-patients pediatric ward of Muhimbili Hospital in Tanzania and Mulago National Referral Hospital in Uganda between five to ten years reported the prevalence of UTI to be 16.8% and 14.6% respectively. On average at Kam Medical Consult Clinic, patients who turn up in the laboratory are about 20%, and 50% of patients present with recurring UTIs clinically. Therefore,  there is a need to establish and investigate the prevalence of bacterial pathogens associated with UTI and multiple pathogens that are not known. Methodology: The cross-sectional study was carried out at Kam medical consult clinic (KMCC) located in Kafeero zone Mulago II Kawempe division. The study population was adults and children presenting with symptoms of urinary tract infection. 120 Midstream urine Samples were collected from patients presenting clinical signs of UTI. The diagnosis was done through macroscopy dry chemistry, microscopy, and culture. Results Among the sampled population, 33% of males had urinary tract infections while 67% of females had urinary tract infections.  88.5% were outpatients while 11.5 % were in-patients The overall prevalence of UTI among patients was 63.3% with children aged (1-10) having a prevalence of 5.8 %. Conclusion and recommendation: E.coli is an etiological agent causing UTIs in male and female patients presenting UTI at Kam Medical Consult Clinic. Other etiological agents included Klebsiella, Coliform, Enterococcus species, staphylococcus aureus, pseudomonas species, and candida species. There is a need to monitor the profile of etiological bacteria of UTI through culture and sensitivity regularly. 

scholarly journals Antibiotic Resistance in Children with Recurrent or Complicated Urinary Tract Infection

2009 ◽  
Vol 48 (173) ◽  
Author(s):  
Nidal S Younish ◽  
K Qual ◽  
T Al-Awaisheh ◽  
F Al-Awaisheh ◽  
D Al-Kayed
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Recurrent Urinary Tract Infection ◽  
Complicated Urinary Tract Infection ◽  
Resistance Pattern ◽  
Candida Spp ◽  
Recurrent Uti ◽  
Antibiotics Susceptibility

INTRODUCTION:Urinary tract infection is certainly one of the most common childhood infections. Emerging resistance to the antibiotics is not unusual. Current hospitalization for children with urinary tract infection is reserved for severe or complicated cases. The aim of the present study was to determine the antibiotic resistance pattern among children with recurrent or complicated urinary tract infection.METHODS:A retrospective study carried out at Prince Hashem hospital, Zarqa city, eastern Jordan and involved 336 episodes of culture proved urinary tract infection obtained from 121 patients with recurrent UTI, who used prophylactic antibiotics during the period from April 1, 2004 to December 31, 2006. The isolated microorganisms and there antibiotics susceptibility were studied.RESULTS:Seventy three patients (60.3%) were found to have some forms of urinary tract anomaly, significantly more prevalent among male children P<0.001. Vesicoureteral reflux being the most common (58.9%). Renal scars were significantly more prevalent among those with complicated rather than recurrent urinary tract infection (64.3% vs. 16.6%, P<0.001). Gram negative organisms were the most frequent isolates in patients with recurrent and complicated urinary tract infection. Proteus, Pseudomonas and Candida spp. were more prevalent in patients with complicated (P<0.001), and isolates in patients with UTA were significantly more resistant to most antibiotics tested.CONCLUSIONS:Pediatric urine culture isolates are becoming increasingly resistant to commonly used antibiotics. Empirical treatment with Trimethoprim-Sulfamethoxazole (TMP-SMX) or Cephalexin as the initial drug is ineffective. Nitrofurantoin and Nalidixic acid can be considered as the first line antibiotics for prophylaxis and or treatment of patients with recurrent UTI, while Meropenam and Ciprofloxacin can be used empirically in treating patients with complicated UTI.Key words: Antibiotic resistance, Complicated, Recurrent, Urinary tract infection

ANTIBACTERIAL ACTIVITY OF MEDICINAL PLANTS AGAINST MULTI DRUG RESISTANT URINARY TRACT INFECTION CAUSING ORGANISMS

2021 ◽  
Vol 1 (6) ◽  
pp. 85-95
Author(s):  
Perumal G
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Medicinal Plants ◽  
Tract Infection ◽  
Pathogenic Bacteria ◽  
Bacterial Pathogens ◽  
Drug Resistant ◽  
Antibiotic Drug ◽  
Phytochemical Studies

The present study was isolate Bacterial pathogens form Urinary Tract Infection and identified the Bacterial pathogens from UTI patients. Determination of the antibiotic drug resistant pattern of the isolated pathogenic bacteria using standard antibiotic discs Ampicilin (25μg), Erithromycin (15μg), Chloramphenicol (10μg) Gentamicin (10μg) and Tetracycline (30 μg).The study was carried out, in vitro screening of ethanolic extracts of some medicinal plants against the bacterial pathogens Escherichia coli, Proteus vulgaris, Staphylococcus aureus and Pseudomonas aeruginosawere isolate from the UTI. When compared with standard antibiotic disc selected plants extracts were showed maximum zone of inhibition against all the pathogens. This investigation strongly recommends that phytochemical studies are required to determine the types of compounds responsible for the antibacterial effect of these medicinal plants. Key words: Bacterial pathogens, Antibiotic drug resistant pattern and Medicinal plants

Urinary Tract Infection Caused By Bacterial Pathogens of The Respiratory Tract In Children

2022 ◽  
Author(s):  
Yoko Takahashi ◽  
Takanori Funaki ◽  
Akira Ishiguro ◽  
Isao Miyairi
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Disease Surveillance ◽  
Bacterial Pathogens ◽  
Tertiary Care ◽  
Laboratory Data ◽  
Urinary Tract Abnormalities ◽  
Vesicocutaneous Fistula

Abstract Urinary tract infection (UTI) caused by bacterial pathogens of the respiratory tract such as Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis is rare and little is known about their characteristics and potential host risk factors. We conducted a retrospective descriptive study on pediatric UTI due to S. pneumoniae, Haemophilus spp., or M. catarrhalis at a tertiary-care pediatric hospital. Pediatric patients with diagnosed UTI between 2002 and 2020 were included. Patient demographics, laboratory data, and microbiological findings were extracted from their electronic medical records and the infectious disease surveillance system. Among 46,332 urine samples, 76 bacteriuria (0.16%) and 22 UTI (0.05%) events due to the targeted species were identified (S. pneumoniae [n=7] and Haemophilus spp. [n=15]). Of the patients, 17 (85%) had underlying urinary tract abnormalities and 13 (60%) had vesicocutaneous fistula. All the UTI episodes caused by S. pneumoniae and Haemophilus spp. occurred after cystostomy. All the patients had satisfactory clinical outcomes.Conclusion: Although S. pneumoniae and Haemophilus spp. are rare causes of UTI in children, they could be the true causative bacteria of UTI even when detected in urine specimens, particularly in the patients with urinary tract abnormalities and vesicocutaneous fistula.

Sign in / Sign up

Export Citation Format

Share Document