scholarly journals The role of red blood cell distribution width (RDW) in cardiovascular risk assessment: useful or hype?

2019 ◽  
Vol 7 (20) ◽  
pp. 581-581 ◽  
Author(s):  
Cristiano Fava ◽  
Filippo Cattazzo ◽  
Zhi-De Hu ◽  
Giuseppe Lippi ◽  
Martina Montagnana
Keyword(s):  
Risk Assessment ◽  
Cardiovascular Risk ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Cardiovascular Risk Assessment ◽  
Distribution Width ◽  
Red Blood Cell Distribution

scholarly journals Prognostic Role of the Red Blood Cell Distribution Width (RDW) in Hodgkin Lymphoma

Cancers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3262
Author(s):  
Ines Herraez ◽  
Leyre Bento ◽  
Raquel Del Campo ◽  
Adriana Sas ◽  
Rafael Ramos ◽  
...  
Keyword(s):  
Blood Cell ◽  
Hodgkin Lymphoma ◽  
Red Blood Cell ◽  
Prognostic Scores ◽  
Cell Distribution ◽  
Secondary Malignancies ◽  
Prognostic Role ◽  
Distribution Width ◽  
Red Blood Cell Distribution

The red blood cell distribution width (RDW) is a parameter available from an automated blood count, which measures the degree of heterogeneity of erythrocyte volume and increases in inflammatory conditions. The prognostic role of RDW has been described in different types of cancers. Hodgkin lymphoma (HL) is a hematological malignancy, known to have a proinflammatory background. We aim to study the prognostic role of RDW in HL. We retrospectively analyzed 264 patients with HL from two hospitals in the Balearic Islands between 1990 and 2018. Higher levels of RDW were independently related to anemia, B-symptoms, and low albumin. In age ≥45 years, the presence of lymphopenia and higher RDW were independently associated with worse event-free survival (EFS) and overall survival (OS). Long-term incidence of secondary malignancies was significantly higher in patients with higher RDW, particularly lung cancer. In conclusion, we report for the first time that RDW is a simple, cheap, and easily available prognostic factor in HL that identifies a group with worse EFS, OS, and a higher potential incidence of secondary malignancies. RDW seems to be related to most adverse prognostic factors in HL, making RDW an excellent candidate to be included in prognostic scores for HL.

scholarly journals Prognostic role of pretreatment red blood cell distribution width in patients with cancer: A meta-analysis of 49 studies

2019 ◽  
Vol 10 (18) ◽  
pp. 4305-4317 ◽  
Author(s):  
Peng-Fei Wang ◽  
Si-Ying Song ◽  
Hang Guo ◽  
Ting-Jian Wang ◽  
Ning Liu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Meta Analysis ◽  
Cell Distribution ◽  
Prognostic Role ◽  
Distribution Width ◽  
Patients With Cancer ◽  
Red Blood Cell Distribution

scholarly journals Red blood cell distribution width and outcome in trauma patients

2021 ◽  
Vol 121 (2) ◽  
pp. 221-228
Author(s):  
McKenzie Brown ◽  
Sean Nassoiy ◽  
Timothy Plackett ◽  
Fred Luchette ◽  
Joseph Posluszny
Keyword(s):  
Blood Cell ◽  
Hospital Mortality ◽  
Red Blood Cell ◽  
Trauma Patients ◽  
Cell Distribution ◽  
Distribution Width ◽  
Discharge Disposition ◽  
Trauma Service ◽  
Red Blood Cell Distribution

Abstract Context Red blood cell distribution width (RDW) has been used to predict mortality during infection and inflammatory diseases. It also been purported to be predictive of mortality following traumatic injury. Objective To identify the role of RDW in predicting mortality in trauma patients. We also sought to identify the role of RDW in predicting the development of sepsis in trauma patients. Methods A retrospective observational study was performed of the medical records for all adult trauma patients admitted to Loyola University Medical Center from 2007 to 2014. Patients admitted for fewer than four days were excluded. Admission, peak, and change from admission to peak (Δ) RDW were recorded to determine the relationship with in-hospital mortality. Patient age, development of sepsis during the hospitalization, admission to the intensive care unit (ICU), and discharge disposition were also examined. Results A total of 9,845 patients were admitted to the trauma service between 2007 and 2014, and a total of 2,512 (25.5%) patients fit the inclusion criteria and had both admission and peak values available. One-hundred twenty (4.6%) died while in the hospital. RDW values for all patients were (mean [standard deviation, SD]): admission 14.09 (1.88), peak 15.09 (2.34), and Δ RDW 1.00 (1.44). Admission, peak, and Δ RDW were not significant predictors of mortality (all p>0.50; hazard ratio [HR], 1.01–1.03). However, trauma patients who eventually developed sepsis had significantly higher RDW values (admission RDW: 14.27 (2.02) sepsis vs. 13.98 (1.73) no sepsis, p<0.001; peak RDW: 15.95 (2.55) vs. 14.51 (1.97), p<0.001; Δ RDW: 1.68 (1.77) vs. 0.53 (0.91), p<0.001). Conclusion Admission, peak, and Δ RDW were not associated with in-hospital mortality in adult trauma patients with a length of stay (LOS) ≥four days. However, the development of sepsis in trauma patients is closely linked to increased RDW values and in-hospital mortality.

The Role of Red Blood Cell Distribution Width in Pulmonary Embolism

CHEST Journal ◽  
2017 ◽  
Vol 152 (4) ◽  
pp. A1030
Author(s):  
Devi Sampat ◽  
Eric Bondarsky ◽  
Jason Filopei ◽  
Madeline Ehrlich ◽  
David Steiger
Keyword(s):  
Pulmonary Embolism ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
Red Blood Cell Distribution
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