Relationships of First Trimester Body Mass Index and Weight Change with Persistent Organic Pollutants Concentrations in Canadian Pregnant Women

Abstract Background Persistent organic pollutants (POPs) are toxic chemicals with demonstrable effects on pregnancy and neonatal outcomes. The associations of early pregnancy body mass index (BMI) and antenatal weight changes with circulating POP concentrations are poorly understood in the Canadian context. The objective of this study is thus to examine the relationships between first trimester maternal BMI, weight change from pre-pregnancy to 6-13 weeks of pregnancy (early gestational weight change), and first trimester plasma POP concentrations among Canadian pregnant women. Methods We conducted a secondary analysis of data collected as part of the Maternal-Infant Research on Environmental Chemicals (MIREC) Study. We determined the POP concentrations across first trimester BMI category (underweight/normal weight, overweight, class I & II obese, and class III obese) and early gestational weight change categories (weight loss, weight neutral/gain) and tested for overall differences using Kruskal-Wallis tests. Associations between first trimester maternal BMI and early gestational weight changes with the plasma concentrations of 41 POPs measured in the first trimester were further evaluated using unadjusted and adjusted censored regression models. Results Eleven of 41 POPs were detectable in at least 50% of the MIREC participants and could be analyzed for their relationships with first trimester BMI and weight change. The majority of POPs were inversely associated with first trimester BMI after controlling for the main confounding variables. Although not statistically significant, POP plasma concentrations tended to be generally higher in participants who lost weight compared to those who gained weight or whose weight stayed relatively stable from pre-pregnancy into the first trimester. Conclusions Our findings lend support to the hypothesis that pregnant women with obesity may have higher bioaccumulation of POPs within their adipose tissues than normal weight pregnant women. Additionally, early gestational weight loss appears to be associated with the highest circulating POP levels. Future studies should focus on the effect of weight changes on POPs concentrations across trimesters.

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Risk Factors Related to Weight Gain for Chines During Home Confinement in COVID-19 Pandemic: An Observational Retrospective Study

10.21203/rs.3.rs-55697/v1 ◽

2020 ◽

Author(s):

Qing-Song Xia ◽

Fan Wu ◽

Ming-Ming Gong ◽

Yan Zhao ◽

Ding-Kun Wang ◽

...

Keyword(s):

Risk Factors ◽

Weight Loss ◽

Weight Gain ◽

Food Intake ◽

Linear Regression ◽

Observational Study ◽

Weight Change ◽

Normal Weight ◽

Weight Changes ◽

Daily Exercise

Abstract Objective: The observational study was intended to explore the weight changes and risk factors of weight gain during the self-quarantine and find available methods to lose weight.Method: This was an online retrospective observational study investigating the weight changes before and after home confinement. A total of 530 participants completed the online questionnaire. diet, sleep, self-reported depression, disease history and exercise information possibly relating to weight changes were incorporated into the questionnaire. The differences among four groups (underweight, normal weight, overweight and obesity) in BMI change and weight change were compared, and the risk factors of weight gain was also analyzed by multiple linear regression analysis. Result: Participants were mostly between 21-50 years old, getting an average weight change of 0.82±3.31kg, and an average BMI change of 0.35 [-0.37, 1.00]. 43.77% of them gained weight by 2.99±2.29kg averagely. People with normal weight were easier to gain weight than obese group (p=0.001). There were differences in food intake (p<0.001), eating habits(p<0.001), taste preference (p=0.047), daily exercise step change(p=0.007), exercise (p=0.02) between non-weight gain group and weight gain group. The multiple linear regression revealed that weight gains were associated with sex (p=0.002), food intake (p=0.004), current daily exercise step (p=0.009) and self-reported depression (p=0.002) and weight loss was related to food intake (p=0.004) and pre-BMI (p=0.001).Conclusion: Eating irregularly, increasing food intake, self-reported depression and decreased daily steps were risk factors of weight gain, yet weight loss was related to decreased food intake and pre-BMI.

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Radioimmunoassay of plasma ouabain in healthy and pregnant individuals

Journal of Endocrinology ◽

10.1677/joe.0.1650669 ◽

2000 ◽

Vol 165 (3) ◽

pp. 669-677 ◽

Cited By ~ 28

Author(s):

O Vakkuri ◽

SS Arnason ◽

A Pouta ◽

O Vuolteenaho ◽

J Leppaluoto

Keyword(s):

Pregnant Women ◽

Human Plasma ◽

High Performance ◽

Chemical Nature ◽

Solid Phase ◽

Plasma Concentrations ◽

First Trimester ◽

Plasma Samples ◽

Third Trimester ◽

Endogenous Substances

Ouabain was recently isolated from human plasma, bovine hypothalamus and bovine adrenal in attempts to identify endogenous substances inhibiting the cell membrane sodium pump. A number of radioimmunoassays have been developed in order to study the clinical significance of ouabain. The results have been controversial with regard to the presence and chemical nature of plasma ouabain-like immunoreactivity. We have now measured ouabain in healthy and pregnant individuals using solid-phase extraction of plasma samples followed by a new radioimmunoassay with the extraordinary sensitivity of at least 2 fmol/tube (5 pmol/l). Plasma extracts, a previously isolated human plasma ouabain-like compound and bovine hypothalamic inhibitory factor displaced the tracer in parallel and eluted identically with ouabain in high-performance liquid chromatography. Plasma ouabain immunoreactivity was found to be much lower than reported previously: 12.6+/-1.3 pmol/l in healthy men (mean+/-s.e., n=20) and 9.4+/-0.7 pmol/l in women (n=14). In pregnant women (n=28) plasma ouabain concentration was 16.3+/-4.0 pmol/l during the first trimester, 18.8+/-4.3 pmol/l during the second trimester and 24.3+/-4.0 pmol/l during the third trimester (all P<0.01 compared with non-pregnant women). Plasma ouabain 3-5 days after the delivery was 13.6+/-1.1 pmol/l (n=10, P<0.05-0.01 compared with second and third trimesters). The pregnancy-related changes in the plasma concentrations of ouabain resembled those of cortisol. Therefore cortisol was measured from the same plasma samples and a significant positive correlation was found (r=0.512, P=0.006). The similar profiles of plasma ouabain and cortisol during pregnancy and their rapid decreases postpartum are consistent with the adrenal cortical origin of ouabain and also show that the secretions of these hormones are possibly under the control of same factors.

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The role of the platelet profile in the prediction of gestational diabetes

10.51271/kmj-0012 ◽

2021 ◽

pp. 50-54

Keyword(s):

Body Mass Index ◽

Blood Glucose ◽

Gestational Diabetes ◽

Pregnant Women ◽

Body Mass ◽

First Trimester ◽

Oral Glucose ◽

Mean Corpuscular Hemoglobin ◽

Lymphocyte Ratio ◽

Significant Difference

Objective: In our study, the results of oral glucose tolerance test (OGTT) and other hemogram parameters of pregnant women with and without gestational diabetes mellitus (GDM) were compared. The aim of our study is to investigate the benefit of these parameters in predicting GDM risk. Material and Method: The study was planned as a descriptive, retrospective and cross-sectional study. It was included 218 pregnant women who applied to the Gynecology and Obstetrics Clinic of Amasya Sabuncuoğlu Şerefeddin Training and Research Hospital between January 01, 2019 and January 31, 2020. It was examined complete blood count parameters, ultrasound findings, complete urinalysis, first trimester blood glucose, body mass index, age, and gravide parameters the patients we included in the study. The results were analyzed retrospectively and was evaluated the statistical significance relationship with gestational diabetes. Results: There was no statistically significant difference in age, body mass index (BMI), obesity status and number of gravida between the pregnant women who were examined and those without GDM (p> 0.05). The hemoglobin, platelet count, mean platelet volume (MPV), mean corpuscular volume (MCV), mean corpuscular hemoglobine (MCH), and mean corpuscular hemoglobin concentration (MCHC) values, and neutrophil, lymphocyte, monocyte and basophil counts, urine density and femur length were statistically significant. There was no difference (p> 0.05). No statistically significant difference was found in terms of neutrophile lymphocyte ratio (NLR), neutrophile monocyte ratio (NMR), platelet lymphocyte ratio (PLR), monocyte eosinophil ratio (MER), platelet MPV ratio (PMPVR), and platelet neutrophile ratio (PNR) values (p> 0.05) Conclusion: HbA1c, hematocrit and blood glucose in the first trimester may be predictors of GDM. In addition, we think that further studies are needed in a prospective design in more patients in terms of others parameters.

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The influence of pre-pregnancy body mass index and gestational weight gain on pregnancy outcomes in two-child women

10.21203/rs.2.16978/v1 ◽

2019 ◽

Author(s):

Hanqing Chen ◽

Suhua Zou ◽

Zhuyu Li ◽

Jianbo Yang ◽

Jian Cai ◽

...

Keyword(s):

Body Mass Index ◽

Weight Gain ◽

Gestational Weight Gain ◽

Body Mass ◽

Perinatal Outcomes ◽

Normal Weight ◽

Excessive Weight Gain ◽

Gestational Weight ◽

Excessive Weight ◽

Weight Gain During Pregnancy

Abstract Background Pre-pregnancy body mass index and gestational weight gain were related to perinatal outcomes. It was not know the changes of pre-pregnancy body mass index, weight gain during pregnancy and its effect on perinatal outcomes in two-child women.Methods This was a retrospective study. Data of single term women delivered in the First Affiliated Hospital of Sun Yat-sen University were collected from July 2017 to June 2018. Gestational weight gain criteria of the American Institute of Medical Research and pre-pregnancy body mass index classes were used to evaluate the effects on pregnancy outcomes.Results A total of 3049 cases were enrolled in the study. Overweight cases was 9.0% and obesity was 2.4%. The weight gain of the two-child women was less than that of primipara(12.4±3.9vs13.3±4.0kg, P<0.001). The proportion of primipara with excessive weight gain was higher compared to two-child women(20.1%versus17.3%, P<0.001). There were 40.0% overweight primipara and 55.2% of two-child women had excessive weight gain. And 40.5% primipara and 54.5% two-child women of obesity had excessive weight gain during pregnancy. Obese primipara increased the risk of pre-eclampsia (aOR2.38, 95%CI 0.76-7.46). And the odds of diabetes mellitus and large for gestational age also increased in this group (aOR3.49, 95%CI 1.46-8.35 and aOR7.65, 95%CI 1.83-31.97, respectively). Two-child women had similar results. Underweight primipara with excessive weight gain increased the pre-eclampsia risk (aOR2.26, 95%CI 0.29-17.46). Normal weight and overweight/obese primipara also had similar results. But in two-child women, only overweight/obesity increased the risk of pre-eclampsia (aOR2.01, 95%CI 0.41-9.98). Underweight two-child women with less weight gain increased the risk of diabetes(aOR2.06, 95%CI 0.43-9.8). Two-child women with overweight/obese increased the odds of LGA even if they had less weight gain(aOR2.58, 95%CI 0.11-63.22). Normal weight primipara and two-child women with overweight and obese with excessive weight gain had similar results. On the other way, underweight primipara with less weight gain increased the risk of SGA(aOR1.74, 95%CI 0.81-3.76).Conclusions Gestational weight gain of two-child women was less than primipara. Overweight/obese women with excessive weight gain of two-child women increased the risk of adverse outcomes.

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FIRST TRIMESTER MATERNAL BMI AND PREGNANCY OUTCOME AT DMCH, LAHERIASARAI, BIHAR

10.36106/ijsr/6930378 ◽

2020 ◽

pp. 79-81

Author(s):

Supriya Kumari ◽

Surya Narayan ◽

Kumudini Jha ◽

Debarshi Jana

Keyword(s):

Pregnancy Outcome ◽

Pregnancy Outcomes ◽

First Trimester ◽

Normal Weight ◽

Obese Women ◽

Family History Of Diabetes ◽

Medical College ◽

Asian Indian Women ◽

Adverse Pregnancy ◽

Maternal Bmi

Aim: The aim of the study was to find out relationship of maternal BMI to pregnancy outcome. Methodology: The study carried out in Department of Obstetrics and Gynaecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar from February 2019 to January 2020 and pregnancy outcomes were analyzed in relation BMI recorded in first trimester of primigravida. Results: Mean age of pregnant women was 26.2 years. At first booking obese women were significantlyolder (28.0 years) than others. Family history of diabetes was significantly higher among obese women (8.25%) compared to others. Rates of cesarean sections were higher in obese compared to others. The macrosomia rates were higher in obese compared to other group. The preeclampsia (1.89%), were significantly higher in obese women than others. Conclusions: Obese women were at a high risk of developing adverse pregnancy outcomes in terms ofgestational diabetes, macrosomia, preeclampsia more of ceasarean section. Normal weight women have low risk for cesarean section and macrosomia. These results highlight the need for preconception counseling, especially for obese and overweight and have beneficial outcomes in Asian Indian women.

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The possibility of modifications methods of determine volume of amniotic fluid

Journal of obstetrics and women s diseases ◽

10.17816/jowd65312-17 ◽

2016 ◽

Vol 65 (3) ◽

pp. 12-17

Author(s):

Viktor A Mudrov

Keyword(s):

Body Mass Index ◽

Amniotic Fluid ◽

Pregnant Women ◽

Body Mass ◽

Gestational Age ◽

First Trimester ◽

Fetal Weight ◽

Abdominal Circumference ◽

Pregnancy And Childbirth ◽

Maternity Hospitals

Selection of the optimal tactics of pregnancy and childbirth significantly depends on the expected volume of amniotic fluid. The amount of amniotic fluid reflects a condition of a fetus and changes at pathological conditions of both a fetus, and an uteroplacental complex. The aim of the study was a modification of methods for determining the expected volume of amniotic fluid. On the basis of maternity hospitals Trans-Baikal Region in the years 2013-2015 was held retrospective and prospective analysis of 300 labor histories, which were divided into 3 equal groups: 1 group - pregnant women with a body mass index (BMI) for Quetelet less than 24, Group 2 - with a BMI from 24 to 30, group 3 - with a BMI more than 30. In order to determine the expected volume of amniotic fluid were used the subjective method, the Chamberlain’s and Phelan’s methods. The error in determining volume of amniotic fluid by the existing methods exceeds 10 %, that defined need of creation of a quantitative method. On the basis of mathematical and 3d-modeling of the volume of amniotic fluid and fetal weight determined pattern change, which is expressed by the formula: VAF = IAF × М × π / GA2, where IAF - index of amniotic fluid (mm), M - fetal weight (g), GA - gestational age (weeks). Through a comprehensive analysis of anthropometric research of the pregnant women defined formula’s volume of amniotic fluid: V = 0,017 × HUF × (AC - 25 × BMI / GA)2 - М, where GA - gestational age (weeks), AC - abdominal circumference of the pregnant women (cm), BMI - body mass index for Quetelet in the first trimester of pregnancy (kg/m2), HUF - height of an uterine fundus (cm), M - the estimated fetal weight (g). In calculating volume of amniotic fluid according to the proposed ultrasonic formula error does not exceed 5,3 %, anthropometric formula error does not exceed 10,2 %. Thus, the method has a smaller error compared to the standard, and can be used to reliably determine volume of amniotic fluid in II and III trimester of pregnancy.

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Body Mass Index and Body Weight Perception among a Population of Female Adolescents

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2020.3865 ◽

2020 ◽

Vol 8 (E) ◽

pp. 308-312

Author(s):

Siham Lghoul ◽

Mohamed Loukid ◽

Mohamed Kamal Hilali

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Body Mass ◽

Weight Perception ◽

Normal Weight ◽

Female Adolescents ◽

Weight Changes ◽

Cross Sectional ◽

Body Weight Perception ◽

Physical Changes

BACKGROUND: Adolescence is associated with many physical changes, it is described as a period when body weight changes and is likely to become worrying for many adolescents. AIM: This study aims to evaluate associations between body weight perception and body mass index (BMI) among a population of female adolescents. METHODS: A cross-sectional school-based study was conducted from February to May 2017 among 12–19 years olds adolescents (n = 415) from high and middle school. BMI for age percentiles was calculated using the WHO AnthroPlus. Body weight perception was determined using an anonymous questionnaire. RESULTS: The prevalence of misconception of body weight was 60%. The prevalence of misconception was positively associated with the participants age (p < 0.001), the occurrence of menarche (p < 0.05), the increasing of BMI (p < 0.001), and with habits diet satisfaction (p < 0.05). Overweighed participants and who’s with normal weight were more likely to perceive their weight incorrectly (p < 0.05). Furthermore, approximately 2.9% of participants underestimated their true body weight and 57.1% overestimated their weight. However, all participants with underweight had correctly perceived their body weight. Logistic regression showed that predictor factors of misconception weight were participant’s age and BMI. CONCLUSION: It is recommended to improve healthy programs in schools aimed at preventing body weight perception and eating problems among adolescents.

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P–519 Investigation of embryo chromosomal constitution and live birth rate after vitrified-warmed euploid single blastocyst transfer across ranges of maternal body-mass-index

Human Reproduction ◽

10.1093/humrep/deab130.518 ◽

2021 ◽

Vol 36 (Supplement_1) ◽

Author(s):

G Fabozzi ◽

D Cimadomo ◽

M Allori ◽

A Vaiarelli ◽

S Colamaria ◽

...

Keyword(s):

Body Mass Index ◽

Maternal Age ◽

Perinatal Outcomes ◽

Normal Weight ◽

Maternal Body Mass Index ◽

Overweight Women ◽

The Mean ◽

Secondary Outcomes ◽

Maternal Bmi ◽

Euploidy Rate

Abstract Study question Does maternal body-mass-index (BMI) associate with blastocysts’ chromosomal constitution and clinical outcomes in infertile patients undergoing preimplantation genetic testing for aneuploidies (PGT-A)? Summary answer A higher euploidy rate per biopsied blastocyst was reported among underweight women. Overweight women were instead subject to higher miscarriage (MR) and lower live-birth-rates (LBR). What is known already Different studies in the literature revealed an association between BMI and infertility, suggesting a J-shaped relationship: both underweight and overweight women can suffer from infertility issues. Even if IVF might increase the success rate in both these categories of patients, it seems insufficient per se to overcome the complex and multifactorial fertility impairment derived from unbalanced nutritional intakes. Miscarriage, in particular, is common in both underweight and overweight women. However, most of the literature is based on chromosomally-untested embryos. Study design, size, duration: Retrospective observational study. Only the first IVF cycle with ≥1 biopsied blastocyst from each woman was included. The primary outcome was the association between maternal BMI (underweight, BMI<18.5, n = 160; normal-weight, BMI=18–25, N = 1392; overweight, BMI>25, N = 259) and the mean euploidy rate per cohort of biopsied blastocysts (m-ER). The secondary outcomes were the association between maternal BMI with clinical (mainly MR and LBR), gestational and perinatal outcomes after first vitrified-warmed single euploid blastocyst transfers. Participants/materials, setting, methods We included 1811 women undergoing PGT-A at a private IVF center between April–2013 and March–2020. The secondary outcomes were investigated on 1125 first vitrified-warmed single euploid blastocyst transfers from all patients obtaining ≥1 transferable blastocyst. Only ICSI with ejaculated sperm and continuous culture in standard incubators were performed. Logistic regressions were conducted to identify putative confounders and adjust the results accordingly. Main results and the role of chance Except for a lower maternal age among underweight women (38.3±3.1 versus 38.9±3.4 yr, p < 0.01) and higher among overweight ones (39.3±3.6 yr, p = 0.04), no difference was reported with respect to normal-weight women in terms of duration of infertility, hormonal levels, main cause of infertility, sperm quality, and reproductive history. The mean number of biopsied blastocysts was ∼3 in all groups. The m-ER shows a decreasing trend as the maternal BMI increases between 17 and 22–23, to then plateau. In fact, a significant difference was reported between underweight (50.8%±36.4%) and normal-weight women (41.4%±37.5%, p < 0.01). A linear regression adjusted for maternal age confirmed this moderate association between increasing BMI and m-ER (unstandardized-coefficient-B –0.6%, 95%CI:–1.1% to –0.1%, p = 0.02). Morphological quality and day of full-blastulation among transferred euploid blastocysts was similar in the three groups. Overweight women showed higher MR per pregnancy (N = 20/75, 26.7%, 95%CI:17.4%–38.3% versus N = 67/461, 14.5%, 95%CI:11.5%–18.2%; OR 2.0, 95%CI:1.1–3.6, p = 0.01) and lower LBR per transfer (N = 55/154, 35.7%, 95%CI:28.3%–43.8% versus N = 388/859, 45.2%, 95%CI:41.8%–48.6%; OR adjusted for euploid blastocysts’ features 0.67, 95%CI:0.46–0.96, p = 0.03). Clinical outcomes were instead similar among underweight and normal-weight women. All gestational and perinatal outcomes were comparable in the tree groups. Limitations, reasons for caution Our study is limited by its retrospective nature, and the fact that maternal BMI was measured only before oocyte retrieval and not before embryo transfer. Moreover, the reduced sample size did not allow for further relevant sub-analyses among solely obese women. Wider implications of the findings: When possible nutritional/lifestyle modifications should be encouraged to adjust maternal BMI before IVF. Overweight patients should be especially informed of their higher risk for miscarriage. Yet, BMI is just a gross marker, future studies based on body fat localization and percentage (e.g. by bioelectrical impedance analyses) are desirable. Trial registration number None

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Exploratory Study of the Relationship Between Maternal Body Mass Index and Spontaneous Fetal Movements

Inquiry@Queen's Undergraduate Research Conference Proceedings ◽

10.24908/iqurcp.8769 ◽

2016 ◽

Author(s):

Wei Ning (Will) Jiang

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Interrater Reliability ◽

Well Being ◽

Normal Weight ◽

Maternal Body Mass Index ◽

Body Movements ◽

Maternal Body ◽

Fetal Movements ◽

Maternal Bmi

Maternal body mass index (BMI) has been reported to be associated with the number of fetal body movements and the duration of fetal breathing movements in hypertensive pregnant women (Brown et al., 2008). However, whether a relationship exists in pregnancies classified as overweight or normal weight but not complicated by hypertension is unknown and the focus of this study. Forty-five maternal-fetal pairs (normotensive, normal weight=15; normotensive, overweight=15; hypertensive=15) who had participated in a study of fetal behavior which included a 20 min real-time ultrasound scan observation of fetal movements were randomly selected from the laboratory archival database. Gestational age at testing ranged from 33-39 weeks [M(SD)= 36.2 (1.4) weeks]. All infants were delivered healthy at term. Video-recordings of the ultrasound scans were scored for the number of fetal body movements (interrater reliability r=.97) and the cumulative duration of breathing (interrater reliability r=.94) movements. The number of fetal body movements differed between groups, F(2,38)=3.19, p=0.05, with fetuses of overweight mothers moving less frequently than those of normal weight mothers (M=9.7 vs 15.5, respectively). Maternal BMI prior to pregnancy, r=-0.43, p<0.01, and at time of observation, r=-0.44, p<0.01, was associated with the number of fetal body movements, but not with duration of breathing movements. As BMI increased, the number of fetal body movements decreased. It was concluded that maternal BMI may affect the number of spontaneous fetal movements. A prospective study is necessary to determine whether BMI should be considered when using body movement counts to assess well-being and/or neurodevelopment.

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Measured weight in early pregnancy is a valid method for estimating pre-pregnancy weight

Journal of Developmental Origins of Health and Disease ◽

10.1017/s2040174420000926 ◽

2020 ◽

pp. 1-9

Author(s):

Hazel Inskip ◽

Sarah Crozier ◽

Janis Baird ◽

Julia Hammond ◽

Sian Robinson ◽

...

Keyword(s):

Body Mass Index ◽

Weight Gain ◽

Standard Deviation ◽

Early Pregnancy ◽

First Trimester ◽

Limits Of Agreement ◽

Gestational Weight ◽

Measured Weight ◽

Pregnancy Weight ◽

Precise Assessment

Abstract Estimation of pre-pregnancy weight is difficult because measurements taken before pregnancy are rarely available. No studies have compared various ‘proxy’ measures using recalled weight or based on early pregnancy weight with actual measurements of pre-pregnancy weight. The Southampton Women’s Survey recruited women during 1998–2002 who were not pregnant. Data on 198 women with an estimated date of conception within 3 months of recruitment were analysed. Three proxy measures were considered: (1) recalled pre-pregnancy weight obtained during early pregnancy, (2) measured weight in early pregnancy and (3) estimated pre-pregnancy weight using a published model. Mean (standard deviation) recalled weight was 1.65 (3.03) kg lighter than measured pre-pregnancy weight, while early pregnancy weight and weights from the published model were 0.88 (2.34) and 0.88 (2.33) kg heavier, respectively. The Bland–Altman limits of agreement for recalled weight were −7.59 to 4.29 kg, wider than those for the early pregnancy weight: −3.71 to 5.47 kg and the published model: −3.68 to 5.45 kg. For estimating pre-pregnancy weight, we recommend subtraction of 0.88 kg from early pregnancy weight or the published model, or addition of 1.65 kg to recalled weight. Estimates of pre-pregnancy body mass index and gestational weight gain categories were very similar when using early pregnancy and published model weights, but they differed from those using recalled weight. Our findings indicate that calculations of first trimester weight gain using recalled weight must be treated cautiously, and a measured weight in early pregnancy provides a more precise assessment of pre-pregnancy weight than recalled weight.

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