scholarly journals Analysis of the Influence of Lifestyle on Liver Dysfunction Based on NAHANES Database

2021 ◽  
Author(s):  
Yan XU ◽  
Rong LIU
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Data Analysis ◽  
Liver Dysfunction ◽  
Positive Attitude ◽  
Sedentary Time ◽  
Survey Design ◽  
Sedentary Activity ◽  
Health And Nutrition ◽  
Inflection Points

Abstract ObjectiveTo find out the influence of various factors in life style on liver dysfunction, put forward reasonable suggestions on prevention of liver dysfunction.MethodsDatasets from 2017 to March 2020 NHANES (National Health and Nutrition Examination Surveys) required for the analysis were downloaded from the NHANES web site and R 4.1.1. Software was used for data analysis. Survey Design Logisitic regression was used to analyze the influence of various factors on liver dysfunction and screen the risk factors.Resultshypertension, depression, and sedentary activity are risk factors for liver dysfunction, while reducing salt in diet and vigorous recreational activities were protective factors for liver dysfunction. The inflection points of blood pressure, BMI and sedentary activity were 98.33mmHg, 30.6kg/m2, 420min, respectively.ConclusionsBlood pressure, BMI, mood and sedentary behavior are risk factors for liver dysfunction. We suggest that keeping MAP level at 70-98.33mmHg, controlling BMI < 30kg/m2, maintaining a positive attitude, and sedentary time less than 420 min per day are more conducive to reducing the risk of liver dysfunction.

scholarly journals Association between Parent’s Metabolic Syndrome and 12- to18-Year-Old Offspring’s Overweight: Results from the Korea National Health and Nutrition Examination Survey (K-NHANES) 2009–2016

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Na Yeong Lee ◽  
Kyungdo Han ◽  
Yoonji Lee ◽  
Seulki Kim ◽  
Seonhwa Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Diastolic Blood Pressure ◽  
Central Obesity ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Nutrition Examination Survey ◽  
Health And Nutrition ◽  
Age And Sex

Background. Little information is available on the association between parents’ metabolic syndrome (MetS) and adolescent offspring’s obesity in Korea. The aim of our study is to determine the association between parent’s metabolic syndrome and offspring’s obesity. Methods. The study data were obtained from the Korean National Health and Nutrition Examination Survey conducted during 2009–2016. In the present study, 3140 adolescents aged 12 to 18 years, their paternal pairs (PP, fathers = 2244), and maternal pairs (MP, mothers = 3022) were analyzed. Of these 3140 adolescents, 2637 had normal weight {age- and sex-specific body mass index (BMI) under the 85th percentile}, whereas 467 were overweight (age- and sex-specific BMI over the 85th percentile). Results. Offspring’s overweight and central obesity were associated with all components of the PP’s metabolic risk factors, including central obesity ( p < 0.001 ), systolic ( p < 0.001 ) and diastolic blood pressure ( p < 0.001 ), glucose intolerance ( p < 0.001 ), and triglyceride ( p < 0.002 ) and high-density lipoprotein levels ( p = 0.049 ). In addition, offspring’s overweight and central obesity were also associated with the metabolic risk factors of MP, including central obesity ( p < 0.001 ), systolic ( p < 0.001 ) and diastolic blood pressure ( p < 0.001 ), glucose intolerance ( p < 0.001 ), and triglyceride levels ( p < 0.001 ). In multivariate logistic regression analysis, offspring’s overweight was significantly and positively associated with parental central obesity (PP, adjusted odds ratio (OR) = 1.593; 95% confidence interval (CI): 1.192–2.128; MP, adjusted OR = 2.221, 95% CI: 1.755–2.812) and parental metabolic syndrome (PP, adjusted OR = 2.032; 95% CI: 1.451–2.846; MP, adjusted OR = 2.972, 95% CI: 2.239–3.964). As the number of parental metabolic risk factors increased, offspring’s risk for overweight and central obesity increased ( p for trends < 0.001). Conclusion. Parental metabolic syndrome was associated with obesity in 12- to 18-year-old offspring in Korea.

Abstract MP16: Reallocating Sedentary Behavior With Sleep or Physical Activity is Associated With Favorable Cardiovascular Health in the Multi-Ethnic Study of Atherosclerosis: MESA

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Charles German ◽  
Nour Makarem ◽  
Jason Fanning ◽  
Susan Redline ◽  
Tali Elfassy ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Sedentary Behavior ◽  
Diastolic Blood Pressure ◽  
Cardiovascular Health ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Ethnic Study ◽  
The Mean

Introduction: Sleep, sedentary behavior, and physical activity are each independently associated with cardiovascular health (CVH). However, many studies have investigated these relationships in isolation even though a change in any one given behavior will affect the time spent in the others. It is unknown how reallocating time in sedentary behavior with sleep or physical activity effects overall CVH in a diverse cohort of men and women at risk of cardiovascular disease (CVD). Hypothesis: Reallocating 30 minutes of sedentary time with sleep, light (LIPA), or moderate to vigorous physical activity (MVPA) is associated with more favorable overall CVH due to improvements in risk factors for CVD. Methods: Data for this analysis were taken from the Multi-Ethnic Study on Atherosclerosis (MESA) Sleep Ancillary Study. Eligible participants (n= 1718) wore Actiwatch accelerometers for 24 hours a day, and had at least 3 days of valid accelerometry. Time spent in sleep, sedentary behavior, LIPA, and MVPA was determined based on an established algorithm. The American Heart Association’s life simple 7 was used to represent the CVH score after excluding the physical activity component, with higher scores indicating more favorable CVH. All components were ascertained from MESA exam 5. Isotemporal substitution modeling was conducted to examine the effect of substituting 30 minutes of sedentary time for an equivalent amount of sleep, LIPA, or MVPA. Results: The mean age of participants was 68.3, 54.0% were female and 38.6% were white. The mean CVH score was 5.9 (95%CI: 5.8-6.0). On average, participants spent 499.3 minutes/day in sedentary time, 415.3 minutes/day in LIPA, 26.0 minutes/day in MVPA, and 388.2 minutes/day sleeping. Reallocating 30 minutes of sedentary time to sleep, LIPA, and MVPA was associated with a significantly higher CVH score [β(SE): 0.077(0.023), 0.039(0.017), and 0.485(0.065) respectively]. Reallocating 30 minutes of sedentary time to sleep was associated with lower BMI. Reallocating 30 minutes of sedentary time to LIPA was associated with higher diastolic blood pressure and total cholesterol, and lower BMI. Reallocating 30 minutes of sedentary time to MVPA was associated with lower systolic and diastolic blood pressure, and lower BMI. Conclusions: Our study demonstrates that sleep, LIPA, and MVPA are all positively associated with more favorable overall CVH and several key CVD risk factors. These findings underscore the importance of lifestyle modifications in improving CVH.

Abstract 54: Gender Differences In Blood Pressure Control Is Mediated By Age In United States Adults

Hypertension ◽  
2021 ◽  
Vol 78 (Suppl_1) ◽  
Author(s):  
Aayush Visaria ◽  
Fariha Hameed ◽  
Brinda Raval ◽  
Sumaiya Islam
Keyword(s):  
Blood Pressure ◽  
Gender Differences ◽  
Older Women ◽  
Survey Design ◽  
Age Groups ◽  
Medication Use ◽  
Pressure Control ◽  
Antihypertensive Medications ◽  
Health And Nutrition ◽  
Public Health Challenge

Introduction: Blood pressure (BP) control remains a major public health challenge. Little is known about the gender differences in BP control across the age spectrum. We determined the age-stratified associations between gender and uncontrolled HTN. Methods: We included adults ≥20 years who reported HTN diagnosis and antihypertensive medication use from the 1999-2018 National Health and Nutrition Examination Surveys. Mean BP was calculated as the average of 3 consecutive BP readings 30 seconds apart. Uncontrolled HTN was considered as BP ≥140/90. We used survey design-adjusted multivariable logistic regression to determine the odds of uncontrolled HTN in women vs. men, adjusting for demographic, sociobehavioral, metabolic, and comorbid factors. Results: Among 13,253 participants taking antihypertensive medications (mean age 57, 52% female, 71% White), 34% had HTN (35% women, 33% men). Upon stratifying by 10-year age groups, men had higher odds of uncontrolled HTN from age 20 to 49 years, followed by a period of insignificantly different odds of uncontrolled HTN from age 50-69 years (Table). Among participants ≥70 years, females had significantly higher adjusted odds of uncontrolled HTN. These associations persisted when using the 2017 ACC/AHA guidelines. Conclusion: Women have significantly higher odds (>20%) of uncontrolled HTN compared to men starting age 70. This may suggest that interventions to improve BP control in older women are warranted. The changes in the gender differences across the age spectrum warrant further evaluation.

scholarly journals Physical Activity and Sedentary Patterns among Metabolically Healthy Individuals Living with Obesity

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Marika de Winter ◽  
Brittany V. Rioux ◽  
Jonathan G. Boudreau ◽  
Danielle R. Bouchard ◽  
Martin Sénéchal
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Older Adults ◽  
Sedentary Behavior ◽  
Cardiometabolic Risk ◽  
Sedentary Time ◽  
Cardiometabolic Risk Factors ◽  
Behavior Patterns ◽  
Metabolically Healthy

Background. Some individuals living with obesity are free from typical cardiometabolic risk factors and are termed metabolically healthy obese (MHO). The patterns of physical activity and sedentary behaviors among MHO are currently unknown. Methods. This study includes 414 youth (12–18 years old), 802 adults (19–44 years old), and 1230 older adults (45–85 years old) living with obesity from the 2003-2004 or 2005-2006 NHANES cycles. Time spent in bouts of 1, 5, 10, 30, and 60 minutes for moderate-to-vigorous physical activity (MVPA) and sedentary time was measured objectively using accelerometers. Participants were categorized as MHO if they had no cardiometabolic risk factors above the identified thresholds (triglycerides, high-density lipoprotein cholesterol, systolic blood pressure, diastolic blood pressure, and glucose). Results. The proportion of MHO was 19%, 14%, and 12% in youth, adults, and older adults, respectively. MHO adults displayed a higher 1-minute bout of MVPA per day compared to non-MHO (p=0.02), but no difference was observed for MVPA and sedentary behavior patterns for youth and older adults. When adjusted for confounders, all bouts of sedentary behavior patterns in youth were significantly associated with being classified as MHO. Conclusion. This study suggests that greater sedentary time is associated with cardiometabolic risk factors in youth even if they are physically active.

Step-Defined Physical Activity and Cardiovascular Risk Among Middle-Aged Japanese: The National Health and Nutrition Survey of Japan 2006

2012 ◽  
Vol 9 (8) ◽  
pp. 1117-1124 ◽  
Author(s):  
Shigeru Inoue ◽  
Yumiko Ohya ◽  
Catrine Tudor-Locke ◽  
Nobuo Yoshiike ◽  
Teruichi Shimomitsu
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
National Health ◽  
Density Lipoprotein ◽  
Activity Measurement ◽  
Nutrition Survey ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Health And Nutrition

Background:Pedometers are becoming widely accepted for physical activity measurement. To use step data effectively, an index which categorizes steps/day by < 5000, ≥ 5000, ≥ 7500, ≥ 10,000, and ≥ 12,500 steps/day has been previously proposed. However, evidence is insufficient to validate this index compared with health outcomes. This study examined the association of steps/day categories with cardiovascular (CVD) risk.Methods:Cross-sectional data from the National Health and Nutrition Survey of Japan 2006, including 1166 men and 1453 women aged 40–64 years, were analyzed to calculate odds ratios (OR) for having CVD risk including overweight/obesity, blood pressure, high density lipoprotein cholesterol, hemoglobin A1c, and clustered risk factors by steps/day categories.Results:Among men, inverse gradient associations between steps/day categories and CVD risk (overweight/obesity, blood pressure, HbA1c, and clustered risk factors) were observed. Among women, those taking ≥ 5000 steps/day had substantially lower risk of overweight/obesity and high blood pressure compared with those taking < 5000 steps/day. However, additional decreases of OR by taking more steps were modest among women.Conclusions:CVD risk was generally lower with higher steps/day categories. Given the limitations of cross-sectional design, further studies, especially using longitudinal designs, are needed to precisely calibrate the association between steps/day and CVD risk.

scholarly journals Associations between physical activity, sedentary time and cardiovascular risk factors among Dutch children

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0256448 ◽  
Author(s):  
Gabrielle ten Velde ◽  
Guy Plasqui ◽  
Maartje Willeboordse ◽  
Bjorn Winkens ◽  
Anita Vreugdenhil
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Cardiovascular Risk Factors ◽  
Sedentary Time ◽  
Primary School Children ◽  
Z Score ◽  
Standardized Measures

Introduction Physical activity (PA) plays an important role in the prevention of cardiovascular diseases, especially in children. Previous studies which investigated the role of PA and sedentary time (ST) in cardiovascular disease used different measurements and found inconsistent results. The current study used recommended standardized measures and provides an overview of PA and ST among Dutch primary school children and their associations with cardiovascular risk factors. Methods 503 children (55% girls, mean age (± SD) 10 ± 1y) were included. PA (total PA, lightPA and moderate to vigorous PA (MVPA)) and ST were measured with the Actigraph GT3X accelerometer. PA in different domains was measured with the BAECKE questionnaire. Cardiovascular risk factors included BMI z-score, waist circumference, blood pressure (z-score) and estimated cardiorespiratory fitness (CRF) as measured with the 20 meter shuttle run test. Results Children spent 57 ± 20 min/day (8%) on MVPA and 42% of the children reached the MVPA guideline of 60 min/day. Total PA and MVPA (h/day) were negatively associated with BMI z-score (B = -0.452, p = 0.011) and waist circumference (B = -3.553, p = 0.011) and positively associated with CRF (B = 2.527, p = <0.001). ST was positively associated with BMI z-score (B = 0.108, p = 0.048) and waist circumference (B = 0.920, p = 0.033). No significant associations were found between total PA or PA intensities and blood pressure. Conclusion This study used standardized measures of PA and therefore created an accurate overview of PA, ST and their associations with cardiovascular risk factors. PA and ST were associated with BMI z-score, waist circumference and CRF. The findings emphasize the importance of promoting MVPA in children, but also highlight the potential benefits of reducing ST to improve cardiovascular risk factors. Trial registration ClinicalTrials.gov NCT03440580.

Combined associations between moderate to vigorous physical activity and sedentary behaviour with cardiometabolic risk factors in children

2013 ◽  
Vol 38 (5) ◽  
pp. 477-483 ◽  
Author(s):  
Jean-Philippe Chaput ◽  
Travis John Saunders ◽  
Marie-Ève Mathieu ◽  
Mélanie Henderson ◽  
Mark Stephen Tremblay ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Waist Circumference ◽  
Diastolic Blood Pressure ◽  
Sedentary Behaviour ◽  
Screen Time ◽  
Cardiometabolic Risk ◽  
Sedentary Time ◽  
Density Lipoprotein ◽  
Hdl Cholesterol

The objective of this study was to examine the combined associations between time spent in moderate- to vigorous-intensity physical activity (MVPA) and time spent sedentary in relation to cardiometabolic risk factors in a cohort of Canadian children. A cross-sectional study was conducted on 536 white children aged 8–10 years with at least 1 obese biological parent. Time spent in MVPA and sedentary behaviour over 7 days was measured using accelerometry and participants were stratified by tertiles. Daily screen time over 7 days was also self-reported by the child. Outcomes included waist circumference, systolic and diastolic blood pressure, fasting triglycerides, high-density lipoprotein cholesterol, and glucose concentrations. Analyses of covariance comparing tertiles of sedentary time/MVPA showed that higher levels of MVPA were associated with lower waist circumference, fasting triglycerides and diastolic blood pressure, and higher high-density lipoprotein (HDL) cholesterol, irrespective of sedentary time. In linear regression, MVPA was inversely associated with waist circumference and diastolic blood pressure and positively associated with HDL cholesterol, independent of covariates including sedentary time. In contrast, sedentary time was positively associated with diastolic blood pressure but after adjustment for MVPA the association was no longer statistically significant. Self-reported screen time was positively associated with waist circumference and negatively associated with HDL cholesterol independent of covariates including MVPA. Overall, a high level of MVPA was associated with reduced cardiometabolic risk in this sample of children, regardless of their amount of sedentary behaviour. The type of sedentary behaviour (i.e., screen time) might be more important than overall sedentary time in relation to cardiometabolic risk.

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