scholarly journals Evaluation of health-related quality of life in patients with Kashin-Beck disease using a new questionnaire:A cross-sectional study

Author(s):  
Zhankui Jin ◽  
Zhengming Sun ◽  
Xueyuan Wu ◽  
Ming Chen ◽  
Bo Yang ◽  
...  

Abstract Objective: Kashin-Beck disease (KBD) is an endemic deformable bone and joint disease, which seriously affects the quality of life (QOL) of patients. We tried to conduct a cross-sectional study of the QOL of KBD patients by a new KBD quality of life (KBDQOL) questionnaire.Methods: 252 KBD patients came from Northwest China, and 260 healthy people living in the same area as KBD patients served as the control group. KBDQOL questionnaire was used to evaluate the QOL of all objects.Results: The average score of physical functions, activity limitations, support of society, mental health and general health of KBD patients was significantly lower than that in control group. There was no statistical difference in economics between KBD patients and control group. The univariate analysis showed that age, height, weight status, education level and grade of KBD had a statistically significant effect on KBDQOL score. The results of multivariate analysis showed that grade of KBD was the influencing factor of physical function score; sex, age, height, grade of KBD and duration of symptoms were the influencing factors of activity restriction score; grade of KBD was the influencing factor of economic score, age and grade of KBD were influencing factors of general health.Conclusions: The QOL of patients with KBD was significantly lower than that of healthy people living in the same place. The KBDQOL questionnaire may be a promising tool for assessing the QOL of KBD patients.

2022 ◽  
Author(s):  
MING YI ◽  
Jing LI ◽  
Gang LIU ◽  
Weixi ZHANG ◽  
Ying WANG ◽  
...  

Abstract Background Facial appearance and expressions influence social interaction. However, few studies have reported on the stigma associated with spasms from facial dystonia. This study investigated the stigma and quality of life for these patients. Methods This cross-sectional study included 90 patients with facial dystonia (hemifacial spasm [HFS], blepharospasm [BSP], and blepharospasm-oromandibular dystonia [BOD]; 30 patients per group) and 30 individuals without dystonia (control group) from October 2019 to November 2020. All participants underwent stigma, quality of life, and mental health evaluations using seven questions related to stigma, the 36-item Short Form Health Survey, the 14-item version of the Hamilton Anxiety Scale (HAMA), and the 24-item version of the Hamilton Depression Scale. Results Nineteen patients (21.11%) felt stigmatized. Patients with BPS and HFS had more difficulty finding a job and were more susceptible to discrimination than healthy individuals. The role-physical and social function scores were significantly lower in the dystonia groups than in the control group. The vitality score of the BPS group and the mental health scores in the BPS and BOD groups were significantly less than those of the control group. The HAMA scores in the BPS and BOD groups were significantly higher than in the control group. Regression analysis demonstrated that the disease course influenced depression. Conclusion Enacted stigma from a negative public attitude may be the main factor triggering stigma in patients with facial dystonia, with detrimental effects on psychosocial outcomes, including social rights, quality of life, and mood.


2013 ◽  
Vol 64 (2) ◽  
pp. 100-106
Author(s):  
Tinatin Gagua ◽  
Tkeshelashvili Besarion ◽  
David Gagua

Objective: The study aimed to measure the effect of primary dysmenorrhea on the quality of life of female adolescents living in Tbilisi, Georgia, and to compare Quality of Life (QoL) with healthy controls.Materials and methods: Cross-sectional study of 424 women aged 14-20, living in Tbilisi, Georgia, coming from academic and research institutions. The women were divided into those suffering dysmenorrhea (exposure group) and those without pain (control group). Reproductive history, demographic features, menstrual pattern, severity of dysmenorrhea and quality of life using the generic instrument EQ-5D, were measured. The Independent T student test was used for group comparison.Results: The group with dysmenorrhea (276) showed a lower Quality of Life score of 0.69 ± 0.20 vs. 0.94 ± 0.10 in the control group (p = 0.000); the Quality of Life VAS was also lower at 74.38 ± 17.83 vs. 87.02 ± 12.03 (p = 0.000). Of the subjetcs with primary dismenorrhea, 56.6% reported school absenteeism due to pain.Conclusion: Primary dysmenorrhea is a common problem in the adolescent population of Tbilisi, Georgia. The results of this study demonstrate that adolescents with primary dysmenorrhea in Georgia experience significantly lower physical and psychosocial health-related QoL than their healthy peers.


2019 ◽  
Author(s):  
Lise Sofie Bislev ◽  
Lene Langagergaard Rodbro ◽  
Lars Rolighed ◽  
Tanja Sikjaer ◽  
Lars Rejnmark

2017 ◽  
Vol 41 (S1) ◽  
pp. S238-S238
Author(s):  
M. Holubova ◽  
J. Prasko ◽  
M. Ociskova ◽  
M. Marackova ◽  
A. Grambal ◽  
...  

BackgroundSelf-stigma is a maladaptive psychosocial phenomenon that may disturb many areas of patient's life and have the negative impact on their quality of life. The present study explored the association between self-stigma, quality of life, demographic data, and the severity of symptoms in patients with depressive disorder.MethodPatients, who met ICD-10 research criteria for depressive disorder, were enrolled in the cross-sectional study. All probands completed these measurements: the Quality of Life Satisfaction and Enjoyment Questionnaire (Q-LES-Q), the Internalised Stigma of Mental Illness Scale (ISMI), demographic questionnaire, and the severity of the disorder measured by objective and subjective Clinical Global Impression severity scales (CGI).ResultsEighty-one depressive patients (with persistent affective disorder – dysthymia, major depressive disorder or recurrent depressive disorder) and 43 healthy controls contributed to the study. Comparing with the healthy control group, there was a lower quality of life in patients with depression. The level of self-stigma correlated positively with total symptom severity score and negatively with the quality of life. Multiple regression analysis discovered that the overall rating of objective symptoms severity and self-stigma were significantly associated with the quality of life.ConclusionsPresent study suggests the lower quality of life in outpatients with depressive disorder in comparison with healthy controls, and the negative impact of self-stigma level on quality of life in patients suffering from depressive disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Author(s):  
Agnieszka Nawrat-Szołtysik ◽  
Zuzanna Miodońska ◽  
Laura Piejko ◽  
Bogna Szołtys ◽  
Monika Błaszczyszyn ◽  
...  

Background: The quality of life in osteoporosis is studied for men rather than for women. Aim of the study was to determine how bone mass density (BMD) relates to life quality components and the severity of pain felt by men affected by osteoporosis. Methods: Presented research is a cross-sectional study. The cohort of 62 men aged 65 to 85 years was divided into a group with osteoporosis (N = 27) and a group without osteoporosis (N = 35). The participants’ quality of life was measured with the Qualeffo41 Questionnaire, BMD was quantified by densitometry, and pain intensity was assessed on the Visual Analogue Scale. Results: We found that lower BMD was strongly correlated to participants’ quality of life (r = −0.72), especially the quality of leisure and social activities (r = −0.66), general health perception (r = −0.59), and mobility (r = −0.57). Pain significantly affected general health perception in older men with osteoporosis. General health assessment and pain were highly correlated with each other (r = 0.888). Conclusion: BMD and the overall quality of life of the study participants were related to each other. The strongest relationship occurred between reduced BMD and leisure and social activities component. The pain significantly affected participants’ general health perception. The results may be employed to create new prophylactic strategies to improve life quality in men with osteoporosis.


2020 ◽  
Author(s):  
Zaki Hakami ◽  
Hye Soo Chung ◽  
Seham Moafa ◽  
Hadia Nasser ◽  
Hajar Sowadi ◽  
...  

Abstract Background Fake braces have become popular as fashionable appliances in some parts of the world, however, there is a scarcity of information about their effects on various aspects of quality of life. Therefore, our aim was to investigate the effects of fake braces on oral health related quality of life (OHRQoL).Methods A cross-sectional study was carried out with data collection from a Google form questionnaire distributed in Saudi Arabia via various forms of social media over a period of four months. OHRQoL was assessed using the validated Arabic version of the Oral Health Impact Profile-14 (OHIP-14) questionnaire. Fake braces group included respondents who had braces installed for fashion purposes only. Therapeutic braces group included subjects who were wearing braces to treat any malocclusion problems. Control group included participants who did not have any kind of braces. People who had previously completed orthodontic treatments were excluded from the study. The negative impacts were divided into seven domains and a total OHIP score was calculated. Statistical analyses and data illustration were performed with SPSS Statistics (v. 25).Results A total of 1167 people voluntarily participated in the study. More than 60% of the participants were in the control group while 30% had conventional braces for therapeutic reasons and less than 5% had fashion braces under investigation. Sociodemographic distributions varied among the groups and the majority of the subjects in fake braces group had education below the university level with family income of less than average. There were no significant group differences in total OHIP scores. Physical pain was the most frequently reported complaint by all subjects and was the highest in the therapeutic braces group. People with fake or therapeutic braces reported significantly higher functional limitation and physical disability than the control. Yet, fashion braces group reported significantly lower psychological discomfort and disability compared to the therapeutic braces or control groups.Conclusions The illustrated effects of fake braces on OHRQoL in this study suggests the need to study the role of social media and educate the public on the use of braces to minimize the negative effects experienced by individuals.


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