scholarly journals The Prevalence of Mycobacterium Tuberculosis Using Gene Xpert Among Tuberculosis Suspected Patients in Gedeo Zone, Southern Ethiopia

Author(s):  
Kuma Urgeya Diriba ◽  
Gemechu Churiso

Abstract Background Tuberculosis (TB) is a communicable disease remains a major global health problem and the leading cause of death from a single infectious agent. Even though many of the WHO recommended TB control strategy was implemented; there is still a major gap in TB case detection and treatment. This study aimed to determine the prevalence of Mycobacterium tuberculosis among presumptive TB patients in Gedeo Zone, Southern Ethiopia. Methods A cross-sectional study was conducted on 384 TB suspected patients in Gedeo Zone from February to July 2021. Data were collected using a pretested structured questionnaire. Laboratory examination was processed using Xpert-MTB/RIF assay. Data entry was made using Epi info version 7 and analyzed by SPSS version 24. Logistic regression models were used to determine the risk factors. Results Out of 384 study participants suspected with TB, M tuberculosis was isolated from 103 giving an overall prevalence of 26.8%. Males (AOR) = 1.95; 95% CI 1.56-2.65, P=0.01) were more likely to develop TB than females. Study participants who were illiterate (AOR 2.10; 95% CI 1.17-2.51, p=0.014) were more likely to develop TB than the educated one. Cigarette smokers (AOR 2.89; 95% CI 2.10-3.84, p=0.01), khat chewers (AOR 2.86; 95% CI 1.28-3.79, p=0.01), vaccination (AOR 0.52; 95% CI 0.21-0.88, p=0.02), close contact (AOR 3.42; 95% CI 2.24-4.50, p=0.01) and being positive for HIV (AOR 2.01; 95% CI 1.07-3.52, 0.01) were more likely to develop TB. Conclusion Despite implementation of national and international TB control strategies, TB still remains one of the major public health problems in the country especially in the study area. The high prevalence of MTB was reported different risk groups. Early case detection and management of TB should be given special attention to strengthen and an appropriate control and prevention methods to reduce the emergence and increasing of MTB cases.

2021 ◽  
Vol 9 ◽  
pp. 205031212110455
Author(s):  
Degineh Belachew Andarge ◽  
Tariku Lambiyo Anticho ◽  
Getamesay Mulatu Jara ◽  
Musa Mohammed Ali

Objective: Multidrug-resistant Mycobacterium tuberculosis is a public health threat in resource-limited countries where it is easily disseminated and difficult to control. The aim of this study was to determine the prevalence of tuberculosis, rifampicin-resistant/multidrug-resistant Mycobacterium tuberculosis, and associated factors among presumptive tuberculosis cases attending the tuberculosis clinic of Adare General Hospital located in Hawassa city. Methods: A hospital-based cross-sectional study was conducted among 321 tuberculosis suspected patients from April to July 2018. Socio-demographic, environmental, and behavioral data were collected using a structured questionnaire. Sputum specimens were analyzed using GeneXpert. Data entry was made using Epi info version 7 and analyzed by SPSS version 20. Logistic regression models were used to determine the risk factors. A p-value less than 0.05 was taken as a cut point. Results: In this study, the prevalence of Mycobacterium tuberculosis was 98 (30.5%) with 95% confidence interval (25.5–35.8), and the prevalence of rifampicin-resistant/multidrug-resistant Mycobacterium tuberculosis among the 98 Mycobacterium tuberculosis confirmed cases was 4 (4.1%). The prevalence of rifampicin-resistant/multidrug-resistant Mycobacterium tuberculosis among the tuberculosis suspected patients was 1.24%. Participants who had a history of treatment with anti-tuberculosis drugs were more likely to develop rifampicin-resistant/multidrug-resistant Mycobacterium tuberculosis. Conclusions: This study identified relatively high rifampicin-resistant/multidrug-resistant Mycobacterium tuberculosis among tuberculosis suspected patients in the study area. Early detection of drug-resistant Mycobacterium tuberculosis should be given enough attention to strengthen the management of tuberculosis cases and improve direct observation therapy short-course and eventually minimize the spread of rifampicin-resistant tuberculosis strain in the community.


Author(s):  
Dhanasekar Gurupatham ◽  
Jeevithan Shanmugam

Background: Alcohol use is associated with serious public health problems thereby raising the global morbidity and mortality. The main aim of this study is to estimate the prevalence of alcoholism and its co morbidity pattern among urban adult population in Salem district, Tamil Nadu.Methods: A community based cross-sectional study was carried out among urban adult population in Salem district involving 493 participants. Convenient sampling method was used. Informed consent was obtained from each participant and information was collected by using a predesigned structured questionnaire. Microsoft Excel 2007 was used for data entry and SPSS version 24 was used for data analysis.Results: It was found from the study that the prevalence of alcoholism was high. Alcohol use in any form was found in 38% of the study participants. 8% of the participants confessed that alcohol is an eye opener to them. 6% of the participants lost their job and 15% of the participants were hospitalised due to alcohol.Conclusions: The study showed higher prevalence of alcohol use among urban adult population in Salem district. Awareness about the ill effects of alcoholism among the population and necessary rehabilitation will help to reduce alcoholism consumption and its related disorders.


Author(s):  
Birhannu Jikamo ◽  
Temesegen Woelamo ◽  
Mekonen Samuel

Abstract Abstract Background: In 2009, in Hadiya zone reported that establishment of Urban Health Extension Program (UHEP) which is subsequent declaration of after the country of Ethiopia. Major contribution of the declared UHEP is to provide accessible service to the potentially vulnerable groups of <5children pregnant women. Therefore, the aim of this study was to assess the utilization and associated factors of the urban health extension program services in Hossana Town, Hadiya Zone, southern Ethiopia, 2018 Methods: we conducted community based cross-sectional study in Hossana town, Hadiya Zone southern Ethiopia. Households were recruited by using systematic random sampling technique and study participants also by using random sampling techniques. A total of 403 study participants were participated in this study. Strength of measure of association between explanatory variables with outcome variable reported using the Odds Ratio (OR) with 95% confidence interval. Bivariate and multivariate binary logistic regression analysis was performed to identify predictors. P-value < 0.05 used to identify factors significantly associated with outcome variable. Results: Out of 403 households, 397(98.5%) of response rate obtained. The mean score of community knowledge about the utilization of urban health extension program service (UHEP) was 2.352 (SD ±1.156. Regarding knowledge towards UHEP, of 166 (42%) of the respondents had good knowledge towards UHEP service while 231 (58%) had poor knowledge towards UHEP service utilization. The total number of households which graduated as a model family was 79 (19.9%). In the adjusted multivariate model, those respondents in the age group of 36-45 year were 3.73 times(AOR = 3.73; 95% CI:1.04-3.37) more likely to be utilized health extension program services as compared with those respondents in the age group of 18-24year. Those households which graduated as a model family were 2.2 times (AOR = 2.18; 95% CI: 1.36- 3.51) higher odds of utilized health extension program service as compared with those households which didn’t graduated as a model family. Conclusions: The coverage of utilization of urban health extension program service was low in the study setting compared with previous study. There were also identified predictors that were associated with utilization of urban health extension program service.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Wondimagegn Paulos Kumma ◽  
Yusuf Haji ◽  
Junayde Abdurahmen ◽  
Yohannes Mehretie Adinew

Background. Universal use of iodized salt is a simple and inexpensive method to prevent and eliminate iodine deficiency disorders like mental retardation. However, little is known about the level of adequately iodized salt consumption in the study area. Therefore, the study was aimed at assessing the proportion of households having adequately iodized salt and associated factors in Wolaita Sodo town and its peripheries, Southern Ethiopia. Methods. A cross-sectional study was conducted from May 10 to 20, 2016, in 441 households in Sodo town and its peripheries. Samples were selected using the systematic sampling technique. An iodometric titration method (AOAC, 2000) was used to analyze the iodine content of the salt samples. Data entry and analysis were done using Epi Info version 3.5.1 and SPSS version 16, respectively. Result. The female to male ratio of the respondents was 219. The mean age of the respondents was 30.2 (±7.3 SD). The proportion of households having adequately iodized salt was 37.7%, with 95% CI of 33.2% to 42.2%. Not exposing salt to sunlight with [OR: 3.75; 95% CI: 2.14, 6.57], higher monthly income [OR: 3.71; 95% CI: 1.97–7.01], and formal education of respondents with [OR: 1.75; 95% CI: 1.14, 2.70] were found associated with the presence of adequately iodized salt at home. Conclusion. This study revealed low levels of households having adequately iodized salt in Wolaita Sodo town and its peripheries. The evidence here shows that there is a need to increase the supply of adequately iodized salt to meet the goal for monitoring progress towards sustainable elimination of IDD.


2021 ◽  
Vol 4 (4) ◽  
pp. 11-23
Author(s):  
Getachew Roba Agegnew ◽  
Seyoum Robo Gebremariam ◽  
Abera Haile Adello ◽  
Yasin Abafita Abawari ◽  
Abiyot Mamo Mergia ◽  
...  

The severe acute respiratory syndrome coronavirus and resultant coronavirus disease (COVID-19) have evolved into a pandemic, requiring persons around the world to attend to rapidly changing messages about public health and take immediate actions. Related to this, community’s awareness toward the preventive practice of coronavirus is assessed. Hence, the purpose of this was to investigate the awareness and preventive practice among communities. Cross-sectional survey design was conducted among 400 participants. Simple random sampling, technique particularly lottery method was used to select the study participants. Data was collected by using questionnaire and observation. After the data was collected, data entry and analysis were done using SPSS version 26. Hence, data gathered using questionnaire and observation was computed by using simple descriptive statistics (percentage and frequencies). Regarding awareness level of communities 61% of respondents aware that covid-19 transmits from victim by hand shaking and close contacts. And hence, 37.8% of participants aware that awareness creation was done by health organization service centers. And hence, the findings in this study revealed that community’s awareness was high on each specific aspect of COVID-19 among the study participants. Communities are not still totally pay attention to aware about COVID 19, crisis. According to finding in this research communities wash their hand in order to prevent covid-19 better than the previous. Kaffa zone as well as stakeholders should have to provide ample information for all communities including urban and rural societies to aware about COVID-19 and practice how to prevent. 


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Anteneh Fikrie ◽  
Yonatan G. Mariam ◽  
Elias Amaje ◽  
Henok Bekele

Abstract Background Globally, at least 1 billion people have a vision impairment that could have been easily prevented or easily treated. Cataract is the leading preventable and most treatable causes of blindness and bilateral low vision among adults. Despite being the leading cause of preventable and most treatable blindness, the lack of knowledge about the disease and its option of treatment is still a major barrier in reducing the blindness owing to cataract in the developing countries particularly in Ethiopia. Hence, the aim of this study is to determine the level of knowledge about cataract and associated factors among adults in Yirgalem Town, Sidama National Regional State, Southern Ethiopia, 2020. Methods A community-based cross-sectional study design was conducted among randomly selected 599 adult’s age 18 years and above from May 10–30, 2020. A multi-stage sampling technique was used to select the study participants. Data were collected using pre-tested and structured face-to-face interview questionnaires. The collected data were entered to Epi data version 3.1 and then exported to SPSS version 21 for analysis. Bi-variable and multivariable logistic regression was used to identify associated factors of knowledge about cataract. Adjusted Odds Ratio (AOR) together with 95% Confidence Interval (CI) was used to declare the statistical association between dependent and independent variables. Results Of the total study participants, 379 (64.7%), [(95% CI: 60.7–68.6%)] of them had good knowledge about cataract. Age (≥40 years) [AOR = 2.29(95% CI 1.18–4.44)], Elementary school completed [AOR = 2.31(95% CI 1.30–4.10)], High school & above [AOR = 5.55(95% CI 2.81–10.89)], governmental and non-governmental employed [AOR = 5.62 (95% CI 2.78–11.38)], Merchant [AOR = 1.72(95% CI 1.03–2.88)], Positive Attitude [AOR = 3.85(95% CI 2.94–6.47)] were positively significantly associated with knowledge about cataract. Whereas, rural residence [AOR = 0.19 (95% CI: 0.12–0.31)] was negatively associated with knowledge about cataract. Conclusions More than one third of the participants still had poor knowledge about cataract. This implies that health facilities should be engaged and raises the awareness of the community and empowers people about eye care needs.


Author(s):  
Singh Lal Divakar ◽  
Shiv Prakash ◽  
Khurshid Parveen ◽  
Richa Singh

Background: A disorder that has no apparent symptoms but later results in serious health problems can pose great threat to the health of people. Hypertension is such a major non communicable disease (NCD) and affects about 20% of the population in most communities. Hypertension has a major hand in causation of coronary artery diseases, stroke and various other vascular complications, and renal disorders. The study was done with objective to assess prevalence of hypertension of male which were ≥30 years in Urban and Rural Prayagraj.Methods: A community based cross-sectional study was carried out in Prayagraj District. Study participants were 620 males, 310 urban and 310 rural of age equal or above 30 years and study sampling technique were two stage random sampling. The data was collected by using predesigned, pretested, semi structured questionnaire and analyzed by using SPSS 23.0 version.Results: Prevalence of hypertension was 41.13%. A statistically significant association of hypertension was found with hypertension and BMI, lifestyle, salt consumption, dietary preference and amount of vegetable/fruit each.Conclusions: A high prevalence was found in this study when compared with others study. BMI, lifestyle, salt consumption, dietary preference and amount of vegetable were found to be significantly association risk factors for hypertension among males in Allahabad district.


2021 ◽  
Author(s):  
Yadessa Tegene Woldie ◽  
Selamawit Mengesha Bilal ◽  
Rianne Tanis ◽  
Babette Spaargaren ◽  
Alemayehu Toma ◽  
...  

Abstract Background: HIV requires life-long adherence to treatment and diet, also to avoid chronic co-morbidity. Self-management is widely recognized as an essential part of care for people with chronic disease. We aimed to quantify the prevalence of co-morbidity among adult HIV patients and their self-management skills.Methods: An institutional based cross sectional study was conducted from May to June 2019. We selected a total of 520 adult HIV patients, attending antiretroviral therapy clinics in three Hospitals in Southern Ethiopia. Data were collected at routine care consultations by nine trained nurses using a pre-tested structured questionnaire. Result: The mean age of the study participants was 38.7±9 years. Prevalence of diabetes and Hypertension was 1.5% and 9.4%, respectively. Being older, overweight, and obese was significantly associated with chronic comorbidity. The total score of HIV Self-management was 42±3.92 out of 60. The least mean score (1.69±0.9) was seen in the social support domain of HIV self-management.Conclusion: The prevalence of diabetes and hypertension was relatively low in our population. Self-management skills seem to be low, but many aspects of self-management are poorly understood in Ethiopia (low-income) setting.


2020 ◽  
Author(s):  
Aziza Shaibu Machenje ◽  
Stephen M. Kibusi ◽  
Nyasiro Gibore ◽  
Athanase Lilungulu ◽  
Fabiola V. Moshi

Abstract Background : Hypertensive disorders of pregnancy, including preeclampsia and eclampsia are the major health problem and the main cause of the maternal and perinatal morbidity and mortality in Tanzania. The aim of this study was to assess knowledge and myths about preeclampsia and eclampsia and its influence in Antenatal Clinics (ANC) utilization among expecting couples in Mtwara region.Method : A community based cross-sectional analytical study conducted in Mtwara Region, a random sampling procedure was employed to obtain a sample size of 384 couples with a total of 768 participants (male=384 and female =384). Interviewer structured questionnaire was used for data collection and Statistical package for social science (SPSS v.20) software was used for data entry and analysis. Descriptive statistics, cross tabulation, Principal component analysis (PCA) was conducted and inferential statistics were used to test association between variables obtained.Results: Among 768 participants, only 292(38%) had adequate knowledge about preeclampsia and eclampsia. More than a half 396(51.6%) of study respondents had weak myths while 372(48.4%) had strong myths on pre-eclampsia and eclampsia. Furthermore 492(64%) had adequate antenatal care utilization. Study participants who had adequate knowledge on pre-eclampsia and eclampsia were almost 3 times more likely to utilize antenatal care services (AOR = 2.827; CI = 1.719 – 4.651; p<0.001). Study participants who had weak myth on pre-eclampsia and eclampsia were less likely to have adequate antenatal care attendance (AOR =0.370; CI = 0.0229-0.599; p< 0.001)Conclusion : The overall knowledge of preeclampsia and eclampsia was low. Majority of the female had adequate antenatal service utilization. Majority of respondents had weak myths. Government and stakeholders should ensure that community is equipped with knowledge about preeclampsia and eclampsia and the available Myths should be dispelled.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Biniam Wondale ◽  
Kwon Keehwan ◽  
Girmay Medhin ◽  
Takele Teklu ◽  
Temesgen Mohammed ◽  
...  

Abstract Background Tuberculosis (TB) is caused by Mycobacterium tuberculosis complex (MTBC). Mapping the genetic diversity of MTBC in high TB burden country like Ethiopia is important to understand principles of the disease transmission and to strengthen the regional TB control program. The aim of this study was to investigate the genetic diversity of Mycobacterium tuberculosis complex (MTBC) isolates circulating in the South Omo, southern Ethiopia. Methods MTBC isolates (N = 156) were genetically analyzed using spacer oligotyping (spoligotyping) and mycobacterial interspersed repetitive unit-variable number of tandem repeat (MIRU-VNTR) typing. Major lineages and lineages were identified using MTBC databases. Logistic regression was used to correlate patient characteristics with strain clustering. Results The study identified Euro-American (EA), East-African-Indian (EAI), Indo-Oceanic (IO), Lineage_7/Aethiops vertus, Mycobacterium bovis and Mycobacterium africanum major lineages in proportions of 67.3% (105/156), 22.4% (35/156), 6.4% (10/156), 1.9% (3/156), 1.3% (2/156) and 0.6% (1/156), respectively. Lineages identified were Delhi/CAS 23.9% (37/155), Ethiopia_2 20.6% (32/155), Haarlem 14.2% (22/155), URAL 14.2%(22/155), Ethiopia_3 8.4% (13/155), TUR 6.5% (10/155), Lineage_7/Aethiops vertus 1.9% (3/155), Bovis 1.3% (2/155), LAM 1.3% (2/155), EAI 0.6% (1/155), X 0.6% (1/155) and Ethiopia H37Rv-like strain 0.6% (1/155). Of the genotyped isolates 5.8% (9/155) remained unassigned. The recent transmission index (RTI) was 3.9%. Orphan strains compared to shared types (AOR: 0.09, 95% CI: 0.04–0.25) were associated with reduced odds of clustering. The dominant TB lineage in pastoral areas was EAI and in non-pastoral areas was EA. Conclusion The epidemiological data, highly diverse MTBC strains and a low RTI in South Omo, provide information contributing to the TB Control Program of the country.


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