scholarly journals Translation and Validation of M.D. Anderson Symptom Inventory-Thyroid Cancer Module in Chinese Thyroid Cancer Patients: A Cross-Sectional and Methodological Study

Author(s):  
Ziyi Hu ◽  
Juxiang Gou ◽  
Ming Cai ◽  
Yueer Zhang

Abstract Aim To translate and validate the Chinese version of the MDASI-THY among thyroid cancer patients. Background The M.D. Anderson Symptom Inventory-Thyroid Cancer module (MDASI-THY) is one of well-validated instruments for thyroid-specific symptom assessment. To date, the instrument has not been used in China. Methods After standard forward- and back-translation procedures, two instruments, the Chinese version of MDASI-THY and the European Organization for Research and Treatment of Cancer QLQ C30, were answered by 309 thyroid patients. The content, convergent discriminant validity and reliability of the MDASI-THY were evaluated. The Standards for Reporting Diagnostic Accuracy Studies (STARD) was used as reporting checklist. Results S-CVI and I-CVI of the instrument were over 0.80. There were significant relationships between MDASI-THY and EORTC QLQ-C30 (p<0.001). Symptoms were severer for patients underwent surgical treatment. The Cronbach’s alpha was 0.966 (between 0.954 and 0.827 for subscales). Most symptom items had moderate to high interitem correlations. Conclusions The Chinese version of MDASI-THY demonstrated favorable validity and reliability. It can be used in development of symptom management program in thyroid cancer patients in China. Relevance to clinical practice: Nurse can apply this instrument to assess Chinese thyroid cancer patients to increase the understanding of their symptom experience, resulting in a better symptom management.

BMJ Open ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. e025378
Author(s):  
Jing Zhang ◽  
Liebin Zhao ◽  
Deyu Zhao ◽  
Zhimin Chen ◽  
Shenghui Li ◽  
...  

ObjectiveThe limited existing asthma control questionnaires that are available for children 5 years of age or younger in China mostly assess only the impairment domain of asthma control. Here, the English version of the Test for Respiratory and Asthma Control in Kids (TRACK) was translated into Chinese and validated for its application in asthma control in preschool children.DesignProspective validation study.Setting and participantsA total of 321 Chinese preschool children suffering from asthma completed the study from December 2017 to February 2018.MethodThe TRACK translation into Chinese employed the translation and back translation technique. The caregivers of the preschool children with asthma symptoms completed TRACK during two clinical visits over 4–6 weeks. Moreover, the physicians completed a Global Initiative for Asthma (GINA)-based asthma control survey at both visits. The utility of TRACK for assessing the change in asthma control status and its reliability and discriminant validity were evaluated.ResultsThe Chinese version of TRACK showed internal consistency reliability values of 0.63 and 0.71 at each visit, respectively (Cronbach’s α). The test–retest reliability was 0.62 for individuals whose GINA-based assessment results were the same at both visits (n=206). The TRACK scores for the children in the various asthma control categories were significantly different (p<0.001). Children recommended for increased treatment by the physicians had lower TRACK scores than those recommended for no change in treatment or decreased treatment (p<0.001).ConclusionThe study verifies the validity and reliability of the Chinese version of TRACK. Changes in the TRACK scores effectively reflected the level of asthma control in preschool children and guided further treatment strategies.Trial registration numberNCT02649803


2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Juliana Alvares Duarte Bonini Campos ◽  
Maria Cláudia Bernardes Spexoto ◽  
Wanderson Roberto da Silva ◽  
Sergio Vicente Serrano ◽  
João Marôco

ABSTRACT Objective To evaluate the psychometric properties of the seven theoretical models proposed in the literature for European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), when applied to a sample of Brazilian cancer patients. Methods Content and construct validity (factorial, convergent, discriminant) were estimated. Confirmatory factor analysis was performed. Convergent validity was analyzed using the average variance extracted. Discriminant validity was analyzed using correlational analysis. Internal consistency and composite reliability were used to assess the reliability of instrument. Results A total of 1,020 cancer patients participated. The mean age was 53.3±13.0 years, and 62% were female. All models showed adequate factorial validity for the study sample. Convergent and discriminant validities and the reliability were compromised in all of the models for all of the single items referring to symptoms, as well as for the “physical function” and “cognitive function” factors. Conclusion All theoretical models assessed in this study presented adequate factorial validity when applied to Brazilian cancer patients. The choice of the best model for use in research and/or clinical protocols should be centered on the purpose and underlying theory of each model.


2021 ◽  
Author(s):  
Ting Zhang ◽  
Ying-ying Zheng ◽  
Zhi-rong Yang ◽  
Qiuling Shi ◽  
Xin Shelley Wang ◽  
...  

Abstract Background: Gynecologic cancers are among the most prevalent malignancies in China, and millions of gynecologic cancer patients are expected to undergo open abdominal surgery as initial treatment. The tumor- and surgery-related symptom burden are not well studied owing to a lack of a standardized and validated assessment tool in Chinese. The study was to translate and validate the MD Anderson Symptom Inventory for measuring perioperative symptom burden in gynecologic cancer patients (MDASI-PeriOp-GYN) and examine the utility of the Chinese version.Methods: The MDASI-PeriOp-GYN was translated in a stepwise manner. First, two native speakers independently translated the 9 PeriOp-GYN symptom items. Then the 9 items were translated back into English by another two bilingual translators. After discussion and revision, the four translators reached an agreement. The finalized Chinese version was administered to women with three common gynecologic cancer types (cervical, ovarian, and endometrial cancers) recruited from the gynecological oncology department of Sichuan Cancer Hospital & Institute between July and October 2019. Reliability and validity of the translated version were assessed. Results: Overall, 324 women with gynecologic cancers were enrolled. Cronbach’s α values were 0.826 and 0.735 for the symptom severity and interference scales, respectively. Test-retest reliability values were 0.885, 0.873, and 0.914 for the symptom severity, PeriOp-GYN, and interference scales, respectively. Significant correlations were found between the MDASI-PeriOp-GYN-C and EORTC QLQ-C30 along with the QLQ-OV28 module (-0.608–0.871, P<0.001). Known-group validity was supported by significant differences in the scores of the four scales grouped by time intervals, surgery type, and functional status (all P<0.01). Conclusions: The MDASI-PeriOp-GYN-C is a valid and reliable tool for measuring symptoms in Chinese patients undergoing surgery for gynecologic cancers. The tool could be used in clinical practice and clinical trials to instantly gather patients’ health and quality of life data.


2018 ◽  
Vol 32 (3) ◽  
pp. 255-275 ◽  
Author(s):  
Ümmühan Aktürk ◽  
Behice Erci

Purpose:The purpose of this study was to determine the effect of Watson’s Human Caring Model on the meaning of life and symptom management in cancer patients undergoing chemotherapy.Design:The study was conducted using a real test model featuring a pretest and posttest and a control group.Methods:The sample consisted of 158 adult cancer patients (79 in both the experimental and control groups). The sample size was determined and the participants were allocated to groups using power analysis and a random sampling method. For the pretest, both groups completed an introductory questionnaire, the Life Attitude Profile, and the General Symptom Inventory. Then, the experimenter visited the experimental group patients’ homes three times, at 2-week intervals, to provide nursing care based on Watson’s model. Finally, after 8 weeks, a posttest was conducted by having both groups complete the Life Attitude Profile and General Symptom Inventory once again.Results:In the experimental group, the mean total posttest score for the Life Attitude Profile was determined to be 164.21 ± 36.5, and the mean total General Symptom Inventory score was 55.06 ± 13.19; however, in the control group, the mean total Life Attitude Profile score was 127.31 ± 10.61 and the mean total General Symptom Inventory score was 136.91 ± 16.20. The mean differences between the groups were statistically significant (p < .001).Implications for Practice:Care based on Watson’s model increases the sense of meaning in life and decreases symptom levels for patients undergoing chemotherapy.


2019 ◽  
Vol 57 (4) ◽  
pp. 820-827
Author(s):  
Ren-wang Chen ◽  
Sheng-li Yang ◽  
Zhong-yu Xu ◽  
Miao Peng ◽  
Meng-ni Chen ◽  
...  

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Haiyan Tang ◽  
Huihua Xiong ◽  
Lingchao Deng ◽  
Andreas Maercker ◽  
Jun Zhang ◽  
...  

Abstract Background After the new definition of adjustment disorder (AjD) by the International Classification of Diseases-11(ICD-11), AjD has attracted more and more attention. Adjustment disorder new module-20 (ADNM-20), which is used to diagnose AjD, has been verified in some countries, but it has not been verified in China. As a result, the purpose of this study was to investigate the validity and reliability of the Chinese version of the Adjustment disorder new module-20 (ADNM-20) in female breast cancer patients. Methods The ADNM-20 translated into Chinese employed the translation and back translation technique. Three hundred fifty four newly diagnosed (< 1 year) female breast cancer patients were recruited from Tongji Hospital and Hubei Cancer Hospital in Hubei, China. The patients completed the self-report questionnaire including demographic characteristics and the scale ADNM-20. Data on psychometric properties were evaluated in terms of internal consistency, item-total correlations, test-retest reliability, and factorial validity. Results ADNM-20 core symptoms included 8 items and two factors, which were extracted by using exploratory factor analysis (EFA). It could explain 61.74% of the total variance. ADNM-20 accessory symptoms including 12 items and four factors, which were extracted by using EFA. It could explain 68.34% of the total variance. Cronbach’s α coefficient for ADNM-20 was 0.93, split-half reliability was 0.87, and the test-retest correlation coefficient was 0.74. The correlation coefficient between each subscale was ranged from 0.53 to 0.71 (P < 0.01), while the correlation coefficient between the subscales and total scale was ranged from 0.79 to 0.89 (P < 0.01). Conclusions The study verified the validity and reliability of the Chinese version of ADNM-20. It is applicable to measure the prevalence of adjustment disorder in the breast cancer population.


Oncology ◽  
2008 ◽  
Vol 76 (1) ◽  
pp. 59-68 ◽  
Author(s):  
Ibrahima Gning ◽  
Peter C. Trask ◽  
Tito R. Mendoza ◽  
Margaret T. Harle ◽  
Karla A. Gutierrez ◽  
...  

2021 ◽  
Author(s):  
Renwang Chen ◽  
Qiong Wang ◽  
Ting Hu ◽  
Jue Wang ◽  
Yu-xiu Xie ◽  
...  

Abstract Purpose To validate and use the Chinese Version of the M. D. Anderson Symptom Inventory (MDASI-C) to assess the symptom burden of breast cancer patients of China. And to reveal the features of the symptoms and provide a basis for improving their quality of life.Methods A total of 342 breast cancer patients participated in the study. All patients had pathological diagnosis. They were investigated and evaluated from November 2020 to February 2021 with MDASI-C. The reliability and validity were evaluated respectively. Cluster analysis and correlation analysis were carried out.Results The Cronbach’s alpha coefficient of the symptom and interference items was 0.827 and 0.880, respectively, which meant good reliability. Construct validity revealed a four-factor structure. The Kaiser- Meyer-Olkin (KMO) value was 0.760, which meant good construct validity. The patient's KPS, treatment phase and cancer stage were grouped, and the differences of scores within the groups were significant. The patient's employment status, education level and age had a significant correlation with symptoms. The top three symptoms were disturbed sleep (3.10 ± 2.52), diffificulty remembering (2.54 ± 2.30) and fatigue (2.24 ± 2.13). The higher the patient's education, the lower their symptoms. Patients' Body Mass Index (BMI), hemoglobin (Hb), alkaline phosphatase (ALP), neutral granulocyte lymphocyte ratio (N/L), and serum albumin globulin ratio (A/G) also had an effect on some of the symptoms of patients. Conclusions MDASI-C is a reliable and effective assessment tool when evaluating patients with breast cancer of China. The symptoms were related to many clinical, biochemical indicators.


Sign in / Sign up

Export Citation Format

Share Document