Evaluation of VEP Parameters in Patients Before and After Cardiopulmonary By-Pass Surgery

Abstract Introduction: Coronary bypass surgery is emphasized in aetiology of ischemic optic neuropathy. Our aim in this study was to investigate the pattern visual evoked potentials (PVEP) in patients before and after coronary bypass surgery.Methods: Thirty-one patients were included in the study. After a full ophthalmological evaluation, PVEP was assesed in the pre and postoperative periods. Operative times, hematological parameters, blood pressures, number of transfusions, body temperatures, anaesthetic drugs and systemic illnesses were recorded for each patient. Results: The mean age of the patients were 59±10.4 years. There was 22 men and 9 women in the study. Only 3 of them needed transfusion during the surgery. The mean duration of the surgery was 3.2±0.7 hours. None of the patients had a history of visual disturbance or postoperative ischemic optic neuropathy. The mean VEP P100 amplitude was not statistically significantly different but the mean VEP P100 latency showed statistically significant difference between the preoperative and postoperative periods. (p=0.014) This significance was more appereant in patients with systemic illnesses. (p= 0.023) There was a positive correlation between the age and VEP P100 latency. (r = 0.402, p< 0.05) Conclusions: Although surgical techniques and equipments are developing each day in the field of cardiopulmonary bypass surgery, the contributing factors such as hypothermia, anemia and diabetes still seem to affect neurophysiological functions even after a noncomplicated surgery.

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Exercise Radionuclide Assessment of Left Ventricular Function Before and After Coronary Bypass Surgery

Angiology ◽

10.1177/000331978703800804 ◽

1987 ◽

Vol 38 (8) ◽

pp. 601-608 ◽

Cited By ~ 6

Author(s):

Ronald L. Lewis ◽

Jerry S. Videll ◽

Michael D. Strong ◽

Vladir Maranhao ◽

Frank J. Lumia

Keyword(s):

Left Ventricular Function ◽

Ventricular Function ◽

Bypass Surgery ◽

Coronary Bypass ◽

Left Ventricular ◽

Coronary Bypass Surgery ◽

Before And After

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The Psychodynamic Impact of Coronary Bypass Surgery

The International Journal of Psychiatry in Medicine ◽

10.2190/u8y8-gcng-m3xl-hvvy ◽

1981 ◽

Vol 10 (3) ◽

pp. 273-290 ◽

Cited By ~ 6

Author(s):

Shari Thurer ◽

Frederick Levine ◽

Robert Thurer

Keyword(s):

Physical Condition ◽

Bypass Surgery ◽

Coronary Bypass ◽

Psychological Evaluation ◽

Coronary Bypass Surgery ◽

Subjective Meaning ◽

Before And After ◽

Defensive Mechanisms

Twenty-one individuals underwent extensive psychological evaluation before, and four months after, coronary bypass surgery, that examined: defensive mechanisms; fantasies and distortions; subjective meaning of the procedure; and transference and projections. Patients showed a significant improvement in their physical condition and indicated vigorous psychodynamic activity. Both before and after surgery many patients: a) used denial; b) misconceived the procedure; c) developed a subjective explanation of etiology; d) mourned; and e) revered their surgeon. Following surgery, many patients: a) rationalized their decision; b) reviewed their life and changed priorities (valuing human closeness, devaluing work); and c) recognized their mortality (engendering a renewed interest in life and/or rage).

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Influence of a Concentrated Ethylester Compound of n-3 Fatty Acids on Lipids, Platelets and Coagulation in Patients Undergoing Coronary Bypass Surgery

Thrombosis and Haemostasis ◽

10.1055/s-0038-1646389 ◽

1991 ◽

Vol 66 (02) ◽

pp. 195-201 ◽

Cited By ~ 31

Author(s):

D W T Nilsen ◽

K Dalaker ◽

A Nordøy ◽

B Østerud ◽

O C Ingebretsen ◽

...

Keyword(s):

Fatty Acids ◽

Bypass Surgery ◽

Coronary Bypass ◽

Coronary Bypass Surgery ◽

Factor Vii ◽

Postoperative Phase ◽

Double Blind Study ◽

Strong Positive Correlation ◽

Significant Difference

SummaryTwenty patients accepted for coronary bypass surgery were randomized to receive either a concentrated ethylester compound of n-3 fatty acids, with a daily dose of 3.15 g of eicosapentaenoic acid (EPA) and 1.89 g of docosahexaenoic acid (DHA), or corn oil (controls) in a double blind study, to evaluate the effect on lipids, platelets and coagulation during the pre- and postoperative phase.Only patients with fasting triglyceride (TG) levels ≥1.6 mmol/1 at recruitment were eligible. The study was continued for 5 to 6 months. Surgery was usually performed at mid-intervention. Blood samples were collected during morning hours in fasting subjects, just prior to intervention, preoperatively and at final postoperative follow-up. Moreover, blood loss was accurately accounted for postoperatively.A threefold increase (p = 0.0001) of EPA was noted at pre-and postoperative follow-up. TG-levels were reduced 20 and 39%, respectively, in patients on n-3 fatty acids, reaching statistical significance at end of intervention (p = 0.034). TG-levels in controls remained largely unchanged. In patients on n-3 fatty acids, there was a statistically significant increase in serum total cholesterol preoperatively, but this change was no longer present at completion of the study.No significant changes were noted in platelet function, as judged by bleeding time, collagen induced platelet aggregation and release of TxB2 during aggregation. Parameters of extrinsic coagulation, including phospholipase C-sensitive factor VII (PLC-VII) and extrinsic pathway inhibitor (EPI), also remained essentially unchanged in both groups of patients. However, fibrinogen was significantly reduced in controls (p <0.05) at end of intervention. Moreover, a strong positive correlation was noted between PLC-VII and TG (r = 0.77, p = 0.0001).No significant difference in postoperative bleeding was noted between the two groups of patients.

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