scholarly journals Severe Neuroinflammatory Relapse After Extrauterine Pregnancy and Abortion: A Case Report on a Patient With Heterogenic Ms Phenotype Carrying Myelin Oligodendrocyte Glycoprotein Autoantibodies

Author(s):  
Katja Kulmala ◽  
Roosa Vaitiniemi ◽  
Helene Blad ◽  
Virginija Danylaite Karrenbauer

Abstract Background. Pregnancy has disease-modifying effects in MS. First trimester abortion might be followed by increased MS activity. MS with myelin oligodendrocyte glycoprotein (MOG) autoantibodies is a rare and agressive disease variant. Objectives. This case illustrates severe inflammatory reactivation after surgical abortion in MS patient who carries MOG antibodies. Methods. Case-report. Patient provided written informed consent for information and images to be published. Results. MRI and CSF biomarkers indicated high inflammatory activity post-abortion. Conclusions. Pregnancy termination in combination with MOG antibody carriership and termination of dimethyl fumarate treatment just prior abortion have had contributed to extensive reactivation of MS.

2021 ◽  
Author(s):  
Katja Selin ◽  
Roosa Vaitiniemi ◽  
Helene Blad ◽  
Virginija Danylaite Karrenbauer

Abstract Background. Pregnancy has disease-modifying effects in MS. First trimester abortion might be followed by increased MS activity. MS with myelin oligodendrocyte glycoprotein (MOG) autoantibodies is a rare and agressive disease variant.Objectives. This case illustrates severe inflammatory reactivation after surgical abortion in MS patient who carries MOG antibodies.Methods. Case-report. Patient provided written informed consent for information and images to be published. Results. MRI and CSF biomarkers indicated high inflammatory activity post-abortion. Conclusions. Pregnancy termination in combination with MOG antibody carriership and termination of dimethyl fumarate treatment just prior abortion have had contributed to extensive reactivation of MS.


2018 ◽  
Vol 4 (1) ◽  
pp. 1-5
Author(s):  
Bhaktabatsal Raut ◽  
Shreedhar Acharya

INTRODUCTION: This study was conducted to analyze the medical and surgical methods of first trimester of pregnancy. MATERIAL AND METHODS: A hospital based retrospective study done at Lumbini Zonal Hospital, Butwal over the period of one year, where all the women who had first trimester abortion services were analyzed. Age, parity, education status, failure rates and post abortion contraception were analyzed.RESULTS: There were total of 478 women who had abortion services, of which 244 women had medical method of abortion. Among them 4.89% were teenagers and 11.29% were primigravida and 6.9% were uneducated. The failure rate for medical method was 9% and for surgical method was 1.7%. Most women at their post abortion period asked for condoms, followed by DMPA, IUD and OCP as a method of contraception.CONCLUSION: Failure rate of medical method was high and acceptance of long acting post abortion contraception was low.Journal of Universal College of Medical Sciences (2016) Vol.04 No.01 Issue 13, page: 1-5


Contraception ◽  
2003 ◽  
Vol 67 (1) ◽  
pp. 49-51
Author(s):  
Alison Edelman ◽  
Jeffrey Jensen ◽  
Erica Nelson ◽  
Mark Nichols

Author(s):  
Kritika Tanwar ◽  
Bani Sarkar ◽  
Anjali Chauhan

Background: To study the Feto-maternal outcome in cases with previous surgical intervention for first trimester abortion on subsequent pregnancy and to compare with cases without history of previous abortion.Methods: A cross sectional observational study was conducted over a period of two years. Study included 80 consenting females at 28 weeks POG. Females with history of prior surgical abortion just before the present pregnancy were included as cases (n=40) and rest as controls (n=40). Detailed obstetric history was taken, subjects were then followed till delivery and feto-maternal outcomes such as period of gestation, mode of delivery birth weight, Apgar score, increased NICU stay at the time of delivery were recorded and analyzed.Results: We observed that the women with history of induced surgical abortion were at increased risk of Pre term birth (52.5%, p value0.006), Cesarean section (40%, p value 0.012), Low birth weight (47.5%, p value <0.001), increased NICU stay (32.5%, p value 0.027) compared to primi-gravida controls.Conclusions: We concluded that women with previous history of induced surgical abortions were at increased risk of preterm birth, very preterm birth and low birth weight babies, NICU stay in the subsequent pregnancies. The risk of caesarean was found to be increased in women with previous induced abortions exposing the women to the morbidity associated with the C-section. Hence patient with prior history of surgical first trimester abortion needs more vigilant monitoring during antenatal period in subsequent pregnancy.


Author(s):  
Suryaprakash Jagdevappa Karande ◽  
Meena Shantanu Gunjotikar

Background: The methods of terminating pregnancy in the first trimester are simple, safe and effective. Factors like lack of knowledge about availability of MTP services, ignorance, denial of pregnancy, fear of society may account for decrease in number of first trimester abortions. The aims of the present study were to compare the efficacy, induction abortion interval and side effects of intravaginal misoprostol with extra amniotic installation of ethacridine lactate for second trimester abortion.Methods: 60 women coming to MTP clinics requesting second trimester pregnancy termination between 12 to 20 weeks were selected. Detail history and examination was carried out in each patient. They divided into two groups, Group A (30) intravaginal misoprostol 400 initially followed by 400 micrograns every 6 hourly if required. Group B (30) extra-amniotic 0.1% ethacridine lactate 150 cc.Results: In Group A success rate was 100% while in Group B it was 76.66%, which is highly statistically significant (P< 0.01). Mean I – A interval in Group A was 14.58+5.25 hours was highly significantly less than in Group B, it was 33.91 + 3.97 hours (p<0.0001). In Group A complete abortion has occurred in 28 cases (93.33%) and in Group B in 12 cases (52.17%).Conclusions: We conclude that, as compared to extra-amniotic instillation of ethacridinelactate intravaginal misoprostol is the preferred regimen in second trimester abortion because of its high efficacy, shorter induction abortion interval, high incidence of completeness of abortion, low incidence of side effects and better tolerance by the patient. 


Sexual Health ◽  
2018 ◽  
Vol 15 (5) ◽  
pp. 477
Author(s):  
Paris Stowers ◽  
Aneesa Thannickal ◽  
Martha Wojtowycz ◽  
Jodi Wallis ◽  
Zevidah V. Reiss

Anaesthesiologists are vital to abortion access in the US. An online survey of 215 anaesthesiology residents assessed attitudes towards abortion. Among the surveyed residents, first-trimester abortion was more acceptable than second-trimester abortion (P < 0.001). Few respondents objected to abortion in cases of fetal anomalies or maternal health indications. Further, 77.3% of surveyed residents reported past participation in abortion procedures, including 77.8% of residents with objections to abortion in some circumstances. Anaesthesiology residents who are female, childless and non-religious were more likely to find first-trimester abortion acceptable.


2013 ◽  
Vol 8 (1) ◽  
pp. 14-17
Author(s):  
Ashis Shrestha ◽  
P Sharma

Aims: This study was conducted to find out choice and acceptance of contraceptives in clients coming for first trimester abortion. Methods: This was a cross sectional descriptive study carried out from the records of clients who received comprehensive abortion care service in first trimester at Kasthamandap health care centre from June 2008 to June 2010. Results: Total 707 clients came for abortion who fulfilled inclusion criteria. Contraceptive acceptance was 49.5%. Most frequently used contraceptives were injectable (depot medroxyprogesterone) 22.8%, oral contraceptive pills 19.6%, condom 6.1%, intra-uterine contraceptive device 0.8% and norplant 0.3%. Conclusions: This study showed a low acceptance rate of contraception. This suggests the need for reviewing the policy of post abortion contraception. The study also highlighted that depot provera was the most accepted contraception. Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 1 / Issue 15 / Jan- June, 2013 / 14-17 DOI: http://dx.doi.org/10.3126/njog.v8i1.8854


2014 ◽  
Vol 6 (1) ◽  
pp. 33-34
Author(s):  
Reeti Mehra ◽  
Dilpreet Kaur Pandhar ◽  
Anju Huria

ABSTRACT Dilatation and evacuation (D and E) is the most commonly used method for later abortion. It is one of the safest procedure when performed by experienced personnel. Complication rates are high in second trimester abortion compared to first trimester. Rupture of uterine wall covered with organized blood clots is very rare complication after second trimester surgical abortion. It is a surgical emergency and may have deleterious consequences if diagnosis is delayed. How to cite this article Kaur M, Pandhar DK, Mehra R, Huria A. A Complication of Surgical Abortion: A Rare Presentation. J South Asian Feder Obst Gynae 2014;6(1):33-34.


2003 ◽  
Vol 33 (1) ◽  
pp. 28-38 ◽  
Author(s):  
Sheila Faure ◽  
Helene Loxton

This study examined the relationship between anxiety, depression, perceived self-efficacy and biographical variables, before and after the termination of a first trimester pregnancy. Seventy-six participants were recruited from three health facilities in the Western Cape, South Africa. Scores on the State-Trait Anxiety Scale, the Beck Depression Inventory and a Self-Efficacy Scale revealed that high levels of state-anxiety and moderate levels of depression were experienced before abortion. Levels of anxiety and depression generally decreased significantly within a three-week period after the abortion. High self-efficacy was related to lowerlevels of anxiety and depression. Higher levels of education and self-efficacy and low levels of depression, trait-anxiety and gestational age were significantly related to healthy short-term adjustment. It was shown that pre-abortion depression and self-efficacy scores had the power to predict post-abortion depression.


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