scholarly journals Mycofabrication of Silver Oxide Nanoparticles Derived from Aspergillus Terreus FC36AY1 and its Potent Antimicrobial, Antioxidant, and Anti-Angiogenesis Activities

Author(s):  
Manon Mani Vellingiri ◽  
Mithu Ashwin John Kennedy ◽  
Parimala Gnana Soundari Arockiam Jeyasundar ◽  
Swamiappan Sathiskumar ◽  
Ulaganathan Priyadharshini ◽  
...  

Abstract The present study focused to synthesize the silver oxide nanoparticles (AgONPs) from endophytic fungus, as the strain eventually possess the medicinal property acquired from the medicinal tree, Aegle marmelos. About 35 pigmented endophytic fungi were isolated, screened for antagonistic activity against 12 clinical human pathogens and antioxidant activity through DPPH radical scavenging assay; among the isolates, FC36AY1 explored the highest activity. The endophytic fungus was identified as Aspergillus terreus FC36AY1 through microscopic and Internal Transcribed Spacer (ITS) 1, ITS 4 and 18S rRNA amplification. The AgONPs were synthesized from the strain FC36AY1 and characterized for its confirmation, functional groups, nanostructures with unit cell dimensions, size and shape, presence of elements through UV-Vis spectrophotometry, FT-IR, X-Ray Diffraction, Scanning Electron Microscopic with EDX analysis. The myco-generated AgONPs manifested their antimicrobial and antioxidant properties with maximum activity at minimum concentration. Moreover, the inhibition of angiogenesis by the AgONPs in Hen’s Egg Test on the Chorio-Allantoic Membrane analysis evinced significant bioactivity at least concentration. Thus the results of this investigation revealed that this bioactive fungal mediated AgONPs can be exploited as potential in biomedical applications.

2017 ◽  
Vol 26 (4) ◽  
pp. 1025-1035 ◽  
Author(s):  
Neveen A. Salem ◽  
Mohammed A. Wahba ◽  
Wael H. Eisa ◽  
Marwa El-Shamarka ◽  
Wagdy Khalil

Biomaterials ◽  
2014 ◽  
Vol 35 (13) ◽  
pp. 4223-4235 ◽  
Author(s):  
Ang Gao ◽  
Ruiqiang Hang ◽  
Xiaobo Huang ◽  
Lingzhou Zhao ◽  
Xiangyu Zhang ◽  
...  

Materials ◽  
2020 ◽  
Vol 13 (9) ◽  
pp. 2009 ◽  
Author(s):  
Łukasz Laskowski ◽  
Anna Majtyka-Piłat ◽  
Krzysztof Cpałka ◽  
Maciej Zubko ◽  
Magdalena Laskowska

The synthesis routes are presented for the preparation of nanocomposites composed of nanocrystals placed inside SBA-15 silica pores. The procedures assume treating the silica channels as nanoreactors, where nanocrystals are created as a result of thermal decomposition of internal functional units. Its sizes and chemical composition can be modified by the change of functional group types and density inside silica channels. The procedure is demonstrated by the example of copper pyrophosphate quantum dots and silver oxide nanoparticles inside silica mezochannels. The method can be easily adopted to other types of nanocrystals that can be synthesized inside silica nanoreactors.


RSC Advances ◽  
2013 ◽  
Vol 3 (6) ◽  
pp. 1732-1734 ◽  
Author(s):  
Xin Zhou ◽  
Yi Lu ◽  
Ling-Ling Zhai ◽  
Yue Zhao ◽  
Qing Liu ◽  
...  

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