scholarly journals Urinary Metabolomics Revealed the Biological Characteristics Associated with Early Pregnancy in Pigs

2021 ◽  
Author(s):  
Chen Zhou ◽  
Gengyuan Cai ◽  
Fanming Meng ◽  
Qun Hu ◽  
Guohao Liang ◽  
...  
Keyword(s):  
Early Pregnancy ◽  
High Performance ◽  
Ultrasound Examination ◽  
Urinary Metabolites ◽  
Metabolic Changes ◽  
Liquid Chromatography Mass Spectrometry ◽  
High Confidence ◽  
Pregnancy Status ◽  
Estrus Phase ◽  
In Pregnancy

Abstract Background Accurate early detection of pregnancy status is a prerequisite for effective monitoring of fertility in pig. In the early phase of pregnancy, because the embryo is small and in a free state, it is difficult to determine whether it is pregnant based on B-ultrasound examination. This calls for development of novel tools to accurately diagnose early pregnancy. Metabolomics reveal the metabolic status of cells, tissues and organisms. Results In this study, we investigated urinary metabolites in sows during early pregnancy. A total of 32 samples from 8 sows were collected at estrus and each phase of early pregnancy (days 9, 12, and 15 of gestation). Metabolites in urine samples from different sows obtained from gestation and estrus phases were analyzed via ultra-high performance liquid chromatography/mass spectrometry. A total of 530 metabolites were identified with high confidence in all samples. Compared with samples collected during the estrus phase, 269 differential metabolites were found in samples obtained during early pregnancy. Conclusions These metabolites included lipids and lipid-like molecules, organic acids and their derivatives, organic oxygen compounds, organoheterocyclic compounds, benzenoids, among others. These metabolites, such as choline and pregnanediol-3-glucuronide, play a very important role in pregnancy. They also regulate pregnancy in other animals. Our results provide novel insights into the metabolic changes in the urine of sows in the early pregnancy phase. The level of different metabolites in urine can be used to diagnosis pregnancy in sows. Understanding these metabolic changes is helpful for better management of pregnant sows.

Pregnancy changes and early pregnancy complications

2016 ◽  
Author(s):  
Stergios K. Doumouchtsis ◽  
S. Arulkumaran ◽  
S. Arulkumaran ◽  
Edwin Chandraharan ◽  
Christina Coroyannakis ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Early Pregnancy ◽  
Pregnancy Complications ◽  
Gestational Trophoblastic Disease ◽  
Metabolic Changes ◽  
Physiological Changes ◽  
Trophoblastic Disease ◽  
Changes In Pregnancy ◽  
Physiological Changes In Pregnancy ◽  
In Pregnancy

This chapter discusses pregnancy changes and early pregnancy complications. It includes physiological changes in pregnancy (cardiovascular, haematological, respiratory, renal and urinary tract, and metabolic changes), gestational trophoblastic disease (GTD), and nausea and vomiting.

scholarly journals Combination of Sulfuric Acid (H2SO4) and Aquadest to Detect Goat Pregnancy

2018 ◽  
Vol 3 (2) ◽  
pp. 62-66
Author(s):  
Nur Ifa Rohmayanti ◽  
Ayu Wulandari ◽  
Muhammad Rifai ◽  
H. Hastuti
Keyword(s):  
Sulfuric Acid ◽  
Early Pregnancy ◽  
Detection Method ◽  
Production Time ◽  
Traditional Methods ◽  
Breeding Programs ◽  
Livestock Management ◽  
Pregnancy Status ◽  
Reducing Costs ◽  
In Pregnancy

Pregnancy detection is an essential thing to do after cattle are mated. In general, early pregnancy detection is needed regarding identifying animals that are not pregnant immediately after natural mate or artificial mate, so that production time is lost because infertility can be suppressed by proper handling such as livestock must be sold or dialing (cut). It is aimed at reducing costs for breeding, programs and helping livestock management economically. Many methods can be used for pregnancy detection depending on the species, age of pregnancy, cost, accuracy, and speed of diagnosis. The purpose of each method used in pregnancy examinations is to determine the pregnancy status with 100% accuracy, especially in the Watubangga and Toari areas, which breeders are still applying traditional methods, which this detection method can reduce costs, time and effort, especially this detection method relatively cheap and easy to do.

“The black box” of nonviable pregnancy in early gestation

2017 ◽  
Author(s):  
Å.S. Emelyanenko , A.Yu. Blinov , T.M. Volkovskaya
Keyword(s):  
Early Pregnancy ◽  
Ultrasound Examination ◽  
Black Box ◽  
Safety Regulation ◽  
Intrauterine Pregnancy ◽  
Early Gestation ◽  
Prognostic Criteria

The modern sonographic approach to define miscarriage in early pregnancy was shown in the article. Ultrasound diagnostic and prognostic criteria of nonviable pregnancy in early gestation were introduced. Special attention was paid to the examination`s algorithm and repeatability of ultrasound scans with suspicion of intrauterine pregnancy of uncertain viability. Also the consequences of non-following the stringent ultrasound criteria, which lead to the abortions of potentially normal pregnancies were described. Furthermore, the authors highlighted the importance of safety regulation`s aspects in ultrasound examination in early gestation. The conclusion of the importance and need in following the uniform methodological criteria in diagnostics of nonviable pregnancy has been drawn according to the analysis of world experience.

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