scholarly journals Rapid Deployment and Application Exploration of the Mobile Shelter Laboratories Under T He Outbreak of COVID-19 Epidemic

2021 ◽  
Author(s):  
Yi Luan ◽  
Rui Ding ◽  
Wenshen Gu ◽  
Xiaofan Zhang ◽  
Xinliang Chen ◽  
...  
Keyword(s):  
Large Scale ◽  
Mainland China ◽  
Reference Value ◽  
Guangdong Province ◽  
Real Data ◽  
Practical Experience ◽  
Rapid Expansion ◽  
Nucleic Acid Detection ◽  
Short Period ◽  
Detection Capabilities

Abstract Since the end of 2019, the COVID-19 epidemic has swept the world. With the widespread spread of the COVID-19 and the continuous emergence of mutated strains, the situation for the prevention and control of the COVID-19 epidemic remains severe. On May 21, 2021, Guangzhou City, Guangdong Province, notified the discovery of a new locally confirmed case. Guangzhou became the first city in mainland China to compete with the delta mutant strain. As a local hospital with strong nucleic acid detection capabilities, Sun Yat-sen University Sun Yat-sen Memorial Hospital took the lead in launching the construction and deployment of the Mobile Shelter Laboratories and large-scale screening work in Foshan and Zhanjiang, Guangdong Province. Through summarizing "practical" experience, observation and comparison data analysis, we use real data to verify a feasible solution for rapid expansion of detection capabilities in a short period of time. We hope that these experiences will have certain reference value for other countries or regions, especially the underdeveloped areas of medical and health care.

Some comments about observations and image processing of comet 29P/Schwassmann-Wachmann 1

1999 ◽  
Vol 173 ◽  
pp. 243-248
Author(s):  
D. Kubáček ◽  
A. Galád ◽  
A. Pravda
Keyword(s):  
Image Processing ◽  
Large Scale ◽  
Harvard College ◽  
Oak Ridge ◽  
Large Scale Structures ◽  
Short Period Comet ◽  
Short Period ◽  
Scale Structures ◽  
Harvard College Observatory ◽  
Period Comet

AbstractUnusual short-period comet 29P/Schwassmann-Wachmann 1 inspired many observers to explain its unpredictable outbursts. In this paper large scale structures and features from the inner part of the coma in time periods around outbursts are studied. CCD images were taken at Whipple Observatory, Mt. Hopkins, in 1989 and at Astronomical Observatory, Modra, from 1995 to 1998. Photographic plates of the comet were taken at Harvard College Observatory, Oak Ridge, from 1974 to 1982. The latter were digitized at first to apply the same techniques of image processing for optimizing the visibility of features in the coma during outbursts. Outbursts and coma structures show various shapes.

The Introduction of Plantations into East Sumatra and its Socio-economic Impacts, 1863-1929

2020 ◽  
Vol 6 (5) ◽  
pp. 563-576
Keyword(s):  
Twentieth Century ◽  
Social Transformation ◽  
Rapid Expansion ◽  
Local Resistance ◽  
Short Period ◽  
Late Nineteenth ◽  
Fierce Competition ◽  
Plantation Crops ◽  
Colonial Government ◽  
Economic Regions

The goal of this article is to examine the introduction of plantations into East Sumatra (Indonesia) in the late nineteenth and early twentieth century. Attention is given to the five most important plantation crops, namely tobacco, rubber, oil palm, tea, and fiber. The article analyzes the economic and social transformation of the region as a consequence of the rapid expansion of plantations. Within a short period of time, East Sumatra emerged to become one of the most dynamic economic regions of Southeast Asia. The development of the region and the needs of a source of protection for Dutch planters in face of fierce competition from other Western companies and local resistance encouraged the Dutch colonial government to establish effective authority in East Sumatra. Received 4th June 2020; Revised 15th September 2020; Accepted 26th September 2020

scholarly journals Rapid, large-scale species discovery in hyperdiverse taxa using 1D MinION sequencing

BMC Biology ◽  
2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Amrita Srivathsan ◽  
Emily Hartop ◽  
Jayanthi Puniamoorthy ◽  
Wan Ting Lee ◽  
Sujatha Narayanan Kutty ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Large Scale ◽  
Low Cost ◽  
Small Body ◽  
Small Subset ◽  
Similar Species ◽  
Large Species ◽  
Morphological Examination ◽  
Species Discovery ◽  
Short Period

Abstract Background More than 80% of all animal species remain unknown to science. Most of these species live in the tropics and belong to animal taxa that combine small body size with high specimen abundance and large species richness. For such clades, using morphology for species discovery is slow because large numbers of specimens must be sorted based on detailed microscopic investigations. Fortunately, species discovery could be greatly accelerated if DNA sequences could be used for sorting specimens to species. Morphological verification of such “molecular operational taxonomic units” (mOTUs) could then be based on dissection of a small subset of specimens. However, this approach requires cost-effective and low-tech DNA barcoding techniques because well-equipped, well-funded molecular laboratories are not readily available in many biodiverse countries. Results We here document how MinION sequencing can be used for large-scale species discovery in a specimen- and species-rich taxon like the hyperdiverse fly family Phoridae (Diptera). We sequenced 7059 specimens collected in a single Malaise trap in Kibale National Park, Uganda, over the short period of 8 weeks. We discovered > 650 species which exceeds the number of phorid species currently described for the entire Afrotropical region. The barcodes were obtained using an improved low-cost MinION pipeline that increased the barcoding capacity sevenfold from 500 to 3500 barcodes per flowcell. This was achieved by adopting 1D sequencing, resequencing weak amplicons on a used flowcell, and improving demultiplexing. Comparison with Illumina data revealed that the MinION barcodes were very accurate (99.99% accuracy, 0.46% Ns) and thus yielded very similar species units (match ratio 0.991). Morphological examination of 100 mOTUs also confirmed good congruence with morphology (93% of mOTUs; > 99% of specimens) and revealed that 90% of the putative species belong to the neglected, megadiverse genus Megaselia. We demonstrate for one Megaselia species how the molecular data can guide the description of a new species (Megaselia sepsioides sp. nov.). Conclusions We document that one field site in Africa can be home to an estimated 1000 species of phorids and speculate that the Afrotropical diversity could exceed 200,000 species. We furthermore conclude that low-cost MinION sequencers are very suitable for reliable, rapid, and large-scale species discovery in hyperdiverse taxa. MinION sequencing could quickly reveal the extent of the unknown diversity and is especially suitable for biodiverse countries with limited access to capital-intensive sequencing facilities.

scholarly journals LARGE SCALE CITY MAPPING USING SATELLITE IMAGERY / KOSMINIŲ NUOTRAUKŲ IŠ GOOGLE EARTH, TAIKOMŲ MIESTAMS KARTOGRAFUOTI STAMBIUOJU MASTELIU, REKTIFIKAVIMAS / РЕКТИФИКАЦИЯ КОСМИЧЕСКИХ СНИМКОВ ИЗ GOOGLE EARTH ДЛЯ КРУПНОМАСШТАБНОГО КАРТОГРАФИРОВАНИЯ ГОРОДОВ

2012 ◽  
Vol 37 (4) ◽  
pp. 168-171 ◽  
Author(s):  
Birutė Ruzgienė ◽  
Qian Yi Xiang ◽  
Silvija Gečytė
Keyword(s):  
Satellite Imagery ◽  
Large Scale ◽  
Modern Technology ◽  
Google Earth ◽  
Aerial Images ◽  
Control Points ◽  
Image Rectification ◽  
Image Deformation ◽  
Map Construction ◽  
Short Period

The rectification of high resolution digital aerial images or satellite imagery employed for large scale city mapping is modern technology that needs well distributed and accurately defined control points. Digital satellite imagery, obtained using widely known software Google Earth, can be applied for accurate city map construction. The method of five control points is suggested for imagery rectification introducing the algorithm offered by Prof. Ruan Wei (tong ji University, Shanghai). Image rectification software created on the basis of the above suggested algorithm can correct image deformation with required accuracy, is reliable and keeps advantages in flexibility. Experimental research on testing the applied technology has been executed using GeoEye imagery with Google Earth builder over the city of Vilnius. Orthophoto maps at the scales of 1:1000 and 1:500 are generated referring to the methodology of five control points. Reference data and rectification results are checked comparing with those received from processing digital aerial images using a digital photogrammetry approach. The image rectification process applying the investigated method takes a short period of time (about 4-5 minutes) and uses only five control points. The accuracy of the created models satisfies requirements for large scale mapping. Santrauka Didelės skiriamosios gebos skaitmeninių nuotraukų ir kosminių nuotraukų rektifikavimas miestams kartografuoti stambiuoju masteliu yra nauja technologija. Tai atliekant būtini tikslūs ir aiškiai matomi kontroliniai taškai. Skaitmeninės kosminės nuotraukos, gautos taikant plačiai žinomą programinį paketą Google Earth, gali būti naudojamos miestams kartografuoti dideliu tikslumu. Siūloma nuotraukas rektifikuoti Penkių kontrolinių taskų metodu pagal prof. Ruan Wei (Tong Ji universitetas, Šanchajus) algoritmą. Moksliniam eksperimentui pasirinkta Vilniaus GeoEye nuotrauka iš Google Earth. 1:1000 ir 1:500 mastelio ortofotografiniai žemėlapiai sudaromi Penkių kontrolinių taškų metodu. Rektifikavimo duomenys lyginami su skaitmeninių nuotraukų apdorojimo rezultatais, gautais skaitmeninės fotogrametrijos metodu. Nuotraukų rektifikavimas Penkių kontrolinių taskų metodu atitinka kartografavimo stambiuoju masteliu reikalavimus, sumažėja laiko sąnaudos. Резюме Ректификация цифровых и космических снимков высокой резолюции для крупномасштабного картографирования является новой технологией, требующей точных и четких контрольных точек. Цифровые космические снимки, полученные с использованием широкоизвестного программного пакета Google Earth, могут применяться для точного картографирования городов. Для ректификации снимков предложен метод пяти контрольных точек с применением алгоритма проф. Ruan Wei (Университет Tong Ji, Шанхай). Для научного эксперимента использован снимок города Вильнюса GeoEye из Google Earth. Ортофотографические карты в масштабе 1:1000 и 1:500 генерируются с применением метода пяти контрольных точек. Полученные результаты и данные ректификации сравниваются с результатами цифровых снимков, полученных с применением метода цифровой фотограмметрии. Ректификация снимков с применением метода пяти контрольных точек уменьшает временные расходы и удовлетворяет требования, предъявляемые к крупномасштабному картографированию.

scholarly journals Heterogeneity and effectiveness analysis of COVID-19 prevention and control in major cities in China through time-varying reproduction number estimation

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Qing Cheng ◽  
Zeyi Liu ◽  
Guangquan Cheng ◽  
Jincai Huang
Keyword(s):  
Prevention And Control ◽  
Large Scale ◽  
Reproduction Number ◽  
Correlation Method ◽  
Control Measures ◽  
Time Varying ◽  
Short Period ◽  
Significant Difference ◽  
Prevention And Control Measures ◽  
And Control

AbstractBeginning on December 31, 2019, the large-scale novel coronavirus disease 2019 (COVID-19) emerged in China. Tracking and analysing the heterogeneity and effectiveness of cities’ prevention and control of the COVID-19 epidemic is essential to design and adjust epidemic prevention and control measures. The number of newly confirmed cases in 25 of China’s most-affected cities for the COVID-19 epidemic from January 11 to February 10 was collected. The heterogeneity and effectiveness of these 25 cities’ prevention and control measures for COVID-19 were analysed by using an estimated time-varying reproduction number method and a serial correlation method. The results showed that the effective reproduction number (R) in 25 cities showed a downward trend overall, but there was a significant difference in the R change trends among cities, indicating that there was heterogeneity in the spread and control of COVID-19 in cities. Moreover, the COVID-19 control in 21 of 25 cities was effective, and the risk of infection decreased because their R had dropped below 1 by February 10, 2020. In contrast, the cities of Wuhan, Tianmen, Ezhou and Enshi still had difficulty effectively controlling the COVID-19 epidemic in a short period of time because their R was greater than 1.

scholarly journals Constructing Large-Scale Genetic Maps Using an Evolutionary Strategy Algorithm

Genetics ◽  
2003 ◽  
Vol 165 (4) ◽  
pp. 2269-2282
Author(s):  
D Mester ◽  
Y Ronin ◽  
D Minkov ◽  
E Nevo ◽  
A Korol
Keyword(s):  
Discrete Optimization ◽  
High Performance ◽  
Large Scale ◽  
Simulated Data ◽  
Real Data ◽  
Genetic Maps ◽  
Chromosome 1 ◽  
Evolutionary Strategy ◽  
Group A ◽  
The One

Abstract This article is devoted to the problem of ordering in linkage groups with many dozens or even hundreds of markers. The ordering problem belongs to the field of discrete optimization on a set of all possible orders, amounting to n!/2 for n loci; hence it is considered an NP-hard problem. Several authors attempted to employ the methods developed in the well-known traveling salesman problem (TSP) for multilocus ordering, using the assumption that for a set of linked loci the true order will be the one that minimizes the total length of the linkage group. A novel, fast, and reliable algorithm developed for the TSP and based on evolution-strategy discrete optimization was applied in this study for multilocus ordering on the basis of pairwise recombination frequencies. The quality of derived maps under various complications (dominant vs. codominant markers, marker misclassification, negative and positive interference, and missing data) was analyzed using simulated data with ∼50-400 markers. High performance of the employed algorithm allows systematic treatment of the problem of verification of the obtained multilocus orders on the basis of computing-intensive bootstrap and/or jackknife approaches for detecting and removing questionable marker scores, thereby stabilizing the resulting maps. Parallel calculation technology can easily be adopted for further acceleration of the proposed algorithm. Real data analysis (on maize chromosome 1 with 230 markers) is provided to illustrate the proposed methodology.

scholarly journals Meta-Descent for Online, Continual Prediction

2019 ◽  
Vol 33 ◽  
pp. 3943-3950
Author(s):  
Andrew Jacobsen ◽  
Matthew Schlegel ◽  
Cameron Linke ◽  
Thomas Degris ◽  
Adam White ◽  
...  
Keyword(s):  
Gradient Descent ◽  
Large Scale ◽  
Time Series Prediction ◽  
Real Data ◽  
Second Order ◽  
Stochastic Gradient Descent ◽  
Step Size ◽  
Vector Approximation ◽  
Prediction Problems ◽  
Stationary Problems

This paper investigates different vector step-size adaptation approaches for non-stationary online, continual prediction problems. Vanilla stochastic gradient descent can be considerably improved by scaling the update with a vector of appropriately chosen step-sizes. Many methods, including AdaGrad, RMSProp, and AMSGrad, keep statistics about the learning process to approximate a second order update—a vector approximation of the inverse Hessian. Another family of approaches use meta-gradient descent to adapt the stepsize parameters to minimize prediction error. These metadescent strategies are promising for non-stationary problems, but have not been as extensively explored as quasi-second order methods. We first derive a general, incremental metadescent algorithm, called AdaGain, designed to be applicable to a much broader range of algorithms, including those with semi-gradient updates or even those with accelerations, such as RMSProp. We provide an empirical comparison of methods from both families. We conclude that methods from both families can perform well, but in non-stationary prediction problems the meta-descent methods exhibit advantages. Our method is particularly robust across several prediction problems, and is competitive with the state-of-the-art method on a large-scale, time-series prediction problem on real data from a mobile robot.

scholarly journals ALVIC versus the Internet: Redesigning a Networked Virtual Environment Architecture

2008 ◽  
Vol 2008 ◽  
pp. 1-9 ◽  
Author(s):  
Peter Quax ◽  
Jeroen Dierckx ◽  
Bart Cornelissen ◽  
Wim Lamotte
Keyword(s):  
Virtual Environment ◽  
Large Scale ◽  
Virtual Communities ◽  
Real Life ◽  
Point Of View ◽  
The Internet ◽  
Generic Framework ◽  
Short Period ◽  
Networked Virtual Environment ◽  
Near Future

The explosive growth of the number of applications based on networked virtual environment technology, both games and virtual communities, shows that these types of applications have become commonplace in a short period of time. However, from a research point of view, the inherent weaknesses in their architectures are quickly exposed. The Architecture for Large-Scale Virtual Interactive Communities (ALVICs) was originally developed to serve as a generic framework to deploy networked virtual environment applications on the Internet. While it has been shown to effectively scale to the numbers originally put forward, our findings have shown that, on a real-life network, such as the Internet, several drawbacks will not be overcome in the near future. It is, therefore, that we have recently started with the development of ALVIC-NG, which, while incorporating the findings from our previous research, makes several improvements on the original version, making it suitable for deployment on the Internet as it exists today.

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