Impact of the Gamma Variant on the ICU Admission in a Hospital of the Autonomous City of Buenos Aires (Caba), Argentina

Abstract Purpose: Comparison between patients admitted to the Intensive Care Unit (ICU) with ventilatory support during the first and second wave (Gamma variant) of COVID 19 in a tertiary hospital in the City of Buenos Aires.Method: Descriptive, observational, prospective cohort study in ICU of an acute general hospital in Argentina, with patients adult patients COVID-19 admitted consecutively to the ICU. The ICU the main variables of interest: Demographic and laboratory data, history, duration of MV, mortality.Results: 44 patients were recruited during the first wave, and 80 in the second. Significant differences were observed in the second wave for age (60, [SD 11]; vs 68 [SD 11]; p <0.01), days with symptoms (9 [SD 5]; vs 4.5 [SD 3]; p <0.01), duration of MV (10 days [SD 7]; vs 16 [SD 13]; p <0.01), Ferritin (1450 mcg / l [SD 547]; vs 941 mcg / l [ SD 593]; p 0.04) and use of antibiotics (97% vs 45% p <0.01). There was no difference in mortality (66% vs 78% p 0.14) but there was in its primary causes; being more frequent hypoxemia associated with sepsis in the second wave (40% vs 3.4% p <0.01) and hypoxemia and multiorgan failure in the first (28% vs 4% p <0.01).Conclusions: During the second wave of the pandemic, due to Gamma variant, more patients were admitted to our unit, younger, with a longer evolution time, a shorter time on MV and a greater inflammatory response, with no difference in mortality, although there was a difference in its causes.

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Impact of the Gamma Variant on the ICU Admission in a Hospital of the Autonomous City of Buenos Aires (CABA), Argentina

10.21203/rs.3.rs-997171/v4 ◽

2021 ◽

Author(s):

Veronica Mandich ◽

Daniel Chiacchiara ◽

Marcelo Bravo ◽

Antonio Pilipec ◽

Santiago Grimaldi ◽

...

Keyword(s):

Intensive Care Unit ◽

Buenos Aires ◽

Multiorgan Failure ◽

Laboratory Data ◽

Ventilatory Support ◽

Tertiary Hospital ◽

Observational Prospective Cohort Study ◽

Data History ◽

The City ◽

Second Wave

Abstract Purpose: Comparison between patients admitted to the Intensive Care Unit (ICU) with ventilatory support during the first and second wave (Gamma variant) of COVID 19 in a tertiary hospital in the City of Buenos Aires.Method: Descriptive, observational, prospective cohort study in ICU of an acute general hospital in Argentina, with patients adult patients COVID-19 admitted consecutively to the ICU. The ICU the main variables of interest: Demographic and laboratory data, history, duration of MV, mortality.Results: 44 patients were recruited during the first wave, and 80 in the second. Significant differences were observed in the second wave for age (60, [SD 11]; vs 68 [SD 11]; p <0.01), days with symptoms (9 [SD 5]; vs 4.5 [SD 3]; p <0.01), duration of MV (10 days [SD 7]; vs 16 [SD 13]; p <0.01), Ferritin (1450 mcg / l [SD 547]; vs 941 mcg / l [ SD 593]; p 0.04) and use of antibiotics (97% vs 45% p <0.01). There was no difference in mortality (66% vs 78% p 0.14) but there was in its primary causes; being more frequent hypoxemia associated with sepsis in the second wave (40% vs 3.4% p <0.01) and hypoxemia and multiorgan failure in the first (28% vs 4% p <0.01).Conclusions: During the second wave of the pandemic, due to Gamma variant, more patients were admitted to our unit, younger, with a longer evolution time, a shorter time on MV and a greater inflammatory response, with no difference in mortality, although there was a difference in its causes.

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Impact of the Gamma Variant on the ICU Admission in a Hospital of the Autonomous City of Buenos Aires (CABA), Argentina

10.21203/rs.3.rs-997171/v3 ◽

2021 ◽

Author(s):

Veronica Mandich ◽

Daniel Chiacchiara ◽

Marcelo Bravo ◽

Antonio Pilipec ◽

Santiago Grimaldi ◽

...

Keyword(s):

Intensive Care Unit ◽

Buenos Aires ◽

Multiorgan Failure ◽

Laboratory Data ◽

Ventilatory Support ◽

Tertiary Hospital ◽

Observational Prospective Cohort Study ◽

Data History ◽

The City ◽

Second Wave

Abstract Purpose: Comparison between patients admitted to the Intensive Care Unit (ICU) with ventilatory support during the first and second wave (Gamma variant) of COVID 19 in a tertiary hospital in the City of Buenos Aires.Method: Descriptive, observational, prospective cohort study in ICU of an acute general hospital in Argentina, with patients adult patients COVID-19 admitted consecutively to the ICU. The ICU the main variables of interest: Demographic and laboratory data, history, duration of MV, mortality.Results: 44 patients were recruited during the first wave, and 80 in the second. Significant differences were observed in the second wave for age (60, [SD 11]; vs 68 [SD 11]; p <0.01), days with symptoms (9 [SD 5]; vs 4.5 [SD 3]; p <0.01), duration of MV (10 days [SD 7]; vs 16 [SD 13]; p <0.01), Ferritin (1450 mcg / l [SD 547]; vs 941 mcg / l [ SD 593]; p 0.04) and use of antibiotics (97% vs 45% p <0.01). There was no difference in mortality (66% vs 78% p 0.14) but there was in its primary causes; being more frequent hypoxemia associated with sepsis in the second wave (40% vs 3.4% p <0.01) and hypoxemia and multiorgan failure in the first (28% vs 4% p <0.01).Conclusions: During the second wave of the pandemic, due to Gamma variant, more patients were admitted to our unit, younger, with a longer evolution time, a shorter time on MV and a greater inflammatory response, with no difference in mortality, although there was a difference in its causes.

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Impact of the gamma variant on the icu admission in a hospital of the autonomous city of Buenos Aires (Caba), Argentina

Global Journal of Infectious Diseases and Clinical Research ◽

10.17352/2455-5363.000048 ◽

2021 ◽

pp. 058-063

Author(s):

Mandich Verónica ◽

Chiacchiara Daniel ◽

Pilipec Antonio ◽

Grimaldi Santiago ◽

Cotez Johnny ◽

...

Keyword(s):

Buenos Aires ◽

Multiorgan Failure ◽

Laboratory Data ◽

Ventilatory Support ◽

Tertiary Hospital ◽

Observational Prospective Cohort Study ◽

Data History ◽

The City ◽

Second Wave ◽

Study Setting

Objectives: Comparison between patients admitted to the Intensive Care Unit (ICU) with ventilatory support during the first and second wave (Gamma variant) of COVID 19 in a tertiary hospital in the City of Buenos Aires. Design: Descriptive, observational, prospective cohort study. Setting: ICU of an acute general hospital in Argentina. Patients: Adult patients with COVID-19 admitted consecutively to the ICU. Intervention: Admission to ICU. Main variables of interest: Demographic and laboratory data, history, duration of MV, mortality. Results: 44 patients were recruited during the first wave, and 80 in the second. Significant differences were observed in the second wave for age (60, [SD 11]; vs 68 [SD 11]; p <0.01), days with symptoms (9 [SD 5]; vs 4.5 [SD 3]; p <0.01), duration of MV (10 days [SD 7]; vs 16 [SD 13]; p <0.01), Ferritin (1450 mcg / l [SD 547]; vs 941 mcg / l [ SD 593]; p 0.04) and use of antibiotics (97% vs 45% p <0.01). There was no difference in mortality (66% vs 78% p 0.14) but there was in its primary causes; being more frequent hypoxemia associated with sepsis in the second wave (40% vs 3.4% p <0.01) and hypoxemia and multiorgan failure in the first (28% vs 4% p <0.01). Conclusions: During the second wave of the pandemic, due to Gamma variant, more patients were admitted to our unit, younger, with a longer evolution time, a shorter time on MV and a greater inflammatory response, with no difference in mortality, although there was a difference in its causes.

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Risk Factors Associated with Vancomycin-ResistantEnterococcusin Intensive Care Unit Settings in Saudi Arabia

Interdisciplinary Perspectives on Infectious Diseases ◽

10.1155/2013/369674 ◽

2013 ◽

Vol 2013 ◽

pp. 1-4 ◽

Cited By ~ 7

Author(s):

Mahmoud Shorman ◽

Jaffar A. Al-Tawfiq

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Saudi Arabia ◽

Intensive Care ◽

Antimicrobial Agents ◽

Multiorgan Failure ◽

Tertiary Hospital ◽

Oral Contrast ◽

Factors Associated ◽

Icu Admission

Background. Vancomycin-resistant enterococci (VRE) are significant nosocomial pathogens worldwide. There is one report about the epidemiology of VRE in Saudi Arabia.Objective. To determine the risk factors associated with VRE infection or colonization in intensive care unit (ICU) settings.Design. This is a descriptive, epidemiologic hospital-based case-control study of patients with VRE from February 2006 to March 2010 in ICU in a tertiary hospital in Saudi Arabia.Methods. Data were collected from hospital records of patients with VRE. The main outcome measure was the adjusted odds ratio estimates of potential risk factors for VRE.Results. Factors associated with VRE included ICU admission for multiorgan failure, chronic renal failure, prior use of antimicrobial agents in the past three months and before ICU admission, gastrointestinal oral contrast procedure, and hemodialysis. Being located in a high risk room (roommate of patients colonized or infected with VRE) was found to be protective.Conclusions. Factors associated with VRE acquisition are often complex and may be confounded by local variables.

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Extracorporeal Cytokine Removal in Critically Ill COVID-19 Patients: A Case Series

Frontiers in Medicine ◽

10.3389/fmed.2021.760435 ◽

2021 ◽

Vol 8 ◽

Author(s):

Marcell Virág ◽

Máté Rottler ◽

Klementina Ocskay ◽

Tamás Leiner ◽

Balázs Horváth ◽

...

Keyword(s):

Intensive Care Unit ◽

Critically Ill ◽

Randomized Trials ◽

Statistical Significance ◽

Laboratory Data ◽

Case Series ◽

Report Data ◽

Hospital Acquired ◽

Second Wave ◽

Bacterial Superinfection

Introduction: Extracorporeal hemoadsorption (HA) is a potential adjunctive therapy in severe cases of COVID-19 associated pneumonia. In this retrospective study we report data from critically ill patients treated with HA during the first and second wave of the pandemic.Patients and Methods: All patients, who received HA therapy with CytoSorb within the first 96 h of intensive care unit (ICU) admission without hospital-acquired bacterial superinfection, were included. Clinical and laboratory data were collected: on admission, before (TB) and after (TA) HA therapy.Results: Out of the 367 COVID-19 cases, 13 patients were treated with CytoSorb, also requiring mechanical ventilation and renal replacement therapy. All patients were alive at the end of HA, but only 3 survived hospital stay. From TB-TA there was a tendency of decreasing norepinephrine requirement: 193.7 [IQR: 34.8–270.4] to 50.2 [6.5–243.5] ug/kg/day and increasing PaO2/FiO2 ratio 127.8 (95% CI: 96.0–159.6) to 155.0 (115.3–194.6) mmHg but they did not reach statistical significance (p = 0.14 and 0.58, respectively). Treatment related adverse events were not reported.Conclusion: The treatment was well-tolerated, and there was a tendency toward an improvement in vasopressor need and oxygenation during the course of HA. These observations render the need for prospective randomized trials.

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Surgical Admissions and Treatment Outcomes at a Tertiary Hospital Intensive Care Unit in Ethiopia: A Two-Year Review

Ethiopian Journal of Health Sciences ◽

10.4314/ejhs.v30i5.11 ◽

2020 ◽

Vol 30 (5) ◽

Author(s):

Kirubel Abebe ◽

Tesfaye Negasa ◽

Fitsum Argaw

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Treatment Outcomes ◽

Ventilatory Support ◽

Tertiary Hospital ◽

Surgical Patients ◽

Surgical Intensive Care Unit ◽

Surgical Intensive Care ◽

Medical College ◽

Generalized Peritonitis

BACKGROUND፡ Intensive Care Unit (ICU) is a special unit where critically ill patients who require advanced respiratory or hemodynamic support are admitted. Little has been published about surgical intensive care unit patients in Ethiopia. The aim of this study was to assess the pattern of admission and treatment outcomes of adult surgical patients admitted to the Intensive Care Unit at St. Paul’s Hospital Millennium Medical College (SPHMMC).METHODS: A two-year retrospective medical record review of all adult surgical patients admitted to Intensive Care Unit at St. Paul’s Hospital Millennium Medical College .RESULTS: Surgical patients made up 91(22.1%) of 411 admissions of adult intensive care unit.Of these, 82 (M: F = 1.5:1) patients were analyzed. Age ranged from 16 to 82 years with a mean age of 43 years (SD +/-18.2). Emergency admissions accounted for 70(85.4%) cases. The top three primary admission diagnoses were generalized peritonitis secondary to perforated viscus (25,30.5%), bowel obstruction (21,25.6 %) and trauma (13,15.9%). Acute respiratory failure (38,46.3%) and septic shock (23,28.0%) were the leading indications of intensive care unitadmission. Most patients (62,75.6%) received mechanical ventilatory support.The mean length of intensive care unit stay was 7.3 days (SD+/-5.2).Death occurred in 33(40.2%) patients. Mortality was higher in those who stayed for 48hours (OR=5.6;95% CI 1.60-19.69; p=0.007) and in ventilated patients (OR=5.3; 95% CI 1.41-19.98; p=0.013).CONCLUSION:The observed mortality in this review was higher than the one in most reports. It was significantly high in patients who stayed for 48 hours and in those who required mechanical ventilatory support.

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Studying on the Internet 2.0. Practices of university students in the City of Buenos Aires

Comunicación y Sociedad ◽

10.32870/cys.v0i23.69 ◽

2015 ◽

Vol 0 (23) ◽

pp. 195-213 ◽

Cited By ~ 2

Author(s):

Joaquín Linne ◽

Keyword(s):

University Students ◽

Buenos Aires ◽

The Internet ◽

The City

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A 3 years’ Experience of Operated Surgical Neonates Outcome in a Tertiary Hospital of Ain Shams University (Neonatal Intensive Care Unit)

The International Annals of Medicine ◽

10.24087/iam.2017.1.10.323 ◽

2017 ◽

Vol 1 (10) ◽

Author(s):

Nour El-Din Mohamed Abd El-Aal ◽

Mohamed Samy El-Shimi ◽

Manal Sayed Mohamed

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Neonatal Intensive Care ◽

Tertiary Hospital

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International Opera in Nineteenth-century New York

The Oxford Handbook of the Operatic Canon ◽

10.1093/oxfordhb/9780190224202.013.13 ◽

2020 ◽

pp. 244-269

Author(s):

Karen Ahlquist

Keyword(s):

Nineteenth Century ◽

New York ◽

New York City ◽

World War I ◽

Buenos Aires ◽

Considerable Extent ◽

World War ◽

Metropolitan Opera ◽

The City

This chapter charts how canonic repertories evolved in very different forms in New York City during the nineteenth century. The unstable succession of entrepreneurial touring troupes that visited the city adapted both repertory and individual pieces to the audience’s taste, from which there emerged a major theater, the Metropolitan Opera, offering a mix of German, Italian, and French works. The stable repertory in place there by 1910 resembles to a considerable extent that performed in the same theater today. Indeed, all of the twenty-five operas most often performed between 1883 and 2015 at the Metropolitan Opera were written before World War I. The repertory may seem haphazard in its diversity, but that very condition proved to be its strength in the long term. This chapter is paired with Benjamin Walton’s “Canons of real and imagined opera: Buenos Aires and Montevideo, 1810–1860.”

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