scholarly journals Detection of Mycobacterium tuberculosis based on H37Rv binding peptides using surface functionalized magnetic microspheres coupled with quantum dots – a nano detection method for Mycobacterium tuberculosis

Author(s):  
Hua Yang ◽  
Lianhua Qin ◽  
Yilong Wang ◽  
Bingbo Zhang ◽  
Zhonghua Liu ◽  
...  
2014 ◽  
Vol 62 (2) ◽  
pp. 122-130
Author(s):  
Elif Sanem BAYKAL ◽  
Hüseyin GÜDÜCÜOĞLU ◽  
Görkem YAMAN ◽  
Mustafa BERKTAŞ

2007 ◽  
Vol 17 (41) ◽  
pp. 4400 ◽  
Author(s):  
Robert Wilson ◽  
David G. Spiller ◽  
Ian A. Prior ◽  
Rahila Bhatt ◽  
Alistair Hutchinson

Micromachines ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1523
Author(s):  
Kai Song ◽  
Jianwei Lin ◽  
Yafeng Zhuang ◽  
Zhizhong Han ◽  
Jinghua Chen

In this work, carbon dots (CDs) and black phosphorus quantum dots (BPQDs) were used to decorate titanium dioxide to enhance the photoelectrochemical (PEC) properties of the nanocomposites (TiO2@CDs@BPQDs), and the modified nanocomposites were used to sensitively detect DNA. We used the hydrothermal method and citric acid as a raw material to prepare CDs with good dispersion and strong fluorescence properties. BPQDs with a uniform particle size were prepared from black phosphorus crystals. The nanocomposites were characterized by fluorescence spectroscopy, UV-Vis absorption spectroscopy, Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM). The preparation method of the working electrode was explored, the detection conditions were optimized, and the sensitive detection of target DNA was achieved. The results demonstrate that CDs and BPQDs with good optical properties were successfully prepared, and they were successfully combined with TiO2 to improve the PEC performance of TiO2@CDs@BPQDs. The TiO2-based PEC DNA detection method was constructed with a detection limit of 8.39 nM. The constructed detection method has many advantages, including good sensitivity, a wide detection range, and good specificity. This work provides a promising PEC strategy for the detection of other biomolecules.


Peptides ◽  
2012 ◽  
Vol 38 (2) ◽  
pp. 208-216 ◽  
Author(s):  
Diana Marcela Rodríguez ◽  
Marisol Ocampo ◽  
Hernando Curtidor ◽  
Magnolia Vanegas ◽  
Manuel Elkin Patarroyo ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (36) ◽  
pp. 22005-22013
Author(s):  
Qingbao Yang ◽  
Yanhua Qi ◽  
Jingming Zhou ◽  
Yumei Chen ◽  
Chao Liang ◽  
...  

(1) Water-soluble CdSe/ZnS QDs and an anti-FLE monoclonal antibody were used to prepare a fluorescent probe. (2) Primary rapid detection of FLE residues with visual fluorescent detection method.


Author(s):  
Mao Ye ◽  
Wen Yuan ◽  
Leila Molaeipour ◽  
Khalil Azizian ◽  
Alireza Ahmadi ◽  
...  

Abstract Background Mycobacterium tuberculosis (MTB) is responsible for tuberculosis; that continues to be a public health threat across the globe. Furthermore, increasing heteroresistance (HR)-the presence of resistant and susceptible isolates among MTB strains- has been reported from around the world. This phenomenon can lead to full resistance development and treatment failure. Methods We systematically searched the relevant studies in PubMed, Scopus, and Embase (Until October 21, 2020). The study outcomes revealed the weighted pooled prevalence of antibiotic HR in MTB isolates with subgroup analysis by year, quality of study, and heteroresistance detection method. Results A total of 38 studies which had investigated MTB isolates were included in the meta-analysis. Geographically, the highest number of studies were reported from Asia (n  =  24), followed by Africa (n  =  5). Nineteen studies reported HR to isoniazid, with a weighted pooled prevalence of 5% (95% CI 0–12) among 11,761 MTB isolates. Also, there is no important trend for the subgroup analysis by the study period (2001–2014 vs 2015–2017 vs 2018–2020). HR to rifampin was reported in 17 studies, with a weighted pooled prevalence of 7% (95% CI 2–14) among 3782 MTB isolates. HR to fluoroquinolone and ethambutol were reported in 12 and 4 studies, respectively, with weighted pooled prevalence of 10% and 1% among 2153 and 1509 MTB isolates, correspondingly. Conclusion Based on our analysis, HR in MTB isolates with different frequency rate is present worldwide. Thus, the selection of appropriate and reliable methods for HR detection is crucial for TB eradication.


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