scholarly journals OCULAR CLINICAL PROFILE OF PATIENTS WITH PSEUDOEXFOLIATION SYNDROME AND PSEUDOEXFOLIATION GLAUCOMA AT TERTIARY CARE CENTRE IN KASHMIR

2021 ◽  
Vol 9 (12) ◽  
pp. 261-269
Author(s):  
Jasiya Bashir ◽  
◽  
Ejaz Akbar Wani ◽  
Keyword(s):  
Optic Nerve ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Tertiary Care ◽  
Nerve Damage ◽  
Clinical Profile ◽  
Care Centre ◽  
Pseudoexfoliation Glaucoma ◽  
Tertiary Care Centre ◽  
Optic Nerve Damage

Aim: To study the clinical profile of pseudoexfoliation (PEX) syndrome and Pseudoexfoliation glaucoma at tertiary care centre in Kashmir. Materials and Methods: A cross sectional study consisting of 100 PEX and 100 PEXG patiens, attending the general ophthalmology clinic of a tertiary care center in kashmir. All patients underwent a complete ophthalmologic evaluation including recording IOP,gonioscopy and Central Corneal Thickness(CCT). Results: The study cohort comprised 200 patients(100 with PEX and 100 with PEXG). There were 145(72.5) males and 55(27.5%) females. The highest number of patients (120 patients) were from the age group between 61 and 70years. 145(72.5%) patients were involved in outdoor activities.153(76.5%) patients had bilateral involvement of pseudoexfoliationand pseudoexfoliative material was present at anterior lens capsule in 175(49.58%) eyes. Nuclear cataract was predominant type of cataract and was present in 188(48.2%)eyes. Mean IOP was 17.26±7.634mmHg in PEX group and 24.39±4.456mmHg in PEXG group. Gonioscopyshowed open angles in 96.5% of eyes and occludable in 3.5% eyes . Mean central corneal thickness was 531.80±19.127μm. Conclusion: The prevalence of PEX is found to increase with age. Patients with PXG had more severity of optic nerve damage at presentation. Therefore a careful assessment for detection of PEX is warranted and regular follow-up of patients is desired to minimize the extent of optic nerve damage.

A Prospective Study of Patients with Pseudoexfoliation Glaucoma and Its Management in a Tertiary Care Centre in South India

2021 ◽  
Vol 8 (31) ◽  
pp. 2848-2854
Author(s):  
Nishat Sultana ◽  
Priyam Gupta
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Medical Therapy ◽  
Tertiary Care ◽  
Pseudoexfoliation Syndrome ◽  
Age Group ◽  
Care Centre ◽  
Pseudoexfoliation Glaucoma ◽  
Tertiary Care Centre ◽  
Optic Nerve Damage

BACKGROUND Pseudoexfoliation syndrome is the most common identifiable cause of open angle glaucoma worldwide. Pseudoexfoliation glaucoma develops in 50 % of patients with pseudoexfoliation syndrome. The purpose of this study was to assess the clinical profile, intraocular pressure (IOP), gonioscopic findings, disc changes and need for medical or surgical line of management for the control of pseudoexfoliation glaucoma. METHODS It was a prospective hospital based interventional study of 68 consecutive patients diagnosed with pseudoexfoliation glaucoma, who presented to the glaucoma clinic at a tertiary care centre from Nov 2017 to Mar 2019. RESULTS 68 patients diagnosed with pseudoexfoliation glaucoma were evaluated during the study period from November 2017 to March 2019. Male predominance of 43 (63 %) was noticed. Mean age group of study population was 68 years with 44 (65 %) of patients in age group of 61 – 75 years. 55 cases had bilateral pseudoexfoliation. 85 (69 %) eyes had a pressure of > 21 mm of Hg. 97 (79 %) eyes had open angles, 4 (3 %) occludable angles, 22 (18 %) had closed angles. 4 (3 %) of eyes had cup disc ratio < 0.5, 49 (40 %) eyes had cup disc ratio of 0.5 - 0.7, 64 (52 %) had > 0.7 cupping. 38 (31 %) eyes were controlled on medical therapy with topical antiglaucoma medications. In 14 (11 %), eyes were treated with Nd: YAG PI (neodymium-doped yttrium aluminium garnet peripheral laser iridotomy) with medical treatment, 59 (48 %) eyes were taken up for triple procedure. 10 (8 %) eyes could not be controlled using medical therapy and had to be taken for surgical treatment. CONCLUSIONS Pseudoexfoliation glaucoma leads to irreversible visual loss if high IOP is not treated leading to glaucomatous optic nerve damage and visual field loss. The response to medical therapy is poor and needs surgical intervention. KEYWORDS Pseudoexfoliation Glaucoma, Intraocular Pressure, Optic Nerve Damage, Dandruff Like Material

scholarly journals A comparative study of central corneal thickness in diabetics and non-diabetics using ultrasonic pachymetry

2021 ◽  
Vol 7 (3) ◽  
pp. 554-561
Author(s):  
Chinnangolla Viveknandini Reddy ◽  
M H Reddy
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Department Of Ophthalmology

To determine association between central corneal thickness and type 2 diabetes mellitus in patients attending outpatient department of Ophthalmology at a tertiary care centre in North Karnataka.This is a cross-sectional study conducted over a period of April 2018 – September 2020 on patients attending outpatient department of Ophthalmology at a tertiary care centre in North Karnataka. Study includes 168 subjects divided into 3 groups: 40 diabetics whose duration &#62;10 years46 diabetics whose duration ≤10 yearsand 82 controls.Detailed ophthalmic examination was conducted in all patients and central corneal thickness was measured using ultrasound pachymetry. A statistically significant difference was found between mean central corneal thickness of diabetics (534.0581µ - right eye; 534.3605µ - left eye) and non-diabetics (525.8659µ - right eye; 525.8659µ - left eye); p value &#60;0.05. Association between central corneal thickness and age, gender, laterality and duration of diabetes were not statistically significant. Patients with type 2 diabetes mellitus have thicker corneas as compared to non-diabetics. Henceforth, it is important to measure central corneal thickness in all diabetics, as it affects IOP measurement which is vital for early diagnosis and timely treatment of glaucoma.

scholarly journals CLINICAL PROFILE OF INTUSSUSCEPTION IN CHILDREN ADMITTED TO A TERTIARY CARE CENTRE IN KERALA

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Neethu Jose ◽  
Aparna Namboodiripad ◽  
Regi George A N
Keyword(s):  
Tertiary Care ◽  
Spontaneous Resolution ◽  
Reduction Technique ◽  
Clinical Profile ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Hydrostatic Reduction ◽  
Duration Of Hospital Stay ◽  
Study Population

Background and objectives: Intussusception is the commonest cause of bowel obstruction and is one of the common abdominal emergencies in children younger than 2 years of age.The objective of the study was to assess the clinical profile of intussusception in children and the management and the outcome  and  to assess whether the characteristics mentioned in clinical profile are predictive of subsequent management and outcome of the disease. Methods: A hospital based descriptive study conducted in a tertiary care centre in Kerala, using purposive sampling technique. 120 children admitted with diagnosis of intussusception   fulfilling inclusion criteria and whose parents consented for study were included in the study population, during the study period from November 2018 to June 2020. Detailed history, clinical examination including per rectal examination  and USG was done to make diagnosis of intussusception in suspected cases. Follow up is done at 72 hours,1 week after the admission and 1month later. To assess the clinical profile and outcome of patients, frequency and percentage is used. To obtain the association of clinical profile with outcome chi square test is applied. Results: Outcome of the problem was correlated with age, sex, symptoms, risk factors sonological findings treatment protocol and duration of hospital stay. Out of the 120 children in study population, majority were males(65.8%) with male to female ratio 1.9:1 and majority was in the age group 7- 12 months, which is similar to many other similar studies. Maximum number of cases were in the month of February(14.2%) and November(15%).  Majority of the patients(57.5%) presented to healthcare facility within 24 hours of onset of first symptom.Irritability was the most common clinical symptom(62.5%) followed by vomiting(58.3%) and abdominal pain(49.2%). Ileocolic intussusception (96.7%) was the commonest type. Majority of the cases could be managed with hydrostatic saline reduction(73.3%) and significantly lesser number of patient went for surgical intervention(7.5%) and spontaneous resolution(19.2%). Conclusions: Incidence of intussusception is more common among males and more in the 7-12 month age group.  Majority of the cases presented to health care facility within 24 hours of onset of symptom and could be managed with hydrostatic reduction technique and had a shorter duration of hospital stay compared to surgical reduction technique. Even recurrent cases could be managed with hydrostatic saline reduction. Keywords: Intussusception;  Intestinal obstruction;  Hydrostatic reduction; Spontaneous resolution

scholarly journals Clinical profile and risk factors for mortality among COVID-19 inpatients at a tertiary care centre in Bengaluru, India

2021 ◽  
Author(s):  
Yamini Marimuthu ◽  
Radhika Kunnavil ◽  
NS Anil ◽  
Sharath Burugina Nagaraja ◽  
N Satyanarayana ◽  
...  
Keyword(s):  
Risk Factors ◽  
South India ◽  
Linear Models ◽  
Tertiary Care ◽  
Male Gender ◽  
Clinical Profile ◽  
Rank Test ◽  
Care Hospital ◽  
Care Centre ◽  
Tertiary Care Centre

COVID-19 is an emerging viral disease affecting more than 200 countries worldwide and it present with varied clinical profile throughout the world. Without effective drugs to cure COVID-19, early identification and control of risk factors are important measures to combat COVID-19.  This study was conducted to determine the clinical profile and risk factors associated with mortality among COVID-19 patients in a tertiary care hospital in South India. This record-based longitudinal study was conducted by reviewing the case records of COVID-19 patients admitted for treatment from June 2020 to September 2020 in a tertiary care centre in South India. The clinical details, discharge/death details, were collected and entered in MS Excel. Potential risk factors for COVID-19 mortality were analysed using univariate binomial logistic regression, generalized linear models (GLM) with Poisson distribution. Survival curves were made using the Kaplan-Meier method. Log-rank test was used to test the equality of survivor functions between the groups. Out of 854 COVID-19 patients, 56.6% were men and the mean (standard deviation) age was 45.3(17.2) years. The median survival time was significantly lesser in male COVID-19 patients (16 days) as compared to female patients (20 days). Increasing age, male gender, patients presenting with symptoms of fever, cough, breathlessness, smoking, alcohol consumption, comorbidities were significantly associated with mortality among COVID-19 patients. Patients with older age, male gender, breathlessness, fever, cough, smoking and alcohol and comorbidities need careful observation and early intervention.  Public health campaigns aimed at reducing the prevalence of risk factors like diabetes, hypertension, smoking and alcohol use are also needed.

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