Bazı Yabancı Ot ve Kültür Bitkisi Tohumlarının Çimlenmesine Yarpuz (Mentha pulegium L.) Uçucu Yağının Etkileri

An ethnopharmacological survey was carried out among 224 informants to collect the information on medicinal plants used for the traditional treatment of female infertility in the Fes, Meknes and Boulemane region. In total, 63 plant species belonging to 29 families were used against female infertility. The most frequently cited plants were Lavandula officinalis (26.33%), Mentha pulegium (13.83%), Mentha suaveolens (11.16%), Rosmarinus officinalis (10.71%) and Petroselinum sativum (8.03%). Furthermore, the present study represents a useful documentation for the preservation of this knowledge about medicinal plants and for the amelioration of women reproductive health.

Download Full-text

Phytotherapy for wound healing: The most important herbal plants in wound healing based on Iranian etnobotanical documents

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557520666201119122608 ◽

2020 ◽

Vol 20 ◽

Cited By ~ 1

Author(s):

Kamal Solati ◽

Mehrdad Karimi ◽

Mahmoud Rafieian-Kopaei ◽

Naser Abbasi ◽

Saber Abbaszadeh ◽

...

Keyword(s):

Wound Healing ◽

Medicinal Plants ◽

Aloe Vera ◽

Datura Stramonium ◽

New Drugs ◽

Mentha Pulegium ◽

Accelerate Wound Healing ◽

Healing Tissue ◽

Herbal Plants ◽

Echium Amoenum

: Wound healing is a process which starts with inflammatory response after damage occurrence. This process happens by restoring the wound surface coating tissue, migrating fibroblasts to form the needed collagen, forming a healing tissue and finally contortion and extraction of the wound. Today, various drugs are used to heal the wound. However, the used drugs to repair wounds have some defects and side effects. In spite of all attempts to accelerate wound healing definitely, no safe drug has been introduced for this purpose. Therefore, the necessity of identifying herbal plants in ethnopharmacology and ethnobotany documents with healing effect is felt essential. In this article we tried to review and present Iranian effective medicinal plants and herbal compounds used for wound healing. Searching was performed on databases including ISI Web of Science, PubMed, PubMed Central, Scopus, ISC, SID, Magiran and some other databases. The keywords used included wound healing, skin treatment, medicinal plants, ethnobotany, and phytotherapy. In this regard, 139 effective medicinal plants on wound healing were identified based on ethnopharmacology and ethnobotanical sources of Iran. Medicinal plants such as Salvia officinalis, Echium amoenum, Verbascum spp., G1ycyrrhiza glabra, Medicago sativa, Mentha pulegium, Datura stramonium L., Alhagi spp., Aloe vera, Hypericum perforatum, Pistacia atlantica and Prosopis cineraria were the most important and effective medicinal plants on wound healing in Iran. These native Iranian medicinal plants are full of antioxidants and biological compounds and might be used for wound healing and preparation of new drugs.

Download Full-text

Vasorelaxant and Antihypertensive Effects of Mentha pulegium L. in Rats: An in vitro and in vivo Approach

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1871530320666200909093908 ◽

2020 ◽

Vol 20 ◽

Author(s):

Mohammed Ajebli ◽

Mohamed Eddouks

Keyword(s):

Blood Pressure ◽

Acute Experiment ◽

Antihypertensive Activity ◽

Mentha Pulegium ◽

In Vitro Experiment ◽

Arterial Blood ◽

Dose Dependent ◽

Ca2 Channels

Aims and objective: The aim of the study was to investigate the effect of aqueous aerial part extract of Mentha pulegium L. (Pennyrile) (MPAE) on arterial pressure parameters in rats. Background: Mentha pulegium is a medicinal plant used to treat hypertension in Morocco. Material and methods: In the current study, MPAE was prepared and its antihypertensive activity was pharmacologically investigated. L-NAME-hypertensive and normotensive rats have received orally MPAE (180 and 300 mg/kg) during six hours for the acute experiment and during seven days for the sub-chronic treatment. Thereafter, systolic, diastolic, mean arterial blood pressure and heart rate were evaluated. While, in the in vitro experiment, isolated denuded and intact thoracic aortic rings were suspended in a tissue bath system and the tension changes were recorded. Results: A fall in blood pressure was observed in L-NAME-induced hypertensive treated with MPAE. The extract also produced a dose-dependent relaxation of aorta pre-contracted with NE and KCl. The study showed that the vasorelaxant ability of MPAE seems to be exerted through the blockage of extracellular Ca2+ entry. Conclusion: The results demonstrate that the extract of pennyrile exhibits antihypertensive activity. In addition, the effect may be, at least in part, due to dilation of blood vessels via blockage of Ca2+ channels.

Download Full-text

Mentha pulegium Aqueous Extract Exhibits Antidiabetic and Hepatoprotective Effects in Streptozotocin-Induced Diabetic Rats

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1871530318666181005102247 ◽

2019 ◽

Vol 19 (3) ◽

pp. 292-301

Author(s):

Omar Farid ◽

Naoufel Ali Zeggwagh ◽

Fadwa EL Ouadi ◽

Mohamed Eddouks

Keyword(s):

Blood Glucose ◽

Glucose Tolerance ◽

Aqueous Extract ◽

Morphometric Analysis ◽

Diabetic Rats ◽

Mentha Pulegium ◽

Glucose Levels ◽

Histological Sections ◽

Blood Glucose Levels ◽

Liver And Pancreas

Objective: The aim of this work was to evaluate the antihyperglycemic activity of aerial parts aqueous extract (A.P.A.E) of Mentha pulegium (M. pulegium) on blood glucose levels in normal and streptozotocin(STZ)-induced diabetic rat. The glucose tolerance was evaluated in normal rats. Moreover, the histological sections and morphometric analysis at the liver and pancreas have been carried out in this investigation both in normal and STZ-diabetic rats. Methods: The effect of A.P.A.E of M. pulegium (20 mg/kg) on blood glucose levels was investigated in normal and diabetic rats (n=6). Histopathological changes in liver and pancreas were examined under phase contrast microscope and a preliminary screening for various bioactive constituents was realized according to standard methods. Key Findings: Both single and repeated oral administration of A.P.A.E (20 mg/kg) caused a significant reduction in blood glucose levels in STZ-diabetic rats (p<0.0001). The morphometric analysis and histological sections realized in pancreas and liver have showed the beneficial effect of the A.P.A.E in cellular population. According to oral glucose tolerance test (OGTT), the aqueous extract has revealed an improvement of glucose tolerance in normal rat. Furthermore, the preliminary phytochemical screening of A.P.A.E of M. pulegium has demonstrated the presence of various metabolite compounds including polyphenols, flavonoids, terpenoids tannins, cyanidins, sesquiterpenes, and glycosides. Conclusion: We conclude that the A.P.A.E of M. pulegium (20 mg/kg) exhibits a potent antihyperglycemic activity in STZ diabetic rats.

Download Full-text

Mentha pulegium: de Belair, G., Rhazi, L. & Lansdown, R.V.

IUCN Red List of Threatened Species ◽

10.2305/iucn.uk.2014-1.rlts.t164256a42395474.en ◽

2013 ◽

Author(s):

Keyword(s):

Mentha Pulegium

Download Full-text

Wound-healing activity of Algerian Lavandula stoechas and Mentha pulegium extracts: from traditional use to scientific validation

Plant Biosystems - An International Journal Dealing with all Aspects of Plant Biology ◽

10.1080/11263504.2020.1869117 ◽

2020 ◽

pp. 1-20

Author(s):

Faiza Baali ◽

Sabah Boumerfeg ◽

Amel Boudjelal ◽

Marcella Denaro ◽

Giovanna Ginestra ◽

...

Keyword(s):

Wound Healing ◽

Mentha Pulegium ◽

Traditional Use ◽

Lavandula Stoechas ◽

Scientific Validation ◽

Wound Healing Activity

Download Full-text

New menthone type of Mentha pulegium L. volatile oil from northwest Iran

Czech Journal of Food Sciences ◽

10.17221/165/2009-cjfs ◽

2011 ◽

Vol 29 (No. 3) ◽

pp. 285-290 ◽

Cited By ~ 10

Author(s):

M.B. Hassanpouraghdam ◽

A.B. Akhgari ◽

M.A. Aazami ◽

J. Emarat-Pardaz

Keyword(s):

Essential Oil ◽

Volatile Oil ◽

Oil Composition ◽

Mentha Pulegium ◽

Food Industries ◽

Aerial Parts ◽

Sesquiterpene Hydrocarbons ◽

Main Class ◽

Northwest Iran ◽

A Minor

The constituents of the volatile oil of air-dried aerial parts of Mentha pulegium L. (Lamiaceae) plants wildly growing in Northwest Iran were analysed by GC/MS. 46 components were identified, comprising 96.6% of the essential oil. Monoterpenes (78.9%) were the main class of the identified components followed by a minor proportion of sesqui-<br />terpenes (11%). Oxygenated monoterpenes (75.3%) were the major subclass of volatile oil components with menthone (38.7%), menthol (11.3%), neomenthol (10.5%), and pulegone (6.8%) as major compounds. Sesquiterpene hydrocarbons (10.6%) were the highlighted subclass of 15 carbons sesquiterpenoidal compounds with (E)-caryophyllene (4.9%) and β-cubebene (2.5%) as their principle representatives. Furthermore, menthyl acetate (C<sub>12</sub> acetylated monoterpene derived compound) was contained considerable amounts (5.2%) in the essential oil. In total, volatile oil composition of M. pulegium L. plants studied in the present experiment was characterised as a new menthone type with appreciable amounts of menthol and neomenthol, and it could be used as a potential source of these high value monoterpenes in pharmaceutical and food industries.

Download Full-text