CNS-active drugs increase risk of falls in the elderly

2002 ◽  
Vol &NA; (1368) ◽  
pp. 21
Author(s):  
&NA;
Author(s):  
Hand F Mahmoud ◽  
Hebatullah EMZ Elmedany

Introduction: Fall is considered by far one of the leading causes of morbidity and mortality in the elderly population. Fall is almost always multifactorial. This study looks into the relation between different comorbidities, polypharmacy and falls.Methods: A descriptive and prospective study, the study population comprised 150 elderly patients aged > 60 years old, males and females, patients with previous history of falls are excluded. Comorbidity burden, polypharmacy and risk of falls were assessed.Results and Discussion: There was a significant positive correlation between Number of comorbidities, medications and risk of falls and there was a significant association between high risk of falls and presence of DM, PVD, OLD CVA and UI. Also, there was a significant positive correlation between age and risk of falls.Conclusion: Multiple comorbidities, polypharmacy and increasing age increase risk of falls.International Journal of Human and Health Sciences Vol. 06 No. 01 January’22 Page: 75-79


2015 ◽  
Vol 24 (01) ◽  
pp. 7-10 ◽  
Author(s):  
M. Pfeifer ◽  
M. Sinaki

SummaryThe objective of exercise in the treatment of osteoporosis is to improve axial stability through strengthening of back extensor muscles. Therefore, a back extension exercise program specific to one’s musculoskeletal competence and pain can be performed in a sitting position and later advanced to the prone position. When fragility is resolved, back extension is performed against resistance applied to the upper back. A significant reduction in back pain, kyphosis, and risk of falls and an improvement in the level of physical activity have been achieved through the SPEED (Spinal Proprioceptive Extension Exercise Dynamic) program. In addition, the application of a “Posture Training Support” (PTS) using a backpack may decrease kyphosis and pain related not only to compression fractures but also reduce iliocostal friction. Therapeutic exercise should address osteo - porosis-related deformities of axial posture, which can increase risk of fall and fracture. Thus, the role of a therapeutic exercise program is to increase muscle strength safely, decrease immobility-related complications, and prevent fall and fracture. As with pharmacotherapy, therapeutic exercises are individualized.


2021 ◽  
pp. 1-9
Author(s):  
In-Gyu Yoo ◽  
Ji-Hye Do

BACKGROUND: Posture control involves complex reactions of dynamic and static movements, and various sensory inputs. There is evidence that exercise using multisensory stimulation is moderately effective in improving the balance of the elderly. OBJECTIVE: The main purpose of this paper was to examine the existing literature to validate the effectiveness and applicability of multisensory stimulation training. METHODS: All relevant literature published as of June 1, 2020 in four prominent databases was searched (Embase, PubMed, PsycINFO, and Web of science) using the five-stage review framework proposed by Arksey and O’Malley. RESULTS: Multisensory stimulation training was more effective when vestibular and somatosensory were combined with visual stimuli, and differences in effectiveness compared to the effectiveness of existing treatments were confirmed. However, most of the reviewed papers are compared to simple strength training, and studies that compare the effects of multisensory stimulation training by setting a control group are still lacking. CONCLUSION: Further research is required to further elucidate the training conditions and treatment environment for multisensory training for the elderly at risk of falls and to provide strategies to improve treatment methods. In addition, a study that can evaluate user satisfaction in a way that best shows the treatment effect using qualitative research methods will be needed.


2007 ◽  
Vol 22 (3) ◽  
pp. 359-364 ◽  
Author(s):  
Ming HUO ◽  
Dongmei CHANG ◽  
Hitoshi MARUYAMA
Keyword(s):  

2021 ◽  
pp. 56-57
Author(s):  
Rohit Arora ◽  
D.K Sharma

Hypertension is a common disease in the elderly associated with signicant morbidity and mortality. Due to the complexity of this population, the optimal target of blood pressure (BP) control is still controversial. In this article, we conduct a literature review of trials published in English in the last 10 years which were specically designed to study the efcacy and safety of various BP targets in patients who are 70 years or older. Using these criteria, we found that the benets in the positive studies were demonstrated even with a minimal BPcontrol (systolic BP[SBP] <150 mmHg) and continued to be reported for a SBP<120 mmHg. On the other hand, keeping SBP<140 mmHg seemed to be safely achieved in elderly patients. Although the safety of lowering SBP to <120 mmHg is debated, Systolic Blood Pressure Intervention Trial study has shown no increased risk of falls, fractures, or kidney failure in elderly patients with SBP lower than this threshold. While the recent guidelines recommended to keep BP <130/80 mmHg in the elderly, more individualized approach should be considered to achieve this goal in order to avoid undesirable complications. Furthermore, further studies are required to evaluate BPtarget in very old patients or those with multiple comorbidities.


Author(s):  
JÚLIO BENVENUTTI BUENO DE CAMARGO ◽  
RAFAEL SAKAI ZARONI ◽  
TIAGO VOLPI BRAZ ◽  
MOISÉS DIEGO GERMANO ◽  
JHENIPHER MONIKY ROSOLEM ◽  
...  

Aging is characterized by a progressive decline in function and morphological aspects of biological tissues, with especial regards to cardiovascular and musculoskeletal systems. In this sense, exercise has been shown to strongly counteract these aging-induced detrimental effects. Endurance exercise (EE) has been shown to reduce the rate of decline of factors related to cardiorespiratory fitness. In addition, the adoption of resistance training (RT) may also induce relevant adaptations, especially related to increased muscle strength and power levels, that have shown to positively influence functional aspects as improved balance and reduced risk of falls in the elderly population. Then, the aim of the present study is to briefly review the exercise literature regarding its mechanisms that could potentially present “antiaging” effects.


Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Stacey Knight ◽  
Heidi T May ◽  
Benjamin D Horne ◽  
Jeffrey L Anderson ◽  
Joseph B Muhlestein

Background: It has been suggested that taking statins may increase the risk of a fall due to myopathy. However, studies have reported contradictory evidence regarding the association between statin use and fall risk. The purpose of this study was to determine whether taking statins increases the risk of falls in patients undergoing a coronary angiography. Methods: The study population was a subset subjects from the Intermountain Heart Collaborative Study (n=1011). A subject was considered as taking statins if they were discharged with statins and had record of a filled statin prescription (n=810); they were considered as not taking statins if they had no prior statin use, were not discharged with statins, and had no record of a filled statin prescription (n=203). Electronic medical records were queried to determined medically treated falls (ICD-9: E8850-E8869; E888x) within 5 years of their angiography. Univariate association testing between falls and cardiovascular medications, co-morbidities, and demographic factors were done. Multivariate Cox regression analysis was used to test the association between statin use and fall risk while adjusting for the other factors found to be associated with fall risk in the univariate analyses. Results: Of the 1011 subjects, 112 (11%) had at least one medically-treated fall within 5 years. In the univariate analyses, statin use (p=0.024), age (p<0.001), sex (p=0.001), hypertension (p=0.040), diabetes (p<0.001), history of atrial fibrillation (AF) (p<0.001), and coumadin use (p=0.009) were associated with falls. Even after adjustment by other risk factors, statin use was associated with a decrease risk of a fall (HR=0.62; 0.40, 0.94). The factors conferring the most risk of a fall were diabetes, AF, and age (Table 1). Conclusions: Statin use was associated with a 1.6-fold decreased risk for a medically-treated fall. This suggests that clinicians may not need to caution patients taking statins regarding an increase risk of falls.


2021 ◽  
Vol 4 (2) ◽  
pp. 81-88
Author(s):  
Gamze Dilek ◽  
Yalkin Calik ◽  
Kagan Ozkuk
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document