Editorial [Hot Topic: Analytical Methods Capable of Sensing Biological and Chemical Warfare Agents and their Degradation Products Based on Bio-Organic Chemistry (Guest Editor: Ji Hoon Lee Related Compounds) ]

2007 ◽  
Vol 11 (3) ◽  
pp. 239-239
Author(s):  
Ji Hoon Lee
Keyword(s):  
Organic Chemistry ◽  
Guest Editor ◽  
Analytical Methods ◽  
Degradation Products ◽  
Chemical Warfare Agents ◽  
Chemical Warfare ◽  
Warfare Agents ◽  
Related Compounds

scholarly journals Novel analytical approaches to determination of chemical warfare agents and related compounds for verification of nonproliferation of chemical weapons

2017 ◽  
Vol 89 (10) ◽  
pp. 1491-1503 ◽  
Author(s):  
Igor V. Rybalchenko ◽  
Igor A. Rodin ◽  
Timur M. Baygildiev ◽  
Andrey N. Stavrianidi ◽  
Arcady V. Braun ◽  
...  
Keyword(s):  
Analytical Methods ◽  
Sulfur Mustard ◽  
Degradation Products ◽  
Chemical Warfare Agents ◽  
Chemical Warfare ◽  
Chemical Weapons ◽  
Mass Spectral ◽  
Fast Screening ◽  
Warfare Agents ◽  
Analytical Approaches

AbstractIn this paper a summary of the author’s approaches for investigation of the mass spectral behavior of some chemical warfare agents (CWAs), their degradation products and metabolites, as well as the results of development of analytical methods for confirmation of nerve and blister agents application are presented. Hydrolysis and oxidation metabolites of nerve agents, sulfur mustard and lewisite were used as biomarkers of the exposure. Sensitive analytical methods have been developed for their detection, based mainly on tandem mass spectrometry coupled with liquid chromatography. Several techniques for fast screening of CWAs degradation products based on capillary electrophoresis were also proposed. Some of developed approaches were successfully applied in the frame of the proficiency testing system of the Organization for the Prohibition of Chemical Weapons.

Mass spectrometric study of selected precursors and degradation products of chemical warfare agents

2007 ◽  
Vol 42 (12) ◽  
pp. 1550-1561 ◽  
Author(s):  
Barbora Papoušková ◽  
Petr Bednář ◽  
Iveta Fryšová ◽  
Jakub Stýskala ◽  
Jan Hlaváč ◽  
...  
Keyword(s):  
Degradation Products ◽  
Chemical Warfare Agents ◽  
Mass Spectrometric Study ◽  
Chemical Warfare ◽  
Mass Spectrometric ◽  
Spectrometric Study ◽  
Warfare Agents

Analysis of degradation products of chemical warfare agents using capillary electrophoresis

The Analyst ◽  
2011 ◽  
Vol 136 (20) ◽  
pp. 4103 ◽  
Author(s):  
Svetlana S. Aleksenko ◽  
Pierre Gareil ◽  
Andrei R. Timerbaev
Keyword(s):  
Capillary Electrophoresis ◽  
Degradation Products ◽  
Chemical Warfare Agents ◽  
Chemical Warfare ◽  
Warfare Agents

Verification of the Chemical Weapons Convention: Mass Spectrometry of Alkyl Methylphosphonofluoridates

1994 ◽  
Vol 47 (11) ◽  
pp. 2065 ◽  
Author(s):  
VT Borrett ◽  
RJ Mathews ◽  
ER Mattsson
Keyword(s):  
Analytical Data ◽  
Chemical Warfare Agents ◽  
Chemical Warfare ◽  
Chemical Weapons ◽  
Screening Methods ◽  
Industrial Sites ◽  
Chemical Weapons Convention ◽  
Warfare Agents ◽  
The Individual ◽  
Related Compounds

Under the provisions of the United Nations Chemical Weapons Convention (CWC), certain parts of chemical industry will be monitored to verify compliance with the Convention. This will include analysis of samples from industrial sites to check for the presence or absence of chemical warfare related compounds. One of the problems in screening the chemicals to be monitored under the CWC is that certain classes of chemical warfare agents are represented as families of chemicals, with many of the individual chemicals having no analytical data available. One example is the alkyl methylphosphonofluoridate family with an alkyl ester substituent from CH3 to C10H21. In this work, the mass spectra of 60 alkyl methylphosphonofluoridate family members have been studied to enable the development of rapid on-site screening methods for this family of chemicals.

Ion-Pair Single-Drop Microextraction Determinations of Degradation Products of Chemical Warfare Agents in Water

2013 ◽  
Vol 76 (11-12) ◽  
pp. 679-685 ◽  
Author(s):  
Yang Ki Park ◽  
Woo Young Chung ◽  
Byungsub Kim ◽  
Young-sik Kye ◽  
Moon-sik Shin ◽  
...  
Keyword(s):  
Degradation Products ◽  
Chemical Warfare Agents ◽  
Ion Pair ◽  
Chemical Warfare ◽  
Single Drop ◽  
Single Drop Microextraction ◽  
Warfare Agents

Conventional analytical methods for chemical warfare agents

2002 ◽  
Vol 74 (12) ◽  
pp. 2281-2291 ◽  
Author(s):  
H. H. Hill ◽  
S. J. Martin
Keyword(s):  
Ion Mobility ◽  
Analytical Methods ◽  
Analytical Data ◽  
Chemical Warfare Agents ◽  
Chemical Warfare ◽  
Chemical Weapons ◽  
Field Verification ◽  
Detection And Identification ◽  
Chemical Weapons Convention ◽  
Warfare Agents

Analytical methods that are currently used for the detection and identification of chemical warfare agents are reviewed and classified by the number of dimensions of information they provide. Single dimensional sensors target specific compounds or classes of compounds. Although they can be less expensive and more portable than multidimensional sensors, multidimensional sensors detect a broader threat spectrum with greater precision and accuracy. The recommendation for analytical field verification during inspections under the Chemical Weapons Convention (CWC) is to use simple two-dimensional analytical methods, such as gas chromatography (GC) or ion mobility spectrometry (IMS), for on-site screening of chemical weapons (CW) agents or to fully equip a modern, mobile analytical laboratory located in an airplane, which can be moved rapidly throughout the world to each inspection site and provide high-quality analytical data on-site.

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