scholarly journals Gene Expression Signatures of Lymph Node Metastasis in Oral Cancer: Molecular Characteristics and Clinical Significances

2010 ◽  
Vol 6 (4) ◽  
pp. 294-307 ◽  
Author(s):  
Xiqiang Liu ◽  
Antonia Kolokythas ◽  
Jianguang Wang ◽  
Hongzhang Huang ◽  
Xiaofeng Zhou
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cancer ◽  
Molecular Characteristics ◽  
Node Metastasis ◽  
Gene Expression Signatures

Prediction of Lymph Node Metastasis in Patients with Bladder Cancer Using Whole Transcriptome Gene Expression Signatures

2016 ◽  
Vol 196 (4) ◽  
pp. 1036-1041 ◽  
Author(s):  
Roland Seiler ◽  
Lucia L. Lam ◽  
Nicholas Erho ◽  
Mandeep Takhar ◽  
Anirban P. Mitra ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bladder Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Gene Expression Signatures ◽  
Whole Transcriptome

scholarly journals Gene expression pattern in oral cancer cervical lymph node metastasis

2006 ◽  
Author(s):  
Yoshikuni Kato ◽  
Katsuhiro Uzawa ◽  
Kengo Saito ◽  
Dai Nakashima ◽  
Masaki Kato ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cancer ◽  
Expression Pattern ◽  
Cervical Lymph Node ◽  
Gene Expression Pattern ◽  
Cervical Lymph Node Metastasis ◽  
Node Metastasis

scholarly journals Increased Expression of VANGL1 is Predictive of Lymph Node Metastasis in Colorectal Cancer: Results from a 20-Gene Expression Signature

2021 ◽  
Vol 11 (2) ◽  
pp. 126
Author(s):  
Noshad Peyravian ◽  
Stefania Nobili ◽  
Zahra Pezeshkian ◽  
Meysam Olfatifar ◽  
Afshin Moradi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Candidate Genes ◽  
Case Series ◽  
Gene Expression Signature ◽  
Gene Panel ◽  
Expression Levels ◽  
Node Metastasis

This study aimed at building a prognostic signature based on a candidate gene panel whose expression may be associated with lymph node metastasis (LNM), thus potentially able to predict colorectal cancer (CRC) progression and patient survival. The mRNA expression levels of 20 candidate genes were evaluated by RT-qPCR in cancer and normal mucosa formalin-fixed paraffin-embedded (FFPE) tissues of CRC patients. Receiver operating characteristic curves were used to evaluate the prognosis performance of our model by calculating the area under the curve (AUC) values corresponding to stage and metastasis. A total of 100 FFPE primary tumor tissues from stage I–IV CRC patients were collected and analyzed. Among the 20 candidate genes we studied, only the expression levels of VANGL1 significantly varied between patients with and without LNMs (p = 0.02). Additionally, the AUC value of the 20-gene panel was found to have the highest predictive performance (i.e., AUC = 79.84%) for LNMs compared with that of two subpanels including 5 and 10 genes. According to our results, VANGL1 gene expression levels are able to estimate LNMs in different stages of CRC. After a proper validation in a wider case series, the evaluation of VANGL1 gene expression and that of the 20-gene panel signature could help in the future in the prediction of CRC progression.

Mucin gene expression and lymph node metastasis in early gastric cancer

1998 ◽  
Vol 114 ◽  
pp. A623
Author(s):  
HR Kim ◽  
SJ Pang ◽  
HY Jung ◽  
WS Hong ◽  
YI Min ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Early Gastric Cancer ◽  
Node Metastasis ◽  
Mucin Gene

Prediction of lymph node metastasis by gene expression profiling in patients with primary resected lung cancer

Lung Cancer ◽  
2009 ◽  
Vol 64 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Yasumitsu Moriya ◽  
Akira Iyoda ◽  
Yasuhiro Kasai ◽  
Takashi Sugimoto ◽  
Junya Hashida ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lung Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Node Metastasis
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