A Short Review of Analytical Methods for the Determination of Estramustine Phosphate and its Metabolites in Biological Samples

2005 ◽  
Vol 1 (2) ◽  
pp. 195-201
Author(s):  
Massimo Breda ◽  
Christopher James
Keyword(s):  
Biological Samples ◽  
Analytical Methods ◽  
Short Review ◽  
Estramustine Phosphate

scholarly journals Instrumental Analysis of Chlordiazepoxide in Different Matrices

2021 ◽  
pp. 1-10
Author(s):  
Lobna M. Abdel-Aziz ◽  
Ahmed A. Soror ◽  
Ahmed A. Hassan ◽  
Ahmed S. Ali ◽  
Ahmed A. Hafez ◽  
...  
Keyword(s):  
Literature Review ◽  
Biological Samples ◽  
Analytical Methods ◽  
Degradation Products ◽  
Electrochemical Techniques ◽  
Pharmacological Action ◽  
Pure Form ◽  
Instrumental Analysis ◽  
The World

Chlordiazepoxide is considered one of most important sedative and hypnotic benzodiazepines drugs which is currently used all over the world with the increased rate of anxiety drugs. In this literature review, we will introduce the pharmacological action of this drug in addition to most of up-to-date reported methods that have been developed for determination of chlordiazepoxide in its pure form, combined form with other drugs, combined form with degradation products, and in biological samples. Most of the reported analytical methods will focus on spectroscopic, chromatographic and electrochemical techniques.

scholarly journals Analytical Methods for Determination of Salbutamol, Ambroxol and Fexofenadine

2020 ◽  
Vol 1 (1) ◽  
pp. 01-11
Author(s):  
Mahmoud Sebaiy
Keyword(s):  
Biological Samples ◽  
Analytical Methods ◽  
Degradation Products ◽  
Review Article ◽  
Pure Form

In this review article, we will introduce all reported methods that have been developed for determination of certain anti-tussive and anti-histaminic drugs such as salbutamol, ambroxol and fexofenadine in their pure form, combined form with other drugs, combined form with degradation products, and in biological samples. We also will shed the light on the most important combination of drugs that are used for treatment of asthma and related diseases.

Modern Analytical Methods of Speciation and Determination of Trace Elements in Inorganic, Organic, and Biological Samples

2018 ◽  
pp. 33-60
Author(s):  
Bogusław Buszewski ◽  
Wojciech Piekoszewski ◽  
Paweł Pomastowski ◽  
Katarzyna Rafińska ◽  
Mateusz Sugajski ◽  
...  
Keyword(s):  
Trace Elements ◽  
Biological Samples ◽  
Analytical Methods ◽  
Modern Analytical

Methodological Aspects of Plant Sterol and Stanol Measurement

2015 ◽  
Vol 98 (3) ◽  
pp. 674-676 ◽  
Author(s):  
Dieter Lütjohann
Keyword(s):  
Sample Preparation ◽  
Biological Samples ◽  
Analytical Methods ◽  
Plant Sterol ◽  
Cholesterol Synthesis ◽  
Surrogate Markers ◽  
Lipid Research ◽  
Detection Techniques ◽  
Methodological Aspects

Abstract Cholesterol, its biosynthetic precursors, its metabolite 5α-cholestanol and plant sterols are widely used today in clinical lipid research as surrogate markers of cholesterol synthesis and absorption. Advances in analytical methods for the determination of serum noncholesterol sterols and stanols within the last century are highlighted. This review focuses on sample preparation, separation, and detection techniques. Various aspects related to sterol and stanol analysis from biological samples are discussed.

scholarly journals Ultra-high performance liquid chromatographic determination of aflatoxin M1 in urine

2015 ◽  
Vol 8 (4) ◽  
pp. 405-413 ◽  
Author(s):  
S. Mohd Redzwan ◽  
R. Jamaluddin ◽  
A.M. Mohd Sokhini ◽  
A.R. Nurul Aqilah ◽  
A. Zuraini ◽  
...  
Keyword(s):  
Biological Samples ◽  
Analytical Methods ◽  
High Performance ◽  
Limit Of Detection ◽  
Extraction Procedure ◽  
Aflatoxin M1 ◽  
Enzyme Linked Immunosorbent Assay ◽  
Fluorescence Detector ◽  
The Mean

The development of analytical methods to detect aflatoxin B1 (AFB1) in foodstuffs and its metabolites in human biological samples is useful for risk assessment. The latter methodology, i.e. the measurement of AFB1 biomarkers, has become important to assess human aflatoxin exposure. AFB1-lysine adduct, AFB1-DNA adduct and urinary aflatoxin M1 (AFM1) are some of the AFB1 biomarkers that can be measured by several analytical methods, such as enzyme-linked immunosorbent assay, radioimmunoassay, and high performance liquid chromatography (HPLC). HPLC coupled to a fluorescence detector is useful and preferable due to its high degree of sensitivity, but the analysis may take time and consume large amount of solvents. Therefore, the present study extrapolated the HPLC method to ultra-HPLC for the determination of urinary AFM1. After the extraction procedure with an immunoaffinity column, chromatographic separation was done using a high performance 1.8 μm microparticulate C18 column. The mean recovery from urine samples spiked with 0.5, 1.0 and 2.0 ng/ml AFM1 was 84.4±4.0%, with acceptable recovery values, interday (6.0±5.3%) and intraday (2.6±0.6%) coefficients of variation. The retention time was 5.7 min. This method was used to measure urinary AFM1 in 71 subjects, of which 13 had AFM1 levels above the limit of detection (0.018 ng/ml). The mean urinary AFM1 level of the positive samples was 18.8±28.6 pg/ml, ranging from 2.4 to 100.4 pg/ml. As this is one of the few studies investigating the occurrence of aflatoxin biomarkers in human biological samples in Malaysia, a study with a larger sample size is necessary to investigate the magnitude of aflatoxin exposure among the population.

scholarly journals Analytical Methods for the Determination of Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) in Biological Samples, Plants and Foods

Biomolecules ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1092 ◽  
Author(s):  
Maroula G. Kokotou
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Biological Samples ◽  
Analytical Methods ◽  
Biological Significance ◽  
Hydroxy Fatty Acids ◽  
Fatty Acid Esters ◽  
Lipid Species ◽  
Acid Esters

Fatty acid esters of hydroxy fatty acids (FAHFAs) constitute a class of recently identified novel lipids exhibiting anti-diabetic and anti-inflammatory effects. Due to their high biological significance, a tremendous effort has been devoted to the development of analytical methods for the detection and quantitation of FAHFAs during the last five years. The analysis of FAHFAs is very challenging due to the great number of possible regio-isomers arising from the great number of possible combinations of FAs with HFAs, and the low abundancies of FAHFAs in biological samples. The aim of this review article is to summarize all the cutting-edge analytical methodologies for the determination of FAHFAs in biological samples, plant tissues and food matrices, with emphasis on extraction and analysis steps. All the analytical methodologies rely on the use of liquid chromatography–mass spectrometry (LC-MS), providing high sensitivity due to the MS detection. Powerful and robust analytical methodologies may highly contribute in studying FAHFAs levels under various biomedical conditions, and facilitate our understanding of the role of these lipid species in physiological and pathological conditions.

Recent trends in analytical methods for the determination of amino acids in biological samples

2018 ◽  
Vol 147 ◽  
pp. 35-49 ◽  
Author(s):  
Yanting Song ◽  
Chang Xu ◽  
Hiroshi Kuroki ◽  
Yiyi Liao ◽  
Makoto Tsunoda
Keyword(s):  
Amino Acids ◽  
Biological Samples ◽  
Analytical Methods ◽  
Recent Trends

Analytical methods for determination of anticoagulant rodenticides in biological samples

2015 ◽  
Vol 253 ◽  
pp. 94-102 ◽  
Author(s):  
Muhammad Imran ◽  
Humera Shafi ◽  
Sardar Ali Wattoo ◽  
Muhammad Taimoor Chaudhary ◽  
Hafiz Faisal Usman
Keyword(s):  
Biological Samples ◽  
Analytical Methods ◽  
Anticoagulant Rodenticides
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