A Comprehensive Study of Pharmacological Behaviors, Nano-formulations, and Applications of Rosemary

2020 ◽  
Vol 10 ◽  
Author(s):  
Rizwana Khatoon ◽  
Md. Aftab Alam ◽  
Pramod Kumar Sharma
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Food Additives ◽  
Modern Medicine ◽  
Rosmarinus Officinalis ◽  
Natural Food ◽  
Therapeutic Effects ◽  
Locomotive Activity ◽  
Rosmarinus Officinalis L

Aim: The purpose of this review paper is to elaborate many nano-formulations of Rosemary which are used against many diseases and also explain the Pharmacological activity of phytocompounds of Rosemary and details about the applications and uses of Rosemary in many fields. Objectives: Rosemary (Rosmarinus officinalis L.) is a medicinal herbal plant, their leaves are used in Europe, America, and Asia as a food additive. It is very valuable, their parts contain many chemical constituents which are very effective against many diseases like diabetes, obesity, cancer, infections and also have antioxidant, anti-inflammation, memory-improvement, etc. properties. Results: In the literature reviewed, Rosmarinus officinalis (rosemary) has shown exciting potential both as a natural food preservative and as a therapeutic agent. Rosemary (Rosmarinus officinalis) essential oil has been extensively studied due to its chemical composition and biological activities. The extract of Rosemary also shows the medicinal properties like anticancer, antimicrobial, antidiabetic, anti-inflammatory etc. From many studies, it was also found that nano-formulation of Rosemary had been developed by using the Rosemary essential oil and its extract which are used in the diagnosis and treatment of many diseases. Conclusion: From the conventional times, therapeutic effects of Rosemary are seen, which is also used in Modern Medicine now days. It had been used as food additives in the conventional times. In renal colic and dysmenorrhea, it is used as an antispasmodic to relieve respiratory disorders and to boost hair development. CNS, cardiac and locomotive activity promotes inhalation and oral administration of Rosemary oil, suggesting the direct effect of one or more of its constituents. Rosemary have curative potential in the therapy and avoidance of bronchial asthma, peptic ulcer, spasmodic disorders, inflammatory illnesses, atherosclerosis, hepatotoxicity, cancer, ischemic heart illness, bad sperm motility, Alzheimer, and may act as antidepressant and anxiolytic properties.

Anti-inflammatory and antialgic actions of a nanoemulsion of Rosmarinus officinalis L. essential oil and a molecular docking study of its major chemical constituents

2017 ◽  
Vol 26 (1) ◽  
pp. 183-195 ◽  
Author(s):  
Raphaelle Sousa Borges ◽  
Emerson Silva Lima ◽  
Hady Keita ◽  
Irlon Maciel Ferreira ◽  
Caio Pinho Fernandes ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Essential Oil ◽  
Chemical Constituents ◽  
Docking Study ◽  
Rosmarinus Officinalis ◽  
Molecular Docking Study ◽  
Anti Inflammatory ◽  
Major Chemical ◽  
Rosmarinus Officinalis L

scholarly journals Synthesis of Piperitone Epoxide and P-Menthane-8-Thiol-3-One from Essential Oils

2020 ◽  
Vol 5 (8) ◽  
pp. 1153-1158
Author(s):  
Abubakar Sani ◽  
Muhammad Sulaiman Rahama
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Chemical Constituents ◽  
Food Additives ◽  
Modern Medicine ◽  
Flowering Plant ◽  
Western Cape ◽  
Growing Up ◽  
Materials Synthesis ◽  
Main Components

Buchu (Barosma betulina) is a small flowering plant found in the family Rutaceae in Western Cape of South Africa, Namibia and Australia, capable of growing up to 2 meters with a simple rounded leaf that produced essential oil of strong peppermint and sweetish smell. The Buchu oil as an essential oil consist of many chemical constituents, the main components includes piperitone, pulegone, piperitone epoxide, iso-menthone, P-menthane-8-thiol3-one, 4-diosphenol. The piperitone epoxide and Pmenthane-8-thiol-3-one constituents in Buchu oil have high commercial values, which extensively used as fragrances in perform, flavor, food additives, tonic and medicinal stimulant in modern medicine in the manufacture of insecticides, antimicrobial, antiinflammatory and antioxidant in cosmetic products. The extinction threat of the plant and chemistry benefit of these chemical constituents initiate scientist with synthetic route for synthesizing the compounds from Eucalyptus dives oil and pennyroyal oil, which are also an essential oils and abundant in nature. In the synthesis, purified piperitone and pulegone from the Eucalyptus dives oil and pennyroyal oil produced two enatiotiomers of piperitone epoxide and P-menthane-8- thiol-3-one respectively. The analytical analysis such infrared and GC-Mc conducted for the starting materials, synthesis processes and synthesize products showed results of significant value in terms chemical reactions and structural re-arrangement.

scholarly journals Ammi Visnaga L., a Potential Medicinal Plant: A Review

Molecules ◽  
2020 ◽  
Vol 25 (2) ◽  
pp. 301 ◽  
Author(s):  
Noha Khalil ◽  
Mokhtar Bishr ◽  
Samar Desouky ◽  
Osama Salama
Keyword(s):  
Essential Oil ◽  
Renal Colic ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Modern Medicine ◽  
Pharmacological Activities ◽  
Coronary Insufficiency ◽  
Relaxant Effect ◽  
Ammi Visnaga ◽  
Long Time

Ammi visnaga L. (Visnaga daucoides Gaertn., Family Apiaceae), also known as Khella Baldi or toothpick weed, is an annual or biennial herb indigenous to the Mediterranean region of North Africa, Asia, and Europe. The plant is known to have been used in traditional medicine a long time ago. Nowadays, it is used in modern medicine to treat many aliments such as renal colic and coronary insufficiency, and is used as an antioxidant, antifungal, and antibacterial, with a larvicidal effect on mosquito larvae. Peer-reviewed studies show that these pharmacological activities are due its valuable chemical constituents that include mainly essential oil, polyphenolic compounds including flavonoids, as well as γ-pyrones, represented mainly by khellin and visnagin. Its essential oil is reported to have antiviral, antibacterial, and larvicidal effects, while its flavonoid content is responsible for its antioxidant activity. Its γ-pyrone content has a powerful effect on facilitating the passage of kidney stones and relieving renal colic, in addition to having a relaxant effect on smooth muscle including that of the coronary arteries. The current review represents the progress in research on A. visnaga in terms of either its chemistry or biological activities. This review represents scientific support material for the use of the plant by the pharmaceutical industry.

scholarly journals Chemotyping the Essential Oil in Different Rosemary (Rosmarinus officinalis L.) Plants grown in Kashmir Valley

2017 ◽  
Vol 14 (3) ◽  
pp. 1025-1031 ◽  
Author(s):  
Tawheed Amin ◽  
H. R. Naik ◽  
Syed Zameer Hussain
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Chemical Constituents ◽  
Rosmarinus Officinalis ◽  
Oil Yield ◽  
Kashmir Valley ◽  
Plant Samples ◽  
Rosmarinus Officinalis L ◽  
Essential Oil Yield

ABSTRACT: The Aim of the Present Study Was to Evaluate the Yield, Chemical Constituents and Determine the Chemotype of the Essential Oil Obtained from Different Rosemary Plants Growing in Different Accessions of Rosemary Fields. About four Plant Samples Were Analyzed for Essential Oil Yield and the Essential Oil Yield Varied from 0.88% To 1.2%. the Essential Oil Samples Were Further Analyzed by Gas Chromatography (GC) for the Purpose of Identification of Chemical Constituents Present in Them. It Was Contended from the Results That the Selected Plants Differed from Each Other in Terms of Chemical Constituents.Camphor Content Was Foundin Higher Amount in All the Foursamples, Thus it Could Be Inferred That the Plants Are Camphor Chemotype.

Efficiency of the optimized microwave assisted extractions on the yield, chemical composition and biological activities of Tunisian Rosmarinus officinalis L. essential oil

2017 ◽  
Vol 105 ◽  
pp. 224-233 ◽  
Author(s):  
Asma Farhat ◽  
Hasnia Benmoussa ◽  
Rafik Bachoual ◽  
Zina Nasfi ◽  
Walid Elfalleh ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Biological Activities ◽  
Rosmarinus Officinalis ◽  
Microwave Assisted ◽  
Rosmarinus Officinalis L

Phytochemical analysis of essential oil from Rosmarinus officinalis L. of Iran

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
F Nazari ◽  
S Shaabani ◽  
H Khiry
Keyword(s):  
Essential Oil ◽  
Rosmarinus Officinalis ◽  
Phytochemical Analysis ◽  
Rosmarinus Officinalis L

Biological Activities of Carlina Oxide Isolated from the Roots of Carthamus caeruleus

2020 ◽  
Vol 10 (2) ◽  
pp. 145-152 ◽  
Author(s):  
Imane Rihab Mami ◽  
Rania Belabbes ◽  
Mohammed El Amine Dib ◽  
Boufeldja Tabti ◽  
Jean Costa ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Essential Oil ◽  
Skin Diseases ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Penicillium Expansum ◽  
Natural Food ◽  
Antioxidant Power

Background: Carthamus caeruleus belongs to the Asteraceae family. The roots are traditionally used as healing agents. They help to heal burns and treat skin diseases. They are also used against joint inflammation and are very effective against diseases such as irritable bowel syndrome for cancer patients. Objectives: The purpose of this work was i) to study the chemical composition of i) the essential oil and hydrosol extract of Carthamus caeruleus, ii) to isolate the major component of both extracts and iii) to evaluate their antioxidant, antifungal and insecticidal activities. Methods: The essential oil and hydrosol extract obtained from the roots were studied by GC and GC/MS. The antioxidant activities were performed using two different methods i) Radical scavenging activity (DPPH) and ii) the Ferric-Reducing Antioxidant Power (FRAP), using BHT as a positive control. Whereas, the antifungal activity of the essential oil and Carlina oxide was investigated against plant fungi. The fumigation toxicity of C. caeruleus essential oil besides Carlina oxide was evaluated against adults of Bactrocera oleae better known as the olive fly. Results: The essential oil and hydrosol extract were mainly represented by acetylenic compounds such as carline oxide and 13-methoxy carline oxide. Carlina oxide was isolated and identified by 1H and 13C NMR spectroscopic means. The results showed that Carlina oxide presented interesting antioxidant and antifungal properties, while C. caeruleus root essential oil had better insecticidal activity. Furthermore, Carlina oxide has demonstrated promising in vivo antifungal activity to control infection of apples by Penicillium expansum. Conclusion: Carlina oxide can be used as a natural food preservative and alternative to chemical fungicides to protect stored apple against Penicillium expansum.

Quali-quantitative variation of essential oil from Iranian rosemary (Rosmarinus officinalis L.) accessions according to environmental factors

2017 ◽  
Vol 30 (1) ◽  
pp. 16-24 ◽  
Author(s):  
Iman Bajalan ◽  
Razieh Rouzbahani ◽  
Abdollah Ghasemi Pirbalouti ◽  
Filippo Maggi
Keyword(s):  
Environmental Factors ◽  
Essential Oil ◽  
Rosmarinus Officinalis ◽  
Quantitative Variation ◽  
Rosmarinus Officinalis L
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