Comparative clinical study of Alambushadi Churna and Dwipanchmuladya Tail Basti in the management of Amavata vis-a–vis Rheumatoid Arthritis

In Ayurvedic text book, Amavata symptom is mentioned as swelling, joint pain, numbness, appetite loss, indigestion and fever. In Charaka Samhita and Sushruta Samhita, Amavata is mentioned as a syndrome called Vatavyadhi, a diverse group of symptoms that are organized according to the systemic and local manifestations of Vata Dosha. According to the Charaka Samhita of Vatavyadhi, when Vata affects the Asthi and Majja there is painful swelling and immobility of the joints. Hence clinical study is planned to evaluate effect of Alambushadi Churna and in the Management of Amavata for that 60 Patients having classical symptomatology of Amavata have been selected from Kayachikitsa OPD and IPD of Sir Sunder Lal Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi and divided in two groups. Results of study shows that the sign and symptoms e.g., Loss of appetite, Angamarda, Alasya etc. due to derangement of Aam are observed to be improved in by Alambushadi Churna oral dose compared to Methotrexate.

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A prospective, randomized, double-blind, comparative clinical study of efficacy and safety of a biosimilar adalimumab with innovator product in patients with active rheumatoid arthritis on a stable dose of methotrexate

Indian Journal of Rheumatology ◽

10.4103/0973-3698.233164 ◽

2018 ◽

Vol 13 (2) ◽

pp. 84

Author(s):

Prasad Apsangikar ◽

Sunil Chaudhry ◽

Manoj Naik ◽

Shashank Deoghare ◽

Jamila Joseph

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Study ◽

Active Rheumatoid Arthritis ◽

Efficacy And Safety ◽

Double Blind ◽

Innovator Product ◽

Stable Dose ◽

Comparative Clinical Study

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A comparative clinical study of Amavatavidhwansa Rasa and Simhanaada Guggulu in the management of Amavata w.s.r. to Rheumatoid Arthritis

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.5.3.5 ◽

2020 ◽

Vol 5 (03) ◽

pp. 27-31

Author(s):

Vaibhav A. Jagadale ◽

M. Shrinivasarao ◽

G. Vinay Mohan ◽

Girish Dharmannavar ◽

M. B. Rudrapuri

Keyword(s):

Rheumatoid Arthritis ◽

Risk Factor ◽

Clinical Study ◽

Dietary Habits ◽

Medical Science ◽

Environmental Exposures ◽

Human Race ◽

Severe Morbidity ◽

Comparative Clinical Study

Amavata is the most challenging disease for the medical science, as it causes severe intolerable pain and severe deformities making the patient disable and bedridden. As it is the disease of Rasavaha Srotas and having several features similar to Rheumatoid Arthritis, Amavata can be correlated with Rheumatoid Arthritis (RA). Amavata is the outcome of Agnidushti, Amotpatti and Sandhivikrutti, with the passage of the time most of the dietary habits, changing lifestyle and environment have been contributing to the disease, the risk factor include age, gender, genetics and environmental exposures. Hence Amavata have became a challenge to the human race. Management of the disease is merely insufficient in other system of medicine, in such condition disease which continues to pose challenge to the physician as well as for patients due to severe morbidity and crippling nature. So patients are continuously looking for the treatment from Ayurved to overcome this challenge. It also shows extra articular features like bodyache, stiffness etc. many research have been carried out to solve this clinical enigma.The therapy which normalizes Agni metabolizes Ama and regulates Vata and maintain healthy Sandhi and Sandhistha Shelshma will be the supreme one for this disease. The formulations of Amavatavidhvansa Rasa and Simhanaada Guggula is indicated, especially in treating the Amavata.

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