scholarly journals An experimental study of the femoral nerve in the long-term periods after modeling lateral interbody spondylodesis of the lumbar spine

2021 ◽  
Author(s):  
Tatiana Varsegova ◽  
Olga Vladimirovna Diuriagina ◽  
Nikolai Ivanovich Antonov ◽  
Sergey Olegovich Ryabykh
Keyword(s):  
Lumbar Spine ◽  
Support Function ◽  
Surgical Intervention ◽  
Femoral Nerve ◽  
Fold Increase ◽  
Early Postoperative Period ◽  
Titanium Implants ◽  
Neurological Symptoms ◽  
Lateral Interbody

Neuropathies of the lumbar plexus trunks, in particular those of the femoral nerve, are the most common complications of lateral interbody spondylodesis of the lumbar spine. Modeling of this surgical intervention in normal animals experimentally makes it possible to assess the degree of its trauma to the nervous structures, and to understand what is the reason for the persistence or aggravation of neurological symptoms iatrogenic injuries or the existing pathology progression. Purpose of the Study. To study histological and morphometric changes in the femoral nerve in the long-term periods after modeling of the lateral interbody spondylodesis of the canine lumbar spine. Design of the Study. An experimental prospective continuous uncontrolled study. Material and Methods. Discectomy via lateral approach was performed in 18 mongrel dogs (aged 2-3 years, mass 13.2-17.6 kg) at the level of L4-5 и L5-6, interbody titanium implants were mounted, the lumbar spine was stabilized with a wire device for external fixation within 30 days. Clinical-and-neurological evaluation was performed, as well as histological investigation of the femoral nerves from the side of surgical approach. Results. In the early postoperative period a temporary decrease in the femoral nerve function was observed, which was manifested by the disorder of the support function and muscle weakness of the pelvic limbs, decrease in the knee reflex, the foot support shift to the metatarsal pad. Later, until the end of the study (18 months), the general condition of all animals was satisfactory, there were no disorders of the limb support function and motor reflexes. After six months, in the femoral nerve there was 4-fold decrease in the proportion of large fast-conducting myelin fibers D 10 m and 3-fold increase in that of the small ones. The mean axon diameter and myelin thickness were 62% and 53% of the norm. After 12-18 months, the dimensional characteristics of myelin fibers were restored. During the entire experiment, 4-6% of myelin fibers were reactively-and-destructively altered. Conclusions. The modeling of the lateral interbody spondylodesis of the lumbar spine in normal animals experimentally demonstrated the absence of neurological symptoms after 6-18 months, which indicated low invasiveness of the surgical intervention. Nevertheless, the subclinical reactive-and-destructive changes in the myelin fibers of the femoral nerve revealed 6 months after the surgery indicated the need for preventive anti-neurotic therapy.

Cervical juxtafacet cyst after anterior cervical discectomy and fusion

2011 ◽  
Vol 31 (4) ◽  
pp. E19 ◽  
Author(s):  
Walavan Sivakumar ◽  
J. Bradley Elder ◽  
Mark H. Bilsky
Keyword(s):  
Neck Pain ◽  
Surgical Intervention ◽  
Neurological Symptoms ◽  
Anterior Cervical Discectomy ◽  
Long Term Outcomes ◽  
Motor Weakness ◽  
Neurosurgical Procedure ◽  
Cervical Discectomy ◽  
Juxtafacet Cyst

Anterior cervical discectomy and fusion (ACDF) is a common neurosurgical procedure, and the benefits, long-term outcomes, and complications are well described in the literature. The development of a juxtafacet joint cyst resulting in radiculopathy is a rare outcome after ACDF and merits further description. The authors describe a patient in whom a juxtafacet joint cyst developed after ACDF procedures, resulting in surgical intervention. When a juxtafacet joint cyst develops after ACDF, symptoms can include radiculopathy, neck pain, and neurological symptoms such as paresthesias and motor weakness. The presence of a juxtafacet joint cyst implies instability in that region of the spine. Patients with this pathological entity may require decompression of neural elements and fusion across the segment involved with the cyst.

scholarly journals ПРОГНОЗУВАННЯ ПЕРЕБІГУ ТА РЕЗУЛЬТАТУ ЛІКУВАННЯ ІНВАГІНАЦІЇ КИШЕЧНИКА У ДІТЕЙ

2015 ◽  
Author(s):  
S. V. Veselyi ◽  
M. Yu. Veselyi
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Postoperative Period ◽  
Surgical Intervention ◽  
Late Complications ◽  
Early Postoperative Period ◽  
Intestinal Fistulas ◽  
Long Term Observation ◽  
Morphological Research

The catamnesis in 150 children with an intussusception in terms from 6 months till 10 years after surgical intervention is investigated. Complex biochemical and immunological inspection is carried out to 30 patients. Besides morphological research 10 bioptats of the taken parietal peritoneum, is carried out during operative treatment. Studying before-, intra-and postoperative condition of patients, and also forecasting of current and outcome of disease carried out as a result of search of the «risk factors» determining probability of occurrence and gravity of clinical current of the invagination of intestine in children. In the early postoperative period 4 children (2.7 %) have died in connection with an incompetence of the anastomosis, plural intestinal fistulas and progressing of the peritonitis. Catamnesis observation has revealed, that 104 (69.3 %) the child after operative desinvagination grew and developed according to age. 34 patients (22.7 %) further had the gastroenteropathy described periodic dysphagia and dyspepsia by the phenomena. In 12 children (8.0 %) the adhesive disease has developed. Patients with high risk of occurrence of late complications after operative desinvagination require long-term observation and rehabilitation actions.

scholarly journals RADICAL LUNG RESECTION IN TREATMENT OF PULMONARY TUBERCULOSIS

2017 ◽  
Vol 2 (2) ◽  
pp. 56-59
Author(s):  
PV V Rogozhkin ◽  
EA A Borodulina
Keyword(s):  
Surgical Treatment ◽  
Surgical Intervention ◽  
Lung Resection ◽  
Early Postoperative Period ◽  
First Year ◽  
Drug Resistant ◽  
Reactivation Process ◽  
Acute Condition

Aim - to analyze afterhistory of TB patients who had radical lung resection. Methods of research. On the basis of the results of surgical treatment of 273 patients in 2010-2011, two groups were formed: the first group - patients who were deregistered due to their recovery; the second group -patients who had tuberculous process reactivated after surgery as recurrence or acute condition. Results. The effectiveness of tuberculosis surgical treatment in long-term period was proved in more than 90% of cases. Reactivation process started in 7.7% of cases, in patients who had multiple and extensive drug resistant MTB (53.3%), in patients who had destruction in the lung tissue (62%); in patients with fibrous-cavernous tuberculosis (33.3%), with comorbidity (52.4%), with complications in the early postoperative period (9.5%). Reactivation occurred more often in cases of wide surgical intervention, including cases with follow-up remedial thoracoplasty. If there are indications for surgical treatment, it is better to decide upon surgery within the first year of supervision.

Presentation, surgical intervention, and long-term survival in patients with Marfan syndrome

2020 ◽  
Vol 72 (2) ◽  
pp. 480-489
Author(s):  
Nathan J. Aranson ◽  
Priya B. Patel ◽  
Jahan Mohebali ◽  
Robert T. Lancaster ◽  
Emel A. Ergul ◽  
...  
Keyword(s):  
Marfan Syndrome ◽  
Surgical Intervention ◽  
Term Survival ◽  
Long Term Survival

scholarly journals The Long-Term Follow-Up of Patients with Cystine Stones: A Single-Center Experience for 13 Years

2021 ◽  
Vol 10 (7) ◽  
pp. 1336
Author(s):  
Toshifumi Takahashi ◽  
Shinya Somiya ◽  
Katsuhiro Ito ◽  
Toru Kanno ◽  
Yoshihito Higashi ◽  
...  
Keyword(s):  
Surgical Intervention ◽  
Median Number ◽  
Small Sample ◽  
Age At Diagnosis ◽  
Surgical Interventions ◽  
Significant Difference ◽  
Long Term Follow Up ◽  
Cystine Stones

Introduction: Cystine stone development is relatively uncommon among patients with urolithiasis, and most studies have reported only on small sample sizes and short follow-up periods. We evaluated clinical courses and treatment outcomes of patients with cystine stones with long-term follow-up at our center. Methods: We retrospectively analyzed 22 patients diagnosed with cystine stones between January 1989 and May 2019. Results: The median follow-up was 160 (range 6–340) months, and the median patient age at diagnosis was 46 (range 12–82) years. All patients underwent surgical interventions at the first visit (4 extracorporeal shockwave lithotripsy, 5 ureteroscopy, and 13 percutaneous nephrolithotripsy). The median number of stone events and surgical interventions per year was 0.45 (range 0–2.6) and 0.19 (range 0–1.3) after initial surgical intervention. The median time to stone events and surgical intervention was 2 years and 3.25 years, respectively. There was a significant difference in time to stone events and second surgical intervention when patients were divided at 50 years of age at diagnosis (p = 0.02, 0.04, respectively). Conclusions: Only age at a diagnosis under 50 was significantly associated with recurrent stone events and intervention. Adequate follow-up and treatment are needed to manage patients with cystine stones safely.

scholarly journals Long-term postoperative opioid prescription after cholecystectomy or gastric by-pass surgery: a retrospective observational study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Viktoria Larsson ◽  
Cecilia Nordenson ◽  
Pontus Karling
Keyword(s):  
Observational Study ◽  
Postoperative Period ◽  
Medical Records ◽  
Early Postoperative Period ◽  
Retrospective Observational Study ◽  
Opioid Use ◽  
Opioid Prescription ◽  
Post Surgery ◽  
Gastric By Pass

Abstract Objectives Opioids are commonly prescribed post-surgery. We investigated the proportion of patients who were prescribed any opioids 6–12 months after two common surgeries – laparoscopic cholecystectomy and gastric by-pass (GBP) surgery. A secondary aim was to examine risk factors prior to surgery associated with the prescription of any opioids after surgery. Methods We performed a retrospective observational study on data from medical records from patients who underwent cholecystectomy (n=297) or GBP (n=93) in 2018 in the Region of Västerbotten, Sweden. Data on prescriptions for opioids and other drugs were collected from the patients` medical records. Results There were 109 patients (28%) who were prescribed opioids after discharge from surgery but only 20 patients (5%) who still received opioid prescriptions 6–12 months after surgery. All 20 of these patients had also been prescribed opioids within three months before surgery, most commonly for back and joint pain. Only 1 out of 56 patients who were prescribed opioids preoperatively due to gallbladder pain still received prescriptions for opioids 6–12 months after surgery. Although opioid use in the early postoperative period was more common among patients who underwent cholecystectomy, the patients who underwent GBP were more prone to be “long-term” users of opioids. In the patients who were prescribed opioids within three months prior to surgery, 8 out of 13 patients who underwent GBP and 12 of the 96 patients who underwent cholecystectomy were still prescribed opioids 6–12 months after surgery (OR 11.2; 95% CI 3.1–39.9, p=0,0002). Affective disorders were common among “long-term” users of opioids and prior benzodiazepine and amitriptyline use were significantly associated with “long-term” opioid use. Conclusions The proportion of patients that used opioids 6–12 months after cholecystectomy or GBP was low. Patients with preoperative opioid-use experienced a significantly higher risk of “long-term” opioid use when undergoing GBP compared to cholecystectomy. The indication for being prescribed opioids in the “long-term” were mostly unrelated to surgery. No patient who was naïve to opioids prior surgery was prescribed opioids 6–12 months after surgery. Although opioids are commonly prescribed in the preoperative and in the early postoperative period to patients with gallbladder disease, there is a low risk that these prescriptions will lead to long-term opioid use. The reasons for being prescribed opioids in the long-term are often due to causes not related to surgery.

scholarly journals No Observed Adverse Effects on Health Were Detected in Adult Beagle Dogs When Fed a High-Calcium Diet for 40 Weeks

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1799
Author(s):  
Jujhar Atwal ◽  
Jonathan Stockman ◽  
Matthew Gilham ◽  
David Allaway ◽  
Helen Renfrew ◽  
...  
Keyword(s):  
Filtration Rate ◽  
Fold Increase ◽  
Diet Group ◽  
Test Diet ◽  
Beagle Dogs ◽  
Adverse Health Effects ◽  
Mineral Balance ◽  
High Calcium ◽  
High Calcium Diet

The implications of long-term high calcium (Ca) intake are well documented in growing dogs and in adult dogs of large breed size, however, the consequences on other breeds and breed sizes are yet to be determined. Eighteen neutered adult beagles, nine males and nine females aged 1.4–4.4 years, were randomized to control or test diets providing in g∙4184 kJ−1 (1000 kcal−1): 1.44 and 7.19 total Ca balanced with 1.05 and 4.25 total phosphorus, respectively, for 40 weeks. Health parameters, ultrasound scans, radiographs, glomerular filtration rate, and mineral balance were measured at eight-week intervals. All dogs remained healthy with no measured evidence of orthopedic, urinary, or renal disease. The test diet resulted in a 5.2 fold increase in fecal Ca excretion. Apparent Ca digestibility (%) and Ca balance (g/d) did not significantly (p > 0.05) change from baseline in the test diet group, although dogs displayed a positive Ca balance (maximum at week 8, 1.11 g/d with 95% CI (0.41, 1.80)) before a neutral Ca balance was restored at week 32. Despite an initial positive Ca balance, we can conclude that no measurable adverse health effects were observed as a result of the test diet fed in this study in beagles over a period of 40 weeks.

scholarly journals Incisional hernia after extreme lateral interbody fusion on the lumbar spine: A case report

2021 ◽  
Vol 78 ◽  
pp. 130-132
Author(s):  
Masakazu Wakabayashi ◽  
Yurika Miyazaki ◽  
Kana Aoki ◽  
Hayato Yoshida ◽  
Kou Minoshima ◽  
...  
Keyword(s):  
Case Report ◽  
Lumbar Spine ◽  
Incisional Hernia ◽  
Interbody Fusion ◽  
Lateral Interbody Fusion ◽  
Extreme Lateral Interbody Fusion ◽  
Lateral Interbody
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