scholarly journals ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB) IN CREAM AGAINST PROPIONIBACTERIUM ACNES

Author(s):  
SYAHRIDA DIAN ARDHANY ◽  
SUSI NOVARYATIIN

Objective: The aims of this present study were to formulate antiacne cream consisting ethanolic extract of bawang dayak and evaluate antibacterialactivity of cream on day 0 and day 7 to see stability activity and preparation.Methods: Cream formula of bawang dayak was evaluated organoleptic characteristics, homogeneity, pH, adhesion test, dispersion test, and in vitroantibacterial against Propionibacterium acnes.Results: The results of evaluate cream homogeneity were F3 and F4 on day 7 separate and non-homogen but all formula pH suitable for topicalapplication. On day 0, F1 and F2 shown antibacterial activity in category weak activity, F3 and F4 in category moderate activity, while on day 7 allformula have antibacterial activity in category weak activity.Conclusion: All cream formula potentials inhibit against P. acnes but this research must be improved both of preparation and stability activity.

2019 ◽  
Vol 2 (2) ◽  
pp. 121-126
Author(s):  
Syahrida Dian Ardhany ◽  
Yunari Puspitasari ◽  
Yuyun Meydawati ◽  
Susi Novaryatiin

Bawang dayak (Eleutherine bulbosa (Mill.)urb) is one of plants of Central Kalimantan. Empirically, Bawang dayak is used to treat skin problems, one of them is acne vulgaris, so that it is necessary to test the inhibition of ethanolic extract of Bawang Dayak against acne causing such as P.acnes.  In the pharmaceutical world there is still no research conducted on the manufacture of antiacne cream contain ethanolic extract of Bawang Dayak bulbs, so the researchers conducted it to improve the efficiency of the use of traditional medicine. The results of phytochemical screening showed that ethanolic extract of bawang dayak contained flavonoid, alkaloid, saponin, tanin and catechol with the inhibition zone classified as moderate activity at the concentration of 1% and weak activity at other concentrations (5%, 10% and 15%). Based on the evalution of cream preparations the results of the organoleptic test for antuacne cream have a dark brown color and distinctive odor, homogen for homogeneity test, adhesion test and dispersion test according to the requirements and the pH observation showed ph (6) suitable for topical application. Based on these results, the evaluation antiacne cream fulfills the physical test, but it needs to be developed further for stability and effectiveness of antiacne cream against the bacteria acnes causing.   


Author(s):  
SYAHRIDA DIAN ARDHANY

Objective: The aim of the present study was to investigate phytochemical screenings and the in vitro effect antibacterial of BD (Eleutherine Sp.) and TU (Ampelocissus Sp.) against Propionibacterium acnes.Methods: The antibacterial activity was investigated against Propionibacterium acnes by well diffusion method.Results: Preliminary phytochemical screenings of BD ethanolic extract were found positive alkaloid, saponin, tannins, and steroid while TUpositive flavonoid, saponin, tannins, steroid, and triterpenoid. Antibacterial activity against Propionibacterium acnes of ethanolic extract BD with concentration 25 mg/ml and 50 mg/ml showed the zone of inhibition 3.23 mm and 7.8 mm with category weak activity while ethanolic extract TU with same concentration showed zone of inhibition 10 mm (weak activity) and 16.3 mm (moderate activity) which mean ethanolic extract TU have better antibacterial activity. A combination ethanolic extract of both with variant ratio showed a zone of inhibition 6.7 mm (1:1), 3.9 mm (1:2), and 3.63 mm (2:1).Conclusion: In this present study showed the highest potential antibacterial activity against propionibacterium acnes is an ethanolic extract of TU and The best ratio combination is 1:1. Furthermore, this study needs more research with variant concentration so that may be possible to be used as natural anti-acne formulations.


Author(s):  
Semwal Amit Negi Sweta

Abstract-Medicinal plants represent an essential source of drugs and have played an important role in healthcaresystem.PyracanthacrenulataandZanthoxylum armatumhave been used as traditional medicine. The main aim of the study was to find the antibacterial activity of the selected plants against bacterialspecies:E.coliandPseudomonasaeruginosa. The solvents used for plant extraction were hexane, chloroform, ethanol and aqueous. The in vitro antimicrobial activity was performed by Agar disk diffusion method. The hexane and aqueous extracts showed moderate activity whereas theethanolicextractsshowedasignificantantibacterial activity. In the study Tetracycline was used as standard. The combined ethanolic extract of both the selected plant showed the synergistic effect on the bacterial strain tested. This leads to the conclusion that the combined effect can have possible application in the development of products as antimicrobial.


2021 ◽  
Vol 5 (4) ◽  
pp. 375-380
Author(s):  
Ayu Nala El Muna Haerussana ◽  
Wulan Putri Dwiastuti ◽  
Cindi Arwan Sukowati

Indonesia has a high diversity of potential medicinal plants, which are the second-largest number of indigenous medicinal plants in the world. Syzygium polyanthum, known as Indonesian Bay Leaf or Salam, easily found, widely used in Indonesia as a spice in cooking and traditional medicine. Salam contains secondary metabolites such as flavonoids, alkaloids, tannins, essential oils, sesquiterpenes, triterpenes, phenols, steroids, and saponins. Staphylococcus aureus and Staphylococcus epidermidis are the main bacteria that cause commensal infection and the most common nosocomial infections. This study aims to know the antibacterial activity of the Salam ethanolic extract against Staphylococcus aureusand Staphylococcus epidermidis bacteria. Salam leaves were extracted by 70% ethanol in the maceration method. Antibacterial activity was conducted by the disk diffusion method. The extract exhibits moderate activity (10.51±0.3 mm) at 75% of concentration and low activity (3.69±0.4 mm) at 100% of concentration against Staphylococcus aureus and Staphylococcus epidermidis respectively. The test showed that salam leaves extract had antibacterial activity against Staphylococcus aureus and Staphylococcus epidermidis.


INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (04) ◽  
pp. 53-55
Author(s):  
G.P Vadnere ◽  
◽  
A.R. Pathan ◽  
B.U Kulkarni ◽  
A.K. Singhai

Ethanolic extract of leaf, flower and root of Plumbago zeylenica L. (white variety) traditionally used in the treatment of gastrointestinal disorders were screened for antibacterial activity against bacterial pathogens Staphyllococcus aureus, Escerchia coli, Klebsiella pneumoniae, Enterobacter aurugens, Proteus vulgaris, Shigella sonnei, Salmonella typhi which are known to cause different type of gastrointestinal disorders. The results showed that leaf and root extracts exhibited strong antibacterial action at concentration of 2-8 mg/ mL of the bacterial pathogen tested. However, powdered flower extract showed moderate activity. Thus the present data reveals that leaves and flowers are equally potential for the treatment of bacterial pathogens, which causes intestinal catarrh, indigestion, and colic intestinal abscesses.


Author(s):  
Hams H. H. Alfattli ◽  
Ghufran Zuhair Jiber ◽  
Ghaidaa Gatea Abbass

This study which designed to evaluate the inhibitory effect of Ethanolic extract of (Quercusrobur) and Zinc oxide nanoparticles on the growth of one genus of enterobacteriacae (Salmonella). In vitro. For this purpose graduate concentrates for plant extract (50, 100, 200, 400 )mg/ml which prepared and compared with Zinc oxide nanoparticles of different concentration (2, 1, 0.5, 0.25) μg/ml,and examined. The result showed that the studied medicinal plant has antibacterial activity against this bacteria which used. The result showed that the plant has good activity in decrease the growth of this bacteria. The results of the study also showed that the nano-ZnO has very effective antibacterial action against the studied bacteria which was Salmonella,nanoparticles concentrations lead to increasing in the inhibition zones of tested bacterial growth. We also study the effect of three antibiotics Lomefloxacin (LOM), Ciprofloxacin (SIP) and Rifampin (RA) and the result showed,in a comparison within the tested bacteria,Salmonella had a significant inhibition increase in Lomefloxacin ; the ciprofloxacin showed effect on tested bacteria. However,Rifampin does not show any effect on tested bacteria.


2018 ◽  
pp. 1
Author(s):  
اشواق طالب الرجب ◽  
نضال ابراهيم لطيف ◽  
هند يونس خلف

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