Auto-PEEP effects on respiratory mechanics and blood gases in mechanically ventilated patients

1998 ◽  
Vol 74 (4) ◽  
pp. 275-83
Author(s):  
Antônio C. P. Ferreira ◽  
Benjamin I. Kopelman ◽  
Werther Brunow de Carvalho ◽  
Jorge Bonassa
Keyword(s):  
Respiratory Mechanics ◽  
Blood Gases ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Ventilated Patients

Respiratory mechanics in mechanically ventilated patients with respiratory failure

1985 ◽  
Vol 58 (6) ◽  
pp. 1849-1858 ◽  
Author(s):  
A. Rossi ◽  
S. B. Gottfried ◽  
B. D. Higgs ◽  
L. Zocchi ◽  
A. Grassino ◽  
...  
Keyword(s):  
Time Constant ◽  
Inflation Rate ◽  
Respiratory Mechanics ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Airway Occlusion ◽  
The Relationship ◽  
Resistance Value ◽  
Ventilated Patients

In 11 mechanically ventilated patients, respiratory mechanics were measured 1) during constant flow inflation and 2) following end-inflation airway occlusion, as proposed in model analysis (J. Appl. Physiol. 58: 1840–1848, 1985. During the latter part of inflation, the relationship between driving pressure and lung volume change was linear, allowing determination of static respiratory elastance (Ers) and resistance (RT). The latter represents in each patient the maximum resistance value that can obtain with the prevailing time constant inhomogeneity. Following occlusion, Ers and RT were also obtained along with RT (min) which represents a minimum, i.e., resistance value that would obtain in the absence of time constant inhomogeneity. A discrepancy between inflation and occlusion Ers and RT was found only in the three patients without positive end-expiratory pressure, and could be attributed to recruitment of lung units during inflation. In all instances Ers and RT were higher than normal. RT(min) was lower in all patients than the corresponding values of RT, indicating that resistance was frequency dependent due to time constant inequalities. Changes in inflation rate did not affect Ers, while RT increased with increasing flow.

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