scholarly journals Systematic Review of Plants Used Against Respiratory Diseases Related to COVID-19 in Africa

2021 ◽  
Vol 11 (4-S) ◽  
pp. 141-153
Author(s):  
Gabriel A Agbor ◽  
Rosette Ndjib

Background: Respiratory disorders are known to affect the airways including the nasal passages, bronchi and lungs causing blockages. The advent of COVID-19 has further aggravated the complications of the respiratory systems where conventional medicine is not reachable or affordable by the majority poor in Africa. Hence, the over 80% of the African population who turn to traditional medicine for their primary health care. Objective: This review is aimed to identify plants directed against respiratory diseases which can be useful in the fight against COVID-19. Methodology: Scientific articles selected in this study span the last ten years (2011-2021). Keywords such as “ethnobotany in Africa”, “ethnobotany and respiratory diseases” “medicinal plants and respiratory diseases”, “traditional medicine and COVID-19” were searched in open access search engines such as: Science Direct, Research Gate, Google Scholar, Pubmed, Web of Science, Scopus. The ethnobotanical indices were then calculated using Microsoft excel to determine the plants with the most therapeutic potential to be considered for the local management of COVID-19. Results: Data obtained were classified according to country of origin of the author of the publication, the botanical family and the respiratory pathology being treated. Thirteen (13) references were finally selected with the represented country being Benin Republic. One hundred and forty-three plant species belonging to 60 families were registered. The most recurrent families were the Fabaceae and Lamiaceae (18 citations each). The plants in these families were used for the management of fifteen diseases and / or symptoms relating to the respiratory system. The most cited plants were: Ocimum gratissimum L. (4 citations), Entandrophragma cylindrium (Sprague), Scyphocephalium ochocoa Warb., Rubia cordifolia and Allium sativum L. (3 citations each). Conclusion: Based on the data obtained in this review Ocimum gratissimum stands out as the most used plant for the treatment of respiratory disorders. Keywords: Respiratory diseases, Medicinal plants, COVID-19

2021 ◽  
Author(s):  
Helena Correia ◽  
Maria Wanda Emanuelson ◽  
Moisés Nhantumbo ◽  
Paulo Andrassone ◽  
Graça Cumbi ◽  
...  

Abstract Background Epilepsy is a chronic brain disease that affects about 50 million people worldwide, mainly in developing countries. It is treated with anticonvulsant drugs, but in some cases, conventional anticonvulsants have not been effective, leading patients to turn to alternative herbal treatments. The study aimed to identify plants used in traditional medicine for the treatment of epilepsy in southern Mozambique, record the parts used, the method of preparation as well as the mode of administration. Methodology: The study was conducted between April to June 2019. 53 Traditional Medicine Practitioners were interviewed using a semi-structured questionnaire. The data was analyzed by calculating the Percentage of Citation (%FC) and Informant Factor Consensus (IFC). Results A total of 32 medicinal plants belonging to 18 botanical families were identified for the treatment of epilepsy in the southern part of Mozambique. The species, Hugonia orientalis Engl (22.64%), Maclura africana Bur (16.98%), Strychnos spinosa Lam (13.21%), Terminalia sericea Bruch ex DC (13.21%) and Manilkara mochisia (Bark) Dubard (11.32%) were the most cited. The families Annonaceae and Menispermaceae (4 species) were the most representative in number of species. The root was the most commonly used plant part (54.2%), the frequently used preparation mode was decoction (71%), and administration of the remedies was often by oral route. Conclusion Medicinal plants still play an important role in primary health care in the study area. However there is a need to develop pharmacological studies based on these plants to understand the mechanism of action of the bioactive compounds and for the future development of new and more effective anticonvulsant drugs


Author(s):  
KAMRAN ASHRAF

Nowadays, the use of medicinal plants increased significantly for the aim of producing more effective drugs with fewer side effects. Gynura procumbens (family Asteraceae) is a high value medicinal plant with different properties that are considered less, regardless of having great therapeutic potential in traditional medicine. Many pharmacological studies have established the ability of this plant to exhibit antimicrobial, antioxidant, hepatoprotection, antigenotoxic, antiplasmodial, cytotoxic, cardioactive, antidiabetic, anti-inflammatory, etc. The aim of this study was to review the updated phytochemical, pharmacological investigations as well as the traditional and therapeutic uses of G. procumbens. Important and different experimental data have been addressed along with a review of most of the phytochemicals identified in this plant.


2020 ◽  
Vol 14 (8) ◽  
pp. 2837-2853
Author(s):  
Stéphane Effoe ◽  
Efui Holaly Gbekley ◽  
Mamatchi Mélila ◽  
Amégninou Aban ◽  
Tchadjobo Tchacondo ◽  
...  

Les plantes alimentaires contiennent des principes actifs doués de diverses propriétés médicinales pouvant intervenir dans le traitement de nombreuses maladies. Cette étude est consacrée au recensement des plantes ayant des potentiels nutritionnel et thérapeutique dans la région Maritime du Togo, dans le but de la valorisation de ces plantes. De juin à septembre 2017, une enquête ethnobotanique, basée sur l’utilisation des interviews individuelles à l'aide d'un questionnaire semi-structuré, a été réalisée auprès de 101 Praticiens de la Médecine Traditionnelle. Au total 86 espèces végétales appartenant à 72 genres et 36 familles ont été identifiées. Les Fabaceae et les Solanaceae (7 espèces chacune) ont été les plus représentées. Les espèces les plus citées ont été Ocimum gratissimum L. (10,48%), Vernonia amygdalina Delile (6,71%), Lactuca taraxacifolia (Willd.) Schum. (6,08%) et Heliotropium indicum L. (5,66%). Les feuilles (77,85%), les fruits (5,63%) et les racines (4,26%) sont les organes les plus utilisées sur 799 recettes inventoriées. La principale forme galénique reste la sauce (51,19%) et le mode principal d’administration est la voie orale (90,74%). Concernant les maladies traitées, les affections du tube digestif sont au premier rang (43,80%) suivies par des affections cardiovasculaires (13,52%). Cette étude fournie une base de données sur des plantes ayant des potentiels nutritionnel et thérapeutique au Togo.Mots clés : Alicaments, potentiels nutritionnel et thérapeutique, sécurité alimentaire, Togo.   English title: Ethnobotanical study of some food plants used in traditional medicine in the Maritime region of TogoFood plants contain active substances with various medicinal properties that can be used to treat many diseases. This study is devoted to the inventory of plants with nutritional and therapeutic potential in Maritime region of Togo, with the aim of promoting these plants. From June to September 2017, an ethnobotanical survey was conducted among 101 Traditional Medicine Practitioners through individual interviews using a semi-structured questionnaire. A total of 86 plants species belonging to 72 genera and 36 families were identified. Fabaceae and Solanaceae (7 species each) were the most represented. The most cited species were Ocimum gratissimum L. (10.48%), Vernonia amygdalina Delile (6.71%), Lactuca taraxacifolia (Willd.) Schum. (6.08%) and Heliotropium indicum L. (5.66%). The leaves (77.85%), fruits (5.63%) and roots (4.26%) were the most plant parts used out of 799 inventoried recipes. The main dosage form remains the sauce (51.19%) and the main mode of administration is the oral route (90.74%). Regarding the treated diseases, the digestive disorders are in first place (43.80%), followed by cardiovascular diseases (13.52%). This study provides a database of plants with nutritional and therapeutic potential in Togo.Keywords: Food plants, nutritional and therapeutic potentials, food security, Togo.


Author(s):  
Tawseef Ahmad Mir ◽  
Rakesh Kumar Khare ◽  
Muatasim Jan

People are using medicinal plants to alleviate diseases since the time immemorial. The present paper enumerates a total of 25 medicinal plants belonging to 19 families used for the treatment of diarrhoea and dysentery diseases in Khag tehsil of district Budgam, Jammu and Kashmir. Asteraceae was the dominant family. Leaves were found to be dominant plant used for the preparation of herbal remedies. It was found that in this era of modern medicine, people are still relied on traditional medicine to get their primary health care. It was also revealed medicinal plants are under serious threat and needs to be conserved as so as to enjoy this legacy in future too.


Author(s):  
Dipsundar Sahu ◽  
Shakti Bhushan ◽  
Debajyoti Das ◽  
Saroj Kumar Debnath ◽  
Laxmidhar Barik ◽  
...  

In herbal medicine, there is a substantial amount of variety of plants have been used to treat neurodegenerative disorders including Alzheimer's (AD)as well as other memory-related issues. Dementia is a neurological condition characterised by a progressive loss in emotional and cognitive abilities. Dementia is linked to a number of conditions like inadequate cerebral blood flow, poison toxicity, and other risk factors and conditions mitochondrial dysfunction, oxidative injury, and, in certain cases coexistence with other diseases like Alzheimer's disease (AD), Huntington's disease, Parkinson's syndrome (PD) and Attention Deficit Hyperactivity Disorder (ADHD).Despite the fact that there are well-established semi-synthetic medications for the treatment of AD and AD-related dementia, the majority of them have a number of side effects. As a result, conventional medicine offers a variety of plant-derived lead molecules that may be valuable in future medical studies. In this paper, we look at how ayurvedic plants are used to treat neurodegenerative disease around the world. Plants are also neuroprotective against proinflammatory cytokines including IL-6, IL-1b, TNF-a and it was reported that Antioxidant activity was increased, oxidant levels were reduced, and acetylcholinesterase activity was inhibited in the nervous system by these medicinal plants. We've highlighted the most essential ayurvedic medicinal plants as well as their biochemical effects. As a result, the effects of the above medicinals plants and their active constituents strengthened neurodegenerative conditions, indicating their therapeutic potential in ailments like Alzheimer's disease. and depression that are linked to neuroinflammation and neurotransmitter dysfunction.


Author(s):  
Ebimobowei Assayomo ◽  
Dorcas Dauta Bawo ◽  
Ayodele Oyedeji ◽  
Gloria Ekpatarziba Ezenatein ◽  
Ahiakwo Bright Ogbo

Aims: This study investigated the level of zinc, nickel, lead and cadmium in selected medicinal plants - Scent Leaf (Ocimum gratissimum) and Pawpaw (Carica papaya) that are traditionally used in alternative medicine in Amassoma community, Bayelsa State, Nigeria. Study Design: Scent leaf (Ocimum gratissimum) and Pawpaw (Carica papaya) from where these plants are grown were randomly collected for heavy metal analysis from within Amassoma community in Southern Ijaw Local Government Area of Bayelsa State, Nigeria Place and Duration of Study: This study was carried out in Biological Sciences, Faculty of Science, Niger Delta University, Wilberforce Island, Amassoma, Bayelsa State between March 2019 to September 2019 Methodology:  Scent leaf (Ocimum gratissimum) and Pawpaw (Carica papaya) were digested and analyzed for heavy metals using Atomic Absorption Spectrophotometer (AAS, model S471096). The method used was wet-ashing method for the analysis. Results: The result showed that the concentration of Lead in the pawpaw fruit with 5.99mg/kg and pawpaw seed with 3.72mg/kg, were above the WHO permissible limit. While the concentration of Cadmium in the pawpaw fruit, pawpaw leaf, pawpaw seed and scent leaf with 1.32mg/kg, 0.96mg/kg, 0.21mg/kg, and 0.59mg/kg, were all above the permissible limits. Again, Zinc in the pawpaw fruit, pawpaw leaf, pawpaw seed and scent leaf were 2.52mg/kg, 2.53mg/kg, 5.30mg/kg, and 0.79mg/kg respectively, and these are also above the permissible limit. While that of the concentration of Nickel in the pawpaw fruit, pawpaw leaf, pawpaw seed and scent leaf were observed to be within permissible limit. Conclusion: It is therefore recommended that caution should be taken when such plants are to be used as alternative to conventional medicine as excess of it could pose the risk of bioaccumulation and possible health effects in humans.


Plants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2038
Author(s):  
Ebenezer Kwabena Frimpong ◽  
John Awungnjia Asong ◽  
Adeyemi Oladapo Aremu

The use of medicinal plants in the management of diverse ailments is entrenched in the culture of indigenous people in African communities. This review provides a critical appraisal of the ethnobotanical uses of medicinal plants for the management of headache in Africa. Research articles published from 2010 (Jan) to 2021 (July) with keywords such as Africa, ethnobotany, headache, medicinal plant and traditional medicine were assessed for eligibility based on sets of pre-defined criteria. A total of 117 plants, representing 56 families, were documented from the 87 eligible studies. Asteraceae (10%), Fabaceae (10%), Lamiaceae (9%) and Mimosaceae (5%) were the most represented plant families. The most popular plant species used in the management of headache were Ocimum gratissimum L. (n = 7), Allium sativum L. (n = 3), Ricinus communis L. (n = 3) and Artemisia afra Jack. ex. Wild (n = 2). The leaves (49%), roots (20%) and bark (12%) were the most common plant parts used. Decoction (40%) and infusion (16%) were the preferred methods of preparation, whereas the oral route (52%) was the most preferred route of administration. The data revealed that medicinal plants continue to play vital roles in the management of headache in African communities. In an attempt to fully explore the benefits from the therapeutic potential of indigenous flora for common ailments, further studies are essential to generate empirical evidence on their efficacies, using appropriate test systems/models. This approach may assist with the ongoing drive towards the integration of African traditional medicine within mainstream healthcare systems.


2021 ◽  
Vol 4 (1) ◽  
pp. 588-605
Author(s):  
Carlos Rocha Oliveira ◽  
Vitor Di Luca Junges Cal ◽  
Dayane Ferreira Vaz ◽  
Patrícia Barbosa Fialho ◽  
Rafaela Santana Curiele ◽  
...  

This review aimed to describe some plants used in Brazilian folk medicine in respiratory disorders, highlighting species not well known to the Brazilian citizens. The articles were surveyed in the MEDLINE / PubMed, Web of Science, SCOPUS / Elsevier, SciELO and Cochrane with the descriptors in Health Sciences (DeCS) databases: Medicinal plants, herbal medicine and respiratory diseases with the keywords: secondary metabolites and pulmonary disorders, considering the period from June 2010 to June 2020. The results indicated that species known as Mikania glomerata and Allium sativum, are well studied, presenting a large volume of publications and results on phytochemical and pharmacological aspects. In contrast, lesser-known species of the Brazilian population, such as Amburana cearensis, Hybanthus ipecacuanha, and Jatropha curcas, need more studies, which explore their potential in the medical field. Brazilian biodiversity offers a wide variety of medicinal plants, some of which are better known and studied; others less known and little studied, requiring further investigation in order to provide a scientific basis, both for the isolation and synthesis of molecules and for possible therapeutic applications in different respiratory diseases.


2020 ◽  
Author(s):  
James Kiamba Mailu ◽  
Joseph Mwanzia Nguta ◽  
James Mucunu Mbaria ◽  
Mitchel Otieno Okumu

Abstract Background Respiratory diseases cause many deaths in children under 5 years of age particularly in Africa. The efficacy of current treatment differs among respiratory diseases and adverse effects may depend on dosage, duration of treatment, and the type of drug. Poor access to healthcare in rural areas makes many people in such communities to rely on traditional medicine. Most knowledge on traditional medicine makes use of indigenous remedies which are often undocumented and are at risk of being lost. Ethnobotanical data on medicinal plants used in managing diseases of the respiratory system may facilitate the search for new pharmaceutical agents. Methods Semi-structured questionnaires were used to collect information from 30 traditional medicine practitioners in Kisumu East Sub County. The sociodemographic characteristics of the informants, the local names of the plants used, their habit, active parts, indications, and methods of preparation, as well as routes of administration, scientific identity, and conservation status were recorded. A literature search was conducted via PubMed, Google Scholar, and Research Gate to identify other reported activities of the plants. Results Most practitioners were female (86.7%), were aged between 61 and 70 years (43.3%), had no formal education (56.7%), and had 21-30 years of practice (30%). A total of 45 plant species, belonging to 43 genera and 28 families were identified. Leguminosae and Rutaceae were the most dominant plant families, leaves were the most frequently used (33%), and trees were the most common habit (44.4%). Cough was the most common indication, decoction was the most common method of administration (68.8%), most preparations were taken orally, and most plants were collected in the wild (79.2%). Literature search established that at least 42/45 plant species had pharmacological activities. Conclusions Many plant species reported in this study have similar traditional uses in other communities. One plant; Keetia gueinzii (Sond.) Bridson was reported for the first time in the management of asthma, pneumonia, and cough. Documentation and preservation of ethno medicinal knowledge in the study area is of prime concern as most practitioners are advanced in age with little formal education. Plans to conserve some of the medicinal plants documented here should be initiated. Scientific validation of the traditional claims made is also needed.


Author(s):  
ArunakumarN C and Ranjith Y

Fundamental screening of phytochemicals is a significant advance, in the location of the bioactive standards present in restorative plants and therefore may prompt medication disclosure and improvement. In the current examination, chief phytoconstituents of the six chose restorative plants of various families were distinguished so as to relate their essence with bioactivities of the plants.Screening of six chose therapeutic plants was performed for the presence of tannins, flavonoids, terpenoids, saponins, steroids, phlobatannins, starches, glycosides, coumarins, alkaloids, proteins, emodins, anthraquinones, anthocyanins and leucoanthocyanins utilizing standard strategies.All the chose restorative plants were found to contain tannins and flavonoids. In addition, terpenoids were additionally present in all the chose plants aside from P. dactylifera. but P. dactylifera. Then again, saponins and steroids were missing in all plants aside from S. chirata and phlobatannins were missing in all plants aside from R. sativus. Likewise, starches, glycosides and coumarins were available in all the chose plants aside from P. dactylifera and R. sativus. Alkaloids were available in all the chose plants aside from F. religiosa, P. dactylifera and R. sativus. Proteins were available just in F. religiosa and S. chirata. Though emodins, anthraquinones, anthocyanins and leucoanthocyanins were missing in all the chose six plants.It is evident from the study that S. chirata is of highest therapeutic efficacy possessing majority of phytochemical classes of compounds and P. dactylifera is of lowest therapeutic potential due to the absence of majority of phytoconstituents.


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