scholarly journals Post-Traumatic Tracheal Stenosis: Results of Tracheal Reconstruction: A Multicenter Case Series

2021 ◽  
Vol 5 (2) ◽  
Keyword(s):  
Tracheal Stenosis ◽  
Case Series ◽  
Long Term Results ◽  
Tracheal Reconstruction ◽  
Reconstruction Methods ◽  
Number Of Patients ◽  
Case Series Study ◽  
Post Traumatic ◽  
Grade 3 ◽  
Post Intubation

Objectives: to find out the long-term results of tracheal reconstruction in terms of presentation, operation, complications, and outcomes of tracheal reconstruction. Methods: In this case-series study, the patients who developed post-intubation tracheal stenosis following respiratory failure were followed up for two years for the possible complications. The patients were diagnosed by experienced pulmonologist in two surgical centers, Erbil and Sulaimaniya in Iraqi Kurdistan in 2017. Results: The number of patients who were included in this study was 20; including males (n=13) and females (n=7) ranged between 18-58 years. The causes of the stenosis in patients were post-intubation (n=18) and post-tracheostomy for trauma (n=5). Most patients underwent extubation after 72 hours. The Myer-Cotton Grade of stenosis were grade 1 (n=1), grade 2 (n=13), and grade 3 (n=6). The major complications were dehiscence (n=3) and anastomotic edema (n=5). The minor complications were granulation (n=13) and mild anastomotic edema (n=1). One patient developed a surgical site infection and one patient developed a mild infection. The anastomotic fibrin deposition was developed in five patients. All patients had excellent satisfaction except for two patients (unsatisfactory). One of these patients died at month 1. The patients had normal medical conditions at different times of follow-ups. Conclusions: This study showed that the results of the patients with post-traumatic tracheal stenosis were acceptable at different times for most of them.

scholarly journals Safety and efficacy of posterior iris claw intraocular lens fixation in aphakic patients

2018 ◽  
Vol 16 (2) ◽  
pp. 124-133
Author(s):  
Rosemary Tomy ◽  
Rajkumar Maheshwari ◽  
Ansa Parveen Kunhu Muhammed ◽  
Venkataramana Kalikivayi ◽  
Sajeev Cherian Jacob
Keyword(s):  
Intraocular Lens ◽  
Anterior Segment ◽  
Case Series ◽  
Visual Outcome ◽  
Applanation Tonometry ◽  
Long Term Results ◽  
Retrospective Case ◽  
Case Series Study ◽  
Wide Range

Purpose: To assess the indications and visual outcome of eyes undergoing posterior iris fixated intraocular lens (IFIOL) implantation for aphakia, to identify reasons for poor visual outcome, and report occurrence of complications. Methods: In this retrospective case series study, all cases of posterior IFIOL fixation performed over a 30-month period were identified retrospectively. Preoperative and postoperative evaluations comprised objective and subjective refraction, best corrected visual acuity (BCVA), slit lamp biomicroscopy, applanation tonometry, and dilated fundus examination. Results: Fifty-six eyes of 56 patients were analyzed. Mean age was 60.55 ± 17.2 years. The most common indication for IFIOL implantation was surgical aphakia following complicated cataract surgery (n = 33; 58.9%) followed by trauma (n = 10; 17.9%), dropped nucleus/IOL during primary surgery (n = 6; 10.7%), and subluxated/dislocated lens-induced glaucomas (n = 5; 8.9%). BCVA better than or equal to their preoperative BCVA was achieved in 96.43% patients. The surgical aphakia and paediatric/adolescent groups had the best visual results while the dropped nucleus/IOL group and subluxated lens-induced glaucoma groups fared poorly. On the long-term follow-up visit, the most common complication noted was pigment dusting on the corneal endothelium (65.7%). Conclusion: The long-term results suggest that posterior IFIOL implantation is a safe and effective method for correction of aphakia and can be used for a wide range of indications in eyes without adequate capsule support. It may be considered an easier and faster alternative with minimal manipulation to anterior segment structures in paediatric and post-traumatic aphakic eyes.

scholarly journals Frequency of Mortality in Patients with Post-Partum Eclampsia-A Study at Liaquat University Hospital, Hyderabad, Sindh, India

2019 ◽  
Vol 7 (03) ◽  
Author(s):  
Almas Almas ◽  
Naushaba Rizwan ◽  
Syed Farhan Uddin
Keyword(s):  
Post Partum ◽  
Case Series ◽  
University Hospital ◽  
Study Patient ◽  
Inclusion Criteria ◽  
Risks And Benefits ◽  
Number Of Patients ◽  
Case Series Study ◽  
Patient Will ◽  
Series Study

Postpartum preeclampsia is the occurrence of hypertension and proteinuria after delivery. Preeclampsia plus seizures after delivery is defined as postpartum eclampsia. Objective: To determine the frequency of mortality in patients with post-partum eclampsia; To determine the obstetrical factors leading to maternal mortality in patient with postpartum eclampsia. Methodology: The descriptive case series study was carried out in the department of Department of obstetrics and gynecology LUMHS Hospital Hyderabad from 1st January 2018 to 30 June 2018. All patients who fulfilled the inclusion criteria were included in the study. Informed consent was taken after explaining the procedure, risks and benefits of the study. All patients of postpartum eclampsia with increase blood pressure and proteinuria admitted through out-patient department or emergency within 48 hours of delivery will be included in the study. Patient will be followed for 10 days. All the collected data were entered into the proforma attached at the end. Results: Mean ± SD of age was 27.88±7.77 with C.I (27.02…….28.74) years. Mean ± SD of systolic B.P and urine protein was 161.46±22.09 mmhg and 1432.59±967.33 mg respectively. Out of 369 was occurred mortality in 190 (60%) women. Conclusion: It is to be concluded that mortality is most in eclampctic women followed by patients with Pre-eclampsia. However a study design comprising multiple centers, and a higher number of patients over a longer period of time will be more representative.

scholarly journals The Therapeutic Effects of Goreisan, a Traditional Japanese Herbal Medicine, on Lower-Limb Lymphedema after Lymphadenectomy in Gynecologic Malignancies: A Case Series Study

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Nobuhisa Yoshikawa ◽  
Hiroaki Kajiyama ◽  
Naoki Otsuka ◽  
Satoshi Tamauchi ◽  
Yoshiki Ikeda ◽  
...  
Keyword(s):  
Lower Limb ◽  
Gynecologic Cancer ◽  
Case Series ◽  
Patient Characteristics ◽  
Pelvic Lymphadenectomy ◽  
Whole Body ◽  
Therapeutic Effects ◽  
Retroperitoneal Lymphadenectomy ◽  
Number Of Patients ◽  
Case Series Study

Background. Lower-limb lymphedema (LLL) is a chronic and progressive complication of gynecologic cancer treatment, including pelvic lymphadenectomy. This study aims to investigate the therapeutic effect of goreisan, a traditional Japanese medicine, which has been used for hydrostatic modulation on patients with LLL. Methods. Patients diagnosed with LLL in our hospital in 2018 were included and principally treated with complex decongestive therapy (CDT), including elastic clothing and lymph drainage. The patients who received a combination therapy of CDT and goreisan (CDT-G group) were prescribed goreisan extract granules, with a dose of 7.5 g per os daily in three doses. Patients who were not prescribed goreisan received CDT alone (CDT group). The severity of lymphedema was evaluated by the estimated limb volume calculated by limb circumferences and the ratio of extracellular water (ECW) to total body water (TBW). Results. Nineteen women with LLL after pelvic lymphadenectomy were included in the study. The number of patients in the CDT and CDT-G groups was 8 and 11, respectively. There were no statistically significant differences between the CDT and CDT-G groups in terms of patient characteristics and severity of LLL before treatment. Reduction in ECW/TBW in the CDT-G group (in the whole body and the affected lower limb) after the intervention was significantly more remarkable than that in the CDT group. Conclusions. Goreisan-based Japanese herbal therapy may be effective in patients with LLL after retroperitoneal lymphadenectomy.

The Role Of Shunt In The Norwood Procedure

2021 ◽  
Author(s):  
Nihat Çine ◽  
Fatih Yiğit ◽  
Ergin Arslanoğlu ◽  
Hakan Ceyran
Keyword(s):  
Right Ventricle ◽  
Clinical Outcomes ◽  
Case Series ◽  
Early Mortality ◽  
Long Term Results ◽  
Single Center ◽  
Case Series Study ◽  
Series Study

Objectives: In this study we observed that the effect of post-Norwood 3.5 mm modified BTS(mBTS and 5 mm right ventricle to pulmonary (Sano modification) shunt models on clinical outcomes. Patients and Methods: 54 patients who were operated in our hospital between 2011and 2020 years, were included in our study and this is a retrospective, observational, single-center case series study. Results: The effect of shunt type on mortality was statistically significant, and the rate of death was lower in patients who used SANO type shunts. (p <0.05) The effect of VISC score on early mortality was significant, and VISC score was higher in the group with exitus. (p <0.05). Conclusion: Although Sano shunt seems more preferred in Norwood, the experience of the surgeon and the center's experience may have led to variation in results at HLHS. Nevertheless, it will be clinically important for studies to evaluate the long-term results between the two shunt types.

Long-term results of bronchoscopic cryotherapy for post-intubation tracheal stenosis

2018 ◽  
Author(s):  
Evangelos Balis ◽  
Konstantinos Kotsifas ◽  
Nikolaos Tatsis ◽  
Angeliki Papanikolaou ◽  
Stavroula Boulia ◽  
...  
Keyword(s):  
Tracheal Stenosis ◽  
Long Term Results ◽  
Post Intubation

scholarly journals Tracheal resection with end-to-end anastomosis for post-intubation cervical tracheal stenosis: study of 14 cases

2011 ◽  
Vol 125 (9) ◽  
pp. 958-961 ◽  
Author(s):  
R Nandakumar ◽  
C Jagdish ◽  
C B Prathibha ◽  
C Shilpa ◽  
V Sreenivas ◽  
...  
Keyword(s):  
Tracheal Stenosis ◽  
Relevant Literature ◽  
Long Term Results ◽  
Definitive Treatment ◽  
Tracheal Resection ◽  
Airway Patency ◽  
End To End ◽  
Cervical Trachea ◽  
Post Intubation

AbstractBackground and objectives:The incidence of acquired laryngeal stenosis is increasing. This retrospective study aimed to assess the long term results of circumferential resection with end-to-end tracheal anastomosis for isolated post-intubation stenosis of the cervical trachea, and to review the relevant literature.Methods:Twelve male and two female patients (aged 16–30 years, mean age 24 years) treated between February 2003 and December 2008 were included. Hospital and office records were reviewed and relevant surgical details recorded.Results:Indications for tracheal resection anastomosis were post-intubation stenosis (78.57 per cent) and trauma (21.42 per cent). One to five tracheal rings were resected (i.e. 1–2.5 cm of cervical trachea). Tracheal anastomosis was considered successful if the patient remained asymptomatic for 24 months of close follow up (involving regular flexible bronchoscopy and neck X-ray). The anastomotic success rate was 92.85 per cent.Conclusion:Tracheal resection and end-to-end anastomosis is relatively safe and reliable for definitive treatment of benign tracheal stenosis in appropriate patients. Local application of mitomycin C prevents granulation and aids long term airway patency.

scholarly journals Adverse drug reactions in SARS-CoV-2 hospitalised patients: a case-series with a focus on drug–drug interactions

2020 ◽  
Author(s):  
Giada Crescioli ◽  
Valentina Brilli ◽  
Cecilia Lanzi ◽  
Andrea Burgalassi ◽  
Alessandra Ieri ◽  
...  
Keyword(s):  
Adverse Drug Reactions ◽  
Case Series ◽  
University Hospital ◽  
Drug Reactions ◽  
Case Evaluation ◽  
Hospitalised Patients ◽  
Number Of Patients ◽  
Case Series Study ◽  
Caucasian Patients ◽  
Series Study

AbstractDue to the need of early and emergency effective treatments for COVID-19, less attention may have been paid to their safety during the global emergency. In addition, characteristics of drug–drug interaction (DDI)-related adverse drug reactions (ADRs) in COVID-19 patients have not yet been studied in depth. The aim of the present case-series study is to describe clinical and pharmacological characteristics of SARS-CoV-2 hospitalised patients, focusing on ADRs, particularly those related to DDIs. We evaluated all reports of COVID-19 medication-related ADRs collected within the COVID-19 Units of Careggi University Hospital, Florence (Italy), between January 1st and 31st May 2020. Information regarding COVID-19 medications, patients’ demographic and clinical characteristics, concomitant drugs, ADRs description and outcome, were collected. Each case was evaluated for the causality assessment and to identify the presence of DDIs. During the study period, 23 Caucasian patients (56.5% males, mean age 76.1 years) experienced one or more ADRs. The majority of them were exposed to polypharmacy and 17.4% presented comorbidities. ADRs were referred to cardiovascular, psychiatric and gastrointestinal disorders. The most frequently reported preferred term was QT prolongation (mean QT interval 496.1 ms). ADRs improved or resolved completely in 60.8% of cases. For all patients, a case-by-case evaluation revealed the presence of one or more DDIs, especially those related to pharmacokinetic interactions. Despite the small number of patients, our evidence underline the clinical burden of DDIs in SARS-CoV-2 hospitalised patients and the risk of unexpected and uncommon psychiatric ADRs.

scholarly journals CPAP after endoscopic procedures as add-on therapy for the treatment of tracheal stenosis: a case series

2019 ◽  
Vol 89 (3) ◽  
Author(s):  
Adriano Gesuele ◽  
Simone Gambazza ◽  
Marta Lazzeri ◽  
Serena Conforti
Keyword(s):  
Tracheal Stenosis ◽  
Positive Airway Pressure ◽  
Positive Impact ◽  
Case Series ◽  
Long Term Results ◽  
Tracheal Resection ◽  
Endoscopic Procedures ◽  
Frequent Relapses

Tracheal stenosis represents a possible complication in intubated or tracheotomised patients. Tracheal resection is currently the gold standard for the treatment of complex stenosis while granulomas and simple stenosis (e.g., web-like) are often treated by endoscopic procedures, which do not consistently give satisfactory long-term results, due to frequent relapses. Administering continuous positive airway pressure (CPAP) after endoscopic procedures might represent a new add-on option for the treatment of this complication. In this case series are presented two patients with tracheal stenosis showed after the removal of tracheostomy tube, both treated with CPAP. The results were straightforward: CPAP treatment helped to keep stable the tracheal lumen, without adverse effects. No further endoscopic dilations were necessary thereafter, with a likely positive impact on patients’ quality of life and on health expenditure.

scholarly journals Equine Assisted Therapy for Patients with Post Traumatic Stress Disorder: A Case Series Study

2019 ◽  
Vol 184 (9-10) ◽  
pp. 394-399 ◽  
Author(s):  
Assaf Shelef ◽  
Dorit Brafman ◽  
Thom Rosing ◽  
Abraham Weizman ◽  
Rafael Stryjer ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Case Series ◽  
Post Traumatic Stress ◽  
Case Series Study ◽  
Open Case ◽  
Post Traumatic ◽  
Equine Assisted ◽  
Series Study

Abstract Introduction Equine assisted therapy (EAT) which includes therapeutic horseback riding (THR), grooming, horsemanship and ground level work with horses, has been studied as treatment for children with special needs and/or autistic spectrum disorder. Preliminary evidence indicates that EAT is also effective for improving self-efficacy and self-esteem in adults with psychiatric disorders. Empowerment, bonding and building trust with the horses, may promote functioning of patients struggling with post traumatic stress disorder (PTSD). The authors performed a prospective, pilot open case series study to assess the effect of EAT on patients with PTSD in terms of symptoms and functioning in work, family and social interaction. Methods Patients with PTSD received EAT once a week for 3 consecutive hours for 6 months. The Short Post Traumatic Stress Disorder Rating Interview (SPRINT) and the Sheehan Disability Scale (SDS) were assessed at baseline, the SDS after 1 and 6 months, and the SPRINT after 6 months. Results Thirteen of 23 participants completed the study. Ten participants withdrew from the study for various reasons including discomfort from horses. Total SPRINT scores showed a statistically significant improvement in PTSD symptoms (baseline vs. 6 months: 24.38 ± 6.4 vs. 21.54 ± 7.94 points; p &lt; 0.05). SPRINT scores indicated improvement in the ability to work and perform daily tasks (p &lt; 0.05). A statistically significant improvement in the total SDS score was revealed following 1 month (p &lt; 0.03) and after 6 months (p &lt; 0.02) of EAT. There was also a significant decline in the days of inefficiency (baseline vs. 6 months: 4.15 ± 2.73 vs, 1.88 ± 2.18 days per week, p &lt; 0.02). Conclusion This preliminary pilot open case series study suggests that EAT may be a beneficial treatment for patients suffering from PTSD. The study demonstrated improved ability to work and perform daily tasks and reduction in the number of days of inefficiency. Further large-scale long-term studies are warranted to substantiate our observation.

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