scholarly journals Colorectal Cancer in Patient with Functional Gastrointestinal Symptoms

2022 ◽  
Vol 31 (5) ◽  
pp. 66-73
Author(s):  
Z. A. Mamieva ◽  
E. A. Poluektova ◽  
A. L. Kovaleva ◽  
O. S. Shifrin ◽  
V. P. Sobolev ◽  
...  
Keyword(s):  
Rectal Adenocarcinoma ◽  
Clinical Manifestations ◽  
Gastrointestinal Symptoms ◽  
Abdominal Ultrasound ◽  
Gastrointestinal Diseases ◽  
Detailed Examination ◽  
Key Points ◽  
Irritable Bowel ◽  
Functional Gastrointestinal Diseases ◽  
Russian Association

Aim. A clinical observation to highlight the importance of detailed examination in patients with functional gastrointestinal symptoms.Key points. A 28-yo female patient was admitted with complains of left ileal pain, abdominal distention and up to 4-day stool delay. The complaints had long been interpreted as clinical manifestations of irritable bowel syndrome. No significant abnormalities were revealed in outpatient check-up (general and biochemical blood panels, stool test, abdominal ultrasound, oesophagogastroduodenoscopy). Colonoscopy was performed on admission, with diagnosis of rectal adenocarcinoma. The patient had a prompt surgical intervention, repeated courses of polychemotherapy and is currently followed by an oncologist and coloproctologist. No relapse signs have been reported.Conclusion. Patients with the complaints satisfying the Rome Criteria Revision IV for functional gastrointestinal diseases should have a thorough examination as per recommendations of the Russian Gastroenterological Association and Russian Association of Coloproctologists. 

scholarly journals Current Prospects of Herbal STW 5 Agent in Treatment of Functional Gastrointestinal Diseases

2022 ◽  
Vol 31 (5) ◽  
pp. 61-65
Author(s):  
A. A. Sheptulin
Keyword(s):  
Irritable Bowel Syndrome ◽  
Functional Dyspepsia ◽  
Treatment Efficacy ◽  
Gastrointestinal Diseases ◽  
Mechanisms Of Action ◽  
Current Evidence ◽  
Key Points ◽  
Irritable Bowel ◽  
Functional Gastrointestinal Diseases ◽  
Agent Development

Aim. A review of current therapeutic perspectives of the herbal STW 5 medicine (Iberogast®) in functional gastrointestinal (GI) diseases.Key points. A limited remediation in most common functional GI diseases, functional dyspepsia (FD) and irritable bowel syndrome (IBS), is conditioned by their multifactorial pathogenesis. Meanwhile, most specific medicines only target selected pathogenesis components, thus warranting a multitarget agent development. Such is Iberogast® that acts at variant components of FD and IBS pathogenesis. The article reviews the Iberogast® mechanisms of action and evaluates its treatment efficacy in FD and IBS.Conclusion. The current evidence claims that Iberogast® provides an effective and safe treatment for FD and IBS. 

scholarly journals FRACTURES OF THE MANDIBLE AT THE BODY AND ANGLE REGION: PATTERNS, EPIDEMIOLOGY, DIAGNOSTIC PRINCIPLES. PART I

2017 ◽  
Vol 21 (2) ◽  
pp. 100-103
Author(s):  
Sh. Chzhan ◽  
P. S Petruk ◽  
Yu. A Medvedev
Keyword(s):  
Successful Treatment ◽  
Imaging Techniques ◽  
Clinical Manifestations ◽  
Detailed Examination ◽  
Accurate Diagnosis ◽  
The Body ◽  
Mandibular Fractures ◽  
Relevant Today ◽  
Treatment And Prevention ◽  
Key Points

The article reflects the aspects of epidemiology and principles of diagnosis in mandibular fractures. The problem remains relevant today. Due to the complexity of the mechanisms of the injury and their acceptance, a variety of clinical manifestations, the limited knowledge of the patients about their injury, the diagnosis and treatment of these injuries sometimes are difficult. Detailed examination with modern imaging techniques and accurate diagnosis are the key points in successful treatment and prevention of complications in this category of patients.

scholarly journals Diarrhea syndrome: new accents of patient curation during COVID-19 pandemic

2021 ◽  
Vol 5 (6) ◽  
pp. 446-452
Author(s):  
O.V. Gaus ◽  
◽  
M.A. Livzan ◽  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Ischemic Colitis ◽  
Clinical Manifestations ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Disorder ◽  
Infected People ◽  
Antibiotic Associated Diarrhea ◽  
Irritable Bowel ◽  
Diarrhea Syndrome ◽  
Post Infectious

The digestive tract, like the respiratory organs, is the entrance gate for SARS-CoV-2. At the same time, diarrhea is one of the most common gastrointestinal symptoms among infected people. As the debut of COVID-19 clinical manifestations, diarrhea can be associated both with the direct cytopathic effect of the virus on the intestinal mucosal epithelium and with the gut microbiota modulation. During the period of the expanded clinical picture of COVID-19, diarrhea syndrome is commonly associated with the adverse event of drug therapy, primarily antibiotics, nonsteroidal anti-inflammatory drugs, antiviral agents, antiplatelet agents and anticoagulants, as well as with possible involvement in the pathological process of the liver and pancreas with a violation of their functional activity. Finally, after the infection, the repeated occurrence of diarrhea requires the exclusion of antibiotic-associated diarrhea, including those caused by Clostridium difficile, as well as ischemic colitis and post-infectious irritable bowel syndrome. Besides, despite the pandemic, it should not be forgotten about the possible debut of gastrointestinal disorder or an exacerbation of already existing chronic pathology. The article presents a brief algorithm for the differential diagnosis of diarrhea in the conditions of the COVID-19 pandemic. KEYWORDS: diarrhea, COVID-19 pandemic, antibiotic-associated diarrhea, ischemic colitis, post-infectious irritable bowel syndrome. FOR CITATION: Gaus O.V., Livzan M.A. Diarrhea syndrome: new accents of patient curation during COVID-19 pandemic. Russian Medical Inquiry. 2021;5(6):446–452 (in Russ.). DOI: 10.32364/2587-6821-2021-5-6-446-452.

scholarly journals Correlation Between the Brain-Gut Axis Mechanism and Functional Gastrointestinal Diseases from the Perspective of Chinese Medicine

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Li Yang
Keyword(s):  
Chinese Medicine ◽  
Psychological Factors ◽  
Gastrointestinal Disease ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Diseases ◽  
Gastrointestinal Illness ◽  
Digestive Diseases ◽  
New Ideas ◽  
The Brain ◽  
Functional Gastrointestinal Diseases

In recent years, with the increasing pressure of life and work, the number of people suffering from anxiety disorders and depression is increasing. In addition to the manifestations of depressed mood, depressed will, slow thinking and so on, most of them are accompanied by more obvious gastrointestinal symptoms. More and more studies have proved that psycho-psychological factors are one of the primary triggers of the onset of digestive diseases. The proposed mechanism of the brain-gut axis can not only explore the pathogenesis of gastrointestinal illness from the psychological level but also provide new ideas for the treatment related to gastrointestinal disease caused by psychological factors.

Functional gastrointestinal diseases

2018 ◽  
Author(s):  
Satish Keshav ◽  
Alexandra Kent
Keyword(s):  
Abdominal Pain ◽  
Gastrointestinal Diseases ◽  
Chronic Abdominal Pain ◽  
Bowel Habit ◽  
Functional Bowel Disorder ◽  
Functional Abdominal Pain ◽  
Biliary Pain ◽  
Irritable Bowel ◽  
Functional Gastrointestinal Diseases ◽  
Bowel Disorder

Irritable bowel syndrome is a functional bowel disorder characterized by chronic abdominal pain associated with a change in bowel habit or stool consistency in the absence of any definite organic abnormality. It is the commonest functional gastrointestinal syndrome. Many others have been defined clinically, including functional dyspepsia, functional biliary pain, functional abdominal pain, and so on.

scholarly journals An Integrated Gut Microbiota and Network Pharmacology Study on Fuzi-Lizhong Pill for Treating Diarrhea-Predominant Irritable Bowel Syndrome

2021 ◽  
Vol 12 ◽  
Author(s):  
Zhang Zhen ◽  
Lin Xia ◽  
Huang You ◽  
Zhou Jingwei ◽  
Yang Shasha ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gut Microbiota ◽  
Clinical Effect ◽  
Gastrointestinal Diseases ◽  
The Body ◽  
Network Pharmacology ◽  
Ifn Γ ◽  
Irritable Bowel ◽  
D Model ◽  
Functional Gastrointestinal Diseases

Diarrhea-predominant irritable bowel syndrome (IBS-D) is one of the most common chronic functional gastrointestinal diseases with limited treatments. Gut microbiota play an important role in chronic gastrointestinal diseases. In traditional Chinese medicine (TCM), Spleen–Yang deficiency (SYD) is one of the root causes of IBS-D. Fuzi-Lizhong pill (FLZP) is well known for its powerful capacity for treating SYD and has a good clinical effect on IBS-D. However, the mechanism of FLZP on the gut microbiota of IBS-D has not been fully clarified. Our present study aimed to reveal the mechanism of FLZP regulating gut microbiota of IBS-D. The body mass, CCK, MTL, and Bristol fecal character score were used to verify the establishment of the IBS-D model. IL-6, TNF, IL-1β, and IFN-γ were crucial targets screened by network pharmacology and preliminarily verified by ELISA. Eighteen gut microbiota were important for the treatment of IBS-D with FLZP. Bacteroidetes, Blautia, Turicibacter, and Ruminococcus_torques_group were the crucial gut microbiota that FLZP inhibits persistent systemic inflammation in the IBS-D model. Lactobacillus is the crucial gut microbiota that FLZP renovates intestinal immune barrier in the IBS-D model. In summary, FLZP can affect bacterial diversity and community structures in the host and regulate inflammation and immune system to treat IBS-D.

Probiotics in gastroenterology – from a different angle

2013 ◽  
Vol 154 (8) ◽  
pp. 294-304 ◽  
Author(s):  
György Miklós Buzás
Keyword(s):  
Side Effects ◽  
Beneficial Effect ◽  
Analytical Data ◽  
Well Being ◽  
Gastrointestinal Diseases ◽  
Convincing Evidence ◽  
Probiotic Treatment ◽  
History Of ◽  
Irritable Bowel

After a short overview of the history of probiotics, the author presents the development of human intestinal microflora based on the newest genetic data and the microbiological features of main probiotics. The indications of probiotic administration have been defined and extended in recent years. The author reviews significant results of probiotic treatment in some gastrointestinal diseases based on meta-analytical data. Probiotics are useful in preventing and treating diarrhoea caused by antibiotics and Clostridium difficile caused diarrhoea. In the treatment of Helicobacter pylori infection, preparations containing certain Lactobacillus,Bifidobacterium strains or Saccaromyces boulardii could enhance by 5–10% the rate of successful eradication and reduce the incidence and severity of the side effects. Some symptoms of irritable bowel syndrome and thus the quality of life can be improved by probiotics. Their beneficial effect in ulcerative colitis was proven, while in Crohn’s disease has not yet been defined. The use of probiotics is not included in guidelines, with the exception of the Maastricht IV/Florence consensus. For each disease it is advisable to use probiotics containing strains only with proven beneficial effect. The efficiency of preparations containing mixed strains has not yet been properly investigated. The author reviews the rare but potentially serious side effects of probiotics. In Hungary, there are many probiotic preparations available which can be purchased in pharmacies without prescription: their use is more empirical than evidence-based. The European Food Safety Authority has recently rejected claims for probiotics to be classed as medicines given the lack of convincing evidence on the effects of probiotics on human health and well-being. Clearly, further research is needed to collect evidence which could be incorporated into the international guidelines. Orv. Hetil., 2013, 154, 294–304.

Sign in / Sign up

Export Citation Format

Share Document