scholarly journals The correlation between lifestyle and lipid profile

2006 ◽  
Vol 59 (1-2) ◽  
pp. 57-62
Author(s):  
Bosa Mirjanic-Azaric ◽  
Mirjana Djeric ◽  
Maja Vrhovac ◽  
Dusanka Sukalo
Keyword(s):  
Physical Activity ◽  
Alcohol Consumption ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Hdl Cholesterol ◽  
Unhealthy Lifestyle ◽  
Lifestyle Habits ◽  
Cholesterol Ratio ◽  
Insufficient Physical Activity ◽  
The Mean

Introduction. The aim of this study was to estimate if negative lifestyle habits such as alcohol consumption, smoking and physical inactivity affect the lipid profile values. Material and methods. The study included 250 workers on regular examination in the Gradiska Health Center in the period from 2001 to 2002. There were 113 (45.2%) men and 137 (54.8%) women. The examinees were divided into three groups according age (25-39, 40-49 and 50-60 respectively). Standard laboratory methods were used to establish the following: total cholesterol, triglyceride and HDL-cholesterol level, LDL cholesterol, atherosclerosis index (AI) and total cholesterol/HDL cholesterol. Results Using a questionnaire, we have found out that out of 250 examinees 48.80% consume alcohol regularly, 50.80% are smokers and 36% are physically. The mean total cholesterol was high in all groups and it was 6.41 mmol/l. The mean triglyceride level was 1.88 mmol/l and mean HDL cholesterol was 1.48 mmol/l, I A was 2.99 and total cholesterol/HDL cholesterol ratio was 4.69. Statistical analysis showed that there was a statistically significant relationship between triglyceride values and alcohol consumption, smoking and physical activity (p<0.05). Also, we showed that there was a statistically high relationship between HDL cholesterol values, AJ, total cholesterol/HDL cholesterol and smoking in the examined groups (p<0.01). Discussion In our study the lipid profile parameters were above the desired levels, probably due to unhealthy lifestyle, including smoking, alcohol consumption and insufficient physical activity. Our results are in concordance with the results of similar studies. Conclusion It is of utmost importance to take steps to improve lifestyle habits of our population.

scholarly journals Deranged Serum Fasting Lipid Profile in Children and Adolescent with Thalassemia Major

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 4899-4899 ◽  
Author(s):  
Sadia Sultan ◽  
Syed Mohammed Irfan ◽  
Rozina Zeeshan
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Serum Ferritin ◽  
Total Lipid ◽  
Ldl Cholesterol ◽  
Hematological Parameters ◽  
Hdl Cholesterol ◽  
Thalassemia Major ◽  
Cholesterol Ratio ◽  
The Mean

Abstract Introduction: Serum fasting lipid profile has been studied in various clinical spectrum of β-thalassemia syndrome. Premature cardiac impairment in thalassemia major (TM) appears primarily due to iron accumulation and oxidative injury; however it might be a sequel of abnormal lipoprotein concentrations. Recent studies revealed impaired lipid profile and atherosclerosis in TM as an emerging complication in patients with prolonged survival. As these children are at risk of premature atherosclerosis, sub clinical atherosclerosis probably begins early in their life might evolve into coronary heart diseases in later life. The rational of this prospective cross sectional study is to analyze the serum fasting lipid profile in cardiovascular disease free thalassemia major patients and to establish any correlation with age, gender, hematological parameters, liver enzymes and serum ferritin. Method: The study group comprises of thirty six patients with β-thalassemia major, who were enrolled from March 2012 to March 2014. Fasting blood lipid levels (total lipid, cholesterol, triglycerides, HDL and LDL-cholesterol), liver function test and serum ferritin were measured in all study participants on Hitachi 912 through photometric assay (for lipid profile and liver function test) and by immunoturbidity methodology for serumferritin. Hematological parameters were determined by Cell Dyne Ruby (Abbot, Architect, USA). Patients were stratified in two groups, age ≤ 15 years and >15 years, to determine the possible lipid profile distinction in relation to increasing age. Results: Of the 36 patients, 17 were males (15.5±5.9 years) and 19 were females (10.1±4.5 years) with the mean age of 12.69±5.85 (range 5-24) years. Mean hemoglobin was 7.4±1.9gm/dl with the hematocrit of 23.1±5.7% while serum ferritin was markedly elevated 4699.7±3089ng/ml. The mean total lipid, cholesterol and triglycerides levels were 494.7 ± 114.5, 90.3 ±23.9 and 150.5±95.1 mg/dl respectively. High triglycerides were detected in 36.1%. While HDL cholesterol and LDL cholesterol were markedly low 17.7±9.2 and 42.3±22.0 mg/dl respectively. The mean total cholesterol to HDL ratio was significantly elevated, 6.21± 3.06 (normal <5.0). In addition, total-cholesterol to HDL-cholesterol ratios were increased irrespective of gender, that is 6.0±2.0 and 6.4± 3.8 in males and females respectively (P=0.6). Data analysis revealed that 22.2% females and 13.8% males had high triglyceride levels (P=0.05). No statistically significant difference was noted in two stratified age groups in respect to lipid profile (table-1). We established positive correlation of elevated total bilirubin with cholesterol, HDL and LDL cholesterol (P<0.05). Cholesterol ratio was also significantly high in patients with hemoglobin > 8gm/dl (P<0.05). Low HDL cholesterol was correlated positively with LDL cholesterol levels. While no significant correlation of serum lipid could be established with age, gender, high ferritins and with liver enzymes. Conclusion: Our study revealed that lipid profile impairment is not unusual in β-thalassemia major patients irrespective of age. Considerable deficiency of high density cholesterol and significantly high total-cholesterol to HDL-cholesterol ratio may strongly be associated with occurrence of coronary heart disease in later life. We propose that lipid profile should be regularly done in these patients particularly those with hemoglobin > 8gm/dl and high total bilirubin levels. Whilst total to HDL ratio, underlines as a significant diagnostic marker for future cardiac events in these patients. Keywords: β-thalassemia major, triglyceride, HDL-cholesterol, LDL-cholesterol. Table 1: Comparative analysis of serum lipid profile in relation to age Parameters Age ≤15 years n= 24 Age >15 years n= 12 P- value Total lipid 515.7± 121.1 452.9 ±90.6 0.1 * Cholesterol 95.0±17.6 80.9±32.1 0.09 * Serum triglyceride 168.1 ± 109.7 115.2± 40.1 0.1 * HDL cholesterol 19.4±10.2 14.4± 5.9 0.1 * LDL cholesterol 43.1±19.9 40.9±26.6 0.7 * Cholesterol ratio 6.3± 3.4 6.0 ±2.1 0.8 * *Not significant Disclosures No relevant conflicts of interest to declare.

scholarly journals Correlation estradiol levels and physical activities with lipid profile levels of premenopausal women, in Padang city, Indonesia

2019 ◽  
Vol 7 (5) ◽  
pp. 1406
Author(s):  
Hafizah Hafizah ◽  
Afriwardi Afriwardi ◽  
Fika Tri Anggraini ◽  
Delmi Sulastri
Keyword(s):  
Physical Activity ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Ldl Cholesterol ◽  
Premenopausal Women ◽  
Hdl Cholesterol ◽  
Lipid Profiles ◽  
The Mean ◽  
Estradiol Levels

Background: In premenopausal women, low estradiol levels and lack of physical activity can result in dyslipidemia. Dyslipidemia is a risk factor for coronary heart disease (CHD). The incidence of CHD occurs a lot in premenopausal age compared to productive age, the percentage of women who experience higher CHD than men. Objective was to determine the correlation of estradiol levels and physical activity with lipid profiles in premenopausal women in Padang City.Methods: This research was carried out in Padang City. The study was observational, cross-sectional design. The study sample was 79 premenopausal women. Estradiol levels were assessed by the ELISA method, physical activity was assessed by an international physical activity (IPAQ) questionnaire, lipid profiles were assessed by colorimetric enzymatic methods. Correlation of estradiol levels with lipid profile levels were analyzed using the Pearson correlation test. Correlation of physical activity with lipid profile level using the ANOVA test.Results: The mean estradiol level of respondents was 144.68pg/ml, the mean physical activity of respondents is heavy physical activity as much as 41.8%, the mean cholesterol level of respondents was 194.76mg/dl, the mean triglyceride level of respondents was 118.75mg/dl, the mean LDL cholesterol level of respondents was 120.64mg/dl, the mean HDL cholesterol level was 53.18mg/dl.Conclusions: There were significant correlation between estradiol levels with triglyceride levels and LDL cholesterol. There was significant correlation physical activity with total cholesterol levels and triglyceride levels. There was no correlation between estradiol levels with total cholesterol and HDL cholesterol. There was no correlation physical activity with LDL cholesterol and HDL cholesterol.

scholarly journals PERBANDINGAN PROFIL LIPID PADA SERUM DARAH PENDERITA HIPERTENSI DAN NORMOTENSI

Jurnal BIOMA ◽  
2015 ◽  
Vol 11 (2) ◽  
pp. 131
Author(s):  
Pratiwi Widyamurti ◽  
Rusdi Rusdi ◽  
Sri Rahayu
Keyword(s):  
Blood Serum ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Clinical Chemistry ◽  
Hdl Cholesterol ◽  
Mean Value ◽  
Cross Sectional ◽  
Ex Post ◽  
The Mean

ABSTRACT Increased blood pressure more than 140/90 mmHg taken from three measurement in 24 hours can be diagnosed as hypertension. Abnormality of lipid values condition was found at many hypertensive. Based on this reason examination of lipid profile in hypertensive and normotensive should be done. The aim of this research was to measure and compare lipid profile on blood serum in hypertensive    and normotensive. Lipid profile was measured by Konelab 20XT clinical chemistry analyzer. Ex     Post Facto used as method and Cross-sectional used as design. A total of 50 blood samples collected from Hypertensive (N1=25) and normotensive (N2=25) from June to August 2014. SPSS 16.0 was used to analyze the data, T-test was used to compare value of LDL cholesterol, HDL cholesterol and total cholesterol while U Mann-Whitney test was used to compare value of triglyceride. The result      of this research showed that the mean value of triglyceride was 146.56 mg/dL in hypertensive and 143.92 mg/dL in normotensive (p=0.11). The mean value of LDL cholesterol was 129.80 mg/dL in hypertensive and 136.72 mg/dL in normotensive (p=0.62). The mean value of HDL cholesterol was  38.80 mg/dL in hypertensive and 45.04 mg/dL in normotensive (p=0.1). The mean value of total cholesterol was 201.04 mg/dL in hypertensive and 221.88 mg/dL in normotensive (p=0.25). In conclusion, there was no different of lipid profile on blood serum in hypertensive and normotensive.  Keywords: hypertension, lipid profile, normotensive

scholarly journals Pre- and Post-Treatment Values of HDL Cholesterol and Total: HDL Cholesterol Ratio in Hyperlipoproteinaemic Subjects

1981 ◽  
Vol 18 (2) ◽  
pp. 71-75 ◽  
Author(s):  
John K Sale ◽  
James H Johnstone
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Blood Samples ◽  
Male And Female ◽  
Cholesterol Ratio ◽  
Type Iv ◽  
Cholesterol Levels ◽  
The Mean

High-density lipoprotein (HDL) cholesterol, total cholesterol, and triglyceride concentrations were measured in fasting blood samples from 74 controls and 185 patients with untreated primary hyperlipoproteinaemia. The mean HDL cholesterol levels and the total cholesterol: HDL cholesterol ratios were significantly different between male and female subjects. Only patients with Fredrickson type IV hyperlipoproteinaemia had HDL cholesterol concentrations significantly lower than the controls, but all subjects with hyperlipoproteinaemia had total: HDL cholesterol ratios significantly higher than control values. Subsequent investigations were performed on 31 patients during treatment of the hyperlipoproteinaemia by diet alone or in combination with clofibrate. Responses were variable, but generally improvements in the concentrations of triglyceride and total cholesterol were accompanied by an unchanged or decreased total: HDL cholesterol ratio, although there was not necessarily an increase in the HDL cholesterol itself.

scholarly journals Combined Effects of Unhealthy Lifestyle Behaviors on Metabolic Syndrome among Postmenopausal Women

Healthcare ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 848
Author(s):  
Jin-Suk Ra ◽  
Hyesun Kim
Keyword(s):  
Physical Activity ◽  
Sedentary Behavior ◽  
Postmenopausal Women ◽  
Abdominal Obesity ◽  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Dietary Behavior ◽  
Lifestyle Behaviors ◽  
Unhealthy Lifestyle ◽  
Insufficient Physical Activity

This study aimed to identify the combined effects of unhealthy lifestyle behaviors, including diet, sedentary behavior, and physical activity on metabolic syndrome (MS) and components of MS among postmenopausal women. Secondary data analysis was conducted using the Korean National Health and Nutrition Examination Survey (2014–2018) with a cross-sectional study design. Logistic regression analysis was conducted with data from 6114 Korean postmenopausal women. While no significant effects of unhealthy lifestyle behaviors, either individually or as a combination, were found for MS, prolonged sedentary behavior without poor dietary behavior and insufficient physical activity was associated with increased likelihood of abdominal obesity (adjusted odds ratio [AOR]: 1.59, 95% confidence interval [CI]: 1.10–2.29) and impaired fasting glucose (AOR: 1.54, 95% CI: 1.13–2.10). The combination of poor dietary behavior and prolonged sedentary behaviors was also associated with increased likelihood of abdominal obesity (AOR: 1.48, 95% CI: 1.10–2.00) and impaired fasting glucose (AOR: 1.49, 95% CI: 1.14–1.96). In addition, prolonged sedentary behavior and insufficient physical activity together were associated with increased likelihood of abdominal obesity (AOR: 2.81, 95% CI: 1.90–4.20) and impaired fasting glucose (AOR: 1.59, 95% CI: 1.13–2.24). Finally, combining poor dietary behavior, prolonged sedentary behavior, and insufficient physical activity was also associated with increased likelihood of abdominal obesity (AOR: 2.05, 95% CI: 1.50–2.80) and impaired fasting glucose (AOR: 1.71, 95% CI: 1.32–2.23). Strategies for replacing sedentary behavior of postmenopausal women with activities are warranted for prevention of abdominal obesity and impaired fasting glucose.

scholarly journals A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup

2017 ◽  
Vol 21 (2) ◽  
pp. 73-75
Author(s):  
S Vinod Babu ◽  
Anusha R Jagadeesan ◽  
Jothimalar Ramalingam
Keyword(s):  
Comparative Study ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
P Value ◽  
Health Checkup ◽  
Group I ◽  
Significant Difference

ABSTRACT Introduction Obesity is emerging as an epidemic worldwide. Obesity is associated with a number of comorbid conditions, such as diabetes mellitus, hypertension, cancer, dyslipidemia, cardiovascular abnormalities, anemia, obstructive sleep apnea, and psychosocial abnormalities. Aim This study aims at comparing the lipid profile levels of obese and nonobese men. Materials and methods This was a case—control study conducted at a tertiary care center. Totally, 80 men in the age group of 20 to 47 years attending the master health checkup were included in the study, out of which 40 men with normal body mass index (BMI) of 18 to 25 belonged to group I and 40 men with increased BMI of 30 and above belonged to group II. Lipid profile parameters, such as triglycerides (TGLs), total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were estimated in them. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) software version 15.0. Results Statistically significant difference was found in the total cholesterol levels with a p-value of 0.040 while the difference in LDL cholesterol was statistically highly significant with a p-value of 0.040. Conclusion Among lipid profile parameters, only total cholesterol and LDL cholesterol showed significant difference between the obese and nonobese individuals. However, the other parameters like HDL cholesterol and TGLs did not show any significant difference. How to cite this article Babu SV, Jagadeesan AR, Ramalingam J. A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup. Indian J Med Biochem 2017;21(2):73-75.

scholarly journals Effects of Red Pitaya (Hylocereus polyrhizus) on Lipid Profile of Male White Rats (Rattus norvegicus) Receiving High Fat Diet

2018 ◽  
Vol 54 (1) ◽  
pp. 16 ◽  
Author(s):  
Wiwik Werdiningsih ◽  
Suhartati Suhartati
Keyword(s):  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Fruit Peel ◽  
Cholesterol Levels ◽  
White Rats ◽  
Wistar Strain ◽  
Dragon Fruit ◽  
Pap Method

Red dragon fruit (Hylocereus polyrhizus) peel contains anthocyanin, fiber and vitamin C, so it can be used to improve lipid profile in dyslipidemia. The peel of the dragon fruit is not durable, so in this study we used freeze-dried dragon fruit peel. The aim of this study was to prove that the administration of the red dragon fruit peel in a dose of 0.72 g/200 g BW, 1.08 g/200 g BW, and 1.44 g/200 g BW of rat per day for 28 days may improve lipid profile in male wistar strain white rats with high-fat diet. Lipid profiles were studied by examining of total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides. This was a pure experimental study using randomized post test only control group design. This study used experimental animal of 30 male wistar strain white rats which were divided into five groups. Measurements of total, LDL, and HDL cholesterol levels were done by CHOD-PAP method, while triglyceride level was measured with GPO-PAP method. Data were analyzed statistically by One Way Anova test. The results of this study indicated that giving the peel of red dragon fruit as much as 0.72 g lowered total cholesterol levels, 1.08 g lowered total and LDL cholesterol levels, and 1.44 g lowered total cholesterol, LDL cholesterol, triglyceride levels, and raised HDL cholesterol level. Red dragon fruit peel can be used alternatively to improve lipid profile in dyslipidemia.

Abstract P128: Serum Lipid Levels at Adolescence can Predict Adult Dyslipidemia in South Korea - The Kangwha Study

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Jung H Lee ◽  
Hyeon C Kim ◽  
Dae R Kang ◽  
Il Suh
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Logistic Regression ◽  
South Korea ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Serum Lipid ◽  
Hdl Cholesterol ◽  
Multiple Logistic Regression ◽  
Auc Value

Introduction: Several studies have examined tracking pattern of lipid profile level during long follow-up periods in Western countries. However, there have been few such studies in East Asia. Hypothesis: We assessed the hypothesis that there exists tracking pattern of lipid profile level from adolescence to adulthood, and lipid measurements in adolescence can predict adult dyslipidemia in South Korea. Methods: The Kangwha Study was a community-based prospective cohort study that started in 1986 in Kangwha County, South Korea . A total of 400 participants (54% women) whose serum total cholesterol, triglyceride, and high density lipoprotein (HDL) cholesterol level were measured at least once during adolescence (1992-1996), and repeatedly measured at least once during adulthood (2005-2015) were enrolled in our study. Body mass index, waist circumstance, and blood pressure were measured at all measurements. Family history of cardiovascular disease, smoking history, and presence of adult dyslipidemia were checked at adulthood. The tracking pattern of lipid profile level was determined by tracking coefficients (low: <0.30; moderate: 0.30-0.59; moderately high: 0.60-0.89; high: ≥0.90). The tracking coefficients were calculated by Generalized Estimating Equation. The predictability of adult dyslipidemia was assessed by multiple logistic regression and area under curve (AUC) value. Additional analyses were performed to find out whether repeated lipid measurements during adolescence can enhance the predictability of adult dyslipidemia or not. Results: The presence of adult dyslipidemia was 26.3% (105 of 400). Mean age of study participants at enrollment is 13.8 years (SD, 1.6 years), and that at adulthood is 30.1 years (SD, 3.7 years). When adjusted for age, body mass index, waist circumstance, and blood pressure, the tracking coefficient of total cholesterol was 0.59 (95% confidence interval (CI), 0.54-0.63), that of triglyceride was 0.39 (95% CI, 0.28-0.49), and that of HDL cholesterol was 0.51 (95% CI, 0.46-0.55). The AUC value of our multiple logistic regression model on adult dyslipidemia without lipid profile levels at adolescence was 0.77 (95% CI, 0.72-0.83), and that with lipid profile levels at adolescence was 0.80 (95% CI, 0.75-0.85). P value for AUC comparison was significant (p=0.02). In additional analyses, using the average lipid profile levels in multiple lipid measurements at adolescence did not significantly improve the AUC value (p>0.09). Conclusion: In conclusion, moderate tracking patterns of serum lipid profile level were shown in this study. Serum lipid profile measurements at adolescence could help the prediction of adult dyslipidemia. The results of this study supported the need of lipid profile screening at adolescence.

scholarly journals Prevalence, clustering and sociodemographic distributions of non-communicable disease risk factors in Nepalese adolescents: secondary analysis of a nationwide school survey

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e028263 ◽  
Author(s):  
Raja Ram Dhungana ◽  
Bihungum Bista ◽  
Achyut Raj Pandey ◽  
Maximilian de Courten
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Alcohol Consumption ◽  
Vegetable Intake ◽  
Disease Risk ◽  
Communicable Disease ◽  
Fruit And Vegetable Intake ◽  
Fruit And Vegetable ◽  
Insufficient Physical Activity ◽  
Non Communicable Disease

ObjectivesTo assess the prevalence, clustering and sociodemographic distribution of non-communicable disease (NCD) risk factors in adolescents in Nepal.DesignData originated from Global School Based Student Health Survey, Nepal conducted in 2015–2016.SettingThe study sites were the secondary schools in Nepal; 74 schools were selected based on the probability proportional to school enrolment size throughout Nepal.Participants5795 school-going children aged 13–17 years were included in the study.Primary outcomesNCD risk factors: smoking, alcohol consumption, insufficient fruit and vegetable intake, insufficient physical activity and overweight/obesity were the primary outcomes. Sociodemographic distributions of the combined and individual NCD risk factors were determined by Poisson regression analysis.ResultsFindings revealed the prevalence of smoking (6.04%; CI 4.62 to 7.88), alcohol consumption (5.29%; CI 4.03 to 6.92), insufficient fruit and vegetable intake (95.33%; CI 93.89 to 96.45), insufficiently physical activity (84.77%; CI 81.04 to 87.88) and overweight/obesity (6.66%; CI 4.65 to 9.45). One or more risk factors were present in 99.6%, ≥2 were in 83% and ≥3 were in 11.2%. Risk factors were more likely to cluster in male, 17 years of age and grade 7. Prevalence of smoking (adjusted prevalence ratio (aPR)=2.38; CI 1.6 to 3.51) and alcohol consumption (aPR=1.81; CI 1.29 to 2.53) was significantly high in male, and in 16 and 17 years of age. Prevalence of insufficient physical activity and overweight/obesity was significantly lower in higher grades.ConclusionInsufficient fruit and vegetable intake and insufficient physical activity were highly prevalent in the populations studied. Risk factors were disproportionately distributed and clustered in particular gender, age and grade. The study population requires an age and gender specific preventive public health intervention.

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