scholarly journals A Trial Protocol to Investigate the Incidence of Postoperative Bowel Obstruction after Laparoscopic Colorectal Cancer Surgery Using an Absorbable Adhesion Barrier Material (INTERCEED®) (Balsam CEED Study): A Prospective, Multicenter, Observational Study

2021 ◽  
Vol 5 (4) ◽  
pp. 414-418
Author(s):  
Hiromichi Sonoda ◽  
Takeshi Yamada ◽  
Keiji Hirata ◽  
Nobuhisa Matsuhashi ◽  
Daisuke Ichikawa ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Observational Study ◽  
Bowel Obstruction ◽  
Cancer Surgery ◽  
Trial Protocol ◽  
Barrier Material ◽  
Colorectal Cancer Surgery ◽  
Adhesion Barrier ◽  
Multicenter Observational Study ◽  
Prospective Multicenter Observational Study

scholarly journals Absorptive anti-adhesion barrier for the prevention of bowel obstruction after laparoscopic colorectal cancer surgery

2018 ◽  
Vol 2 (1) ◽  
pp. 1-8
Author(s):  
Shoichi Fujii ◽  
Mitsuo Tsukamoto ◽  
Ryu Shimada ◽  
Koichi Okamoto ◽  
Tamuro Hayama ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Bowel Obstruction ◽  
Cancer Surgery ◽  
Colorectal Cancer Surgery ◽  
Adhesion Barrier

scholarly journals A Prospective Multicenter Observational Study of Venous Thromboembolism after Gastric Cancer Surgery (SHISA-1601)

2021 ◽  
pp. 1-10
Author(s):  
Sachiko Kaida ◽  
Toru Miyake ◽  
Satoshi Murata ◽  
Tsuyoshi Yamaguchi ◽  
Takeshi Tatsuta ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Venous Thromboembolism ◽  
Blood Transfusion ◽  
Observational Study ◽  
Characteristic Curve ◽  
Cancer Surgery ◽  
Gastric Cancer Surgery ◽  
Multicenter Observational Study ◽  
Prospective Multicenter Observational Study ◽  
D Dimer

Introduction: This study aimed to clarify the frequency and risk factors of intercurrent venous thromboembolism (VTE) in patients undergoing major curative gastric cancer surgery. Methods: This prospective, multicenter, observational study included patients with gastric cancer who underwent radical gastrectomy at 5 hospitals between June 2016 and May 2018. Patients who were preoperatively administered anticoagulants were excluded. Results: A total of 126 patients were eligible to participate. VTE occurred within 9 days postoperatively in 5 cases (4.0%; 2 symptomatic and 3 asymptomatic). Postoperative day (POD) 1 plasma D-dimer and soluble fibrin (SF) levels were significantly higher in the VTE group than in the non-VTE group. Receiver-operating characteristic curve (ROC) analysis indicated a statistically significant ability of POD 1 D-dimer and SF levels to predict postoperative VTE development after gastrectomy; this finding was reflected by an area under the curve (AUC) of 0.97 (95% CI 0.92–1.0) and 0.87 (95% CI 0.74–1.0), respectively. Cutoff values of D-dimer (24.6 µg/mL) and SF (64.1 µg/mL) were determined. Intraoperative blood transfusion (odds ratio [OR] 7.86), POD 1 D-dimer ≥24.6 µg/mL (OR 17.35), and POD 1 SF ≥64.1 µg/mL (OR 19.5) were independent predictive factors for postoperative VTE (p < 0.05). Conclusion: VTE occurred in 4.0% patients (1.6% symptomatic and 2.4% asymptomatic) after gastric cancer surgery; however, with an early diagnosis and anticoagulant therapy, no patients experienced progression. Careful observation of patients with a high risk for VTE, including intraoperative blood transfusion and high POD 1 D-dimer or SF levels, would contribute to the early detection of VTE.

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